Derc013384.1
Basic Information
- Insect
- Drosophila ercepeae
- Gene Symbol
- -
- Assembly
- GCA_018150545.1
- Location
- JAECWL010000161.1:6304270-6309789[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0032 0.23 11.8 0.3 1 23 144 166 144 166 0.97 2 15 3.3 2.3e+02 2.3 5.8 1 23 172 195 172 195 0.97 3 15 3.4e-05 0.0024 18.1 2.5 1 23 374 396 374 396 0.98 4 15 2.3 1.6e+02 2.8 2.0 1 23 402 425 402 426 0.92 5 15 2 1.4e+02 3.0 0.2 1 23 446 469 446 469 0.92 6 15 0.00096 0.067 13.5 1.9 3 23 723 743 722 743 0.92 7 15 0.038 2.7 8.4 1.4 1 23 749 772 749 772 0.98 8 15 9.2 6.4e+02 1.0 1.4 3 23 810 830 808 831 0.76 9 15 0.002 0.14 12.5 0.4 1 23 852 875 852 875 0.97 10 15 0.0028 0.19 12.0 0.2 1 23 1068 1090 1068 1090 0.98 11 15 0.0051 0.36 11.2 5.1 1 23 1102 1124 1102 1124 0.98 12 15 1.6e-05 0.0011 19.1 0.8 2 23 1130 1152 1129 1152 0.94 13 15 0.0027 0.19 12.1 5.0 1 23 1158 1183 1158 1183 0.95 14 15 0.00024 0.017 15.4 2.6 1 23 1188 1210 1188 1210 0.97 15 15 0.069 4.8 7.6 0.3 1 14 1216 1229 1216 1239 0.72
Sequence Information
- Coding Sequence
- ATGGCGTTAAACAAAAGGTTGAGCTCCCAAGCGGACGGAGAGGACTTCAAGTTTGCGTGTCGCTGCTGTCTGAAGATGAACACCGAACTACTCAAGCTGGACTCTGTGACTGTGGCGCGCAGTCTGGATCCGGCGGAGGCAAAGGAAAAGATTCCCCTACTACGCTGCCTGCTCTACTGTACACGCGGCGAAAATCCGGCGGAGCTGCCCCAGTATATCTGTAACGAGTGCAGCCAGAGCCTTCAGGTCGCCTACTACTTCATCCAGAATTCGATTCGTGCGCACGAGATCCTGTGTCGCAAACTGTGCCCAAGCAAAGCTTCCCGAACTGCCCAGATGACGCGGTTCAACGGTTGCCTCGGCCAGGAGCTGGAAGAGCACTTGGAGGGCGACACCGACAGGACGAAGTTCTTGAAAAAAACCATGCGCCACGAGTGCCAGGTGTGCGGAGTTATCGTCTACAATCGCCTGGAGCTGAAACAGCACATACGCTTACATGCAGATGGCCTCGCTTACCACTGCAAAATGTGCAACTATTCAACACTGAAGCAGCGGCTGTTGCACGATCATTATCGCTCAATCCACAACCAAAACGCCACTCAGGCCGAGGAGCTTTCCAAGGTGAAACCTGAGGCCGCGAAGCCGGAAGAGGAGGTCAAGGTGTGCACGCTGGAGGACATGGAGCTGCTGATACCCACAGTACTGACGCCGGAAGACTACTCGACGGTGCCGATCGATGCGGACCAGCTGCGGGACATTGAACAGCAGCTGGCGGCCACAATGGGCGAAACAGTGCCGGCGGTGGACACCCTAACCTCCACATTGCCGCCAATGGAGTCCCAAAACGTGAGCATCGGCACGGAGTATCTGGTCTTGCCGGACGGATCCCTACAGCAGGTCAACGGTGGCGGCGTGGTTATTGAGTACATCGACGATAGCAAGCCTACAAATTCCAATTCCCATGCGGCCCCCTCTATCAACATTAACTTGCAAAACCTTCTAGGCGGCGACGAAAACGAGGGCATGGACATTGATGTCAATGAGCTAATTGTGGAGGATGTGTTGCCGCAAATTAAAGTAACGCCAAAGCCAGCGCCTCTCGGATCTCCAGTGTACAAGCACAAATGCAAATTGTGCCCTAAAACATTTGCCACTTTGGCACGTCTGAAATCTCATCAGTTGACGCACAGCCATTTGCCCAAGTTTTTCTGCGATCAGTGCGATTACTACTCGTTGCGCAGTGCCGATCTCATTCAGCACTATCAGAACCAGCACCACCGCTCCGAAGGGCTGGCGGATAAATCGGCGGATGGCATCAAGCAGGATGTGCGTACATATTCCTGTGATATGTGTCTGTTTGAGACGCCGACAGTCAATGAACTTCGCATCCACTATGCCCAGAGTCATACGGTTCAGCCGACGGAAGTGGAGCTGCGTCCCAGCTGGACGACTGATAATGGTAGTGCTAAGGCAGACGATGCATGTTGCACGATCAACGAAAAGCAGCCAGCTTTATTGTCAAACTCTTCCGAAACCCACGTGCCCATTAAATGTGATCCTGCAGTTGCAGACACTCAAGGGCAATTCGAGCAACTGCCGGTGGCATCAATGGCGAGCGTTGCCCAAACCGAAGCCATCAATGCGGTGGTAGATGCTACACCGAATTTTTTTGTGGGCACTTCCAATTCCATTGCGGCTCCAGTGACATCCATTGCCGAAAGCGCTGGGGGAGCTCCATGCGGCTCATTCGAAATGTTCCCTGAAATCTCTCAAGCCAATTTGTCGATTAATGAATCTATTCCGCAAGCGCCGGCCAATATTTCCAATTCAAACATTTCCATGTTCGGCGACATGCAGGATTTTATTGACAACACCGACGTGGCTGCCATATGCACCATTCCAGCCGACGACATGCCCGTGGTCGATGGTGACGACATCGTAATTGATAATAATAACATCAGCCTGGACTTTGATGCCGAAAACTTGTTCGAAGACTTCGAAGAGGAGGAGGAGGCTGCCGCGGCAGAGGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCAGTCGAAGCATCTCCAGAAGCCTTACTGCATTTACTGCAACAAAAAGTTCACCAGTCAGTACAAATTTGAGAATCACATGTTTGTCCATCGCGGTCTGGCTCCCTACCGCTGCGAATTGTGTACCAATCTGTACAATATGAAGCGACTTCTGATCAGGCATTATAAAACCGTGCACAAAAGAATGCCCACAAGGGACATGGTCCAGGCCAAGGGTGACAAGGTTACGGTGGCGCGGTCTAGCCTTGAAAAGATCGAATTGAATTCAAATAAGAATCCCATGCTGATGTGCGCAAAGTGTCCGTTCGAGTGCGAGTTGGATGGAGAGATGCGAAAGCATTTGAATGCCCACCACGGCATCAACGACGGAGTATCTCTTCATGCCAACGAAGTGTTTATAATACGCAAACTGCCTTTTGAGTGTCCGCGTTGCATTCGATCGTTTGCGGCCAAGAGCACCCTAGTGCGCCATCTGCAGCGAAGCCATTTGGTGGAGACCATCATCGAAGCGCCAGCACCACATGCAACAGCCAGTTCAGCGGCAACAACCACAACGACGACGGCCACGGCGACCACATCCGGGCCGGCCAACCACAGTCAAGATGAGGATAAGCCACAACTCAAGATGACAATGTCGCCGACTGCTGCTGAAAGTGGCGTTGGCGATGGCAATGGGGAATGCGAGGGAACAAGCAGAGATGATGGAGCCATAGCAGGAGAAGGAACTTCAATTAAATCGGAATTAGCACTACCCAAAGAGGAATACGATGTCGATGGAGCGGCAGCACATCCTGGAGCCATAGCCGCAACATCAGCCACGTCGCCCATTACCACCACTGTCTCAACCACATCAGGCACTTTCTCCACACTGTTTCCCACTCCCACGCCGTTTGACTTAGATTGTGATCTGATTTCTGATGTACCAGCCCCGCAGAACATATCCGTGTCCAATACCAATTCCAATCCCAGCGTACTTTTAAATGGCAGCGACAAGTTTCTACCCGCTTTGTCGCCAGCAGAGAAATGCCTGCCCTCCAATTCGCGGCTTCCACGCTCCCCAACATACAAGTGCAAGCTGTGCAGCGAGGCCTTTGACGAACTGGGGAAGCTGGTTAAGCACGAGATGGTCCACTCAAACACGGACTCTTCTCGAGCGGGCTATCAACATAAATGCACTATTTGCAATACCAGCTACCGCAATCTAACTTTGTTAAAGTTCCACATGAAGCGACATATGAAGTGCAAAATGCAGTGTAAACTTTGCCCAAAGACTTTCGCCACCAGCCAGGAGCTCGAACGTCACACGAAGGCCAAGCATATGCGGCAGAGTACGTTCCGCTGCAATTTGGACAACTGTAAGAAGACGTTCGCGTACAAGCACCACATGGTGCGGCATCAGAACGCCTCGCATTTGCAGACCCGGCACGTGTGCACCATATGCGACAAGGAGCTGATGACTAGCCAGCATCTGCGGAACCATATGTCCATACACAAAGGTGGAACGTCCTACAAATGTCCCTATTGCGATCGAACGTATTTGCGTCGGGGACGTATCGGTGCCCATGTTCTAAAAGTTCATAAAATAAAGTTAAGCGATGAGGAGCTGGCCGTTTTCCTTCGCGAAACCGTGAGGGCGATAAACCGCCAGGGACAGCTAGTGCGGCGAAAAGAAGAAGTTAAAGAAGATATATCACCATAA
- Protein Sequence
- MALNKRLSSQADGEDFKFACRCCLKMNTELLKLDSVTVARSLDPAEAKEKIPLLRCLLYCTRGENPAELPQYICNECSQSLQVAYYFIQNSIRAHEILCRKLCPSKASRTAQMTRFNGCLGQELEEHLEGDTDRTKFLKKTMRHECQVCGVIVYNRLELKQHIRLHADGLAYHCKMCNYSTLKQRLLHDHYRSIHNQNATQAEELSKVKPEAAKPEEEVKVCTLEDMELLIPTVLTPEDYSTVPIDADQLRDIEQQLAATMGETVPAVDTLTSTLPPMESQNVSIGTEYLVLPDGSLQQVNGGGVVIEYIDDSKPTNSNSHAAPSININLQNLLGGDENEGMDIDVNELIVEDVLPQIKVTPKPAPLGSPVYKHKCKLCPKTFATLARLKSHQLTHSHLPKFFCDQCDYYSLRSADLIQHYQNQHHRSEGLADKSADGIKQDVRTYSCDMCLFETPTVNELRIHYAQSHTVQPTEVELRPSWTTDNGSAKADDACCTINEKQPALLSNSSETHVPIKCDPAVADTQGQFEQLPVASMASVAQTEAINAVVDATPNFFVGTSNSIAAPVTSIAESAGGAPCGSFEMFPEISQANLSINESIPQAPANISNSNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEEEEEAAAAEEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVTVARSSLEKIELNSNKNPMLMCAKCPFECELDGEMRKHLNAHHGINDGVSLHANEVFIIRKLPFECPRCIRSFAAKSTLVRHLQRSHLVETIIEAPAPHATASSAATTTTTTATATTSGPANHSQDEDKPQLKMTMSPTAAESGVGDGNGECEGTSRDDGAIAGEGTSIKSELALPKEEYDVDGAAAHPGAIAATSATSPITTTVSTTSGTFSTLFPTPTPFDLDCDLISDVPAPQNISVSNTNSNPSVLLNGSDKFLPALSPAEKCLPSNSRLPRSPTYKCKLCSEAFDELGKLVKHEMVHSNTDSSRAGYQHKCTICNTSYRNLTLLKFHMKRHMKCKMQCKLCPKTFATSQELERHTKAKHMRQSTFRCNLDNCKKTFAYKHHMVRHQNASHLQTRHVCTICDKELMTSQHLRNHMSIHKGGTSYKCPYCDRTYLRRGRIGAHVLKVHKIKLSDEELAVFLRETVRAINRQGQLVRRKEEVKEDISP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00546187; iTF_00615113;
- 90% Identity
- iTF_00615113;
- 80% Identity
- -