Dmau000973.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mauritiana
Gene Symbol
-
Assembly
GCA_004382145.1
Location
NC:8324433-8333882[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.009 0.55 10.4 0.3 1 23 1267 1290 1267 1290 0.95
2 13 6.4 3.9e+02 1.5 0.2 1 23 1437 1459 1437 1459 0.91
3 13 0.00014 0.0088 16.1 2.7 2 23 1462 1483 1462 1483 0.97
4 13 5.5e-05 0.0034 17.4 0.2 3 23 1491 1511 1489 1511 0.98
5 13 4.6e-07 2.8e-05 23.9 4.1 2 23 1518 1539 1517 1539 0.97
6 13 4.4 2.7e+02 2.0 0.4 5 23 1552 1570 1550 1570 0.96
7 13 1.1 66 3.9 5.4 3 23 1577 1598 1575 1598 0.93
8 13 0.12 7.1 6.9 0.2 2 23 1609 1629 1608 1629 0.96
9 13 0.00012 0.0072 16.4 0.3 1 19 1635 1653 1635 1657 0.95
10 13 2.8e-05 0.0017 18.3 0.4 1 23 1665 1687 1665 1687 0.98
11 13 8.3e-05 0.0051 16.8 7.6 1 23 1693 1715 1693 1716 0.96
12 13 0.00018 0.011 15.8 6.5 1 23 1721 1743 1721 1743 0.98
13 13 0.0021 0.13 12.4 6.1 1 23 1749 1771 1749 1772 0.96

Sequence Information

Coding Sequence
ATGGTCGACAACAGTGTCCAATGCCCCGTGTGCACATTGTACCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACCCATCCCAAGGAGCAGGTGATCAAGGCGCTGGTGCAGATGACGATCGTTGGGAACGGTGGCAACAGCATGGGCAGCGTTCTTGCTGCCGCCATGCTGACAGGAGGAACTGGAGGAGGTGGATCCAGCGGCGGCGAAGCCAGTGCTGATGAGAAACCGGCCGTCTCATCACCACCGTCTGGCGGCGATGTCAAGCCAGTCGTGGCCAATACCatatcagcagcaacagcgccTGTGCtgccaccagcaccaccaccgcTATCCTCCTCCCTCGTGGCGGCCTGCTCCAACGGAGCCGCCTCTTCGACAACCAGCTCCACACCCACCTCCACCTCAgcaagcaacagcagcagcctcagcagcagcaaaccGAGCAATCCACCGATGAAAGCACTGAAATGCTCACCGCCCACAACTGAGGCGCGAGCCAGCACATCCGCACATCCCACCACGAGCAGCGTGTCCACTTTGTACCAGCCAGCGCAGGTCACTCCGGATTACCGCTTCAACCAGCAGCCACAGACGACGGGCTTTGGGCGTGGTGTCACCACCTCAGCAGCCGGTCTGGTGATTCCGCAGGTGCCTCAGCAGCACTTCCTCGCCAGCCATCAACAGCAGGCTCACTTTCCACACCAGCAGCAGCCcccgcagcaacagcaacagcatccGCAGCATCAGCCTGCTCTGAAGTTCAGCTACGCCACAGCTTTGCCCCCACCTCCGCCGTTGCAGCTTTttacgcagcagcagcaacagcagacgGGTGTTCCACCGCAGACCCAGCAGCAATCGCACCAGAAACCACCTCCCGCCTATGGAGCCGCCATTAGTCAAATCCGATCTCAGCACAACCAAAACAAACAGCAGCCACAGTCCCAAAGCGTGGCTATGCAACACAGCCTAGCCCTGGCACCAACGACGACATCAGCGGCTTCAACTTCACACGCAACTGCAGCTGTCAAGCAGCCCAGTAAACCGCAAACGGAAGTATTCCTGAATCCCCCACCACCGCCATCGGCACAGCAACAGTTGCAGATCCACAATTTAGTGCAAACTCAAGGTCAACACCATCAGCATCCTCAccagcagcagtcgcagccGAGCCAGCAGAGTCACCAACAGCCACCGAGCTTGCAGACCTACGGATTAGGGGTCAGCAGTAGCTGCAGTTCCTCCAACAACCCCTCGACATCGGGATCTGGTCATCGTGCGAATCGTCAGACAAACTCACCGTTTGGAGCACTGCTAAATGCTGCAGCGGCTGTGGCCTGCGCATCGCCGGCCTGTCCCACCACCGCATCTTCGGTATTGAGGTTTGCAGAATCACCGGTGGCACACTACCTTGAGCGGGAAAATGGTGACTTCATTGTCCAGGAGACACCGAAGCATATCGTAGAGTGTGTGGAGAAGGAAGACGGCGAGTTTTCCGTGATCGAGCGCATTTATCAATCCCCGCCGAGTGTTCTGCACATacacgatgatgatgaggatgacgaggatgaagaggaggaggacgagcaTGAAGTTCCGCCCGAGGAAGAAGACGGTGACGATGAGCGGGAGGAGAACAGCCACAGCCGTAATATGAGCAAGACAACGAAAAAGGCCCGTAAGACGAAGCCGAAGCGCGGCTCCAAGCGCATGTCGGACGAGGAGGAGTTCATGAGCCTGAGCAGCGGATGTGAGAGTGAGTTGGAAAAAGAGCGTAAGCAGGAGCAGCTAAATGCGGCGGCATCACTACCACCTCCATTGTGCACGGCTCCTTCTACGAgcgctgctgctggagcttCCACCTCCAATCTGGCGGACAATCATTCCAATTCCGCGTCCAACTCCGCCTCCAATTCGAACTCCACCGCCACTACAAAGTCCAAGAAGAATCGAATCACAGTACTCAGCGATGTTCCGCTCAATATGAATGAGTACCTCGATTTGATGGGCAACATCGTAGCCTCCAGTCGCATTGGGGCAAGTCGACCGTTTGCCGCTGTGGCTCCCATACCACTCGTCAAGGTGGAGAAGGAAGAGCCCCTGGATGATTACGACAACGTGGCAATGGCCGCAAATGCCGAGCTGGAGCAAAAGCCCAGCCTTGAGCACGGCACCACCAGCGTCATTCGAATGGCAAGCACGGCTGCTGCGTCGACATCTGCAACGGCGACCGAAACGTCTCCCGAGGATCTCACCCAGCCGCCGCCCATGAAAGTCGAGGTTGAGGCGACCACCACGTTGTTGCCGCAGCGCTTTTCCACTCCCGCCCAGCATCGTGGGCCTAAGAAATTAGTCAtcaaaccaaaacaaacagcACCAGCGACAGCGACGACAACAAAAAAGACTGACACCCCATCTTCCCCCAGCAACAACCCATCCATATCAAGAGATCTGGTGCAAGTAAAGAGTGAGACCCTGGAGGCGCCAGCGACGAGCAGTAGCAGTAGCATTCTGGAGAAGCACCTAACCGCCAGCCGAAAACTATTGCATCATCACTCGGCGGTGAACGATGACGATGCCCGGGTGCTGCTGGAGTTTGCAAACTCCAAGCAGCCGCCGCCACTAGCAGCGTCGAGCACAACGTTTGTGGTTAATGCCAGTGTAGGCTTTCCCTCGGCTGGCTCAGTTTTCgccagcagcagtagcagctgTTCCAAAGCACCGGCCAAGCCGGGAGAGGAGTACATCCTGCCGGACAACAACATGGACGTGGATGAGATTGTGATATCCTCGTCGTCTTCCTACACCTCCACCGCAGCCCAGGTGCAGAACACGTTACAGCCGCCGGACTTTAACTTTCTGTACCACCAGGCCACTACCACGGCTACGACGGCCACATACTTTAATCCCTTCTCCaggcagcagcatcatcatcagcagcagcaacagcacgGCGTCAGCGATGCCACCAATGCGGCCACTTTGGCTTCGTCGTCCAGCAATTCGTTGGACCACGACTCGATGAATGCTACATTCCGGGTGGCCAAGACCCAATCGCTGCAGTCATGGTATCAGCAAGAGCCGGATCACGATCCACAGAATCAGGGTGGTGCGGAATCGGGAACTGCCACTCCCTCCAATCAGAGCCAGGATGTGGTCAGCCACCAGCCAACCAACTTTAACGCCGCCCTAGCGGCCGTCGATTGCTGTAGCGTTGCTTTGGACGAGGATGCAAAATATCTTGATCTAGACGCCTGCAAGCGGGAGCAGCTGAGCAGCAGTAGCAACCTGCCATCCGCTTCCGCGTCCACAACGTCGTCGTCCTTCGCTGGCGCTGGCACGGAAAGCAGTTTGGTGGGTGGTCTGAATATCCGAACCGATGAGAAGATGCCCGCCAAGGGTGAAATCTCCGAACAGGAAAGCAACTGCGACATCGAGAACTCCTGGAGTGAGTCGGTTTATGGGGATATTTCGCAGCGGTACTTCAGAAACCAGTTTTCCGGCGGCTACAACCCTGATTGGCGGCAGGACTATTATCCGGCTCAGGATCTCAGCGCTCAGCAGAGAGAGCAAAAACGTTTTGACTTCAATGCTGTCGATGATGAGGCTTCATCTAGCTCGAGAAGGAGCCATCTTACAGATCTTCTCCCGACAGCGGCCACCTCCTCCGCATGTACGTCATCAGCTTTGCTGGCGGGTCCACCAATAGCTTCGACATCACGGGCTGCTGCTGAGGCGGCAGCGGAGGCGGCTGCTCTTGCCCAGCGGAAGCCGCAGCGCCGCAAGCTCTACAAGTGTCCACACTGCGAGGCGATCTTCGAAAAGCTTAAGGAGCGTAATGCGCACATGATTGGCGAACACAACTACGTGCGGCAAAATCGCCGTCTAATTTGCACTCAGCCGCAAATGAATACTTCGATGTTACCGCCACAGCAACAGATGATTATGCAGGCAGGTGAGGTTGAGGATTCCAAGGATGGCATTGTGAAGATAAAACAGGAGCAATGCCAGGAAAAGCATGATGTTGAGCAAATGCACGACCATTCCGAACTTTTGGCCGATGTCAAGGACTCTGAGCTGATGGGCATCGGCGGTGATGGCGACGGTGATGTAGATGACGACATTAAGCCACCCAACCAGCTAGATGAAAAGCCCACGCTGCCGCCATTAGCCATGACGACCCCAGCGGCTAAATTAGCAGCTTTGTATCGAATGCTCATCGCCTACAACGAATCCAAGCTCGGACAGGAGCGCAACAATCTTAGCGAGCTGGAGCAGAAGGCTATGGAAAAATCCATATTCCTCTGTTATGTCTGTCGTACCGACTTCCCGTCCGTAAAGCTCTATGACGCCCATCTCACCGAGCATCCCGCTGAATGCTTTACTTGCGGCAAGAAGTTCTACCGCTGGAAGAACTTTTCCTTGCACTTAAAGCGGCACTTGGGCTGGAAGGAGTTCGGATGCTATGTCTGCGACAAGAAGTTCGTGGTGCGCAGCGCCTTGGTCGAACACATGCGGATGCACACGGGGCAAACGCCACTCAAGTGCAAGATATGCGGTAAAAAGTTCAAGCGATACTCGAATCTGACGCAACACCGCAAACGCCACACCAAAATGATGGTGCGCAAAAAGGAGTACGTGTGTCACTGCGGCGAAGTCTTGCCCTCGAAGGCTCGCTTCCTGTGGCACAAGGAAACGCACGACCTGAAGCCGAAGTGCTGCCCGTACTGCTGCGATCGGTTTGTGCACGCCAACTCGCTACGTCGACACATACGGCTGGCCCACTCTGATAAGTTTGACTATGCCGAACCTATGGAATGTCCGATGTGTAAGCAAATCTTCGCGAAGACGTCCATCAAGGCGCATATGGCGACGCATTCAACGGAGCCCCAATACGATTGCGCCATTTGTAGCAAGAGCTTCTCCACCAAATGGAATCTCAAGATCCACTCGTGGGTACACGCCAACCGGACGGCCAAGCCCTTTAAGTGCGAATACTGCCCAAAGGCGTTCGTGCGAGAGTTGGACTTCAAGAACCACATCAACGCGCACAAACAGATCAAACCGTACACGTGCGAGTACTGCGGCTGCAAGTTCATCCGCAAGTACAATTACATGCGACACCGGCGCGAACATCATGGCACCAAGAAGTTCACCTGCGACCAGTGCGATAAGTCCTTCCATCGGCATTACTATCTGATAGAGCACCGGCGAATGCATACCGGAGAGCGTCCGTTCACGTGCACCATCTGCGGCAAGAGCTCCACAACTAAGACCAACCACAACAAGCATCTGAAGATCCACCATTCGCGCGATCCCTTCACGGTGGAGGTCTAA
Protein Sequence
MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNGGNSMGSVLAAAMLTGGTGGGGSSGGEASADEKPAVSSPPSGGDVKPVVANTISAATAPVLPPAPPPLSSSLVAACSNGAASSTTSSTPTSTSASNSSSLSSSKPSNPPMKALKCSPPTTEARASTSAHPTTSSVSTLYQPAQVTPDYRFNQQPQTTGFGRGVTTSAAGLVIPQVPQQHFLASHQQQAHFPHQQQPPQQQQQHPQHQPALKFSYATALPPPPPLQLFTQQQQQQTGVPPQTQQQSHQKPPPAYGAAISQIRSQHNQNKQQPQSQSVAMQHSLALAPTTTSAASTSHATAAVKQPSKPQTEVFLNPPPPPSAQQQLQIHNLVQTQGQHHQHPHQQQSQPSQQSHQQPPSLQTYGLGVSSSCSSSNNPSTSGSGHRANRQTNSPFGALLNAAAAVACASPACPTTASSVLRFAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEDEEEEDEHEVPPEEEDGDDEREENSHSRNMSKTTKKARKTKPKRGSKRMSDEEEFMSLSSGCESELEKERKQEQLNAAASLPPPLCTAPSTSAAAGASTSNLADNHSNSASNSASNSNSTATTKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGASRPFAAVAPIPLVKVEKEEPLDDYDNVAMAANAELEQKPSLEHGTTSVIRMASTAAASTSATATETSPEDLTQPPPMKVEVEATTTLLPQRFSTPAQHRGPKKLVIKPKQTAPATATTTKKTDTPSSPSNNPSISRDLVQVKSETLEAPATSSSSSILEKHLTASRKLLHHHSAVNDDDARVLLEFANSKQPPPLAASSTTFVVNASVGFPSAGSVFASSSSSCSKAPAKPGEEYILPDNNMDVDEIVISSSSSYTSTAAQVQNTLQPPDFNFLYHQATTTATTATYFNPFSRQQHHHQQQQQHGVSDATNAATLASSSSNSLDHDSMNATFRVAKTQSLQSWYQQEPDHDPQNQGGAESGTATPSNQSQDVVSHQPTNFNAALAAVDCCSVALDEDAKYLDLDACKREQLSSSSNLPSASASTTSSSFAGAGTESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSESVYGDISQRYFRNQFSGGYNPDWRQDYYPAQDLSAQQREQKRFDFNAVDDEASSSSRRSHLTDLLPTAATSSACTSSALLAGPPIASTSRAAAEAAAEAAALAQRKPQRRKLYKCPHCEAIFEKLKERNAHMIGEHNYVRQNRRLICTQPQMNTSMLPPQQQMIMQAGEVEDSKDGIVKIKQEQCQEKHDVEQMHDHSELLADVKDSELMGIGGDGDGDVDDDIKPPNQLDEKPTLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTEPQYDCAICSKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00529734;
90% Identity
iTF_00591878;
80% Identity
-