Basic Information

Insect: Drosophila mayaguana
Gene Symbol: Hr39_1
Assembly: GCA_037075325.1
Location: JBAMCG010000121.1:912543-917761[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 1.8e+04 -10.6 23.8 45 153 188 312 166 327 0.33

2 3 0.074 6.7e+02 -0.6 5.0 52 171 281 400 270 407 0.84

3 3 9e-102 8.2e-98 328.5 10.1 1 408 484 858 484 858 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	1.8e+04	-10.6	23.8	45	153	188	312	166	327	0.33
2	3	0.074	6.7e+02	-0.6	5.0	52	171	281	400	270	407	0.84
3	3	9e-102	8.2e-98	328.5	10.1	1	408	484	858	484	858	0.88

Sequence Information

Coding Sequence: ATGCCCAATATGTCGAGCATTAAGACGGAGCAAAGCGTTTCTCCAGGTGCCAGCGGCAGCTATCAGCTGCCCGTGAACATGTCCACGCCCACTGGGCGTCACAATGTCTCCGTGACGAACATCAAGTGTGAGCTGGACGAGCTGCCCACGCCGAATGGGAACCTGGTACCGGTGATGGCCAGCtacaataatcataatcacaATCATAGTAATCACAACAATCACAATCATGGCCTGCGCATACCGCtgggaggaggaggcggcggcgaCAACAGCAAGGAGGAGGACGAATCCGATTCGGAAGCGGAGCTGGCCAACATTGAGAATCTGAAGGTGCGTAGACGTGCGGCCGACAAGAACGGACCACGTCCCATGTCCTGGGAGGGCGAACTGAGCGACGCCGAGGCGAACGGCCAGGAGGCGCCCGACGAGGAGCTCATGGAAACGGAGACGGTTGTGAAGAGTGAGTCGGGCAGTGCTGCCGGAGGCGTGGTCACGGCCATGCTGCAGCCCATCAAAACGGAGCTGGAGCACATAGCCGGCGAGATGCaccagcgacaacagcaacaacagcaacagcaacagcaacagcagcaacagcagcagcagcaactgcaacagcagctgcagagccacaagcagcagcagagctacaAGCTGAAGCTGGCGCCCACCCAAAGTGATCCGATTAATCTGAAATATGAACCAGTTGCCACATCCAATTCGACAACGTCGCTCTGCGATCGCAGCAAGTCGAGCAGCGGCGGCcacctgccgctgctgcccgcCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTACACGCACAGCAgtccgtcgcagtcgccgctgACGTCACGGCACGCCCCCTACACGCCGTCGCTGAGCCGGAATAATAGCGATGCGtcgcacagcagctgctacagctacagctcagAGTTCAGTCCCACCCACTCGCCGATTCAGGCGCGTCATGCGCCGCCCGCCGGCTCCGCCCTCTTTCCGGGCCATGCCAATGGCGGCGCCGGCGTCGGCGCTGGAACACTGCATCATCATAGCGTGCTGTATCCGCCATTGAATGTGGATgctgccgcagcggcagcggcagcggctgccgcGCAGGAAGCGCAAAATCTCAGCAtggatggcagcagcagcagcagcggcgccctGGATGCCTCGGCCACGCTGCCAGCCTCGCCGGCGGGCATCTCGCGGCAGCAGCTCATCAATTCGCCCTGTCCGATTTGCGGCGATAAGATCAGCGGCTTCCACTACGGCATCTTCTCCTGTGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAGaactatgtgtgcgtgcgcggcGGCCCCTGCCAGGTGAGCATATCCACGCGCAAGAAGTGCCCGGCCTGCCGGTTCGAGAAGTGCCTGCAGAAGGGCATGAAACTGGAGGCCATACGCGAGGATCGCACACGCGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTGCCCAATTCGATGCTCAGTCCGCTGTTGAGTCCCGATCAGgcggctgccgcagcagctgctgccgccgtccaacagcaacaacagcagcagcagcagcagcagcatcaacaacagcccCAGCCACATAATCCACTCAATGGCTTTGGCAGCGGGTCCAATTCGCTGCCCGCAAGTCCCAGTCTCGGCGCACCCATCAAGACGGAGCAAACTGATTCGCTCAGTCATCATGCATCGTCGCGAGCCTCAAGCATTCCAGCCCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAATTGGCGCGTATCAATCAGCCGCTGTCCTCGTTTGCATCCGGCGGCTCCTCGTCGAGCGGCACGGGTGGCGGTTCAAGTTCCGCCGGACAGCACACAGCGAACGCACAACAGATGACCAATCCACTGCTGGCCAGTGCGGGTCTCTCCTCTAATGGCGAGAACGCCAATCCCGACCTGATTGCCCATCTCTGCAATGTGGCCGATCATCGGCTCTACAAGATTGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAATATCTCGATCGACGATCAGATTTGCCTGCTCATCAATTCGTGGTGTGAACTGCTGCTCTTCTCCTGCTGTTTTCGTTCCATTGACACGCCTGGCGAGATCAAGATGTCGCAGGGCCGCAAGATAACGCTGGCACAGGCCAAAACAAATGGCTTACAGGCCTGCATTGAGCGCATGCTGAATCTGACGGATCATTTGCGACGCCTGCGCGTGGATCGCTATGAATATGTTGCCATGAAGGTGATTGTGCTGCTGCAATCGGATACCACGGAGCTGCATGAGGCGGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGCTCTGCAGGCGTACACGCTGGCCCATTATCCCGATACGCCGTCCAAATTTggggagctgctgctgcgcatacCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAGATGCTGACGATAAAGACGCGCGACGGTGcagatttcaatttgctgaTGGAGCTGCTGCGCGGAGAGCATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPVNMSTPTGRHNVSVTNIKCELDELPTPNGNLVPVMASYNNHNHNHSNHNNHNHGLRIPLGGGGGGDNSKEEDESDSEAELANIENLKVRRRAADKNGPRPMSWEGELSDAEANGQEAPDEELMETETVVKSESGSAAGGVVTAMLQPIKTELEHIAGEMHQRQQQQQQQQQQQQQQQQQQLQQQLQSHKQQQSYKLKLAPTQSDPINLKYEPVATSNSTTSLCDRSKSSSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGSALFPGHANGGAGVGAGTLHHHSVLYPPLNVDAAAAAAAAAAAQEAQNLSMDGSSSSSGALDASATLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVQQQQQQQQQQQHQQQPQPHNPLNGFGSGSNSLPASPSLGAPIKTEQTDSLSHHASSRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFASGGSSSSGTGGGSSSAGQHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQALQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479509;
90% Identity: iTF_00493681;
80% Identity: iTF_00540417;