Basic Information

Insect: Drosophila lutescens
Gene Symbol: -
Assembly: GCA_037075285.1
Location: JBAMCF010000681.1:43988-48506[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0011 0.085 13.6 0.8 1 23 208 230 208 230 0.96

2 25 2.7 2.1e+02 2.9 3.3 1 20 236 255 236 258 0.80

3 25 0.0032 0.26 12.1 1.4 3 23 291 311 289 311 0.97

4 25 0.00012 0.0097 16.6 1.2 1 23 384 407 384 407 0.94

5 25 0.17 14 6.7 1.3 1 23 448 470 448 470 0.98

6 25 0.046 3.7 8.5 0.0 2 23 483 504 482 504 0.96

7 25 0.3 24 5.9 0.3 1 23 579 602 579 602 0.97

8 25 0.005 0.4 11.5 1.6 3 21 613 631 611 632 0.95

9 25 0.11 9 7.2 5.0 1 23 641 663 641 664 0.95

10 25 0.00083 0.067 14.0 1.5 2 23 677 698 676 698 0.97

11 25 0.00027 0.022 15.5 7.1 1 23 706 728 706 728 0.97

12 25 0.028 2.3 9.1 0.2 1 23 866 889 866 889 0.94

13 25 0.29 24 5.9 4.6 2 23 897 920 896 920 0.91

14 25 0.0097 0.78 10.6 1.0 1 23 926 949 926 949 0.94

15 25 6.4e-05 0.0052 17.5 2.0 2 23 968 989 967 989 0.97

16 25 0.00033 0.027 15.2 0.9 1 23 996 1018 996 1018 0.98

17 25 0.2 16 6.5 0.0 2 21 1045 1064 1044 1065 0.92

18 25 0.007 0.57 11.0 4.6 1 23 1115 1138 1115 1138 0.96

19 25 0.72 58 4.7 3.4 1 23 1175 1198 1175 1198 0.94

20 25 0.00079 0.064 14.0 3.0 1 23 1224 1247 1224 1247 0.98

21 25 5.8e-06 0.00047 20.7 0.2 2 23 1273 1294 1272 1294 0.95

22 25 6.1e-05 0.0049 17.5 2.4 1 23 1300 1322 1300 1322 0.99

23 25 2.3e-06 0.00018 22.0 2.0 1 23 1328 1350 1328 1350 0.97

24 25 2e-07 1.6e-05 25.3 2.4 1 23 1356 1378 1356 1378 0.99

25 25 0.00096 0.078 13.7 0.1 1 22 1384 1405 1384 1408 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0011	0.085	13.6	0.8	1	23	208	230	208	230	0.96
2	25	2.7	2.1e+02	2.9	3.3	1	20	236	255	236	258	0.80
3	25	0.0032	0.26	12.1	1.4	3	23	291	311	289	311	0.97
4	25	0.00012	0.0097	16.6	1.2	1	23	384	407	384	407	0.94
5	25	0.17	14	6.7	1.3	1	23	448	470	448	470	0.98
6	25	0.046	3.7	8.5	0.0	2	23	483	504	482	504	0.96
7	25	0.3	24	5.9	0.3	1	23	579	602	579	602	0.97
8	25	0.005	0.4	11.5	1.6	3	21	613	631	611	632	0.95
9	25	0.11	9	7.2	5.0	1	23	641	663	641	664	0.95
10	25	0.00083	0.067	14.0	1.5	2	23	677	698	676	698	0.97
11	25	0.00027	0.022	15.5	7.1	1	23	706	728	706	728	0.97
12	25	0.028	2.3	9.1	0.2	1	23	866	889	866	889	0.94
13	25	0.29	24	5.9	4.6	2	23	897	920	896	920	0.91
14	25	0.0097	0.78	10.6	1.0	1	23	926	949	926	949	0.94
15	25	6.4e-05	0.0052	17.5	2.0	2	23	968	989	967	989	0.97
16	25	0.00033	0.027	15.2	0.9	1	23	996	1018	996	1018	0.98
17	25	0.2	16	6.5	0.0	2	21	1045	1064	1044	1065	0.92
18	25	0.007	0.57	11.0	4.6	1	23	1115	1138	1115	1138	0.96
19	25	0.72	58	4.7	3.4	1	23	1175	1198	1175	1198	0.94
20	25	0.00079	0.064	14.0	3.0	1	23	1224	1247	1224	1247	0.98
21	25	5.8e-06	0.00047	20.7	0.2	2	23	1273	1294	1272	1294	0.95
22	25	6.1e-05	0.0049	17.5	2.4	1	23	1300	1322	1300	1322	0.99
23	25	2.3e-06	0.00018	22.0	2.0	1	23	1328	1350	1328	1350	0.97
24	25	2e-07	1.6e-05	25.3	2.4	1	23	1356	1378	1356	1378	0.99
25	25	0.00096	0.078	13.7	0.1	1	22	1384	1405	1384	1408	0.91

Sequence Information

Coding Sequence: ATGCTTCCCTCGGACATTTGTCGCACCTGTGGCCTGCAAAACAGTCAGTTGCTACCATTGTCCACCTGCCTGGACAGAGACGCCTCCAAAAGTTACTACGATGTGCTCGAGGAACTGACGAAAATCAATACCCAGCTGGAGAGCTCGGATGATAATCTGCCGCAGCATCTGTGCACCGATTGCTGGACGAGATTGGAGAGTGCCTATGCCTTCGTGGAGCAGGCCAAAAGGGTCAAGGGAGAGCTACTGGCTCGCCTCAGGGAATGTCTGGATGAAATGCCCATCGATATTCCCCAGGAGGAGCAGAACATAAAGACCGAGGTGGACCTCGATGACGAGGGCAACAAGTGCGACGAAGTGGAATCCACTGGACTAGCAACTCTCGAGCTCAAGTGGCGGCCTGAAAGTGACAGCGATGAGGACTTTCTTGATGCAGCGGAGAGCGATGAAGATGAGGTGGATAAGAAGACCTATCATCTGCGTCGAAGTTCCCGGAAGGTCAAGCAGGCAGTGGAAAGCGAAGATGAGGAAGTTAAACCACCTGAACCATCGCCCGTCAAACGGCGTCGAGGACGTCCTCCTGGTCCTGCTAAGAGCACGTCGATGACCACCGATGGCCGCCACGCATGCGAGGTGTGCGGAAAGACCTTTTCCTGGTACCGCGACATGCAGCGCCACGCCAGGATTCACTTCGAGCAGGCCTCGTTCGTGTGCGACACCTGTGGCAAGGGATTCTTGCGCAAGGACAAGTACATGTTCCACCTTCGCTGTCACAAAAAGCGCGAGGCCAAGTGGAAGGCTCTCCAGGTGGGCAAGGAATGGCGCTTCGCTGAGCGTCTCTATAGTTCCGGCAGGTTGAAGAAAATCGACTGCAAGTTGTGCGGTTTGAGTTGCCAGCGAATGGAGGAACTTCGAACTCACATTAAGAGTCATGTAAACGTCGAGAGCTTAGACAATTTGAGAAAGGATAGCGATGTGGTCAGGGAGCACTTCCCTGGCTTTCCGTGCGACCTGAACATTATCAAGCAACAGATCTGCGCCGAAATAGCCGAAGGGCATTTTGAGAAGTTTGCCTGCATTGTGAATTTCCACGGCTATGAGTTGGGGCTCAGTGATTCCGATGAAGAGTGTGACAGCAAAGAGTCCAAGTATAATTGCAATGTGTGCAATTTGTCTTTCACCCGGAAATATCGCTTGATTAAGCACACACTGGAGGAGCACTCCCAATCCGACGCTTCAACACTTCCCTGGCAGCGCTGCAGTTCCTGTAAAGTTGGTTTTCTGTGCCTAACACTCTTCAACCAACACGTGAGCAACCATTGCCACAGCAAAATAAAGCGATATCGCTGCCGTAAATGTCCAGGGAAGTTCATGTGGCCGGATAACCTGCAAAACCATGCGTGCTCACATCGCCGCGACGAGGACAAGACGATACCCAAGCAGATGATGTGCTCCTTGTGCGATGCTGCGCTGCCGAGTTTGGCTCAACTTCGCATTCACTTAACCACTCACCAGTATGATTTAAATGGCATTAGTCCGGAGTACAATTCCTCCTTCTTTCGCTCGTTTTACCCTGATGGATTGGACTGCACTGCCTCGGATCTTGCTGCTCGCATAGCTGAGGACTTCGAGATTCAGGAGTTTGATCGCTACTACAACGTCTGTACTGAAAGTGGACAAGAACTGGATCTTTTTGATTCCGAAACCGAGCAGAGCGATGAGGAAACCAAGACACACACTTGTCTGCTATGCGGAGAGGTTGCGAGTACACTGACGATTCTGATGGAGCACCAAAAGACCCTGCATGCTGACGGTGCGACCGATCTTCCCTGTCTCTGCGAAAATTGTGGAGCTCGATTCGTCAGCAAAGCTTTGCTGCAACAACACCGCAGACATCGGTGCGCCAAGAAATACTCCCGTTTTCACTGCCAGAGTTGCAATGTCCGATTCGTGTGGCAGTCCAACTATGAGCGCCACCTGAAGTCGCACCATAACAAAAATGAAGATGAAGAAATGGCCACCAAGTTGCAATGCGACGAATGCGATAAGGTATTCATCTGGCACAAAGATCTCAACCGTCACAAGCGACTCCATCAACCGCAGTCGGCAGCCCAGTTCGACTGTCCCCATTGCCACCGCAGGTTTCACCGCAAGGATGGTCTAAAGTCCCACCTAAAAGTACATGCGGGAGAACCAGCTCAAGTAAGGGAGCTGCGTACATTACCTAACGTTGTCCAAGGACTGATTTTGTCCCGGCTTAGTCGTCCTCATGGCTGCAAGTTGATTCAGTGCATGATCTGCCTCTCACGCCACTCGAAGATCAGTGATCTGAGGACTCACATGGGCTCCCATCAATACGGATTAAGTTTCACCGAAGCGAGAGATATTCCTAGTGTCTCGAAAGCTTTTTACCCCGAACTGGAAATTGCCTTAGAAAGAAACGAACTTGCCGAAAGGATTATGGCTGATGTGGAAAAGGGATTCGAGTTGGATCGATTTATTTCTATTACAAGTGAGGCTGGCCTAGAACTGAATCTCGACAGCAGTGAAACTGATACTGAGTCCGAGCAAGAGGAGAATAAATCAGCTCAAAGCTATGCCTGCAATCTCTGTGCAGCGGTTGTGAGGAGAAAGCATCAGTTGTATGCCCATCAGCTGGCAGAGCACAAGTGGGAGGACGCATCCCTTGTATGCTTCCATTGCCAGGCTAGGTTTGTAAACGAATCTTTGCTCGATCATCACTCCAGAACGCTCTGTCACAATGCGCAGAAGGTCTTTCAGTGTCGCAAGTGTCCGCTTCGCTTCCGCTGGCGGGAGAATCTTAAGATCCACTTGGAGCTGTTCCATCAGCAGGCCGAAATTGCAGCCCAAGAAGAATCCCCTCAAGCAGAAGGCGACCTGCAGTGCGGAAAGTGCCAGCGCAGCTTCAAGATGCAAAAGGATCTCACGCGTCATACACTTATGCACGGCCAGGAATCGAATATCTTCCGGTGCCGTTGGTGTGCGCGTCGCTTTTATCGCAGGGCCAATCTTCTGCAGCATATCGCACGGCATGGGATAAGTGTAAGCCAATTGCCTTATGCTGAGGCAATCCTGGACTCGTACGGGAATCCTGGAGGTCAAAAAAAGGTGGAGTGCCGGGTGTGCAGTGTGAGCTTTCCCACCATCGCGGCATTGCGCTTGCATTTGGAAACCATGCCCACAGGAAGTCACCACGACTTCTCCTCACTTCAAAACTACTCGATTACCAGCCAATTGGGCTTCGAGATGGATCTGGATGATTCGGAgactgatgatgatgacacTAGGACACATACAAAACCACCTGGCGCCCCTGATTCTTACACCTGTGGTATGTGCCAACTGAGGTGTTCGCGAAAGTACGAGCTACATCAACACCAGCAGGCCATGCACCGGATGGAGAAGATCCCCGACGGCTGTGACAGGTGCATCTTCAAGAGCGTCTGTGCTGAAATCATTGCCCATCATAAAAAGACGCAGTGTGAGAACCGGGAAAAGCAATTCACTTGCATTCACTGCGGCTTCAAGTTCATGTGGGAATCTAATCTGTTGCATCACATGCAGTTGCAGCATGAAAAGGTCGAGGATCAAGATCTCGATGAATCTAAGGAGGCGTCTGGTGATGAACCAAAAGCCGAGTGCCAGGTCTTCAAGTGCGGCCTTTGTACGAGGAAATACAACCGCAAGGATCGGCTCACGGCGCACTTGAAGAAGTTCCATGGTCCCGATGGCAAGGGCCCCAGTCAAGCGAAGGTCTCGAATAGACCCACATCTCCCAAGGAACCGAAGCGGTTCCTGTGTGCCTTTTGCGGCAAGGCGGTCAGTTCCTCGTCCAATCTGATCATCCATATGCGCCGCCATACCGGGGAGAAGCCTTTCAAGTGCGACTATTGCCCAATGGCCTTCCCCCGATCCTCTGACCTCCAGTGCCACCGCCGGACGCACACCGGCGAACGCCCACATGTGTGCACCGTCTGCCAGAAGGGATTCGCCCGCTCGTACAAACTGCAGCAGCACATGCGAATCCACAGCGGGGAGCGTCCCTACAAGTGCACCTATTGCGAGAAAAGCTTTACGCAGTCCAACGACCTGACTCTTCACATCCGCCGGCACACAGGCGAGCGGCCCTACCAGTGCGGAGTCTGCGGGGAGCGTTTTATCCAGGGCACCGCCCTCAAGAACCATCGTATGCAGCAGGGCCACTACGAGGAGGGACAGGAGTTGGGCGAGCCTACGAGGCGAACGGTTCTGGAGCAGTTTAGTATATAA
Protein Sequence: MLPSDICRTCGLQNSQLLPLSTCLDRDASKSYYDVLEELTKINTQLESSDDNLPQHLCTDCWTRLESAYAFVEQAKRVKGELLARLRECLDEMPIDIPQEEQNIKTEVDLDDEGNKCDEVESTGLATLELKWRPESDSDEDFLDAAESDEDEVDKKTYHLRRSSRKVKQAVESEDEEVKPPEPSPVKRRRGRPPGPAKSTSMTTDGRHACEVCGKTFSWYRDMQRHARIHFEQASFVCDTCGKGFLRKDKYMFHLRCHKKREAKWKALQVGKEWRFAERLYSSGRLKKIDCKLCGLSCQRMEELRTHIKSHVNVESLDNLRKDSDVVREHFPGFPCDLNIIKQQICAEIAEGHFEKFACIVNFHGYELGLSDSDEECDSKESKYNCNVCNLSFTRKYRLIKHTLEEHSQSDASTLPWQRCSSCKVGFLCLTLFNQHVSNHCHSKIKRYRCRKCPGKFMWPDNLQNHACSHRRDEDKTIPKQMMCSLCDAALPSLAQLRIHLTTHQYDLNGISPEYNSSFFRSFYPDGLDCTASDLAARIAEDFEIQEFDRYYNVCTESGQELDLFDSETEQSDEETKTHTCLLCGEVASTLTILMEHQKTLHADGATDLPCLCENCGARFVSKALLQQHRRHRCAKKYSRFHCQSCNVRFVWQSNYERHLKSHHNKNEDEEMATKLQCDECDKVFIWHKDLNRHKRLHQPQSAAQFDCPHCHRRFHRKDGLKSHLKVHAGEPAQVRELRTLPNVVQGLILSRLSRPHGCKLIQCMICLSRHSKISDLRTHMGSHQYGLSFTEARDIPSVSKAFYPELEIALERNELAERIMADVEKGFELDRFISITSEAGLELNLDSSETDTESEQEENKSAQSYACNLCAAVVRRKHQLYAHQLAEHKWEDASLVCFHCQARFVNESLLDHHSRTLCHNAQKVFQCRKCPLRFRWRENLKIHLELFHQQAEIAAQEESPQAEGDLQCGKCQRSFKMQKDLTRHTLMHGQESNIFRCRWCARRFYRRANLLQHIARHGISVSQLPYAEAILDSYGNPGGQKKVECRVCSVSFPTIAALRLHLETMPTGSHHDFSSLQNYSITSQLGFEMDLDDSETDDDDTRTHTKPPGAPDSYTCGMCQLRCSRKYELHQHQQAMHRMEKIPDGCDRCIFKSVCAEIIAHHKKTQCENREKQFTCIHCGFKFMWESNLLHHMQLQHEKVEDQDLDESKEASGDEPKAECQVFKCGLCTRKYNRKDRLTAHLKKFHGPDGKGPSQAKVSNRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCPMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRMQQGHYEEGQELGEPTRRTVLEQFSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548203;
90% Identity: iTF_00605711;
80% Identity: -