Dlon002206.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila longiperda
Gene Symbol
zfh1
Assembly
GCA_035042125.1
Location
JAWNLV010000010.1:8135218-8140969[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 4.6e-05 0.0031 17.9 1.0 1 23 147 169 147 169 0.97
2 15 0.00089 0.06 13.8 1.2 3 23 177 197 175 197 0.94
3 15 9.7e-05 0.0065 16.8 0.1 1 23 399 421 399 421 0.98
4 15 0.00034 0.023 15.1 0.9 1 23 427 449 427 449 0.98
5 15 0.0024 0.16 12.5 4.3 1 20 481 500 481 504 0.89
6 15 0.009 0.6 10.7 3.0 1 23 556 578 556 578 0.94
7 15 0.04 2.7 8.6 0.4 1 23 584 607 584 607 0.97
8 15 0.028 1.9 9.1 0.4 3 19 616 632 615 633 0.95
9 15 0.00017 0.011 16.1 5.7 1 23 642 664 642 664 0.97
10 15 0.05 3.4 8.3 0.4 2 23 670 691 669 691 0.96
11 15 9.9e-06 0.00067 20.0 1.0 1 23 700 722 700 722 0.98
12 15 0.0011 0.075 13.5 0.1 3 23 730 750 728 750 0.97
13 15 6e-05 0.004 17.5 0.5 1 23 756 778 756 779 0.95
14 15 0.051 3.4 8.3 0.4 1 23 789 811 789 811 0.97
15 15 0.0016 0.11 13.0 0.4 1 23 1321 1343 1321 1343 0.98

Sequence Information

Coding Sequence
ATGAACAATCCGGACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAACACCGTCGCCGACGACAGCGAAACAGAGATGACAGCAGCCTATTTGGTCAACGCTGCCGCCAACGATGACGATCTTGATCATATGGCAGCCGAGAATCTCATCTTTATGGCACGCGACGGCCAACTGAGCGAAATCATCGCCGCCAATGAGGCAAATGTCGGCATCAGCACAGTGCTAATCACGGAGAGCGACGGAAATAACGGTGTGGAATACGCCGAATCCTTTGACGACGATACCCAAGTCGTCACAGAGGAGATCATCACGGATGATTGGGTCCAGCATCAAGGCGCAGAGCGtgtGGAAATTGCGGCGGAACAAATCGCTGGCAATGGCAGCTCGCAGGAGCTGTTGGACATGCAACAGAATGAATATATGGCAATGCGTCCCTATCCCTGTGACTTTTGCAGTCGACGCTTTCGGAAGAGGGCCAGCCTCAACAATCACATGCTGGCGCATCAGAATGATCGTCCCCATCTCTGCAAGTTGTGCGGGGCGCGTTTCTCACGACGGGCGGAGCTCATCAGTCACTTCAAGGCGCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATTAAATTTGAGCCActacagcagctgcaacaccatcagcagcagcagcagcagcagcatcagcgacAAATTGAAGATAATTTCTATGAGCACGAATGGCCGCTGTAtcaggaacaggagcaggagcaggaaccAGAACAAGAGCATGAGCCGGAGCGGGAGCAGGTCGAAAAGCAGCTGGAGCAAAttaagaagcagcagcagctggagcggcaacagctggagcagcaacagctggagcagcaacagctggagcagcaacagctggagcagcatcagcagctgaTGCAACAATCGGTGGCACCACCCACCGCTGCCCGTGGACGTATCAGTCGCTTGAAGCTCAAAGAGGAACAATATATTGCCCCCGATAAACCGGAGACGGAGTTGCCTCAATACATGCATTGTGATGCGAATTGCGATCAATCACTTgccactaacaacaacaagaaccaaCTACAAGCAACGCCATCCAATgatgttgcaactgcagctgctgctgatggggCACAGGGGCAGGCAACGCTACGTTTTCCCGTGCTCGACGAGAGCAAACCCTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCTCTCGTCTCCCACATCAAGAATCATCGCGTGGATTCGCCGTTTGAGTGCAATCAGTGCCAGGAGATGTTCTGGGACAATTATAGTTTGCAGGAGCATCAGAAAACACATCAGTTCGAGGAGAGCAACTCGGAATATGATCCCGCATCGGCGGGCGAGGAGGATACGGCGAGTGAATCGGAAGCGGAACAGCTTTATGGTGATTTTTACTGCGGGGAATGCGGCATCTCCTTTCACCGGCAGGATTTGTTGCGGCGCCACTGCAAACAGCAGCACAGCAAGCAGCttactgcaacaacagctggtggcaacaacaacagtagtgtggcaactgcaactgcaacagcgaaGGATGCAGTGggtgtggcagctgcagctgcaactgatgccgatgctgatgctgatggtgatgatgcCAAAGATGCGGCACATTGTTGCCACACCTGTGGCAAATCATTTCCCAACGTACTCAAACTGCTCGCCCATGCCGAAATCCACAAACGTTTCCCGCCATTCAAATGTGTCCTGTGCGGAGGCAGCTTCTACGAGGAGCAGGCTATCAAGCGGCACCTGAGCACGCGGCATCCGCACGAGCTGAAGCAGAActcgtgtgtgttgtgtggcaAGGAGTGCCGGGATCGGAAGGCGCTGATTAAGCATGCGTGGGATCATTCGCGGGAGAAGTGCCACTCGTGCTCCAAGTGTGGTAAGAATTTCCACAACAAGGGGCGCCTGAAGCGGCACATGGCATCGCATCGCGACAAGTCCGTCGTGTGTGAAGTGTGCCAGGAGGAGTTCCCCGACGGACGCACTTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAATTGTTTCCCTGCCACGAGTGTGGCAAGACCTTTGGGTCGCGCAGCTCACAGCAGATTCACGTGCGCATCCACACGGGCGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGATGGCGGCACTCTCCGCAAACACGAGCGCATCCACACCGGCGAGAAGCCCTACGCCTGCTCCGTCTGTCCGCGTGCCTTCAATCAGCGTGTCGTCCTGCGGGAACACATCCGATCGCATCATTCGGGTCTGGATGCGGCACTTGGCACGTATCATTGCACGGTCTGCTCGGCGGATTTGAGCTCATCAAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACAAACACAGCCAAACAGCGACAGCCAATTACTGGTCCACGTAAATACAAACGTCGCCGGAAACTGCAGCCGCATGAAATTGCGCATATGCGCGCCGAGCACAAGGAGGAGGACGATTATGTGAGCGACTTGGACTACTGCGATCTGGATGTGGAGAATGTGGATGAGTTGCTGCAGAAGACAACCGCAGAGTCACCACCACCCACCAAAAAAGCGAAACGCAAACGCAAAGCGCCAATTAAATCAGGCGATGAGCAAAGATTGTGGGATGAGAAATTCCTGCAGCAGACGAGCAATGGAAACAGCGATGAGGCCTACAAAAGTTTCTTTCAAATAGACTCGCTAATGGTGGTCAATGATCAAACGTTGCAGCcggttgatgctgctgctgccaccaccAAGTTGCAGAAGTCTGAGATTAAGGAGGAAAAACTTAAAGGaggcagtcgcagcagcaaaagaaggGCTGCCAAAGCTGGCGGAGGAGCAGGATCAGCAGgcggaggagcagcaggagcaggtggaggaggagctgctgctgctccacgtCCACGCATGATACACACGGCCAAGTCGCAGAAGACAACTTCAAAGAAATCCCGCACAAGGAGCTATATCACACGCACCAGCACCaatgatcagcagcagcagggaggaggaggaggaggaggaacaaGTGGAGGAAGCCTCATCAAATCGCGCATTGTGGATGACTACGAGATCATCTCACCGGCCACACAGCCACCCAATCAAATCAGTTCCAGTCCACTGCACATCAAACAGGAGCAggaacatcatcatcatcagcagcagcatcatcatcatcagcagcagcagcagcagcaacgagtCCAGCTGCTCTTTGATGACAGCCATCTGCTCATCGATGCGGGCCTGTTGCGTGAGAAGACATACGAGAAATATAACCCCAGCATTGTTCAAGATCTCGAGGAGATTTTGCGTAGTCCCCCCAAGCATGAGCGGGATGATCGACGGCTGCGCTTTACCAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGTGAGGAGGAGGAACAGCATCTCATCAAGATCGAGCCCACGTCGCCGGATCTCCGCGAAATGGTCGAgagccagcagccagccacACTGCCAGCGTCCTCCTCCGCCTGCTCAACGGCGGCACGCACTTCCCGCCACCTGCGTCAGCTGACTGCAAAAGGTTCCGGTTGCGGTTCCATTTCGACTGCCACTTCCAGTTCCAGTGCCACTATTAGCACGCGATCCGCTTCCAAGCGCAATGCCAGCAAACAGCTTTCCAAGAAATCCActtccaacagcaacaagggcAACTCATCATCTTCTTATCTCGGCTACGGCGTCGACTCTTACAATTCGGGCGTGGCGGCCAATGCCAATAGCTCCTCGGATGTCAGTTCCGGTTTCTTTTCCATCTCCGAGGTCGTCTCGGCGGCAGATGCAGCGGATGCAGCTGCAaaggcggcggcagcagccagcaaaacGGAGCGAAAAATGCGTTGTTTTGAGTGCGAAATGTGCTCGTCCAATTTTCCAGATCGTGCCCAGCTGCTGgaacacatgcatatacacatcTAG
Protein Sequence
MNNPDYGGIQWIQQESNTVADDSETEMTAAYLVNAAANDDDLDHMAAENLIFMARDGQLSEIIAANEANVGISTVLITESDGNNGVEYAESFDDDTQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKRASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADEEAAAAAIKFEPLQQLQHHQQQQQQQHQRQIEDNFYEHEWPLYQEQEQEQEPEQEHEPEREQVEKQLEQIKKQQQLERQQLEQQQLEQQQLEQQQLEQHQQLMQQSVAPPTAARGRISRLKLKEEQYIAPDKPETELPQYMHCDANCDQSLATNNNKNQLQATPSNDVATAAAADGAQGQATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEDTASESEAEQLYGDFYCGECGISFHRQDLLRRHCKQQHSKQLTATTAGGNNNSSVATATATAKDAVGVAAAAATDADADADGDDAKDAAHCCHTCGKSFPNVLKLLAHAEIHKRFPPFKCVLCGGSFYEEQAIKRHLSTRHPHELKQNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKGRLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAALGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKEEDDYVSDLDYCDLDVENVDELLQKTTAESPPPTKKAKRKRKAPIKSGDEQRLWDEKFLQQTSNGNSDEAYKSFFQIDSLMVVNDQTLQPVDAAAATTKLQKSEIKEEKLKGGSRSSKRRAAKAGGGAGSAGGGAAGAGGGGAAAAPRPRMIHTAKSQKTTSKKSRTRSYITRTSTNDQQQQGGGGGGGTSGGSLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHHHHQQQHHHHQQQQQQQRVQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERDDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPATLPASSSACSTAARTSRHLRQLTAKGSGCGSISTATSSSSATISTRSASKRNASKQLSKKSTSNSNKGNSSSSYLGYGVDSYNSGVAANANSSSDVSSGFFSISEVVSAADAADAAAKAAAAASKTERKMRCFECEMCSSNFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00542584;
90% Identity
iTF_00499020;
80% Identity
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