Dmim005335.1
Basic Information
- Insect
- Drosophila mimetica
- Gene Symbol
- lrrfip2_1
- Assembly
- GCA_037075245.1
- Location
- JBAMCH010000005.1:21743093-21745128[-]
Transcription Factor Domain
- TF Family
- LRRFIP
- Domain
- LRRFIP domain
- PFAM
- PF09738
- TF Group
- Unclassified Structure
- Description
- LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 5e-121 9.9e-117 389.7 27.6 1 299 30 320 30 321 0.99 2 2 0.022 4.3e+02 0.1 3.4 209 242 339 371 323 394 0.57
Sequence Information
- Coding Sequence
- ATGGAAAGTATCAGCACCACAGGTCGGCGACGGAACAACATGCGAATCAATGCCGAGGATAATGCCCTGGATCAAATTACAAAAGAGGCGGAAGCGCGACTTGCCGCGCGTCGACAGGCGCGTGCCGAAGCCCGCGAGATCCGCATGAAGGAGCTGGAGCGCCAGCAGAAGGAGCAGGAGATAACCGCCGACCGGGTGTTCGACATGCAGAACGCCACCGCGGTGGGCAGCGAACCCCTCTCGGCGCACCCCGTACGCCTCGTCTACGGCGGCCTGCTAAACGTCACCCGTGCCTCAGCCTCCCGCCGCAGCAGCGAGGACTCCGTGGAGGACGAGGGCAGAAGTTTTCGCGACTTCAAGCACGAGCTTAAGGATGTGGAGGAGCGGTTTCGGAAAGCCATGATAACGAACGCCCAGTTGGACAACGATCGCGCCTCGCAGGCCTACGAGGTGAAGCTGCTGAAGGACAAGTGCGAGATCATGGAGGAGTCGTTTGCACAGCTGCAGCGCGAGTTCAAGGAGAAGATGCGCGACTGCAACGCCCTCAAGCGGAACCTGGACCGCGCCAATCTGGAGCTTAAACTAGTACAAGGACAGCTGAACGAGCGCGACTCGCTGATAGCCGAGCAGGGCCTGCTGATTGTGGCGGTCGAGAATGCCGATGGCAGCGATGCCAAGCGGGCACTAGTGAGTGTGGAGAATGCGAAAGTTCTGGCCTCCGTTCAGGGTTCTCTAGATGTAAGACTTAAGAAGTTCAGTGACGAGAAACAGCGACTGCTGTCCGAGGTGCAAAAGCTTCACGAGCAGCTGGATGAGTATAAGAGTGACGGCATGACTGGACGTCGCAGTCTCTCGCAAGGTTCCTTTGGTGATGAGAATGACTACGAGGCCCAACGGGAATCAAACAAAATCATTTCAGACCATAAATATAAGCTGCAGAAGGCGGAGCAGGAGATCGCCAACTTGCAATCGAGCTTAGCCCGTTCAGAGACTCAAGTAATCAGATACAAAAGCACTGCGGAAGCCGCCGAAAAGGCAGAGGCGGAGTTGAAAGTCGAGCGACGCAAGCTCCAGCGCGAGCACCGGGAAATCCTGGAGAAATTGGAGGAAGCCGAAACGTCAAACAACCATCTGCTGAAACGTCTCGACAAGTTGAAAAACGCTAAGAGTGCCATTCTAAAGGACTTATGA
- Protein Sequence
- MESISTTGRRRNNMRINAEDNALDQITKEAEARLAARRQARAEAREIRMKELERQQKEQEITADRVFDMQNATAVGSEPLSAHPVRLVYGGLLNVTRASASRRSSEDSVEDEGRSFRDFKHELKDVEERFRKAMITNAQLDNDRASQAYEVKLLKDKCEIMEESFAQLQREFKEKMRDCNALKRNLDRANLELKLVQGQLNERDSLIAEQGLLIVAVENADGSDAKRALVSVENAKVLASVQGSLDVRLKKFSDEKQRLLSEVQKLHEQLDEYKSDGMTGRRSLSQGSFGDENDYEAQRESNKIISDHKYKLQKAEQEIANLQSSLARSETQVIRYKSTAEAAEKAEAELKVERRKLQREHREILEKLEEAETSNNHLLKRLDKLKNAKSAILKDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00336724;
- 90% Identity
- iTF_00602585;
- 80% Identity
- -