Basic Information

Insect: Drosophila merina
Gene Symbol: ZNF574
Assembly: GCA_035047645.1
Location: JAWNPH010000089.1:9205057-9207201[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.067 6.1 7.7 0.2 2 23 315 337 314 337 0.95

2 10 0.49 45 5.0 0.3 6 23 347 364 347 364 0.98

3 10 1.6e-05 0.0015 19.1 0.5 1 23 370 392 370 392 0.98

4 10 0.00021 0.019 15.6 0.7 1 20 407 426 407 430 0.87

5 10 9.1e-05 0.0083 16.7 0.9 1 23 438 461 438 461 0.97

6 10 3.2e-05 0.0029 18.2 1.6 3 23 469 490 467 490 0.92

7 10 0.001 0.095 13.4 0.4 2 23 502 524 501 524 0.97

8 10 0.00053 0.049 14.3 7.1 1 23 531 554 531 554 0.93

9 10 6.7e-07 6.1e-05 23.5 0.8 1 23 560 582 560 582 0.98

10 10 6.6e-05 0.006 17.2 1.3 1 23 588 611 588 611 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.067	6.1	7.7	0.2	2	23	315	337	314	337	0.95
2	10	0.49	45	5.0	0.3	6	23	347	364	347	364	0.98
3	10	1.6e-05	0.0015	19.1	0.5	1	23	370	392	370	392	0.98
4	10	0.00021	0.019	15.6	0.7	1	20	407	426	407	430	0.87
5	10	9.1e-05	0.0083	16.7	0.9	1	23	438	461	438	461	0.97
6	10	3.2e-05	0.0029	18.2	1.6	3	23	469	490	467	490	0.92
7	10	0.001	0.095	13.4	0.4	2	23	502	524	501	524	0.97
8	10	0.00053	0.049	14.3	7.1	1	23	531	554	531	554	0.93
9	10	6.7e-07	6.1e-05	23.5	0.8	1	23	560	582	560	582	0.98
10	10	6.6e-05	0.006	17.2	1.3	1	23	588	611	588	611	0.97

Sequence Information

Coding Sequence: ATGACACCCTGCGTCCTCTGTCAGGACGACACCGACGCCGCCTACAGCCTGCATTCTGAAGAGGGCGTCCGGCTAAACATAAGGGACATCATTGCCAAGCACTTTTCATTTTTCGAACTACCAAGTACAGGCAGCAATGTGGAGGCTATCTGCCGGGAGTGCTGGACATGTGTCACCAGCTTCGACGAACTCTATCAGAGGGTATTTAAGTTGCAccaggtgggtggtggtggtggtgactTAAAAAGCGTTCCCATCGAATTTTGTGGAGAAGCGGAATCCATCAATCCACTGTTTACCATTGAGGTAGATGCCCTGGCCGAGGGATTCTTTGCTCCCAATGAGGTGAAAGTTGAGGTAAACGAACTGGAGCCCCTCCCAAAACTAGAACTCCTGGAAGATCCGGTTGATACGGAATCCAAGTCAAGCAACAAAAGGGCCGGATCTCTATCAGAAGGCCCCTCTCAGCCCAAGCGTCGGATCAAAAACGAGCAGCCAGTGGACAGTGAATCGGATGTTCCACTGTCCAAGTATCTAGAGACCGCCCCACTAAGAAGAAGTACGAGGCGCGGCCGCCCGCCTAAGGCGAAACCAGAACCCTGCCCTTCCTCTCCCAAAAGGGAGTACCTTTCCGAAGAAGATCCTGATAACGATACAAATGACGGAGAATTTGAACTGGCGGAGGCCGTTCTGGGGACCGATGACAGCGCTAGTACCTCCAGCGATAGCAGTGGCGAAGATTCGGACAATAGCCTGCCCGATATTGAACCAGAGGAACGGTATGCTGAGATTCCTAAGCGGGTTGTGGTCAAACCCAAGAAGTATAGAAAACGAGAGAAGCCACTAGTTCCGCCTGTACGTATGAGTCGGGCGGAGATCGAGAGGCGAAAGCATCAGCAGGAGGAGTATGATGAGGTTATTCTCGGATTTTTCAAGAAACTACCCTGTTCTATTTGCAATCTGCTGGTGCAGAATTTTGCTGATATGCGGCGACATCAGCGTATGTCCCATGACATTGATTCGGGTTATATTGAGTGCTGCGGAAAAAAGTTTCACCTGCGAAAGGGGCTGGCGGAACATGTGCTGGTGCACAAGAATCCAGATCACTTTATGTGCTCGCAATGCGGTCGGGTGTTCCAGGACTCGCGTACATTGGAAGTGCACGAGCAGACCCATATAAATCCGGAGGTGAAGACGGAACTCAAGGATAAGCCAGTTTATCAGTGCGATAAATGCCCGAAGAGTTTCACAACAAAAGCCGCCATTGAGTACCACAACGTCTCGAAACATGTGCCCAAGTCAGAGTTCAAGTATTCCTGCCCAGAGTGCAAAAAGAAaaTTCCCACTGAACGGAAATTGAAGGAACACATGCGGTACATGCACGATCCCGAAACGGCGATTATCTGCGACAAGTGCGGCAAGACACTGCGCTCCCAAACGAATCTCAAGAAGCACCACGAGCTGGAACATTCCGAAGAACCGCGCCGCAAACCCGATCCCGTTCAATGCGAGATCTGCGGCACCTGGCTGCGCCACCTTTCCGGACTGAAACAGCATATGAACACGGTGCACGAGCCGCCGGGCGGTGAACACCGCTGTCACATTTGCAACAAGACCTCAACTAATTCTCGAGCCCTTAAGCGACACATTTACCACAATCACCTCTGCGAACGCAAATTTAAGTGCGGTATGTGCGATAAGGCTTTCAAGCGCCCACAGGATTTAAGAGAACACACGTCCACGCACACAGGCGAGGTGCTCTACACCTGCCCCAACTGCCCTATGACCTTCTTTTCAAACGCTAACATGTACAAGCATCGCCAGCGACTCCACCGCGCCGAATGGGAGGCGGACCGCAAGAAGCCGCTGCCGCCGAACATAATGAAAATTTCTCAGGGCGCTACAACGGCGATGAAGAAGCGCCAGGCCAGCAGCGGCATGTTCCCACAGTCGGAACAGAAGCAATAG
Protein Sequence: MTPCVLCQDDTDAAYSLHSEEGVRLNIRDIIAKHFSFFELPSTGSNVEAICRECWTCVTSFDELYQRVFKLHQVGGGGGDLKSVPIEFCGEAESINPLFTIEVDALAEGFFAPNEVKVEVNELEPLPKLELLEDPVDTESKSSNKRAGSLSEGPSQPKRRIKNEQPVDSESDVPLSKYLETAPLRRSTRRGRPPKAKPEPCPSSPKREYLSEEDPDNDTNDGEFELAEAVLGTDDSASTSSDSSGEDSDNSLPDIEPEERYAEIPKRVVVKPKKYRKREKPLVPPVRMSRAEIERRKHQQEEYDEVILGFFKKLPCSICNLLVQNFADMRRHQRMSHDIDSGYIECCGKKFHLRKGLAEHVLVHKNPDHFMCSQCGRVFQDSRTLEVHEQTHINPEVKTELKDKPVYQCDKCPKSFTTKAAIEYHNVSKHVPKSEFKYSCPECKKKIPTERKLKEHMRYMHDPETAIICDKCGKTLRSQTNLKKHHELEHSEEPRRKPDPVQCEICGTWLRHLSGLKQHMNTVHEPPGGEHRCHICNKTSTNSRALKRHIYHNHLCERKFKCGMCDKAFKRPQDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKISQGATTAMKKRQASSGMFPQSEQKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00566243; iTF_00488171; iTF_00539115; iTF_00615699; iTF_00504150; iTF_00615064; iTF_00481698; iTF_00550410; iTF_00477499; iTF_00476096; iTF_00580118;
90% Identity: iTF_00481698; iTF_00615699; iTF_00615064; iTF_00504150; iTF_00477499; iTF_00550410; iTF_00476096;
80% Identity: -