Basic Information

Insect: Drosophila merina
Gene Symbol: -
Assembly: GCA_035047645.1
Location: JAWNPH010000002.1:18080425-18087058[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0067 0.62 10.8 0.1 1 23 1299 1322 1299 1322 0.95

2 13 6.7 6.1e+02 1.4 0.2 1 23 1474 1496 1474 1496 0.91

3 13 0.00015 0.014 16.1 2.7 2 23 1499 1520 1499 1520 0.97

4 13 5.8e-05 0.0053 17.4 0.2 3 23 1528 1548 1526 1548 0.98

5 13 4.8e-07 4.4e-05 23.9 4.1 2 23 1555 1576 1554 1576 0.97

6 13 4.5 4.1e+02 1.9 0.4 5 23 1589 1607 1587 1607 0.96

7 13 1.1 1e+02 3.9 5.4 3 23 1614 1635 1612 1635 0.93

8 13 0.029 2.6 8.9 0.2 2 23 1646 1666 1645 1666 0.96

9 13 1.5e-05 0.0014 19.2 0.6 1 19 1672 1690 1672 1694 0.95

10 13 2.9e-05 0.0027 18.3 0.4 1 23 1702 1724 1702 1724 0.98

11 13 8.6e-05 0.0079 16.8 7.6 1 23 1730 1752 1730 1753 0.96

12 13 0.00039 0.035 14.8 6.6 1 23 1758 1780 1758 1780 0.98

13 13 0.0022 0.2 12.4 6.1 1 23 1786 1808 1786 1809 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0067	0.62	10.8	0.1	1	23	1299	1322	1299	1322	0.95
2	13	6.7	6.1e+02	1.4	0.2	1	23	1474	1496	1474	1496	0.91
3	13	0.00015	0.014	16.1	2.7	2	23	1499	1520	1499	1520	0.97
4	13	5.8e-05	0.0053	17.4	0.2	3	23	1528	1548	1526	1548	0.98
5	13	4.8e-07	4.4e-05	23.9	4.1	2	23	1555	1576	1554	1576	0.97
6	13	4.5	4.1e+02	1.9	0.4	5	23	1589	1607	1587	1607	0.96
7	13	1.1	1e+02	3.9	5.4	3	23	1614	1635	1612	1635	0.93
8	13	0.029	2.6	8.9	0.2	2	23	1646	1666	1645	1666	0.96
9	13	1.5e-05	0.0014	19.2	0.6	1	19	1672	1690	1672	1694	0.95
10	13	2.9e-05	0.0027	18.3	0.4	1	23	1702	1724	1702	1724	0.98
11	13	8.6e-05	0.0079	16.8	7.6	1	23	1730	1752	1730	1753	0.96
12	13	0.00039	0.035	14.8	6.6	1	23	1758	1780	1758	1780	0.98
13	13	0.0022	0.2	12.4	6.1	1	23	1786	1808	1786	1809	0.96

Sequence Information

Coding Sequence: ATGGTCGACAACAGCGTTCAGTGCCCCGTGTGCACCTTGTACCTGCATGCGGGCATGAATCTTTCCGATCACCTGGAGACCCATCCCAAGGAGCAGGTGATCAAGGCACTGGTGCAGATGACGATCGTAGGGAGTGGGAGCGGCGGTAGTGCTCTGGCTGCCGCAATGCTGGCAGGAGCAGGATCAGGATCAAGTGGCAGTGCAGCGAATACTGCTGAGAGCATTGCAATCGACGACAAAACAGCCATTACACCTTTGAATGTCGAAGTCAAACCAGTTGTGGCACCCAAATCCATATCAGCTGGTGCCTCTGCGGTACAGACACCACCGCAGTCGCAGTTGCAGTCGCAGCCACAGCCGCAagcgccgccgccgccgctttCCTCAACTCTACCAGCACCCGCCAGCACCACCTCTACCTCCGCCACCGCTGCAAACAGCTCCAAATCCCCAAATAGCAACAAACTGAGCAATCCACCGATAAAAGCAATGAAATGCTCACCGCCCCCGACTGAAGCGCGATCCAGCACATCCGCACATCCCACCACAAGCATGTCCAGTAGTCTCTACCAACCAACTCTGGTTGCTCCAGATTACCGCTTtaatcaacagcagcagccgcaacaGCAACCAATGTTCGGGCGTGGCAGCAACGCTCCGACAGCCACACTGGTGATTCCTCAAGTGTCCCAGCAACACTTTCTCACCACCAACCCCCAGCAACAGGCACACTTCTCCCATCAGCAACAGcctccacagcagcagcagcagcagcaacatcaacagcagcCTGCCCTTAAATATACCTACGCCACGGCTTTGCCGCCGCCTCCTCCGCTGCAGCTCTTtacgcagcagcagccaatGCAGCAGCCGGCAACTTCATCGCAAACCAATTCGCCGCCGCACGCGAAACCTCCGCCCGCCTATGGAGCCGCTATCAGTCAAATAAGATCTCAGCACAACCAAAACAaacagcagccacagcagcagcaacagttgcaGCCGCAACAACCACACCTAACCGTGCACCACAATCACAATCACAACTTAACCCTGACACCACCGACAGCTGGCAAGCAGCTCGTTTCTGGCAAAGCTCATTCGGAGGTCTTCTTGAATCCCCCACCACCTCCGTCGCAAACACAGGGCCAGCAGAATCTTGGGCATCAGCAGAATCAAAATTTGAGCACACATGCCAGCCCCCAGCTGCTGGGGACAGCGTCCTCCAATAGATTGTTGCAGCAGCATCAGCCCCTGGGGATGCCGATTTACGTTTCCGGATCAGGAGCCAGCAGCACCCACTCTAGTTCCAGCTCCAGCCACTCTCTTCCGATGAATGCATCCAGCGCCAGCACGTGCGCCAGCATTCGTGGCCATCGTCAGACCAACTCACCCTTTGGAGCACTTCTCAATGCTGCGGCAGCTGTGGCGTGTCCTTCGCCTGCCTCCTCGAGCGCATCGTCGTCGGTGCTGCGCTACGCGGAGTCACCGGTGGCGCATTACTTGGAGCGGGAAAACGGGGACTTTATTGTCCAGGAGACACCCAAGCACATTGTCGAGTGTGTCGAAAAGGAGGATGGCGAGTTCTCTGTGATTGAGCGTATATATCAGTCGCCGCCGAGTGTCCTACATATCCACGATgacgacgaggacgatgaGGATGAGGGAGACATGGAGGAGAACAGCCACGAAACCCCCCTGGAAGACGACGATGGCGATGATGAGCGCGAGGAAAACAGTCGGAGTCGCAGCAAGACAACGAAAAAGTCACGCAAAACCAAGTCAAAGAGGAACAAGCGTCTCTCCGACGACGATGAGTTCATCATCAGCAGCGGCTGCGAAAGTGAGCCAGAACGGGAACGCAAAAAGGATCATCATAAGGATCATCCAGCAACAGTTCCTCTTCCGCCCCTAAGCACTGCTCCCTCGACGAGTAGGGCAGCTGCCACAGCCACATCGCTATCCAATCCGGCCGAAAATCATTCCAGCTCTGCTTCAAATTCCATATCCGGCAGCACCCCCACCAAGTCTAAGAAGAACCGGATCACAGTGCTAAGCGATGTGCCGCTCAACATGAACGAGTACCTCGACCTAATGGGAAACATTGTGGCCTCCAGTCGGATTGGGGCAGCTCGCCCCTTTGCAGCTGTGGCTCCTATTCCATTGGTCAAGGTGGAGAAGGAAGAGCCCTTGGATGAGTACGACAATGAggcggagcagcagcagatggAGCAGAAGCCCAGCCTGGAGCATGGCACCACCAGCGTAATACGAATGGCCAGCACATCGTTGGCGGCAACAGCCGTTTCCGCCGAGGACCTCACCCAGCCGCCGCCCATGAAAGTGGAAGTGGATCCCAATACCAAGCTTCTGCCCCAGCGTTTCTCTACTCCTGCGCAGCAGCTGCGCGGACCCAAGAAATTAGTCATTAAACCAAAGGCGACGGCAGCAGCTACGGCTACAGCGACGAAAAAGACTGACACCCCATCttcctccagcagcagcaacagcagtaacagcagcagcaacccaACCATATCAAAGGACTTTGTGCAGGTGAAGAGTGAAAACTTGGAGGGTCCAATGGGCAGTAGCATATTGGAGAAGCACCTGACCACCACCCACAGCAGCCGCAAACTTCTGCATCATTCGGCGGCGAATGACGACGATGCGAGGGTGTTGCTGGAGTTTGCCAACTCCAAGCAGCCGCCTCCGTTGACTGCCGCTGGCACCACGTTTGTGGTGAATGCCAGTACGGGATTCCCTTCGGCAGGATCCGTTTTTGCCAGCACCTCCAAAGCAACGGCTATAAGCAAACCCGAAGACGAATACATCCTCCCAGACAACAACTTGGATGTGGATGAGATTGTGATATCCTCGTCATCTTCCTACGCTTCCTCTGCGGCGCAGGTGCAGGCCACGCTGCAACCGCCGGAATTCAATTTCTTGTACCACCAGCAgaacaccaccaccaccacggtCACCACCGGAGCATACTTCAACTCCTTCTCCAAACAGCAGAATCTCCAACAGCAACACGGAGTTAGCGATGCCACTAATGCAGCCACTCTGGCCTCCTCTTCGAGTAATTCCATGGACCACGATTCCATGAACGCCACATTCCGCGTGGCTAAGACTCAATCATTGCAGTCCTGGTATCAGCAGGATCACGAACAGGATGCACACAATCAAGGTGTTGTGGGAGCCGGTTCTGGTGCAGCTTCTGGCAATAATCAGGGTCATGATGTGGTGTCCCAGTCCACGAACTTCAACGCTGCCCTGGCTTCTGTCGACTGCTGTAGTGTGGCGCTGGACGGCGATGCAAAATACTTGGATCTGGACGCGTGCAAGCGAGAGCAGCTGAGTGGCAGCAACTTACCCTCGGCCTCGGCGTCCACTTCGACCACATCGTCATCATTTGCGGGAGCAGGCACGGAGAGCAGCTTGGTGGGTGGTTTGAACATTCGCACCGATGAGAAGATGCCTGCCAAGGGTGAAATCTCAGAGCAGGAGAGCAACTGCGATGTCGAAAACTCTTGGAGTGAATCGGTATACGGAGATATTTCACAGCGATACTTTAGGAATCAGTTTTCTGGAGGCTACAATTCAGATTGGCGCCAGGATTACTTTCCTACTCAGGATATAAACGGTCAACCACGAGAGCAAAAACATTTCGATTTTAATGCGCTTGACGATGAGGCCTCATCCAGCTCTAGGAAGAGCCATCTACTGGATGATGCGCCTACGGCGGGCATCGCACCTTCCAACTGCACTTCCACATCTTCGGCTTTGCTGGCAGGTCCACCAATAGCCTCCACTTCCCGGGCTGCTGCCGAGGCAGAAGCCGCTGCCATGGCAGTCGCCCAAAGAAAGCAGAATCGTCGTAAGCTCTACAAATGCCCCAATTGCGACGCTATCTTCGAGAAGTTAAAGGACCGGAATGCACACATGATTGGAGAGCATAACTATGTCCGTCAGAACCGCAGGCTCATTTGCACCCAGGTGCCCGGTTCCGAGATGCTCCCACCGCAGCAGCAAACAATGATCATACCGCCAGCCGAGGGGGTCGCCCTCCAAGAGGACTCCAAAGACGGAATTGTGAAAATCAAGCAAGAACAATGCCAAGACAAGACGGAGGTAGATCAAATGCACTCCAATTCCGAGCTGTTGACAGATGTCAAGGACTCGGAACTGCTCGGAATCGGGGATGCCGATGGGGACGAGGAGGGTGAAGCCGATTTCAAACCACCTAGTCAACTGGATGAGAAGATCGTATTACCACCGCTGGCCATGACGACTCCAGCTGCTAAGCTAGCAGCGCTTTATCGCATGCTTATCGCCTACAATGAGTCCAAGCTGGGCCAAGAGCGAAACAACCTAAGCGAGCTGGAACAGAAGGCCATGGAAAAGTCAATCTTTCTCTGCTATGTCTGCCGAACCGACTTCCCATCGGTGAAGCTGTACGATGCTCATCTTACCGAGCATCCGGCCGAATGCTTTACCTGCGGCAAGAAGTTCTATCGCTGGAAGAACTTTTCCCTCCACCTGAAACGTCATCTCGGTTGGAAGGAATTTGGCTGCTATGTTTGCGATAAGAAATTCGTTGTACGCAGCGCCCTGGTCGAGCACATGCGGATGCATACGGGCCAAACGCCACTCAAGTGTAAGATATGCGGCAAGAAGTTTAAACGGTACTCGAATCTAACACAGCACCGAAAAAGGCACACCAAGATGATACTGCGCAAGAAGGAGTATGTGTGCCACTGCGGCGAAGTGCTGCCCTCAAAGGCACGATTCCTGTGGCACAAGGAGACCCACGATCTAAAGCCAAAGTGCTGTCCATATTGCTGCGATCGATTTGTGCATGCTAATTCGCTACGACGCCACATCCGGCTGGCACACTCGGAGAAATTCGATTATTCCGAGCCCATAGAGTGCCCAATGTGCAAGCAGACCTTTGCCAAAACCTCGATTAAAGCCCACATGGCGACGCATTCGACGGATCCGCAGTACGACTGCACCATCTGCAACAAGAGCTTCTCCACCAAGTGGAACCTCAAGATCCACTCATGGGTGCATGCCAATCGCACGGCCAAACCTTTCAAGTGCGAGTACTGCCCGAAGGCGTTTGTGCGCGAGCTGGACTTCAAGAACCACATCAACGCGCACAAGCAGATCAAACCGTACACGTGCGAGTACTGCGGCTGTAAGTTCATCCGCAAGTACAACTACATGCGACATCGTCGCGAGCACCACGGAACGAAGAAGTTTACATGCGACCAGTGCGACAAAACCTTCCACCGGCACTACTATCTCGTTGAGCACCGGCGCATGCATACCGGCGAGCGACCCTTCACCTGCACCATATGTGGCAAGAGCTCCACCACCAAGACCAACCACAACAAGCATCTGAAGATCCACCACTCGCGCGATCCCTTTACTGTCGAGGTTTAA
Protein Sequence: MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGSGSGGSALAAAMLAGAGSGSSGSAANTAESIAIDDKTAITPLNVEVKPVVAPKSISAGASAVQTPPQSQLQSQPQPQAPPPPLSSTLPAPASTTSTSATAANSSKSPNSNKLSNPPIKAMKCSPPPTEARSSTSAHPTTSMSSSLYQPTLVAPDYRFNQQQQPQQQPMFGRGSNAPTATLVIPQVSQQHFLTTNPQQQAHFSHQQQPPQQQQQQQHQQQPALKYTYATALPPPPPLQLFTQQQPMQQPATSSQTNSPPHAKPPPAYGAAISQIRSQHNQNKQQPQQQQQLQPQQPHLTVHHNHNHNLTLTPPTAGKQLVSGKAHSEVFLNPPPPPSQTQGQQNLGHQQNQNLSTHASPQLLGTASSNRLLQQHQPLGMPIYVSGSGASSTHSSSSSSHSLPMNASSASTCASIRGHRQTNSPFGALLNAAAAVACPSPASSSASSSVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEDEGDMEENSHETPLEDDDGDDEREENSRSRSKTTKKSRKTKSKRNKRLSDDDEFIISSGCESEPERERKKDHHKDHPATVPLPPLSTAPSTSRAAATATSLSNPAENHSSSASNSISGSTPTKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGAARPFAAVAPIPLVKVEKEEPLDEYDNEAEQQQMEQKPSLEHGTTSVIRMASTSLAATAVSAEDLTQPPPMKVEVDPNTKLLPQRFSTPAQQLRGPKKLVIKPKATAAATATATKKTDTPSSSSSSNSSNSSSNPTISKDFVQVKSENLEGPMGSSILEKHLTTTHSSRKLLHHSAANDDDARVLLEFANSKQPPPLTAAGTTFVVNASTGFPSAGSVFASTSKATAISKPEDEYILPDNNLDVDEIVISSSSSYASSAAQVQATLQPPEFNFLYHQQNTTTTTVTTGAYFNSFSKQQNLQQQHGVSDATNAATLASSSSNSMDHDSMNATFRVAKTQSLQSWYQQDHEQDAHNQGVVGAGSGAASGNNQGHDVVSQSTNFNAALASVDCCSVALDGDAKYLDLDACKREQLSGSNLPSASASTSTTSSSFAGAGTESSLVGGLNIRTDEKMPAKGEISEQESNCDVENSWSESVYGDISQRYFRNQFSGGYNSDWRQDYFPTQDINGQPREQKHFDFNALDDEASSSSRKSHLLDDAPTAGIAPSNCTSTSSALLAGPPIASTSRAAAEAEAAAMAVAQRKQNRRKLYKCPNCDAIFEKLKDRNAHMIGEHNYVRQNRRLICTQVPGSEMLPPQQQTMIIPPAEGVALQEDSKDGIVKIKQEQCQDKTEVDQMHSNSELLTDVKDSELLGIGDADGDEEGEADFKPPSQLDEKIVLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMILRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSEKFDYSEPIECPMCKQTFAKTSIKAHMATHSTDPQYDCTICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKTFHRHYYLVEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00580145;
90% Identity: iTF_00615074;
80% Identity: -