Basic Information

Insect: Drosophila lutescens
Gene Symbol: -
Assembly: GCA_037075285.1
Location: JBAMCF010001083.1:1726923-1732753[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0015 0.12 13.2 0.4 1 23 140 162 140 162 0.97

2 14 3.1e-05 0.0025 18.5 2.7 1 23 369 391 369 391 0.98

3 14 1.8 1.5e+02 3.5 1.7 1 23 397 420 397 421 0.91

4 14 0.23 18 6.3 0.3 1 23 442 465 442 465 0.92

5 14 0.0012 0.098 13.4 1.9 3 23 728 748 727 748 0.92

6 14 0.048 3.9 8.4 1.4 1 23 754 777 754 777 0.98

7 14 1.5 1.2e+02 3.7 1.5 2 23 814 835 813 836 0.91

8 14 0.0025 0.2 12.4 0.6 1 23 857 880 857 880 0.97

9 14 0.0019 0.15 12.8 0.4 1 23 1088 1111 1088 1111 0.92

10 14 0.0016 0.13 13.0 4.1 1 23 1123 1145 1123 1145 0.98

11 14 1.1e-05 0.00088 19.9 1.6 2 23 1151 1173 1150 1173 0.96

12 14 0.0029 0.23 12.2 3.6 2 23 1180 1204 1179 1204 0.93

13 14 0.11 9.2 7.2 1.5 1 23 1209 1231 1209 1231 0.96

14 14 0.0034 0.27 12.0 0.5 1 23 1237 1260 1237 1260 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0015	0.12	13.2	0.4	1	23	140	162	140	162	0.97
2	14	3.1e-05	0.0025	18.5	2.7	1	23	369	391	369	391	0.98
3	14	1.8	1.5e+02	3.5	1.7	1	23	397	420	397	421	0.91
4	14	0.23	18	6.3	0.3	1	23	442	465	442	465	0.92
5	14	0.0012	0.098	13.4	1.9	3	23	728	748	727	748	0.92
6	14	0.048	3.9	8.4	1.4	1	23	754	777	754	777	0.98
7	14	1.5	1.2e+02	3.7	1.5	2	23	814	835	813	836	0.91
8	14	0.0025	0.2	12.4	0.6	1	23	857	880	857	880	0.97
9	14	0.0019	0.15	12.8	0.4	1	23	1088	1111	1088	1111	0.92
10	14	0.0016	0.13	13.0	4.1	1	23	1123	1145	1123	1145	0.98
11	14	1.1e-05	0.00088	19.9	1.6	2	23	1151	1173	1150	1173	0.96
12	14	0.0029	0.23	12.2	3.6	2	23	1180	1204	1179	1204	0.93
13	14	0.11	9.2	7.2	1.5	1	23	1209	1231	1209	1231	0.96
14	14	0.0034	0.27	12.0	0.5	1	23	1237	1260	1237	1260	0.95

Sequence Information

Coding Sequence: ATGGCGCTGAACAAGAGGAACAGCTCCCATTCGGACGCAATTTCGGGCGCCGAGGTGGTGGACTACAAGTTTTCGTGTCGCTGCTGCTTGAAGACGGACGTGGAGTATCTCAAGCTGGACTCGGTGGCGGTGGCCCGCAGCCTGGATCCGGCGGACGCCGCGGACAAGATTCCGCTCCTCCGTTGCCTGCTCTTCTGCGTGAGTGCCGAGAACGCCCCCGAGCTGCCGCAATACATCTGCATCGAGTGCAGCAAGAGCCTGCAAGTGGCCTACTATTTCCTCAAGAATGCACTGCGTGCCCACGAGATCCTGTGTCGAAAATTGTGTCCCAAGAGGGCCGCGAGGAGACTTAATGGCTCTTTGGTTCAGGAACCGCAAAAACCAGACCGAGAAGAGAAGCCTTTGAAAACCATGCGGCACGAGTGCCAGGTCTGCGGAGTGGTGGTCTACAATCGCCTGGAGCTCAAGCAGCACATACGACAACATGCAGAGGGCCTTTCGTACAACTGCAAGTTCTGCAGCTTCACCACGCTGAAACAGCGCATACTGCTGGAGCACTATGTAACCATTCATGCCCTGTCCACTGGCCAAGCGGAGGAGCACATCAAGTCGAGGGATTTGCCAGCGCACGAAGAGGAAGAATCCAAGGCGGTGTGCACGCTGGAGGACATGGAGCTGCTAATACCCACTGTTCTGACACCGGAGGACTACGCACAGCCCCAGCCGCATATTGATTCCGATCAGCTGCGCGACATCGAGCGGCAGCTGGCCGTCAGCATGGGCGAGACGGCGCCGGCGGTGGACACTCTTACCTCCACCTTGCCGCCCATGGACACGCCCAACGTGAGCATCGGCACTGAGTATCTCGTCATGCCCGATGGCTCGCTGCAGCCAGTCAATGGAAGCGGCGTGGTCATAGAGTATATCGATGACAGCAAGCCGAACAATCCCTCCAATGTCAATATCAGCCTACACAATCTCCTGTCCGCCAATGAGCAAGGTGAACCGATGGATATTGATGTCAGCGAGCTGATTGTGGAGGAAACGATGCCGCAGATAAGGGTCAAGCCAAGACCAACAGCTGGCGGATCGCCCAATTACAAGCACAAGTGCAAAGTGTGTCCAAAGACATTTTCCACTGTGGCGCGCCTCAAATCTCACCAGTTGACCCACAGCAATTTGCCCAAGTTCTTCTGCGACCAGTGCGACTTTTACTCGCTGCGCAGTGCCGATCTCATCCAGCACTACAAGATGGTCCACCATCGGTCCGATGAGAACGGCAGGAGCGACAAGGACCCAACGAAGGCGGAGGAGTCACGTGTCTTCTCGTGCGACATGTGCCTCTTCGAGACGGGCACCGCCAGTCAGTTGCGGACGCACTACACGGAGGGCCACACGATCCAGCCCACGGAGGTTCAGTTGCGTCCTAGTTGGACCGCTGAGGAGGGAGCAAACATTCCCCAAAACCCCGCATCGATCGGCGTTGCTCCCAAGAAGCTGACGCCGGTCAGGAAATCAGATCACACCGACATCCCAGTGGGCATTAAATACCCGCCAGTTGTGGTGGAAGCACAGGTACCAGTGCACCAGCCCGCGCCAATGGCCACCACATCAACGACCATCACGGAAACAGGCGACATCAACGTGGTGGTGGATGCTACCCCGCTGTTCTATGCGGCAACCTCCACCGTGACAACCAACCCAGACCCAGTGACAACGGTGGTGGAACCATCAACCGGGGAAGCCGACAGCAATGCATTCGGAATCTTTCCCGAAATCCCAGAGAGCAATCTGTCCGTAAACGAGGCCGTTCCGCAAGTGGCAGCCAATACTTCCAACATTTCGATGTTTGGCGACATGCAGGATTTCATCGACAATACCGACGTAGCCGCCATATGCACCATACCCGCGGATGATATGCCCGTGGTGGATGGTGATGATATTGTGATCGATAACAATAATATCAGTCTGGACTTTGATGCCGAGAATTTGTTCGAGGAtttcgaggaggaggaggatgcgGTGggcgaagaggaggaggaggaagaggacgAGGCGGACAACGATGACGAGAATGACAACAATGATGCTGCCACGGATCAAAATTTGCTGCTAACCAGCGACGACGATGATGTGGACGACTTTGATGACGAGCAATCAAAGCATCTGCAGAAGCCTTACTGCATTTACTGCAACAAGAAGTTCACCAGCCAGTATAAATTCGAGAACCACATGTTTGTCCATCGGGGCCTGGCCCCCTATCGCTGTGAGCTGTGTACGAACCTATACAACATGAAgcgtttgctgatcaggcacTATAAAACTGTGCACAAGCGAATGCCTACGAGGGACATGGTCCAGGCCAAAGGCGATAAGGTTTCCGTAGCCCGGACCAACATCGAGAAAATCTATCTTGGCAAACTGAAGAAACCAATGCTCATGTGCGCTAAATGTCCGTTCGAGTGCGACTCAGATGCGGATATGAGGAAACATCTGAATGCCCATCACGGCATTAATGACGGAGTGTCCGTCCATGCCAACGAAGTGTTTATTATACGCAAACTACCATTCGAATGCCCGCGCTGCATTCGATCTTTTGCGGCCAAAAGCACCCTCAGTCGCCACCTGCAGCGCAGCCACTTGGTGGACACGATTATAGAGATGCAAACGCCGCAATCGGTGGAAAGCACCACAGTAACCCTGGCCACATCGTCGTCAACAAGCCCCGGGCCAGAGAACCCGGTCTTGGAGGCAAACCAACATAATGAGATGATGCAGACGGACGGTGGGGCTGAGAGGATGGCAACGGCAGCGTCAGGCATTGGCGGTGGCAATGAAGTAGCAGGCAAAGATGAAGGATCAGGAAAGAATGGAAAAATGGATCCGGCAGTGCCAGAGGAAGAACTTGATCCAGTGACATTAGACGCAGCCACAGCGGTGACTACAACAGcaatagcagcagcaataacggcggctgcagcagcggcagctacATTGTCCGAATCGCCCATCACAACCACATCCTCATCGACAAACTCCACCCTCTTCCCCACACCCACACCGTTTGACTACGAATATGATTTTATGGGAGATGCAGCCCAGCGATCCACGGCCAATCCCCATGCCATTTCCAAAGCTACCACTAATGCCCCACCTAGCAGTTTGCTCAACGGCAGCGACAAACTGTTGACCACCGCTGCCCTAGCTGCATCGCCAGTGAAGGGTCTGCGCTCCAACTCCCGTCTGCTTCGCACTTCCACCTACATGTGCAAGCTGTGCAACAAGACCTTCGACGAGCTGGGCAAGCTGGTCAAACACGAAATGGACCTGCACTCCAATACTGAACCATCGCGGTGGGGCTACCAACACAAGTGTCCCATCTGCAATACAACGTACCGAACGCTCACTCTTCTGAAGTTCCATATGAAGCGGCACGGCGGCCGGAAATCACAGTGCAAACTGTGCCCCAAAACCTTTGTGACCAACACGGAGCTGGAGCGGCACACGAAGTCTAAGCACGGCAAGGAGAAGACGCTACGATGTACGCTGGATGGCTGCCGGAAGACGTTCGCCTTCAAGCATCATTTGGTGCGACATCAGAACGCCACGCATTTAAACACGCGGCATATATGCCCCGTTTGCAAAGAGGAGATGCAGTCCAGTCTACATCTGAGGAACCATATGAGCGTGCATAAGAGCTCTCTGACCTACAAGTGTCCCAAGTGCGACCGCTCCTATTTGCGGCGTGGAAGACTCACAAGCCATGCTCTCATGATCCACAAGATCCGGCTTACCACAGAAGAGTTGGCTGACATCTCTTCACAGTCTGGGGGCCTTACCAATCCGCATGATCTGAAGGAAATGACGACCAGGGGGCCAAGTCCCTGTTGCAATAAGGATGTCGATGGCGAAAAGGAAATAAAGGACGAGCCGGCAGCTGCAGCCGATAATTCCAAATAG
Protein Sequence: MALNKRNSSHSDAISGAEVVDYKFSCRCCLKTDVEYLKLDSVAVARSLDPADAADKIPLLRCLLFCVSAENAPELPQYICIECSKSLQVAYYFLKNALRAHEILCRKLCPKRAARRLNGSLVQEPQKPDREEKPLKTMRHECQVCGVVVYNRLELKQHIRQHAEGLSYNCKFCSFTTLKQRILLEHYVTIHALSTGQAEEHIKSRDLPAHEEEESKAVCTLEDMELLIPTVLTPEDYAQPQPHIDSDQLRDIERQLAVSMGETAPAVDTLTSTLPPMDTPNVSIGTEYLVMPDGSLQPVNGSGVVIEYIDDSKPNNPSNVNISLHNLLSANEQGEPMDIDVSELIVEETMPQIRVKPRPTAGGSPNYKHKCKVCPKTFSTVARLKSHQLTHSNLPKFFCDQCDFYSLRSADLIQHYKMVHHRSDENGRSDKDPTKAEESRVFSCDMCLFETGTASQLRTHYTEGHTIQPTEVQLRPSWTAEEGANIPQNPASIGVAPKKLTPVRKSDHTDIPVGIKYPPVVVEAQVPVHQPAPMATTSTTITETGDINVVVDATPLFYAATSTVTTNPDPVTTVVEPSTGEADSNAFGIFPEIPESNLSVNEAVPQVAANTSNISMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEEEEDAVGEEEEEEEDEADNDDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTNIEKIYLGKLKKPMLMCAKCPFECDSDADMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKSTLSRHLQRSHLVDTIIEMQTPQSVESTTVTLATSSSTSPGPENPVLEANQHNEMMQTDGGAERMATAASGIGGGNEVAGKDEGSGKNGKMDPAVPEEELDPVTLDAATAVTTTAIAAAITAAAAAAATLSESPITTTSSSTNSTLFPTPTPFDYEYDFMGDAAQRSTANPHAISKATTNAPPSSLLNGSDKLLTTAALAASPVKGLRSNSRLLRTSTYMCKLCNKTFDELGKLVKHEMDLHSNTEPSRWGYQHKCPICNTTYRTLTLLKFHMKRHGGRKSQCKLCPKTFVTNTELERHTKSKHGKEKTLRCTLDGCRKTFAFKHHLVRHQNATHLNTRHICPVCKEEMQSSLHLRNHMSVHKSSLTYKCPKCDRSYLRRGRLTSHALMIHKIRLTTEELADISSQSGGLTNPHDLKEMTTRGPSPCCNKDVDGEKEIKDEPAAAADNSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605810;
90% Identity: iTF_00578770; iTF_00581758;
80% Identity: -