Basic Information

Insect: Drosophila pseudoananassae
Gene Symbol: Znf574
Assembly: GCA_018153035.1
Location: JAECXR010000001.1:11970200-11972323[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.088 6.2 7.3 0.2 2 23 309 331 308 331 0.95

2 10 0.35 25 5.4 0.2 6 23 341 358 341 358 0.98

3 10 5.4e-06 0.00038 20.6 0.1 1 23 364 386 364 386 0.98

4 10 5.6e-05 0.0039 17.4 0.8 1 23 401 424 401 424 0.93

5 10 2.5e-05 0.0017 18.5 0.5 1 23 432 455 432 455 0.97

6 10 3.1e-05 0.0022 18.2 1.6 3 23 463 484 461 484 0.92

7 10 0.001 0.071 13.4 0.4 2 23 496 518 495 518 0.97

8 10 0.00051 0.036 14.3 7.1 1 23 525 548 525 548 0.93

9 10 6.4e-07 4.5e-05 23.5 0.8 1 23 554 576 554 576 0.98

10 10 6.3e-05 0.0045 17.2 1.3 1 23 582 605 582 605 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.088	6.2	7.3	0.2	2	23	309	331	308	331	0.95
2	10	0.35	25	5.4	0.2	6	23	341	358	341	358	0.98
3	10	5.4e-06	0.00038	20.6	0.1	1	23	364	386	364	386	0.98
4	10	5.6e-05	0.0039	17.4	0.8	1	23	401	424	401	424	0.93
5	10	2.5e-05	0.0017	18.5	0.5	1	23	432	455	432	455	0.97
6	10	3.1e-05	0.0022	18.2	1.6	3	23	463	484	461	484	0.92
7	10	0.001	0.071	13.4	0.4	2	23	496	518	495	518	0.97
8	10	0.00051	0.036	14.3	7.1	1	23	525	548	525	548	0.93
9	10	6.4e-07	4.5e-05	23.5	0.8	1	23	554	576	554	576	0.98
10	10	6.3e-05	0.0045	17.2	1.3	1	23	582	605	582	605	0.97

Sequence Information

Coding Sequence: ATGACAGCTTGCGTCTTATGCCAGGATAGCACCGACGCCGTCTTCACCCTATGTTGCGAAGAGGGCGTCCGGCTTAACATAAGGGACATCATATCCAAGCACTTTTCATTTTTTGAATTACCTGGTACAGCCAGCGATGTGGAGGCTATTTGTCGGCCGTGCTGGACATGCGTCACCAGCTTCGACGAGCTGTACCAAAAGGTATTTAAGCTGCATCAGATGGGTCTCGACGCGAAGAGCGTTCCCATCGTGTTTTGTGGGGAATCGGAGTCTATCAATCCGCTGTTCACCCTGGAAGTGGATGCCCTAGCCGAGGGATTCTTCGCTCCCAACGAGGTGAAAGTGGAGGTGAACGAATTGGAACCCCTCCCAAAACTGGAACTCCTCGAAGACCCCGTTGATACAGAATCCAAGTCAGGCAACAAGCGGTCCAGATCTCAAGCGGAGTGCCCCTCACAACCAAAGCGTCGCATAAAAAACGAACAGCCCGTGGACAGTGAATCGGATGTTCCATTATCGGTGTATCTGGAGACAGCTCCGGTCAGAAGAAGTGCTAGGCGTGGACGCCCACCCAAGGCAAAACCACCACCATCCCCTGCCTCGCCCAAAAAGGAGTACCTTTCGGAAGAAGAGCCTGAGAACGACGCAGAATTTGAGCCCCCGGAAGCTGTTTTGGGTACCGATGATAGTAGCACTTCCACCAGCGACACCAGTGGCGAAGATTCGGACAACAGCCTGCCAGACATTGAGCCAGAGGAACGGTATGCTGAGATTCCCAAGCGGGTTGTAGTCAAACCCAAGAAGTATAGAAAACGTGAAAAGCCTCTTGTTCCGCCTGTACGAATGAGTCGTGAGGAGATCGAGCGACGAAAGCAGCAACAGGACGAGTACGATGAGGTTATTCTGGGATTTTTCAAGAAGCTTCCCTGCTCCATTTGCAATCTTCTTGTGCAGAATTTTGGCGACATGCGGCGACATCTGCGCATGTCCCACGACATCGAGTCAGGATATATCGAGTGCTGCGGGAGAAAGTTTCACGTTCGTAAAGGGCTGGCGGAACATGTGATGGTACACAGGAACCCAGATCACTTTATGTGCTCGCAGTGCGGGCGGGTGTTCCCGGACTCGCGTGCTTTGGAAGTACACGAGCAGACGCACATAAATCCCGAGGTGAAAAAGGAACCCAAGGACAAACCCATTTACCAGTGCGATAAGTGCCCAAAGAGTTTTACCACCAAGGCGGCCATCGAGTACCACAGAGTCTCCAAGCATGTGCCCAAGTCCGAGTTCAAGTATTCCTGTCCAGAGTGCAACAAGAAAATACCCACTGCTCGAAAATTAAAGGAGCACATGCGGTACATGCACGACCCCGAATCGGCCATCATCTGCGATAAGTGCGGCAAGACACTGCGTTCACAAACGAATCTCAAGAAACACCACGAGTTGGAACATTCCGACGAACCGCGCCGTAAGCCCGATCCCGTGCAGTGCGAGATTTGTGGCACCTGGCTGCGGCATCTCTCTGGACTGAAACAGCATATGAACACGGTCCACGAGCCGCCGGGTGGCGAGCACCGTTGCCATATATGCAACAAGACCTCCACCAATTCCAGAGCCCTCAAGAGGCACATCTACCACAACCACCTCTGCGAGCGCAAGTTCAAGTGCGGTATGTGTGACAAGGCCTTCAAGCGCCCACAGGATTTAAGGGAACACACTTCCACGCACACCGGTGAGGTGCTTTACACCTGTCCCAACTGCCCCATGACCTTCTTTTCCAACGCTAACATGTACAAACATCGCCAACGGCTACACCGTGCCGAATGGGAGGCGGACCGGAAGAAACCGCTGCCGCCGAACATAATGAAAATTTCACAGGGCGCTACCACGGCGATGAAGAAGCGCCAGACCAGCAGCGGCGTGTTCCCACAGTCGGAACAGAAGCAATAG
Protein Sequence: MTACVLCQDSTDAVFTLCCEEGVRLNIRDIISKHFSFFELPGTASDVEAICRPCWTCVTSFDELYQKVFKLHQMGLDAKSVPIVFCGESESINPLFTLEVDALAEGFFAPNEVKVEVNELEPLPKLELLEDPVDTESKSGNKRSRSQAECPSQPKRRIKNEQPVDSESDVPLSVYLETAPVRRSARRGRPPKAKPPPSPASPKKEYLSEEEPENDAEFEPPEAVLGTDDSSTSTSDTSGEDSDNSLPDIEPEERYAEIPKRVVVKPKKYRKREKPLVPPVRMSREEIERRKQQQDEYDEVILGFFKKLPCSICNLLVQNFGDMRRHLRMSHDIESGYIECCGRKFHVRKGLAEHVMVHRNPDHFMCSQCGRVFPDSRALEVHEQTHINPEVKKEPKDKPIYQCDKCPKSFTTKAAIEYHRVSKHVPKSEFKYSCPECNKKIPTARKLKEHMRYMHDPESAIICDKCGKTLRSQTNLKKHHELEHSDEPRRKPDPVQCEICGTWLRHLSGLKQHMNTVHEPPGGEHRCHICNKTSTNSRALKRHIYHNHLCERKFKCGMCDKAFKRPQDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKISQGATTAMKKRQTSSGVFPQSEQKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00546127;
90% Identity: iTF_00566243; iTF_00488171; iTF_00539115;
80% Identity: -