Basic Information

Gene Symbol
hang
Assembly
GCA_035045145.1
Location
JAWNPG010000009.1:4768029-4783288[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.42 29 5.5 1.0 3 23 725 746 724 746 0.93
2 18 1.2 84 4.0 3.2 3 22 853 872 851 872 0.89
3 18 0.00089 0.063 13.9 3.3 1 22 968 989 968 991 0.90
4 18 0.087 6.1 7.6 0.1 2 21 1003 1022 1002 1023 0.93
5 18 0.001 0.073 13.7 0.2 2 23 1152 1174 1151 1174 0.95
6 18 0.003 0.21 12.2 0.1 1 23 1182 1205 1182 1205 0.96
7 18 0.00023 0.016 15.7 0.2 2 23 1291 1312 1290 1312 0.97
8 18 0.00043 0.03 14.9 2.9 2 23 1406 1428 1405 1428 0.97
9 18 0.034 2.4 8.9 0.2 2 23 1437 1459 1436 1459 0.95
10 18 0.0018 0.13 12.9 0.1 1 23 1472 1495 1472 1495 0.97
11 18 0.00019 0.013 16.0 1.1 1 23 1546 1568 1546 1568 0.99
12 18 0.0029 0.2 12.2 0.9 1 23 1576 1599 1576 1599 0.96
13 18 0.074 5.2 7.8 0.3 2 19 1607 1624 1606 1625 0.94
14 18 3.9e-05 0.0028 18.1 0.4 3 23 1725 1745 1724 1745 0.98
15 18 0.0075 0.53 10.9 0.1 1 23 1780 1802 1780 1802 0.97
16 18 0.00088 0.062 13.9 0.6 2 23 1889 1911 1888 1911 0.93
17 18 0.0096 0.67 10.6 0.3 3 23 1967 1987 1967 1987 0.98
18 18 5.7e-05 0.004 17.6 2.3 1 23 2427 2449 2427 2449 0.99

Sequence Information

Coding Sequence
ATGACAACGACATCGACGTCGCCAGTGTGCTCCTTTAATGCGAAACCGTTATACACACTGCTGGcacccattcccattcccctGCTGCTCGGAGCCGGCAGAGGTGGCCACACCCGAGCTGTGCTGATGGGCAATCTACTCCTGCTCTTGCTGAGCGGCGTTTCCTGTCTacgcgagctgctgctgctgctgctctgctacTGGCTGGCCCCATTTGATTGTGCAAGCACTGGCGATGACGACAacgacgccgacgacgacgactacgACGAGACCGAGCCAAACGTTGTTTCccccagccgcagccgcagcccctGCCCGTGTCGTGTCCCTCAGTCTCAATGGCACTTGCCCGtgagcaacatcatcatcattggaAATGGAAACGGAATCGAGCGTTCGCATTTGTGCTTGTCCACGCCATGCCGTGTGCTCCGGCTCAGTGCCGTCTGCCTCTGGCTTTGCTTGAAGTGCCAAGTCACGATGcccgacgacgacggcggcgacggcaacgaCGACGCGACGGCCATCGCCGTTTATTGGCACGaaaaagcagcagcacaaaacgTAGAGCGCAATGAGCGGCAGCGGCGCCCGAACGAACGGCCATTcaacggcaacaaaattttCGAGGCCGTCACCATCGACGAGATTGAGAGCGGTGTGCCCAGAGAGGGCAGGAGGAGACGTTCGTGCGTGCATGAGGCAAAGACGTTTGGTGGTGTTCCTGCTTCAGTGGCACTTGAGAAAGAGATGTGCCCAACAGGATGTCGCCGTGCGGGCGGCTTGGTGTGGATCACGCCATTGGATCGTCTGTCGCTGCATATTTGCCATGCCTGCATCAGCTATTTGAACTCCTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGTCcaagcagcggcagtggctAGAGAGCGATAAAAGCAAGCAGCAGACGCTTCTCGGATATTTGGATTTGAACAAAACGGAGAATGGCAGCAGCTCCAttgaacagcaacagcaacagcagcagcagcagcacgaatCGAATATCGATTCGGCAACGATTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGCATACCTTCGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCaaagcaacagctacaacagcaacaacagcaacaacaacaacagcagcagcagctacaacagcagcagcagcaacaacaacaacaacaggcgcAGGTGCAGCATGCACCAAGAGCAACGAGCGCGGCGGCGGAATCACAGCAAACGCTGCAGACCCTTTTATTGCAGGTGcccgcagcggcagcattgGCAACGACGTcaacccagcagcagcagcagcaacagcaacagcgcaaatatcaacagcagcaacgtgTCAAGCAGCAACATTAccatcagcaacatcaacagagtcagcaacaacaacaacagcagcagcagcagcgcttgAGTCGCATTCGTCAGCCGCGACGccagcaacaggcaacaatGTCTGCCCAGCGAATGGTCAAGTTTAAGCCGAAAGTGTATTTGCCATTGGATATATCGGTGCCACCGTTGCCAGCGTTGCCGTTGCCGACGACGTCGCAGCCAGCTgacactgttgctgctggtgctaaGTTGgcgccgttgccgctgccgcttgATTTTaggcagagtcagagtcagcaTCTGAATCCGAATCCGAATGCGAGTCAGAGTCAGCAGAAACATGGCAacgtgctgccgctgccgttgccattgccattgccgccGTCGACGCCGCTGTTGCCACCGCTGCCGGCTGCCACAATGACCAGCAACGCCGCTGCCTCtagctctgcctctgcctctgtctcagctacagccgcagccgcagccgcagccacaaaCACGACTCCTCTGCTCATGCCGCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCCATTGATGATACGGACGATGACTTCCAGATGAAGTGCATAGACGAGTCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACACGGCGCAACACGGCGTGACGGCGGTTGCGGCGGCGGCATCTCTGCCCGCCAGCGCGGTTGCAAACGTGGCCGCCGCCGGCGACTCAAAGGTGGCCAGCTGTCGGGCCTGCAGTCTTCAGTTCTCGACGCGCGCGAATGCCCGACGCCACGAACGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGATTCACCCAACAATACGCCCATCACAAAGCCAACGCCGGCCCTGGCCGCCGCTCTAGACATACAGCGCGCCGCCGCGGCGGCAGCGGCCACCGCAGAGGCAACCAAAGCCGCCGCCGGTGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTCATGAATACGTTCATCAAGTGCGAAAACGGCGGCTTCGACTACGACAATCCGGAACAATACCAGCAGCTGCTCACGCGTGACAAGGTGGAGTTCATACAGGAGAACAACGAGTTCCTCGAGCAGTACCAGACGATGacctgccgctgctgcaacaAGTACTTCAACACCTACAAGAACTTCATGGCGCACGTGCGCAAAAAGTATCCACTGTTGCCGCGTAACCTCTGCTTCAACTGCCTGAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTAAAGAAGCGCAACTGCATCAATCTGTATCGCGTTCTGAACGCGCTGCGCCTGAAGCAGCCAAACTTTTCGCACGCCAACGCATCCGGCGTTGCCGTCTCGGCCGACTTGAGTCTAGGCCagggggcagcagcagcagcagcagtagaatcACCATCGGAGCGACCAGAGAAGCTGCGTGCCAAGGAACTGCTGGTGAACAAGCTGTACGAGTGCAAGCTGTGCCCCAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCACGTGTACGACAAGCACGCGGATGTGCAGCGCAAGGACAACAATTCGATACAGTGCACCTTCTGCGGCTTGGACTTTGCCGATCCCGTGGATCGGCGTCGCCACTACAACAACATGGAGTGCATTGTGCGGCTGCGCTGCATGACCTGCGATGCGAAGCTGGAGACGCATCAGCGTTTCCTCGACCACGTCTACCAGGATCATCTGGGCGGCGTGAGCAGTGATAATGCCTCCACGGCCAACAGCGGCATGGATCATTCGCCGGGCAAGCGCAGCCTGCTGGGCGCTCTGGGCATCGGCATGAGTCAGTCCTCCAATGACGAGTCGCGGAGCAgcacccacaacaacaacaatgctgcGGAAGCGGCCTTCACCTCGACACCCAAgccagctggagcagcaggcggcggcggcgcatcagcagcagcaggcactgGCGGCTCCGCGTCGGGCGGTCGCGATGCACCCAAGTCGCAGTATTTCTCCCGCATGCCACAGGTGTGCCCGATCTGTGGGCAGCagtacaacaactacaacaacgtgCTGCGCCACATGGAATCGAAGCATCCCAACAAGCTGCCCGAGACGTACAAGTGCGTGCGCTGTGGACTGGGATATCCGCGAATCTCGTACCTGCGCGAGCACATGATCAATGTCCATGGCGTGGACAAGAATCGGCACTCGGGCGGCTTCGAGTACATTGTGAATGCGGACGCAGTGAAGCTGGCGGATGGCAGCATGCCGAACGTCTATACGGGTCGATATGACTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgatgacgatgatgaggaAGGCGGCAGCGTGGCCAAGAAGATGCGCCtcgacgacagcagcaacaacagcagcatcaacatgAGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAACGCGGTGTTCAGCAACAACATTGGCCTCTCGAATCACATGCGCTCCCATTATACGGCTGCGACGGCCACGAATGCCGCACTAGCGGCTGCCAATCGCATGACGCCCAAATCCTTGACAATTACCGCAACTCCGCCATTGGACACGGCTGCAGCCACGTCCACAAGcactgcggcagcagcagcggcgcctgccacagcagcagctgctgcaactccAACTGTTGCCGCTGGTGGTCTTCCGCCCGCAATGGTGCATCAGACGCCGCAGGAGCAGGCCGTGTTCCGGCGCAGCCTGGACCAGGCGGCCGATCGTCGCTTCCGGCGCATGCGCTGCCGCATCTGCCAGCGCAGGTTCAGCTCGAAGAAGTCGTATCGCTACCACATGCTCACCGACCATCAGGTGCAGAACGTCCAGTTCATCAAGTGCAAGCTCTGCAATGCGGAGTTCGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGACGAGATGATTGTCAAGCAGTTCGAGTGCGACATCTGCTCCATTGTCTACAGctcggagctggagctgcagcagcacaagcGCAGCGTGCACAAGTCCCAAACGGGCGCCAATGATGCCTCCAAATCGGCAACAGGAACCAAATCGTCCACCGCTACCTCAGCTGCTGACCTGGCCGAGACATcaggcgtgggcgtgggcactGGAGCCGGTGCAGGTGCAGCCGTCCTGCCCCTGTACTGGTACCAGTGCAAGTACTGCCCATCCAACTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAACGACTATTCGTGCAAGGATTGCGGCAATGTGTACAGCGGGCGCAAGAGCCTCTGGGTGCATCGCTATAAGAAGCATCCGCAGGTTCCAGATCCAGTCGAGTGCACGCTCTGCCGTAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCACACGCCCACCTGCAATCGTAAGCCCATCACTGCCACCGGCGCACATCAGCAGGatccgcagcagcaacaccagcagcaacagcagcagcaacagttgcagctgcaacagcaacgcgCCATATTCAAGCACAAGACGggcgacgatgatgatgaggaggAAGATgatcagctgttgctgctggatgACGGTGGTgtgggcagcgacagcaatgGAGCGAATGCTATCCATGCGGCAGCCACCAGCAACAATCCAAATACGATAAATGCGAGCACAATGAAGATACGCATCCCGGAGGTGGCCTGCACCATCTGTGGGGCACGCTTCACCGACCAGGAGATGTTCACCAAGCACATACAGAAGCACGAACAGGATCTCTATGTGGACAATCCGTTGGCGGCCATGTTCGACGATGGCCCCGCCGATGCTGGCCAATTCAAGGTGGAGCGTCAGAACGAGAATGGGGAATATGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaaTCTCATCATCGACGGCGAAGCGACAACGACGttgaacaacagcagcagcaacaacaacaacaacaacaattcgctGAGCTCCTCGTCGATGCTGCGCGAGCTGCATGCAGTGGGTCTGATGcccaaccagcagcagcaccagaagcagctccagcagcagcaacaacagcagcagcagcggaacaACACGTCCTCGAGCGGATCGAGCAAGTCGATGAAGCGGAAACGTGAACTGAAATGCGAATACTGCGCCTCCACCTtcattagcaacaacaacctgCGACGCCACATGTACGAGCTGCACAAGCACGAGGTTAGCAATCTGCCGGAGCCGCCAGTGATCGAGGTGGATGAGCCGCTGACGTGCCGCCGTTGCGGCGATATACGCTTCGAGACCAAAGAGCTGTGGATCGAGCATAAGCTGGCGGACGCCAAGGTGGTGCGTCCGTTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCACCTCAAGGAGGATGTGATAGTGCCCGTGGCGACGGTCACCAAGGCGGCGCTGCCCACGAAGAATGCGGCGGCAAAGGCGACAGCTGGAGCAGCGGgaacaacaggagcagcaggagcaggagcaggagcagcagcaacaacagcagcagcaacagcggcgacagcagcaaagGGCGTCACAGCTGGCGGCAGAGTCAATAAGAATaagcagctggaggagcagcTGAGCATGAAGGTGGcaacgaagcagcagcagcagcaggaggatgAGGAGGATGGCACTGATatggatgatgatgatgaggaagACAGCGACAGTGGCGAGGGCGAGAGCACGAgcgctgatgatgatgatgacgacgatgatgacgatgaggGCGACGTTGATGAGgacgatgatgaggatgaAGATGTGGATGGAGTTGTTGTcgagcagcaattgctgcagcagaaacaacagcagcagcagcagcaacaacagaccCTCAACAACGTAGCTGCGaacgatgatgacgacgatcTCATTGAGGAAGTCATCGAGGAGGATGGCATTGTCGAGGAGCTGGACGACGATGAGGACGATGAGGGCGACGAGGATGGCAACACAACCGACGAGCACCAGCAGCTGGCAGCCGGCAATGCAAAGCAACAGCCGCGACGCCTCAACTTTGACTATTCGCGCGCCAAGCTGAACGGGAATGggaatggcaatggcaaacagacgccacagcaacagcagcagcagctgggcaaGGCGAAGGGGCAGCTGGTTATGCACAGCTCCGAGGATGAGGAGGATGGTGTCGATGACGAGGAAGATGAGGAGGGCGTGGGCGAAGCGATGACCATTGATGATATTATTGAAGAAGATGATGGGgaggatgaggatgacgaTGTGGTTGGGGTCGATGGTGGTGTTGTTgaggacgacgatgacgacgatgatgatgaggatgatgtTGGGGAAGATAtggacgaggacgacgacgatgatgatgacaacgatgaagacgacgacgacgatgatgatgatgatgacgatgatcaTGACGATGGCGGCGTCAATGTCgttggcaacaacaatcgtCGTCGCGACGGTGCTGTGATGGTCAGCGGCATCAGCATTGGCGACGGTGGTGAGGCGGATGATGATGGTGTTGCCGATGCTGATGTGGATGGTGATGTGGATGCTGATGCTACATCATCATCGGAGAGCGAGtcgacaacgacaacatcgCATTCAATTGGTGAGCGGCGTAAAAAATCAGTAGTTAAATCAGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCAACTGCAGTCACATATTAAAAGCCATTTTCTGAATGGGCCGTCGGCgggtggcggcggcagcagcagcagcagcagcagcagcaatagcagcaacagcagcagcagcggcggcagcggaaGCAGCAGAAGGATTGGTGccggcgctggcagcggcagcagcagcagcggcagtggcagcaggaccaacaacaacaacaataataataataataataataataccaataataacaataataataacagcaaaagcaaaaccaaaaagTCCGGCTTGgatgccgccgctgctgctgcaacaacatcaacaacaacggcaacaacggcagcaacaaccagatcagcaacagcaacagttgctgctgaagcagctgcagcaacggcagctgccGACGCCGCAAACAGCTTGAACTGA
Protein Sequence
MTTTSTSPVCSFNAKPLYTLLAPIPIPLLLGAGRGGHTRAVLMGNLLLLLLSGVSCLRELLLLLLCYWLAPFDCASTGDDDNDADDDDYDETEPNVVSPSRSRSPCPCRVPQSQWHLPVSNIIIIGNGNGIERSHLCLSTPCRVLRLSAVCLWLCLKCQVTMPDDDGGDGNDDATAIAVYWHEKAAAQNVERNERQRRPNERPFNGNKIFEAVTIDEIESGVPREGRRRRSCVHEAKTFGGVPASVALEKEMCPTGCRRAGGLVWITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLESDKSKQQTLLGYLDLNKTENGSSSIEQQQQQQQQQHESNIDSATIAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQQQQQQQQLQQQQQQQQQQQAQVQHAPRATSAAAESQQTLQTLLLQVPAAAALATTSTQQQQQQQQQRKYQQQQRVKQQHYHQQHQQSQQQQQQQQQQRLSRIRQPRRQQQATMSAQRMVKFKPKVYLPLDISVPPLPALPLPTTSQPADTVAAGAKLAPLPLPLDFRQSQSQHLNPNPNASQSQQKHGNVLPLPLPLPLPPSTPLLPPLPAATMTSNAAASSSASASVSATAAAAAAATNTTPLLMPPLPAVPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALDIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFSHANASGVAVSADLSLGQGAAAAAAVESPSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCTFCGLDFADPVDRRRHYNNMECIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGMSQSSNDESRSSTHNNNNAAEAAFTSTPKPAGAAGGGGASAAAGTGGSASGGRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSMPNVYTGRYDYVMKDLMSITNGGTLDDDDEEGGSVAKKMRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTAATATNAALAAANRMTPKSLTITATPPLDTAAATSTSTAAAAAAPATAAAAATPTVAAGGLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSSELELQQHKRSVHKSQTGANDASKSATGTKSSTATSAADLAETSGVGVGTGAGAGAAVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPVECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDPQQQHQQQQQQQQLQLQQQRAIFKHKTGDDDDEEEDDQLLLLDDGGVGSDSNGANAIHAAATSNNPNTINASTMKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFKVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLIIDGEATTTLNNSSSNNNNNNNSLSSSSMLRELHAVGLMPNQQQHQKQLQQQQQQQQQRNNTSSSGSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDIRFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATVTKAALPTKNAAAKATAGAAGTTGAAGAGAGAAATTAAATAATAAKGVTAGGRVNKNKQLEEQLSMKVATKQQQQQEDEEDGTDMDDDDEEDSDSGEGESTSADDDDDDDDDDEGDVDEDDDEDEDVDGVVVEQQLLQQKQQQQQQQQQTLNNVAANDDDDDLIEEVIEEDGIVEELDDDEDDEGDEDGNTTDEHQQLAAGNAKQQPRRLNFDYSRAKLNGNGNGNGKQTPQQQQQQLGKAKGQLVMHSSEDEEDGVDDEEDEEGVGEAMTIDDIIEEDDGEDEDDDVVGVDGGVVEDDDDDDDDEDDVGEDMDEDDDDDDDNDEDDDDDDDDDDDDHDDGGVNVVGNNNRRRDGAVMVSGISIGDGGEADDDGVADADVDGDVDADATSSSESESTTTTSHSIGERRKKSVVKSAAHGAAADQSNSSYTCDLCQLCFDSQEQLQSHIKSHFLNGPSAGGGGSSSSSSSSNSSNSSSSGGSGSSRRIGAGAGSGSSSSGSGSRTNNNNNNNNNNNNTNNNNNNNSKSKTKKSGLDAAAAAATTSTTTATTAATTRSATATVAAEAAAATAAADAANSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00476771;
90% Identity
iTF_00544634;
80% Identity
-