Basic Information

Insect: Drosophila mayaguana
Gene Symbol: ftz-f1
Assembly: GCA_037075325.1
Location: JBAMCG010000089.1:303700-312882[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 1.8e+04 -6.5 21.6 40 160 25 153 7 166 0.46

2 3 6.3e-20 5.7e-16 58.9 0.1 1 80 325 403 325 442 0.80

3 3 1.2e-72 1e-68 232.6 0.6 155 409 521 768 495 769 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	1.8e+04	-6.5	21.6	40	160	25	153	7	166	0.46
2	3	6.3e-20	5.7e-16	58.9	0.1	1	80	325	403	325	442	0.80
3	3	1.2e-72	1e-68	232.6	0.6	155	409	521	768	495	769	0.92

Sequence Information

Coding Sequence: atgttaTTAGAAATGGATCCCCAGCAGGCGACAGTACAGTTCATATCATCGCTGAATCTGTCACCGTTTAGCATGCAGCTTGATCAACAGCAGCCGGCGAGTCCCGTGCagagcaacaccaacaacaataacagcagcaacagcggcaacaacaataatagcaataataataataataataatagcaacaacgaTAACGAAACAAATCCTTTAAGCAATTCCGATAACGATTACAGCGCCTATACGCTGCAGTTGGGcaatcatcagcagcagcagcagcaacagcaacagcaacagcagcacctcAATacgcatcatcagcaacagcaacatcaacattaccaacaacaacaacaacagaatatTGCCAGCAACAATGCGAATAGTGCTGCGAACCAATTCAATGCCTCCTcttattcgtatatatacaatttcgaTTCACAGTATATATTTCCGACAGGCTATCAGGAAACCAATTCGTCCCATTCACAGCAAAGCGGCAACGGCACCGGCGTAGCATCAGGCAACGCTGGTCAGCTGCTGAACGGTGGCAGCAATAGCTCTGCCGGCAACGGCTATATGTTGCTGCCACCTGGTGGCACCTCAGCTGTACACATGGCCGGCAATGTCGGTGGCACCGGAGCAGCAGGTGGAGCTGGCAGTGTCGCGTCCAcaggtggtgttggtggtggccATCATGGAGGAACTAGCGCCACCTCTGGCGGAGGCGAAGCCATCGACTTCAAACACTTGTTCGAGGAACTGTGCCCTGTCTGCGGCGATAAGGTGAGCGGATATCACTACGGCCTGCTTACCTGTGAGTCCTGCAAGGGCTTCTTCAAGCGGACcgtgcaaaacaaaaaggtGTACACATGCGTTGCGGAACGCTCCTGCCACATCGATAAAACGCAGCGCAAACGTTGTCCATACTGCCGATTCCAAAAGTGCCTCGAAGTTGGCATGAAACTCGAAGCGGTTCGAGCAGATCGTATGCGTGGAGGCCGTAATAAGTTTGGACCCATGTACAAAAGGGATCGAGCGCGCAAGCTTCAGGTGATGCGACAACGGCAACTGGCCCTGCAGGCGCTGCGGAGCTCTATAGGTTCAGATATAAAGCCAACGCCACTCTCACCTGGCTATCAGCAAACATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGGTATCCTCACTCACGCAGTCGCCGGACTCATCGCCCAgtcccattgccattgctttgGGTCAAGTGAATGCTGGAGCTGGTGGTGTGATAGCCACGCCCCTGAATGTTGGCAATCTGAGTGGCGGCAGCTCGCTAGgtaatggcaacagcaacaccaacaacaatagcacaGGAAGTGCTGGCGGGGGCAGTGGGGGTGGCAATAACGCTGGCAGCGGAAGtggcgccagcaacagcaacaacatcccCGATGGCCTGCAACGTAATGGAAATGgtggcaatagcaacagtaacagcagctgccatgAAGCCGGGAATGGATCTCTGCAGAACACAGCTGAATCGAAATTGTGcttCGATTCTGGCACACATCCATCGAGCACAGGGGACGCGGTAATTGAGCCCCTGAGGGTCTCGCCAATGATACGAGAGTTTGTGCAATCAATCGATGATCGGGAATGGCAGACTCAGCTTTTTGCGCTACTGCAAAAGCAGACATATAACCAAGTTGAAGTTGATCTCTTTGAGTTGATGTGCAAAGTGCTGGATCAAAACCTCTTCTCACAAGTGGATTGGGCAAGGAACACGGTCTTCTTTAAGGACTTAAAGGTGGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCGGACATGCTTGTACTGGATCATCTGCATCATCGCATACACAACGGTTTGCCAGATGAAACGCAACTTAATAACGGACAGGTGTTTAACCTAATGAGCCTTGGTCTGCTGGGAGTGCCACAGTTGGGCGACTACTTTAATGAGTTGCAAAACAAGCTGCAGGACCTGAAGTTCGATATGGGAGACTATGTGTGCATGAAATTCCTAATACTTTTAAATCCAGATGTACGTGGAATAGTGAACAAAAAGACCGTTGTGGAGGGACACGAGAATGTTCAGGCAGCTTTGCTAGATTACACACTTACGTGTTACCCCTCAGTAAATGACAAATTTAGGAGGCTTTTGAATATACTACCGGAAATTCATGCCATGGCCGCGCGCGGCGAAGAACATCTATACTCAAAACATTGTGCGGGCAGCGCACCAACGCAGACGCTGCTCATGGAGATGCTGCATGCTAAGCGAAAGGGGTGA
Protein Sequence: MLLEMDPQQATVQFISSLNLSPFSMQLDQQQPASPVQSNTNNNNSSNSGNNNNSNNNNNNNSNNDNETNPLSNSDNDYSAYTLQLGNHQQQQQQQQQQQQHLNTHHQQQQHQHYQQQQQQNIASNNANSAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSGNGTGVASGNAGQLLNGGSNSSAGNGYMLLPPGGTSAVHMAGNVGGTGAAGGAGSVASTGGVGGGHHGGTSATSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGSDIKPTPLSPGYQQTYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNAGAGGVIATPLNVGNLSGGSSLGNGNSNTNNNSTGSAGGGSGGGNNAGSGSGASNSNNIPDGLQRNGNGGNSNSNSSCHEAGNGSLQNTAESKLCFDSGTHPSSTGDAVIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVVEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479510;
90% Identity: iTF_00532403;
80% Identity: iTF_00540422;