Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.003 13 6.0 0.0 20 48 77 105 66 109 0.89

2 7 0.0058 25 5.0 0.2 21 45 109 133 102 137 0.83

3 7 0.028 1.2e+02 2.9 0.3 19 45 135 161 133 164 0.83

4 7 0.00061 2.7 8.2 0.7 17 45 161 189 156 192 0.87

5 7 0.002 8.5 6.5 0.6 17 44 189 216 185 220 0.89

6 7 0.0014 5.9 7.1 0.1 21 44 221 244 217 248 0.89

7 7 0.0081 35 4.6 0.3 21 44 249 272 246 279 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.003	13	6.0	0.0	20	48	77	105	66	109	0.89
2	7	0.0058	25	5.0	0.2	21	45	109	133	102	137	0.83
3	7	0.028	1.2e+02	2.9	0.3	19	45	135	161	133	164	0.83
4	7	0.00061	2.7	8.2	0.7	17	45	161	189	156	192	0.87
5	7	0.002	8.5	6.5	0.6	17	44	189	216	185	220	0.89
6	7	0.0014	5.9	7.1	0.1	21	44	221	244	217	248	0.89
7	7	0.0081	35	4.6	0.3	21	44	249	272	246	279	0.84

Coding Sequence: ATGGCACAAGCGATAGATGTGGCGTGCGTGAAGGAAGAGCACTGCGAGGCCATTTGCAACATGTTCAAGACTCAGGATTGGCAATTAACAATGCGACACAGGGATTTGGGCCTGGTCAAGATCGAGCAGGACATGAGTTTTGTGTGGCAGAGCAGCGCCAATGCCAACGGCATGGACGGCAAACAGCGCCAGGCAGCAGAGAAACAAACACTCAAAAAATTTCAGAATGGCAGCGAGAAGCCTTTCAAGTGCGCCCACTGTCCTAAGGACTTTGCAACTAGCAGCAATCTTAAGGTGCATCTCACGCGCACACACTCGGGAGATCGCGAGCGACCCTTTCTCTGTCCCACCTGCCCGAAGTCGTTTGCGACCAACGATAATCTGCAAAAGCACATACGTCGCCATTCGAACGAAAGGACACTCAGTTGCCCACACTGCCCCAAGCTGTTTGCCACCAAGGACAATCTGCAGAAGCACATACGTCGACACTCCAGCGAAAGGACGCTCACTTGCCCGCACTGTCCGAAGGCCTTTGCCACCAACGACAATCTGCAGAAGCACATACGCCGCCATTCGAGTGAAAGGACCCTCAATTGTCCGCACTGCCCGAAGGCGTTTGCGACCAACGATAATCTACAGCGACACATACGCGGCCACACGGGCGAGCGACCCTTCAAGTGTCCCTATTGTCCCAAGCCGTTCGCCCAAAATCGAGATCTCAAAGCACACATACTGGAGCACACGGGCGAGAAGCCCTACAAGTGTCCACACTGCCCCAAGGCGTGCGTACGCAGCGAGGGCCTGAAGAAGCACATACTGCGGCTGCACAAAGACATCGAGCCGGAGCCCCAGACGACAGCCAAACATTGGCAAACGGATAAAACTTTCGCGGCAGACTCGAATGGACGCGTCTTCATGTACAAATACGATCTAACTAAGCAAACGCGATTACCCACGGGCGAGGCAtaa
Protein Sequence: MAQAIDVACVKEEHCEAICNMFKTQDWQLTMRHRDLGLVKIEQDMSFVWQSSANANGMDGKQRQAAEKQTLKKFQNGSEKPFKCAHCPKDFATSSNLKVHLTRTHSGDRERPFLCPTCPKSFATNDNLQKHIRRHSNERTLSCPHCPKLFATKDNLQKHIRRHSSERTLTCPHCPKAFATNDNLQKHIRRHSSERTLNCPHCPKAFATNDNLQRHIRGHTGERPFKCPYCPKPFAQNRDLKAHILEHTGEKPYKCPHCPKACVRSEGLKKHILRLHKDIEPEPQTTAKHWQTDKTFAADSNGRVFMYKYDLTKQTRLPTGEA

Sequence clustering based on sequence similarity using MMseqs2