Basic Information

Insect: Drosophila micromelanica
Gene Symbol: su(Hw)
Assembly: GCA_004143905.1
Location: SCDX01001171.1:8361-12387[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00052 0.036 14.3 2.2 1 20 247 266 247 268 0.94

2 10 2.2e-06 0.00015 21.8 0.4 3 23 319 340 317 340 0.93

3 10 0.0073 0.51 10.7 0.1 1 23 346 368 346 368 0.97

4 10 5.8e-07 4.1e-05 23.6 2.5 1 21 375 395 375 396 0.95

5 10 2.5e-06 0.00018 21.6 0.6 2 23 408 429 407 429 0.96

6 10 5.4 3.8e+02 1.7 8.0 1 23 440 472 440 472 0.54

7 10 1.2e-06 8.1e-05 22.7 3.0 1 23 478 500 478 500 0.98

8 10 0.0071 0.5 10.7 1.8 1 23 504 526 504 526 0.97

9 10 2.4e-05 0.0017 18.5 0.2 1 21 534 554 534 558 0.92

10 10 7e-05 0.0049 17.0 0.3 3 23 578 599 576 599 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00052	0.036	14.3	2.2	1	20	247	266	247	268	0.94
2	10	2.2e-06	0.00015	21.8	0.4	3	23	319	340	317	340	0.93
3	10	0.0073	0.51	10.7	0.1	1	23	346	368	346	368	0.97
4	10	5.8e-07	4.1e-05	23.6	2.5	1	21	375	395	375	396	0.95
5	10	2.5e-06	0.00018	21.6	0.6	2	23	408	429	407	429	0.96
6	10	5.4	3.8e+02	1.7	8.0	1	23	440	472	440	472	0.54
7	10	1.2e-06	8.1e-05	22.7	3.0	1	23	478	500	478	500	0.98
8	10	0.0071	0.5	10.7	1.8	1	23	504	526	504	526	0.97
9	10	2.4e-05	0.0017	18.5	0.2	1	21	534	554	534	558	0.92
10	10	7e-05	0.0049	17.0	0.3	3	23	578	599	576	599	0.96

Sequence Information

Coding Sequence: ATGCTTGGTCGCATTGATGTGAAAACAGCTGATGGACCCCGTTCGCACGCGATGAGCGCCAGCAAGGAGGCCAAAACGACAGACGCCCCCGAGGCGagccccgcccccgcccctaGCAGCGAAGGCAGCACAGTGATCAAAATCTTGGACGTGGATCAGAGCGTGCCACCCAAAGAGAAACGGTCAGGCGCACGCATGAAGCTGCTTAACGACGTGGCAGCCAAGGCTGCCAGCAAGTCCGCCGCCTCGCCCCGACTCAAACAGGAGAAGCGTACCAGCATCAAAATACTCAACAACGATGAATCGGAAAGCAGTCCCAAGGGCGGCGACAGGCGCTCTACGGCCAAAACTCCCAGTGCCGCAGCCAGTGGCGTCAAAATCTTAAACGAGAAGCGCATTTCGTCGGCCTCCGCAGCAGTGGAGACGGCCAAAATCAAGGCCTCGCCcagcaagaaaaagaaaatggatCACTACGTGCTGCAAGCCATCAAAAGCGAGAACAGCAAAGCGGATAACACGACCAGCGTGGTGGTGGTTGAGGACGACGACACAATTGACTTCATACTCGCTGACGAAGAGGCCGAGCTGGGCGCAGCCAAGGAGAACGGCGATGAGTTTGTAGTCTCTGGCGTCGATGAAGAGGACGaggatgatgacgacgacgagggCGAGGCAGCTGGTGAGGGCAGCGCAAATCGCgccagtggcaacaacagcgagcTCAAAGAAATGGTGGAGCACGTGTGCGGCAAATGCTACAAGACATTCCGTCGCGTGAAGAGTCTAAAGAAGCATCTGGAGTTCTGCCGCTACGACAGCGGCTATCACCTGCGCAAGGCGGACATGCTGAAGAACCTGGAGAAGATCGAGAAGGATGCGGTCGTCATGGAGAAGAAGGACAtctgcttctgctgcagcgagagctACGATACCTTCCATCTGGGCCACATCAACTGTCCGGACTGCCCCAAGTCGTTCAAGACACAGACCAGCTACGAGCGTCACATCTTCATCACACACTCGGAGTTCAACGATTATCCCTGCTCCATATGCAATGCCAAGCTGCGCAGCGCCGCCCTGCTGAAGCTCcatgagcagcagcaccaactgCGCGGCAAGCCGTTCGCCTGCAAGATCTGTGGCAAAGACTTTACGCGCTCATACCACTTGAAGCGCCATCAGAAATACTCGTCGTGTTCGGCCAACGAGAACGACACCATGAGCTGCAAGGTGTGCGATCGCGTCTTTTATCGCCTGGATAATCTGCGCGCCCATCTCAAGCAGCACTTGGGCACCCAGGTGGTCAAGAAACCGGAGTACATGTGTCATGTGTGCAAGAACTGCTTCTACAGCCTGTCCACGCTCAATCAATCGTTTGCTGTCAAGGAGGTGCTCAATCGCCACATGAAGCGGCACACCGGCGAGCGTCCACACAAGTGCAACGAGTGCGGCAAGAGCTTCATACAGGCCACACAGCTGCGCACGCATTCCAAGACGCATCTGCGTCCCTACTCCTGCTCGCTGTGCATCCAAAAGTTCAAGACAGAGAAGCAACTTGTGCGGCACACCAAGGAGCACACGCGTCAGAAACGCCCCTCGTTTGCCTGCACGGAGTGCACACGCAGTTTCCGCACCAGCGCCCTGCTCAAGGAGCACATGGACGCAGGTGACCATTCGCCTGTCAAACCCACGCGAGCTAAGCGCTCGGCTAAGATGATCGAGCGCACGGACTGCGCCATTTGCGACAAGAACTTTGACAGCACCGAGACACTCAGAAATCACATACGCAACGTGCACGAGTGCAACCCGGATGACATCTTTGGCACTGAGCCGCCGGCGAAGCGCAGAGCCAAAAAGACTGTGGCTGTGATGGAGGTGCCGGACGATGATGAGGAGCCTGAGGAAGAAGAGACGAGTGCCAACACATCGGCGGGTTCGCTCATCTCCAGCAAGACGGACGGCAATGGGGTTGTGGTGCGCGAATTTATCGTGGACGAGGGTAACGGCACCGCGCAGACCATTGTACTCGAGAATGAAGTGTACACGATTCTGCCTCTGGAGGACGGCGCCGCAACTGAAGCTTCGGGAGAGGAGAACGTCAAGGCAGAGTCCAAggagaaacagcagcaggcggtCTCGCCGGTAGTCAAGAAGGAGCAGCGCAAATCGCTAGCCGCTAGCTTGGCTGCTGCCATTGCGGATAATCTGGAGGAGCCGTCGAGCGATGATGATTTCGGTGGTGAGGTACTCACCGAAGAGGACCTGAAGCTCAAGGAAAACATAGCCAAGCTAATAGACATGTTGGTGGATCCGCAGACACTTAAGAAATATGGATGGCCCAACAGCTCCGAGGAGTCGGTGCTGTGTAAGGTCATCGAGAACTGTGGCCACGATCTGGCCAAGGGCAGCGAGAACTATGCCGAGTTGGACTACGGCAGTCGCATGCGGGAGTACTGCAAGCTGCTCTTCACGGTGGTTATTCACAATGATTCCATAAAGGCGCTGCTCAACAATTTCCCCATCGACGACGTCATTGAGTATGTGCTGGGTGACGAGGACCAGGAGCAGGATCAAGAGACAGAAAAGGGTAAGGACAAGGAGGCCGATAAATCGGATACGGAAACCAGACAGGATGCCGTTGAAGCCGAGGCTTAG
Protein Sequence: MLGRIDVKTADGPRSHAMSASKEAKTTDAPEASPAPAPSSEGSTVIKILDVDQSVPPKEKRSGARMKLLNDVAAKAASKSAASPRLKQEKRTSIKILNNDESESSPKGGDRRSTAKTPSAAASGVKILNEKRISSASAAVETAKIKASPSKKKKMDHYVLQAIKSENSKADNTTSVVVVEDDDTIDFILADEEAELGAAKENGDEFVVSGVDEEDEDDDDDEGEAAGEGSANRASGNNSELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSAALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYSCSLCIQKFKTEKQLVRHTKEHTRQKRPSFACTECTRSFRTSALLKEHMDAGDHSPVKPTRAKRSAKMIERTDCAICDKNFDSTETLRNHIRNVHECNPDDIFGTEPPAKRRAKKTVAVMEVPDDDEEPEEEETSANTSAGSLISSKTDGNGVVVREFIVDEGNGTAQTIVLENEVYTILPLEDGAATEASGEENVKAESKEKQQQAVSPVVKKEQRKSLAASLAAAIADNLEEPSSDDDFGGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYGWPNSSEESVLCKVIENCGHDLAKGSENYAELDYGSRMREYCKLLFTVVIHNDSIKALLNNFPIDDVIEYVLGDEDQEQDQETEKGKDKEADKSDTETRQDAVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00495995;
90% Identity: iTF_00541903;
80% Identity: -