Dmer014079.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila merina
Gene Symbol
-
Assembly
GCA_035047645.1
Location
JAWNPH010000059.1:23525835-23529046[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 6.6e-05 0.006 17.2 1.6 1 23 329 351 329 351 0.93
2 9 1.6e-08 1.5e-06 28.5 2.6 1 23 357 379 357 379 0.98
3 9 6.7e-06 0.00061 20.3 0.8 1 23 385 407 385 407 0.98
4 9 4.8e-06 0.00044 20.7 1.0 1 23 413 435 413 435 0.97
5 9 2.4e-05 0.0022 18.6 1.4 2 23 525 546 524 546 0.96
6 9 2.5e-09 2.3e-07 31.1 1.6 1 23 552 574 552 574 0.98
7 9 0.0031 0.28 11.9 0.9 3 23 582 602 580 602 0.97
8 9 8.3e-05 0.0076 16.9 0.9 1 23 608 630 608 630 0.99
9 9 0.014 1.2 9.9 1.1 1 23 637 661 637 661 0.95

Sequence Information

Coding Sequence
ATGGCCATCAATTTCTCGGCCTCTTTCGCGGCCTGCATAGCAGCCGGGCTCAAAGTGCCGCGCCAGATCATGTATTGTATCACGCAGGACACGGGCCAGCCGTACGTCCTCTACAAGGACTCGCAGGACGCCGAGCGCAACCCGGGCGCCATTGGAGCCAGCCCCGCACAGTGGGGCAGCGAAATGTACCCCAACATCCAACAGCAGGCCCAGCAGCACCTAAGtgctcagcagcagcagcaacagcaacagcagcagcagaacgcAGTGCAGGCGGCAGCCCAGGCGGCGGCCGCTGCGGCGGCGGCTGGTCAGCCCCAGAGTCCCCCCGGTGGGGGCCAGGAACCTCGCGACAACGGCAGCGGCGATGGCCGCCAGCAACAAGTGTCGCCCTCCTCCAGCCCTTACCCGTCGGTGCAGCAGCGAGGCAACGGTGGGGGCGAAGAAGATGCAATGAATCAGCTTGCTAACCAACAGAACTCTGCGCctaaccaaaaccaaagcagCAATGACCCCCAACACGCCGCACCCAACGCGGGAGAGCCAGGAAACCCACACGTGCAACAGAACGGGGGTGGCCCTCAGGGAGATCCTGGCAACGGCTTCCAGACTACGCCAGACTACTACGCTTCTCGCCATGCGCCGCCGCAGGGCGGGATGCTGGCTCCTCCCGGCTTTCCGCCTCTCCACTATCTCAACAAGCTGCCCATGGAGCAGCCTGGCGGTGGCGGAAGCGGAGGTGGCAGCGAGTCATACTCCATGCCAGAGCTTCTTCCAAGTCAGCAAAACGGTCAGCAGAACGCCGGTCCGGCCAATGCAAATGCCAATGAAGGCGCCGCAGCTACCaacggaggaggagcaggaggcgGTGCGAGCGGTGCCGGCGCCGGCGTGGGGACGGTCAGTGGTGTGGCGACTGGAGGGCGAACGGGCAATGGCCCAGGTCGTCCGCACAAGAACAAGCCGCACAGTGACCTACGGCTGTTCAAGTGCCTCACCTGCGGCAAGGACTTCAAGCAGAAAAGCACTCTGCTGCAGCACGACCGCATCCACACGGATGCACGGCCCTTTCCGTGCTCGGAGTGCGGCAAGCGCTTCCGCCAGCAGTCGCACCTAACGCAACACCTGCGCATCCACGCCAACGAAAAGCCCTTCACCTGCCCGTACTGTTCGCGCAGCTTCCGGCAGCGGGCCATTCTCAACCAGCATATACGCATCCATTCGGGTGAGAAGCCCTTCGCCTGCCCCGAGTGCGGCAAGCACTTTCGCCAGAAGGCCATCCTCAATCAGCATGTGCGCACCCACCAAGATGTCTCTCCCCATCTCATATTCAAAAACGGGCCACACCCGACGCTGTGGCCTTCGGACGTTCCCTTCCCGGGTGAGGACAATGACACTAAGGGGGACATTGCGGGAGGCACCGGCTACCACGACGATGATTCGCAGGGCACACCAGACGGCAGTGGCGGCATGCACTATCCCTCATACTTCAAGGACGGGAAAGGACAAAAGATCCTGCCCGAAGTGCTGCAGCACATAGGCGTGCGGCCTGCCAACATGCCGCTGTACGTTCGCTGTCCCATCTGCGACAAGGAATTCAAGCAGAAGACGACCCTCTTGCAACATGGTTGCATTCACATTGAGTCGCGGCCGTACCCTTGCCCGGAGTGCGGAAAACGTTTCCGCCAGCAGTCGCATCTCACGCAACACCTGCGCATCCACACCAATGAGAAACCATTCGGTTGCATGTACTGTCCTCGCTTCTTCCGCCAGCGAACTATACTTAACCAGCACTTGCGTATCCATACTGGCGAGAAGCCTTACAAGTGTGGCCAGTGCGGCAAGGACTTCCGGCAGAAGGCCATACTTGACCAGCACACGCGCACCCACCAGGTAGGCGACCGACCCTTCTGCTGCCCAATGCCCAACTGCCGACGGCGTTTTGCCACCGAGAACGAGGTGACCAAGCACATCGATAACCACATGAACCCCAATACCACAAAGGTCCGccgccagcagcaacaacagcatcagcagcagcaacaccagcaacagcaacagcaacagcagcagcagcagcaacagaataACAACAACACCGTGGCCCAGGTGGCCTCTGTGGCCAACCATTTAATGAATGATGCCAAGAACCTGGCAGCCCAGCAATtcctcaacaacaacaactcgGCGAGTGTGGACAACAAGGCCAACATCCTGCCGATGCGAAGTATAGCTGCCAATGCGGCAGCTGCCGCTGTCGTCCAACAATCGGTGGTGAAGAACGAGCTTTATTTCCCACAATGCTATGGGCCACCTTTCCAGCATCCGTTCCAGacacagcagcagccgcagcagcccAGCGTGGCGCACGCCAACGGTGGACCTACGCCGCCGGTAACGGTGACAGTGGCCAACTCGGTGGCTCCCGGAGTGGTGGTTCAGCAAAACGCGTCCGCCTCCGTGGTGGCCCAGTGA
Protein Sequence
MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNPGAIGASPAQWGSEMYPNIQQQAQQHLSAQQQQQQQQQQQNAVQAAAQAAAAAAAAGQPQSPPGGGQEPRDNGSGDGRQQQVSPSSSPYPSVQQRGNGGGEEDAMNQLANQQNSAPNQNQSSNDPQHAAPNAGEPGNPHVQQNGGGPQGDPGNGFQTTPDYYASRHAPPQGGMLAPPGFPPLHYLNKLPMEQPGGGGSGGGSESYSMPELLPSQQNGQQNAGPANANANEGAAATNGGGAGGGASGAGAGVGTVSGVATGGRTGNGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEDNDTKGDIAGGTGYHDDDSQGTPDGSGGMHYPSYFKDGKGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCGQCGKDFRQKAILDQHTRTHQVGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNTTKVRRQQQQQHQQQQHQQQQQQQQQQQQQNNNNTVAQVASVANHLMNDAKNLAAQQFLNNNNSASVDNKANILPMRSIAANAAAAAVVQQSVVKNELYFPQCYGPPFQHPFQTQQQPQQPSVAHANGGPTPPVTVTVANSVAPGVVVQQNASASVVAQ