Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: su(Hw)
Assembly: GCA_004149445.1
Location: SCDR01001180.1:3377-7611[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00055 0.066 14.2 2.2 1 20 262 281 262 283 0.94

2 11 2.3e-06 0.00027 21.7 0.4 3 23 334 355 332 355 0.93

3 11 0.0078 0.94 10.6 0.1 1 23 361 383 361 383 0.97

4 11 6.2e-07 7.5e-05 23.5 2.5 1 21 390 410 390 411 0.95

5 11 2.7e-06 0.00032 21.5 0.6 2 23 423 444 422 444 0.96

6 11 8.6e-05 0.01 16.8 5.3 1 23 455 477 455 477 0.99

7 11 0.45 54 5.1 0.3 9 23 496 510 494 510 0.90

8 11 1.2e-06 0.00015 22.6 3.0 1 23 516 538 516 538 0.98

9 11 0.0075 0.9 10.7 1.8 1 23 542 564 542 564 0.97

10 11 2.6e-05 0.0031 18.4 0.2 1 21 572 592 572 596 0.92

11 11 4.7e-05 0.0057 17.6 0.3 3 23 616 637 614 637 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00055	0.066	14.2	2.2	1	20	262	281	262	283	0.94
2	11	2.3e-06	0.00027	21.7	0.4	3	23	334	355	332	355	0.93
3	11	0.0078	0.94	10.6	0.1	1	23	361	383	361	383	0.97
4	11	6.2e-07	7.5e-05	23.5	2.5	1	21	390	410	390	411	0.95
5	11	2.7e-06	0.00032	21.5	0.6	2	23	423	444	422	444	0.96
6	11	8.6e-05	0.01	16.8	5.3	1	23	455	477	455	477	0.99
7	11	0.45	54	5.1	0.3	9	23	496	510	494	510	0.90
8	11	1.2e-06	0.00015	22.6	3.0	1	23	516	538	516	538	0.98
9	11	0.0075	0.9	10.7	1.8	1	23	542	564	542	564	0.97
10	11	2.6e-05	0.0031	18.4	0.2	1	21	572	592	572	596	0.92
11	11	4.7e-05	0.0057	17.6	0.3	3	23	616	637	614	637	0.96

Sequence Information

Coding Sequence: atgcttgGTCCCATTGCTGTGAAAACAGCTGATTGGTTGTTTACGAAACCTGTGAATAGTCAGACGCTAGCTAGCGCCATTGTACCCCGTTCGCACGCGATGAGCGCCAGCAAGGAAGCCAAAACGACAGACGCCCCCGAGGCGAaccccgcccccgcccttagCAGCGACGGCAGCCCAATGATCAAAATTTTGGACGTGGACGAGATCGTACCACCCAAGGAGAAACGGTCAGGCGCACGCATGAAGCTGCTCAATGACGTAGCCGCCAAGGCTGCCAGCAAGTCCGCCGCCTCGCCCCGACTCAAACAGGAGAAGCGCACCAGCATCAAAATACTCAACAATGATGAATCGGAAAGCAGTCCCAAGGGCGGCGATAGGCGCTCCACGGCCAAAACGCCTAGCGCCGCAGGCAGTGTCAAAATCTTAAACGAGAAACGCATTTCGTCGGCCTCCGCAGCAGTGGAAACGGCTAAAATCAAGACGTCGCCgagcaagaaaaagaaaatggatCACTACGTGCTGCAAGCCATCAAGAGCGAGAACAGCAAAGCGGAGAACACGACTAGCGTGGTGGTGGTCGAGGACGACGACACAATTGACTTCATACTCGCTGACGAAGACGCCGAGCTGGGCGCGGCCAAGGAGAACGGCGATGAGTTTGTAGTCTCCGGTGTCGATGAagaggacgaggacgatgaCGAGGACGAGGGCGAGGCAGCGGGAGAGGGCAGCGCAAATCGCaccagtggcaacaacagcgagcTCAAAGAAATGGTGGAGCACGTATGCGGCAAATGCTACAAGACATTCCGTCGCGTCAAGAGTCTAAAGAAGCATCTGGAGTTCTGCCGCTACGACAGCGGCTATCACCTGCGCAAGGCGGACATGCTAAAGAACCTGGAGAAGATCGAGAAGGATGCGGTCGTCATGGAGAAGAAGGACatctgcttctgctgcagcgAGAGCTACGACACCTTCCATCTGGGCCACATCAACTGCCCGGACTGCCCCAAGTCGTTCAAGACGCAGACCAGCTACGAGCGTCACATCTTTATCACACACTCGGAGTTCAACGATTATCCCTGCTCCATATGCAATGCCAAGCTGCGCAGCGCCGCCCTGCTGAAGCTCcatgagcagcagcaccaactgCGCGGCAAGCCATTCGCCTGCAAGATCTGTGGCAAGGACTTTACGCGCTCATACCACTTGAAGCGCCATCAGAAATACTCGTCGTGCTCGGCCAACGAGAACGACACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTATCGGCTGGACAATCTACGCGCCCATCTTAAGCAGCACCTGGGTACCCAGGTGGTCAAGAAACCGGAGTACATGTGTCATGTCTGCAAAAACTGCTTCTACAGCCTGTCCACGCTCAACATACATATACGCACCCATACGGGTGAGAAGCCCTTCGATTGCGATCTAAACCCTATACCTGCACGGTTTCAATCCTTTGCTGTCAAGGAGGTGCTCAATCGCCACATGAAGCGGCACACCGGCGAGCGTCCACACAAGTGCAACGAGTGCGGCAAGAGCTTCATACAGGCCACACAGCTGCGCACGCATTCCAAGACGCATTTGCGTCCCTACTCCTGCTCGCTGTGCATCCAAAAGTTCAAGACGGAGAAGCAACTTGTGCGACACACCAAGGAGCACACGCGTCAGAAACGACCCTCCTTTGCCTGCACGGAGTGCACACGCAGTTTCCGCACCAGCGCCCTGCTCAAGGAGCACATGGACGCAGGTGACCATTCGCCTGTCAAACCCACACGAGCTAAGCGCTCGGCTAAGATGATCGAGCGCACAGACTGCGCTATTTGCGACAAGAACTTTGACAGCACCGATACACTCAGAAATCACATACGCAACGTCCACGAGTGCAACCCGGATGACATCTTTGGCACTGAGCCACCGGCCAAGCGCAGAGCCAAAAAGACTGTGGCTGTAATGGAGGTGGAGGACGATGATGAGGAGCCAGAGGAAGACTTGACGGGTGCCAACACATCGGCGGGTTCGCTCATCTCCAGCAAGACGGACGGCAATGGAGTTGTGGTGCGCGAATTTATCGTGGATGAGGGTAACGGTACTGCGCAGACAATTGTACTCGAGAATGAAGTGTACACTATTCTGCCTCTGGAGGACGGCGGCGCAACTGAAGCTTCGGGAGAGGACAGCGTCAAAGCAGAGTCCAAggagaaacagcagcaggcggtcTCGCCGGTAGTCAAGAAGGAGCAGCGCAAATCGCTAGCCGCCAGCTTGGCCGCTGCCATTGCGGATAATCTGGAGGAGCCGTCGAGTGATGATGATTTCGGTGGGGAGGTACTCACCGAAGAGGACCTGAAGCTCAAGGAAAACATAGCCAAGCTAATAGACATGTTGGTGGATCCGCAGACACTTAAGAAATATGGATGGCCCAACAGCTCCGAGGAGTCGGTGCTGTGCAAAGTCATCGAGAACTGTGGCCACGATCTGGCCAAGGGCAGCGAGAACTATGCCGAGTTGGACTACGGCAGTCGCATGCGCGAGTACTGCAAGCTGCTGTTCACGGTGGTTATTCACAATGATTCCATAAAGGCGCTGCTCAACAATTTCCCCATAGACGATGTCATTGAGTATGTGCTGGGTGATGAGGATCAGGAGCAGGATCAAGAGACAGAAAAGGGCAAGGACAAGGAGGCCGATAAATCGGATGCGGAAACTAGACAGGACGCCGTTGAAGCCGAGGCTTAG
Protein Sequence: MLGPIAVKTADWLFTKPVNSQTLASAIVPRSHAMSASKEAKTTDAPEANPAPALSSDGSPMIKILDVDEIVPPKEKRSGARMKLLNDVAAKAASKSAASPRLKQEKRTSIKILNNDESESSPKGGDRRSTAKTPSAAGSVKILNEKRISSASAAVETAKIKTSPSKKKKMDHYVLQAIKSENSKAENTTSVVVVEDDDTIDFILADEDAELGAAKENGDEFVVSGVDEEDEDDDEDEGEAAGEGSANRTSGNNSELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSAALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLNPIPARFQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYSCSLCIQKFKTEKQLVRHTKEHTRQKRPSFACTECTRSFRTSALLKEHMDAGDHSPVKPTRAKRSAKMIERTDCAICDKNFDSTDTLRNHIRNVHECNPDDIFGTEPPAKRRAKKTVAVMEVEDDDEEPEEDLTGANTSAGSLISSKTDGNGVVVREFIVDEGNGTAQTIVLENEVYTILPLEDGGATEASGEDSVKAESKEKQQQAVSPVVKKEQRKSLAASLAAAIADNLEEPSSDDDFGGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYGWPNSSEESVLCKVIENCGHDLAKGSENYAELDYGSRMREYCKLLFTVVIHNDSIKALLNNFPIDDVIEYVLGDEDQEQDQETEKGKDKEADKSDAETRQDAVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00495995;
90% Identity: iTF_00541903;
80% Identity: -