Basic Information

Insect: Drosophila leontia
Gene Symbol: -
Assembly: GCA_008042735.1
Location: VNKB01008505.1:17278-20812[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 6.5e-05 0.0056 17.1 1.6 1 23 336 358 336 358 0.93

2 9 1.6e-08 1.4e-06 28.5 2.6 1 23 364 386 364 386 0.98

3 9 6.7e-06 0.00058 20.3 0.8 1 23 392 414 392 414 0.98

4 9 4.8e-06 0.00041 20.7 1.0 1 23 420 442 420 442 0.97

5 9 2.4e-05 0.002 18.5 1.4 2 23 537 558 536 558 0.96

6 9 2.5e-09 2.1e-07 31.1 1.6 1 23 564 586 564 586 0.98

7 9 0.003 0.26 11.9 0.9 3 23 594 614 592 614 0.97

8 9 0.00012 0.011 16.3 0.8 1 23 620 642 620 642 0.99

9 9 0.014 1.2 9.9 1.1 1 23 648 672 648 672 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	6.5e-05	0.0056	17.1	1.6	1	23	336	358	336	358	0.93
2	9	1.6e-08	1.4e-06	28.5	2.6	1	23	364	386	364	386	0.98
3	9	6.7e-06	0.00058	20.3	0.8	1	23	392	414	392	414	0.98
4	9	4.8e-06	0.00041	20.7	1.0	1	23	420	442	420	442	0.97
5	9	2.4e-05	0.002	18.5	1.4	2	23	537	558	536	558	0.96
6	9	2.5e-09	2.1e-07	31.1	1.6	1	23	564	586	564	586	0.98
7	9	0.003	0.26	11.9	0.9	3	23	594	614	592	614	0.97
8	9	0.00012	0.011	16.3	0.8	1	23	620	642	620	642	0.99
9	9	0.014	1.2	9.9	1.1	1	23	648	672	648	672	0.95

Sequence Information

Coding Sequence: ATGGCCATCAACTTCTCGGCCTCGTTCGCGGCCTGCATAGCAGCCGGATTGAAGGTGCCCCGCCAGATCATGTACTGCATCACCCAGGACACGGGCCAACCTTACGTGCTCTACAAGGACTCGCAGGACGCAGAGCGCAACCCGGGCGCCATCGGAGCCAGTCCCGCCCAGTGGGGCAGCGACATGTACCCCAACATCCAGCAGCAGGCCCAGCAGCACCTTAccgcgcagcagcagcagcagcagaacgcGGCGCAGGCAGCTGCCCAGGCGGCAGccgcagcggcggcagcgggtCAGCCGCAGAGTCCACCGGGCGGCGCCCAAGAGCCCCGTGACAACGGCAGCGGCGACGGCCGCCAGCAGAAGGTGTCGCCTTCGTCCAGCCCATATCCCTCggtgcaacagcagcagcagcaacagcagcaacagcaacagcagcgggcAAACGGGGGCGCCGACGAAGATGCCATGAACCAGCTCGGAAACCAGCAGAACCCTGCGCCCAACCAGAACCAAAGCAGTACCGACCCCCAGCACTCGGGCCCTAATGCGGGGGAGCCCGGTAACCCACATGTGCAGCAAaacggaggcggcggcggtccTCAGGGCGATCCCGGCAACAGCTTCCAAACGCCCGACTATTATGCTCCCCGTCACGCTGCGCCGCAAGGAGCGATGTTGGCGCCACCCGGCTTTCCGCCACTCCACTATCTCAACAAGGGAGTGCTGCCCATGGAGCAGtctggcggcggtggcggaggcGGGGGCGCCGGCGAGTCCTACTCGCTGCCCGAGCTCTTACCGGGCCAGCAAAACGGCCAGCAGAGTGCCGGTCCGACGAACGCCAATGCCAATGAGGGCGCGGCAGCAGTCAACGGCGGAGGAGTGGGCGGGGCATCGGGCGCGGGCGTAGGCCCTGGCGGCGGCGTGCCGACCGGAGGGCGCACTGGCAACGGGCCAGGACGCCCGCACAAGAACAAGCCGCACAGCGACTTGCGGCTGTTCAAGTGCCTGACCTGCGGCAAGGACTTCAAGCAGAAGAGCACGCTGCTGCAGCACGACCGAATCCACACGGACGCGCGTCCGTTTCCCTGCTCCGAGTGCGGCAAGCGGTTCCGGCAGCAATCGCACCTCACGCAGCATCTGCGCATCCACGCCAACGAAAAGCCCTTCACCTGCCCCTACTGCTCGCGCAGCTTCCGGCAGCGCGCCATTCTCAACCAGCACATACGCATCCATTCGGGTGAGAAGCCCTTCGCCTGCCCCGAGTGCGGCAAGCACTTTCGCCAGAAGGCCATCCTCAATCAGCATGTGCGCACCCACCAAGACGTCTCCCCACACCTCATCTTCAAGAACGGGCCACACCCGACGCTGTGGCCCTCAGACGTTCCATTCCCGGGAGAAGAGAACGACACCAAGGGCGACATTGCCAGTGCCGGCGGCGGCTACCACGACGAGGACTCCCAGGGAACCCCGGATGGTAGCGGCGGCATGCACTACCCGTCGTACTTCAAGGACGTTAAGGATCAACGCGCAGGCCAAAAGATACTGCCCGAGGTTCTGCAACACATCGGAGTGCGGCCGGCGAACATGCCGCTCTACGTGCGCTGTCCCATCTGCGACAAGGAGTTCAAGCAGAAGACGACTCTGCTCCAGCACGGCTGCATCCACATCGAGTCGCGGCCCTACCCCTGCCCAGAGTGCGGCAAGCGCTTCCGCCAGCAGTCGCACCTCACGCAGCATCTGCGCATCCACACCAACGAGAAGCCCTTCGGTTGCATGTACTGTCCGCGCTTCTTCCGCCAACGGACCATCCTCAACCAGCACTTGCGCATCCACACCGGCGAGAAGCCGTACAAGTGCGCCCAGTGCGGCAAGGACTTCCGGCAGAAGGCCATTCTGGACCAGCACACTCGCACCCACCAGGGCGATCGACCATTCTGCTGCCCGATGCCCAACTGTCGACGTCGCTTCGCCACGGAGAACGAGGTGACCAAGCACATAGACAACCACATGAACCCCAACACCACCAAGGTGcgtcgccagcagcagcaacagcagcagcagcaccagcagcagcagcaacagcaacagcagcagcaacagcaacaacagcaacagcagcagaacaacaacaacgctgTCGCTCAAGTCGCCTCGGTGGCCAACCACTTGATGAACGACGTCAAGAGCTTGGCGGCCCAGCAATTCCTCAACAATAACAACCCGACGTCGGCGGTCGACAACAAGGCAAACATCCTGCCTGTGCGCAGCATAGCGgccaatgcagcagcagccgctgtgGTGCAGCAGTCTGTGGTGAAGAACGAGCTGTACTTCCCGCAGTGTTACGGGCCTCCCTTCCAGCATCCCTTCCAGACACAACAGCAGGCCCAGCAGCCCAGTGTCGCGCACGCCAACGGGGGCCCGACGCCGCCGGTGACCGTGACAGTGGCCAACCCTGTGGCCCCCGGAGTAGTGGTCCAGCAGAATGCGTCTGCCTCCGTGGTGGCCCAGTGA
Protein Sequence: MAINFSASFAACIAAGLKVPRQIMYCITQDTGQPYVLYKDSQDAERNPGAIGASPAQWGSDMYPNIQQQAQQHLTAQQQQQQNAAQAAAQAAAAAAAAGQPQSPPGGAQEPRDNGSGDGRQQKVSPSSSPYPSVQQQQQQQQQQQQQRANGGADEDAMNQLGNQQNPAPNQNQSSTDPQHSGPNAGEPGNPHVQQNGGGGGPQGDPGNSFQTPDYYAPRHAAPQGAMLAPPGFPPLHYLNKGVLPMEQSGGGGGGGGAGESYSLPELLPGQQNGQQSAGPTNANANEGAAAVNGGGVGGASGAGVGPGGGVPTGGRTGNGPGRPHKNKPHSDLRLFKCLTCGKDFKQKSTLLQHDRIHTDARPFPCSECGKRFRQQSHLTQHLRIHANEKPFTCPYCSRSFRQRAILNQHIRIHSGEKPFACPECGKHFRQKAILNQHVRTHQDVSPHLIFKNGPHPTLWPSDVPFPGEENDTKGDIASAGGGYHDEDSQGTPDGSGGMHYPSYFKDVKDQRAGQKILPEVLQHIGVRPANMPLYVRCPICDKEFKQKTTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPFGCMYCPRFFRQRTILNQHLRIHTGEKPYKCAQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATENEVTKHIDNHMNPNTTKVRRQQQQQQQQHQQQQQQQQQQQQQQQQQQQNNNNAVAQVASVANHLMNDVKSLAAQQFLNNNNPTSAVDNKANILPVRSIAANAAAAAVVQQSVVKNELYFPQCYGPPFQHPFQTQQQAQQPSVAHANGGPTPPVTVTVANPVAPGVVVQQNASASVVAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00546100;
90% Identity: iTF_00480308;
80% Identity: -