Basic Information

Insect: Drosophila merina
Gene Symbol: -
Assembly: GCA_035047645.1
Location: JAWNPH010000089.1:6334695-6340229[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0033 0.3 11.8 0.3 1 23 144 166 144 166 0.97

2 15 3.4 3.1e+02 2.3 5.8 1 23 172 195 172 195 0.97

3 15 3.5e-05 0.0031 18.1 2.5 1 23 374 396 374 396 0.98

4 15 2.4 2.2e+02 2.8 2.0 1 23 402 425 402 426 0.92

5 15 2 1.9e+02 3.0 0.2 1 23 445 468 445 468 0.92

6 15 0.00098 0.089 13.5 1.9 3 23 722 742 721 742 0.92

7 15 0.039 3.6 8.4 1.4 1 23 748 771 748 771 0.98

8 15 9.4 8.6e+02 1.0 1.4 3 23 809 829 807 830 0.76

9 15 0.002 0.18 12.5 0.4 1 23 851 874 851 874 0.97

10 15 0.01 0.92 10.3 0.4 1 23 1068 1090 1068 1090 0.96

11 15 0.0053 0.48 11.2 5.1 1 23 1102 1124 1102 1124 0.98

12 15 1.7e-05 0.0015 19.1 0.8 2 23 1130 1152 1129 1152 0.94

13 15 0.0028 0.25 12.1 5.0 1 23 1158 1183 1158 1183 0.95

14 15 0.00025 0.023 15.4 2.6 1 23 1188 1210 1188 1210 0.97

15 15 0.07 6.4 7.6 0.3 1 14 1216 1229 1216 1239 0.72

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0033	0.3	11.8	0.3	1	23	144	166	144	166	0.97
2	15	3.4	3.1e+02	2.3	5.8	1	23	172	195	172	195	0.97
3	15	3.5e-05	0.0031	18.1	2.5	1	23	374	396	374	396	0.98
4	15	2.4	2.2e+02	2.8	2.0	1	23	402	425	402	426	0.92
5	15	2	1.9e+02	3.0	0.2	1	23	445	468	445	468	0.92
6	15	0.00098	0.089	13.5	1.9	3	23	722	742	721	742	0.92
7	15	0.039	3.6	8.4	1.4	1	23	748	771	748	771	0.98
8	15	9.4	8.6e+02	1.0	1.4	3	23	809	829	807	830	0.76
9	15	0.002	0.18	12.5	0.4	1	23	851	874	851	874	0.97
10	15	0.01	0.92	10.3	0.4	1	23	1068	1090	1068	1090	0.96
11	15	0.0053	0.48	11.2	5.1	1	23	1102	1124	1102	1124	0.98
12	15	1.7e-05	0.0015	19.1	0.8	2	23	1130	1152	1129	1152	0.94
13	15	0.0028	0.25	12.1	5.0	1	23	1158	1183	1158	1183	0.95
14	15	0.00025	0.023	15.4	2.6	1	23	1188	1210	1188	1210	0.97
15	15	0.07	6.4	7.6	0.3	1	14	1216	1229	1216	1239	0.72

Sequence Information

Coding Sequence: ATGGCGTTAAACAAAAGGTTGAGCTCCCAAGCGGACGGAGAGGACTTCAAGTTTGCGTGTCGCTGCTGTCTGAAGATGAACACCGAGCTACTCAAGCTGGACTCTGTGACTGTGGCGCGCAGTCTGGATCCGGCGGAGGCAAAGGAGAAGATTCCCCTGCTACGCTGCCTGCTCTACTGTACACGCGGCGAAAATCCGGCGGAGCTGCCCCAGTACATCTGTAACGAGTGCAGCCAGAGCCTTCAGGTCGCCTACTACTTTATCCAGAATTCAATTCGTGCGCACGAGATCCTGTGTCGCAAACTGTGCCCGAGCAAAGCTTCCAGGACTGCCCAGATGACGCGGTTCAACGGCTGCCTGGGCCAGGAGCTGGAGGAACACTTGGAGGGCGACACCGACAGGACGAAATTCTTGAAAAAAACCATGCGCCACGAGTGCCAGGTGTGCGGAGTTATCGTCTACAATCGCCTGGAACTGAAGCAGCACATACGCTTACATGCAGATGGCCTCGCTTACCACTGCAAAATGTGCAACTATTCAACACTGAAGCAGCGGCTGTTGCACGATCATTATCGCTCAATCCACAACCAAAACGCCGCTCAGGCCGAGGAGCTTTCGAAGGTGAAACCTGAGGCCACGAAGCCGGAAGAGGAGGTCAAGGTGTGCACGCTGGAGGACATGGAGCTGCTGATACCCACAGTTCTGACGCCGGAGGACTACTCTACGGTGCCGATCGATGCGGACCAACTGCGGGACATTGAACAGCAGCTGGCGGCCACAATGGGCGAAACAGTGCCGGCGGTGGACACACTAACCTCCACATTGCCGCCAATGGAGTCCCAAAACGTGAGCATCGGCACGGAGTATCTGGTCTTGCCAGACGGATCCCTACAGCAGGTCAACGGTGGCGGCGTGGTTATTGAGTACATCGACGATAGCAAGCCTACAAATTCCAATTCCCATCCGACCCCCTCTATCAACATTAACTTGCAAAACCTTCTCGGCGGCGACGAGAACGAAGGAATGGACATTGATGTCAATGAGCTGATTGTGGAGGATGTGTTGCCGCAAATCAAAGTAACGCCAAAGCCAGCGCCTCTCGGATCTCCAGTGTACAAGCACAAATGCAAATTGTGCCCTAAAACATTTGCCACTTTGGCACGTCTGAAATCTCATCAGTTGACGCACAGCCATTTGCCCAAGTTTTTCTGCGATCAGTGCGATTACTACTCGTTGCGCAGTGCCGATCTCATTCAGCACTATCAGAACCAGCACCACCGGTCCGAGGGGCTAGCGGAGAAATCGGATATCACGAAGCAGGATGCGCGTACATATTCCTGTGATATGTGTCTGTTTGAGACGCCGACAGTCAATGAACTTCGCATCCACTATGCCCAGAGTCATACGGTGCAGCCGACGGAAGTGGAGCTGCGTCCCAGCTGGACGACTGATAATGGTAGTGCTAAGGCAGACGATGCATGTTGCGCGATCAACGAAAAGCAGCCAGCTTTATTGTCAAACTCTTCCGAAACCCACGTGCCCATTAAATGTGATCCTGCAGTTGCAGACACACAAGGGCAATTCGAGCAACTGCCGGTGGCATCCATGGCGAGCGTTGCCCAAACCGAAGCCATCAATGCGGTGGTAGATGCCACGCCGAATTTTTTTGTGGGCACTTCCAATTCCATTGCGGCGCCAGTGACATCCATTGCCGAAAGCGCTGGGGGAGCTCCATGCGGCTCATTCGAAATGTTCCCTGAAATCTCTCAAGCCAATTTGTCGATTAATGAATCTATTCCGCAAGCGCCGGCCAATATTTCCAATTCAAACATTTCCATGTTCGGCGACATGCAGGATTTTATTGACAACACCGACGTGGCTGCCATATGCACCATTCCAGCCGACGACATGCCCGTGGTCGATGGTGACGACATCGTAATTGATAATAATAACATCAGCCTGGACTTTGATGCCGAAAACTTGTTCGAAGACttcgaagaggaggaggaggctgcCGCGGCAGAGGAGGATGATGATGGCGAAAACGAAGATGAGAATGAGAACAATGATACAGCCACTGATCAAAATCTGCTGCTAACCAGTGACGACGATGACGTCGACGATTTTGATGACGAGCAGTCTAAGCATCTCCAGAAGCCTTACTGCATTTACTGCAACAAAAAGTTCACCAGTCAGTACAAATTTGAGAATCACATGTTTGTCCATCGCGGTCTGGCTCCTTACCGCTGCGAATTGTGTACCAATCTGTACAATATGAAGCGACTTCTGATCAGGCATTATAAAACCGTGCACAAAAGAATGCCCACAAGGGACATGGTCCAGGCCAAGGGTGACAAGGTTACGGTGGCGCGATCTAGCCTTGAAAAGATCGAATTTAATTCAAATAAGAATCCCATGCTGATGTGCGCAAAGTGTCCGTTCGAGTGCGAGTTGGATGGAGAGATGCGAAAGCATTTGAATGCCCACCACGGCATCAACGACGGAGTATCTCTGCATGCCAACGAAGTGTTTATAATACGCAAACTGCCTTTTGAGTGTCCGCGCTGCATTCGCTCGTTTGCGGCCAAGAGCACCCTTGTTAGGCATCTGCAGCGAAGCCATTTGGTGGAGACCATCATCGAAGCGCCAGCACCACATGCAACAGCCAGTTCAGCGGCGACAACCACAACGACGACGGCCACGGCGACCACATCCGGGCCGGCCAACCACAGTCAAGATGAGGATAAGGCAGAACGCAAGATGACAATGTCGCCGACTGCTGCTGAAAGTGGCGTTGGCGATGGCAATGGGGAATGCGAGGGAACAAGCAGAGATGATGATGGAGCCATAGCAGGAGAAGGAACTTCAATTAAATCGGAATTAGCACTACCCAAAGAAGAGTACGATGTCGATGGAGCGGCAGCACATCCTGGAGCCATAGCCGCAACATCAGCCACGTCGCCCATTACCACCACTGTCTCAACCACATCAGGCACTTTCTCCACACTGTTTCCCACTCCCACGCCATTTGACTTAGATTGTGATCTGATTTCCGATGTCCCAGCCCCGCAGAACATATCCGCGTCCAATACCAATTCCAATCCCAGCGTACTTTTAAATGGCAGCGACAAGTTTCTACCCGCTTTGTCGCCAGCGGAGAAATGCCTACCTTCCAATTCGCGGCTTCCACGCTCCCCAACATACAAGTGCAAGCTGTGCAGCGAGGCCTTTGACGAACTGGGGAAGCTGGTCAAGCACGAGATGTTCCACTCAAACACGGACTCTTCCCGAGCGGGCTATCAACATAAATGCACCATTTGCAATACCAGCTACCGCAATCTAACTTTGTTAAAGTTCCACATGAAGCGGCATatgaaatgcaaaatgcaatgCAAACTTTGCCCAAAGACTTTCGCCACCAGCCAGGAGCTCGAACGTCACACGAAGGCCAAGCATATGCGGCAGAGTACGTTCCGCTGCAATTTGGACAACTGTAAGAAGACGTTCGCGTACAAGCACCACATGGTGCGACATCAGAACGCCTCGCATTTGCAGACCCGGCACGTGTGCACCATATGCGACAAGGAGCTGATGACTAGCCAGCATCTGCGGAACCACATGTCCATACACAAAGGTGGAACGTCCTACAAGTGTCCCTATTGCGATCGAACGTATTTGCGTCGGGGACGTATCGGTGCCCATGTTCTAAAAGTTCATAAAATAAAGTTAAGCGATGAGGAGCTGGCCGTTTTCCTTCGCGAAACCGTGAGGGCGATAAACCGCCAGGGACAGCTAGTGCGGCGAAAAGAAGAAGTTAAAGAAGATATATCACCATAA
Protein Sequence: MALNKRLSSQADGEDFKFACRCCLKMNTELLKLDSVTVARSLDPAEAKEKIPLLRCLLYCTRGENPAELPQYICNECSQSLQVAYYFIQNSIRAHEILCRKLCPSKASRTAQMTRFNGCLGQELEEHLEGDTDRTKFLKKTMRHECQVCGVIVYNRLELKQHIRLHADGLAYHCKMCNYSTLKQRLLHDHYRSIHNQNAAQAEELSKVKPEATKPEEEVKVCTLEDMELLIPTVLTPEDYSTVPIDADQLRDIEQQLAATMGETVPAVDTLTSTLPPMESQNVSIGTEYLVLPDGSLQQVNGGGVVIEYIDDSKPTNSNSHPTPSININLQNLLGGDENEGMDIDVNELIVEDVLPQIKVTPKPAPLGSPVYKHKCKLCPKTFATLARLKSHQLTHSHLPKFFCDQCDYYSLRSADLIQHYQNQHHRSEGLAEKSDITKQDARTYSCDMCLFETPTVNELRIHYAQSHTVQPTEVELRPSWTTDNGSAKADDACCAINEKQPALLSNSSETHVPIKCDPAVADTQGQFEQLPVASMASVAQTEAINAVVDATPNFFVGTSNSIAAPVTSIAESAGGAPCGSFEMFPEISQANLSINESIPQAPANISNSNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEEEEEAAAAEEDDDGENEDENENNDTATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVTVARSSLEKIEFNSNKNPMLMCAKCPFECELDGEMRKHLNAHHGINDGVSLHANEVFIIRKLPFECPRCIRSFAAKSTLVRHLQRSHLVETIIEAPAPHATASSAATTTTTTATATTSGPANHSQDEDKAERKMTMSPTAAESGVGDGNGECEGTSRDDDGAIAGEGTSIKSELALPKEEYDVDGAAAHPGAIAATSATSPITTTVSTTSGTFSTLFPTPTPFDLDCDLISDVPAPQNISASNTNSNPSVLLNGSDKFLPALSPAEKCLPSNSRLPRSPTYKCKLCSEAFDELGKLVKHEMFHSNTDSSRAGYQHKCTICNTSYRNLTLLKFHMKRHMKCKMQCKLCPKTFATSQELERHTKAKHMRQSTFRCNLDNCKKTFAYKHHMVRHQNASHLQTRHVCTICDKELMTSQHLRNHMSIHKGGTSYKCPYCDRTYLRRGRIGAHVLKVHKIKLSDEELAVFLRETVRAINRQGQLVRRKEEVKEDISP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00504202;
90% Identity: iTF_00615113;
80% Identity: -