Basic Information

Insect: Drosophila melanica
Gene Symbol: su(Hw)
Assembly: GCA_004143765.1
Location: SCDT01003258.1:9563-12838[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00043 0.044 14.4 2.2 1 20 230 249 230 251 0.94

2 8 1.8e-06 0.00018 21.9 0.4 3 23 302 323 300 323 0.93

3 8 0.0061 0.62 10.8 0.1 1 23 329 351 329 351 0.97

4 8 4.9e-07 4.9e-05 23.7 2.5 1 21 358 378 358 379 0.95

5 8 2.1e-06 0.00021 21.7 0.6 2 23 391 412 390 412 0.96

6 8 0.0059 0.59 10.9 1.8 1 23 432 454 432 454 0.97

7 8 2e-05 0.002 18.6 0.2 1 21 462 482 462 486 0.92

8 8 6.3e-05 0.0063 17.1 0.3 3 23 506 527 504 527 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00043	0.044	14.4	2.2	1	20	230	249	230	251	0.94
2	8	1.8e-06	0.00018	21.9	0.4	3	23	302	323	300	323	0.93
3	8	0.0061	0.62	10.8	0.1	1	23	329	351	329	351	0.97
4	8	4.9e-07	4.9e-05	23.7	2.5	1	21	358	378	358	379	0.95
5	8	2.1e-06	0.00021	21.7	0.6	2	23	391	412	390	412	0.96
6	8	0.0059	0.59	10.9	1.8	1	23	432	454	432	454	0.97
7	8	2e-05	0.002	18.6	0.2	1	21	462	482	462	486	0.92
8	8	6.3e-05	0.0063	17.1	0.3	3	23	506	527	504	527	0.96

Sequence Information

Coding Sequence: ATGAGCGCCAGCAAGGAAGCCAAAACCACAGACGCCCCCGAGGCGAACCCCGCCCCAGCCCCTAGCAGCGACGGCAGCACAGTGATAAAAATTTTAGACGTGGATCAGATCGTGTCACCCAAGGAGAAACGGTCAGGCGCACGCATGAAGCTGCTTAACGACGTGGCCGCCAAGGCTGCCAGCAAGTCCGCCGCCTCGCCCCGACTCAAACAGGAGAAGCGCACTAGCATCAAAATACTCAACAATGATGAATCGGAAAGCAGCCCCAAGGGCGGCGACAGGCGCTCTACGGCCAAAACTCCCAGTGCCGCAGGCAGTGGCGTCAAAATCTTAAACGAGAAACGTATTTCGTCGGGCTCCGCAGCAGTGGAAACGGCCAAAATCAAGACGTCGCCcagcaagaaaaagaaaatggatCACTATGTGCTGCAAGCCATCAAGAGCGAGAACAGCAAAGCGGAGAACACGACGAGCGTGGTGGTGGTCGAGGACGACGACACAATTGACTTCATACTCGCTGACGAAGACGCCGAGCTGGGCGCGGCCAAGGAGAACGGCGATGAGTTTGTAGTCTCTGGCGTCGATGAagaggacgaggacgacgacgaggacgagggCGAGGCAGCGGATGAGGCCAGCGCAAATCGCgcaagtggcaacaacagcgagcTCAAAGAAATGGTGGAGCACGTGTGCGGCAAGTGCTACAAGACATTCCGTCGCGTCAAAAGCCTAAAGAAGCATCTGGAGTTCTGTCGCTACGACAGCGGCTATCACCTGCGCAAGGCGGACATGCTAAAGAACCTAGAGAAGATCGAAAAGGATGCGGTCGTCATGGAGAAGAAGGAcatctgcttctgctgcagcgAAAGCTACGACACCTTCCATCTGGGCCACATCAACTGCCCGGACTGCCCCAAGTCGTTCAAGACACAGACCAGCTACGAGCGTCACATCTTCATCACACACTCGGAGTTCAACGATTATCCCTGCTCCATATGCAATGCCAAGCTGCGCAGCGCCGCCCTGCTGAAGCTCcatgagcagcagcaccaactgCGCGGCAAACCGTTCGCCTGCAAGATCTGTGGCAAGGACTTTACGCGCTCATACCACTTGAAGCGTCATCAGAAATACTCGTCGTGTTCGGCCAACGAGAACGACACCATGAGCTGCAAGGTGTGCGATCGTGTATTCTATCGCCTAGACAACCTGCGCGCCCATCTCAAACAGCACCTGGGCACCCAGGTGGTCAAGAAACCAGAGTACATGTGTCATACGCATCTACGTCCCTACTCCTGCTCGCTGTGTATCCAAAAGTTCAAGACGGAAAAGCAACTTGTGCGCCACACCAAGGAGCACACGCGTCAGAAACGCCCCTCCTTTGCCTGCACGGAGTGCACACGCAGTTTCCGCACCAGCGCCCTGCTCAAGGAGCACATGGACGCAGGTGACCATTCGCCTGTCAAACCCACACGAGCTAAGCGCTCGGCTAAGATGATCGAGCGCACAGACTGCGCCATTTGCGACAAGAACTTTGACAGCACGGGGACACTCAGAAATCACATACGCAACGTGCACGAGTGCAACCCGGATGACATATTTGGCACTGAGCCACCGGCCAAACGCAGAGCCAAAAAGACTGTGGCTGTGCTGGAGGAGCAGGACGATGATGAGGAGCCAGAGGAAGACTTGACGGGTGCCAACACATCGGCGGGTTCGCTCATCTCCAGCAAGACGGACGGTAATGGGGTTGTGGTTCGCGAATTTATCGTGGATGAGGGTAACGGTACCGCGCAGACCATTGTCCTCGAGAATGAAGTGTACACGATTCTTCCTCTGGAGGACGGCGCTGCAACTGAAGCTTCGGGAGAGGACAACGTCAAAGCAGAGTCCAAGGAGAAACAACAGCAGGCGGTCTCGCCGGTAGTCAAGAAGGAGCAGCGCAAATCGCTAGCCGCCAGCTTGGCCGCTGCCATTGCGGATAATCTGGAGGAGCCGTCGAGCGATGATGATTTCGGTGGTGAGGTGCTCACCGAAGAGGACCTGAAGCTTAAGGAAAATATAGCCAAGCTAATAGACATGTTGGTGGATCCGCAGACACTTAAGAAATATGGATGGCCGAACAGCTCCGAGGAGTCGGTGCTGTGTAAGGTCATCGAGAATTGTGGCCACGATCTGGCCAAAGGCAGCGAGAATTACGCCGAGTTGGACTACGGCAGTCGCATGCGCGAGTACTGCAAGCTGCTGTTCACGGTGGTTATTCACAATGATTCCATTAAGGCGCTGCTCAACAATTTTCCCATCGACGACGTCATTGAGTATGTGCTGGGTGACGAAGATCAGGAGCAGGATCAAGAGACCGAAAAGGgcaaggacaaggacaaggagGCCGATAAATCGGATGCGGATACCAGACAGGATGCTGACGCTTAG
Protein Sequence: MSASKEAKTTDAPEANPAPAPSSDGSTVIKILDVDQIVSPKEKRSGARMKLLNDVAAKAASKSAASPRLKQEKRTSIKILNNDESESSPKGGDRRSTAKTPSAAGSGVKILNEKRISSGSAAVETAKIKTSPSKKKKMDHYVLQAIKSENSKAENTTSVVVVEDDDTIDFILADEDAELGAAKENGDEFVVSGVDEEDEDDDEDEGEAADEASANRASGNNSELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSAALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHTHLRPYSCSLCIQKFKTEKQLVRHTKEHTRQKRPSFACTECTRSFRTSALLKEHMDAGDHSPVKPTRAKRSAKMIERTDCAICDKNFDSTGTLRNHIRNVHECNPDDIFGTEPPAKRRAKKTVAVLEEQDDDEEPEEDLTGANTSAGSLISSKTDGNGVVVREFIVDEGNGTAQTIVLENEVYTILPLEDGAATEASGEDNVKAESKEKQQQAVSPVVKKEQRKSLAASLAAAIADNLEEPSSDDDFGGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYGWPNSSEESVLCKVIENCGHDLAKGSENYAELDYGSRMREYCKLLFTVVIHNDSIKALLNNFPIDDVIEYVLGDEDQEQDQETEKGKDKDKEADKSDADTRQDADA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00495995;
90% Identity: iTF_00547494; iTF_00567669; iTF_00561175;
80% Identity: -