Basic Information

Insect: Drosophila merina
Gene Symbol: -
Assembly: GCA_035047645.1
Location: JAWNPH010000089.1:14683067-14686515[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.052 4.7 8.1 3.0 3 23 317 338 315 338 0.96

2 18 0.24 22 5.9 0.4 1 23 345 370 345 370 0.91

3 18 0.038 3.5 8.5 2.1 2 23 381 402 381 402 0.93

4 18 0.0098 0.9 10.3 0.5 3 23 443 464 442 464 0.95

5 18 0.0022 0.2 12.4 0.5 3 23 472 492 470 492 0.95

6 18 0.093 8.5 7.3 0.1 1 23 500 523 500 523 0.96

7 18 0.00027 0.025 15.3 0.3 2 23 528 549 527 549 0.97

8 18 2.1 1.9e+02 3.0 0.1 1 20 557 576 557 578 0.83

9 18 0.0007 0.064 14.0 1.0 1 23 597 621 597 621 0.91

10 18 0.048 4.4 8.2 1.8 3 21 628 646 628 647 0.90

11 18 0.0023 0.21 12.3 0.5 1 23 666 691 666 691 0.96

12 18 0.2 19 6.2 1.7 2 23 709 731 708 731 0.94

13 18 0.002 0.18 12.5 0.3 2 23 737 759 736 759 0.93

14 18 0.008 0.73 10.6 0.2 2 23 763 785 762 785 0.96

15 18 4.2e-05 0.0038 17.8 2.0 1 23 791 813 791 813 0.97

16 18 0.0041 0.38 11.5 1.0 1 23 817 840 817 840 0.94

17 18 5.8e-06 0.00053 20.5 1.4 1 23 846 869 846 869 0.97

18 18 9.6e-05 0.0087 16.7 0.2 4 23 876 901 873 901 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.052	4.7	8.1	3.0	3	23	317	338	315	338	0.96
2	18	0.24	22	5.9	0.4	1	23	345	370	345	370	0.91
3	18	0.038	3.5	8.5	2.1	2	23	381	402	381	402	0.93
4	18	0.0098	0.9	10.3	0.5	3	23	443	464	442	464	0.95
5	18	0.0022	0.2	12.4	0.5	3	23	472	492	470	492	0.95
6	18	0.093	8.5	7.3	0.1	1	23	500	523	500	523	0.96
7	18	0.00027	0.025	15.3	0.3	2	23	528	549	527	549	0.97
8	18	2.1	1.9e+02	3.0	0.1	1	20	557	576	557	578	0.83
9	18	0.0007	0.064	14.0	1.0	1	23	597	621	597	621	0.91
10	18	0.048	4.4	8.2	1.8	3	21	628	646	628	647	0.90
11	18	0.0023	0.21	12.3	0.5	1	23	666	691	666	691	0.96
12	18	0.2	19	6.2	1.7	2	23	709	731	708	731	0.94
13	18	0.002	0.18	12.5	0.3	2	23	737	759	736	759	0.93
14	18	0.008	0.73	10.6	0.2	2	23	763	785	762	785	0.96
15	18	4.2e-05	0.0038	17.8	2.0	1	23	791	813	791	813	0.97
16	18	0.0041	0.38	11.5	1.0	1	23	817	840	817	840	0.94
17	18	5.8e-06	0.00053	20.5	1.4	1	23	846	869	846	869	0.97
18	18	9.6e-05	0.0087	16.7	0.2	4	23	876	901	873	901	0.83

Sequence Information

Coding Sequence: ATGTCGGAAAACCAggaaaaacaaagctgcctgcattgtagagtattCAATCCGAAATTCCAGTACCAGGAGATATTTGATGAGTTTGGCACCGAGTTGGGCCTGCAATCCTTGTTGGCAAAGCATTTTGATTTCACGGTGACACCGGATTCCAATAAATCACAGCTGCTTTGTGAGATTTGCGTCAACAGTTTAATCCGTCTCTTTGACATCGATGAGCTGCAGCGGGAACAGGATGCGGCGAAGGATAACGTCAAGTCGACTGCTCCGGCACCTCAAGCTGTTATCCCAGAATGCAGTGCTTCGTCCAAACCATCCTTGCAGCCTCCTCCAAAACAGGCTGCTCTACAAAATACCAAACCCGTAAAAACTAGACCAGTTTCTCTTAAAGAAGGAACCTGTACTCTCGTTAGGAAGGAATCACCACCACCTCAGATATCTCCTACTACTTCTAAGGAATTTGATAAACTCAAGGAGCAGGCCATATCCGCTCCTTCCGTCAAGTCACAATCTAAAAGAATCTCCAAAGAATCGGATCAGGATCAGATCAGTCGTCTTATATGCAACATCCTAAACGAGGATGAAACCATCGTTGAGGAGGTAGCTGCTCCACAGCCAGAGGAACCCGAGAAGCAGGAGGAAATAGTTCTGCTGGACAGTGAGTCCATAGCCGATCCTGATATAGACCAGGAAGAATACATTTACGACCATGAAGATATCTTGGACCCGGTTTTGGAGAACCTAAAGCTAAAGGCAGAGACTCGACAGAAGGTGCAAGCGGAGGATAGCCAGAGCGAAGGAGAAAACGATGAAAGTGAATCCAGCAACGTGGTGATCTTCAACTTTGTTGAGATTAAAGAACAAGACGACATTAGTAACATTTTCGACTACCTTTCTACGGTGGTAAAAACCAGCTTTGAAAAACTCTCTTTTGAGTGGAGTACAGATTGCAAGCACTGCTCTCAAAAGTTTCAGAACTTCAAGGCTCTATTAGGTCACATGCTAAAGTCTCATAAATCTCGGGGTAATGTCTACAAGTGTCCTTTCAAAGACTGCAGCAAGGAGCTAAAAGGATCCAAATTTCTGGCCATGCATCTGGTTCTCATGCATGCCAATCTAGTAGACATTCCAATCTATGGCAGCTGTCCGGAGTGCAAATTGACATTTTCAAACATTTTGCAGTACAACAAACACTCTTGTGCCCATGTTATCAAAAAGAAACGAGGCGTTCGTCTTTTTTGCGAAATGTGTGCCCAATATTTCCCTTCCTGGAAGCGGTTCAACTTTCATAATCAATTTCATCTGGAGAAACACCGTCCCCGTAACTGCTTCATCTGTGATTATTCTAGCACTAATATTGACGAACTCTTCCAGCACTTGAACTATTTCCACGAGCCAGAGGGTACTCTTTTCTGTGATCTTTGTGATCGCACATTCCGAGACCCTGAGGTTTTTACAGACCATAACAAATCGCATGCCAATGTTAGTAGCACCACCTTTTCCTGCGGCGAGTGCATGGCCATGTTTGAGTCGCGTGGTCGGTTGAACGGACACATGAGAGCTATGCATGGCAGCGCTATAAGCTGCGAAATGTGCTCCCGCGAGTTCGCCACCGAGGCTACCTACAACGTCCACATGAAGAAGCACTTGATCATCGAAAAGGACATCTATGTGTGCAGCAAGTGCGGGCTGTTGAGCGAAAAACAGGAGACTATGCTAGCACATGTACACAATCAGGAGTCAGCCTGTTTTGAAGCAAAGTTTCTTACGGAACTGCTTCGAGATGCCTATGCTTGCGAACACTGCTCGCTCTACTTCAAGGAAAAGGCTGACCTGCGTAGGCATCGGGAAACCGGAGTACACGAGAACAGACTGTACTGGTGTCAACCGTGTGGGAAGGAATTCTCACATATGAAACTCTACCGCCATCATATTCGTAATTTTCAACAAATCAAAGGGGATTCCACACACCGCAAGCTGGATATTTGTGTTTTCTACATGTGCGATCAGGAGGGTTGTTCCGAATCTTATGCCAATTGGAATTCTTTATACACGCACAAGCGACGCACCCATGAATCTGCACCCAAGCAACCTGATAAAACTACAAAATCAGAACAAGAGTGGGTGTGCCAGTTTTGTTTGAAGCAGTGCCGCTCTAAGATGTCCTTGTCAGTTCATGTGGCAAGAAGTCACAATAATGACAATGTTACTTGTCCTTTGTGTAATGCGTCTTATAAGAACCAGGAAGCTTTGGACAAGCACCATGCCTACTGGCACGAGCCTATTGAATGTCCCCAGTGCTTTAAAATCGTAAAAAACAGGCGCAACTATGATACTCATTTAAATGTCGTACATTCGAATACAAAGCGTTATGCCTGCAGTGTGTGCCAAAAGGGTTTCTACCACAAAAGCGAAATGGAATCACATCAAAGGCTCCATGGCCAATCGTACAACTGCGACCAGTGCAGCTTTACCACCAGGAACAAGAAGTCCCTGTCCGTGCACATCCTTGGCCAGCATTACAAACGATTTGCTTTTGAATGCAAGATGTGCAATAAGCGCTTCGGACGCCGGCAAGGCCTCAACACCCACATGCAACGAGCTCACGGTTCAAAGTTCATGTGCCGGGACTATTTTGAGGGCGGTTGTGGGCGAAATTTCATCAACAGCTCCCAGTTGAATGTTCACGTGCGGAAGGTGCACAATGGCACCATTTTCCTGACcgaggaagaggaggaggagttcaTCAGCGATGGGCCATCATCGTCCAAGAAACGCTGCTTTCGCATCGATGATGATACCAATATTGAGTTCATAGAAGATTCAGAAACTATTCCAGATGAAATAGAAATGGTGGATGAAATCGATGAGGATGATTACATTAACGAAGATTTAGACGACAGTTCCGTTTCCAAAAATTAA
Protein Sequence: MSENQEKQSCLHCRVFNPKFQYQEIFDEFGTELGLQSLLAKHFDFTVTPDSNKSQLLCEICVNSLIRLFDIDELQREQDAAKDNVKSTAPAPQAVIPECSASSKPSLQPPPKQAALQNTKPVKTRPVSLKEGTCTLVRKESPPPQISPTTSKEFDKLKEQAISAPSVKSQSKRISKESDQDQISRLICNILNEDETIVEEVAAPQPEEPEKQEEIVLLDSESIADPDIDQEEYIYDHEDILDPVLENLKLKAETRQKVQAEDSQSEGENDESESSNVVIFNFVEIKEQDDISNIFDYLSTVVKTSFEKLSFEWSTDCKHCSQKFQNFKALLGHMLKSHKSRGNVYKCPFKDCSKELKGSKFLAMHLVLMHANLVDIPIYGSCPECKLTFSNILQYNKHSCAHVIKKKRGVRLFCEMCAQYFPSWKRFNFHNQFHLEKHRPRNCFICDYSSTNIDELFQHLNYFHEPEGTLFCDLCDRTFRDPEVFTDHNKSHANVSSTTFSCGECMAMFESRGRLNGHMRAMHGSAISCEMCSREFATEATYNVHMKKHLIIEKDIYVCSKCGLLSEKQETMLAHVHNQESACFEAKFLTELLRDAYACEHCSLYFKEKADLRRHRETGVHENRLYWCQPCGKEFSHMKLYRHHIRNFQQIKGDSTHRKLDICVFYMCDQEGCSESYANWNSLYTHKRRTHESAPKQPDKTTKSEQEWVCQFCLKQCRSKMSLSVHVARSHNNDNVTCPLCNASYKNQEALDKHHAYWHEPIECPQCFKIVKNRRNYDTHLNVVHSNTKRYACSVCQKGFYHKSEMESHQRLHGQSYNCDQCSFTTRNKKSLSVHILGQHYKRFAFECKMCNKRFGRRQGLNTHMQRAHGSKFMCRDYFEGGCGRNFINSSQLNVHVRKVHNGTIFLTEEEEEEFISDGPSSSKKRCFRIDDDTNIEFIEDSETIPDEIEMVDEIDEDDYINEDLDDSSVSKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481678;
90% Identity: iTF_00504130;
80% Identity: -