Basic Information

Insect: Drosophila littoralis
Gene Symbol: -
Assembly: GCA_018903485.1
Location: JAEIGF010000383.1:3315207-3319669[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.3 19 5.8 3.3 2 23 369 391 368 391 0.96

2 18 0.007 0.44 10.9 1.6 2 23 434 455 433 455 0.94

3 18 5.3 3.3e+02 1.8 3.0 2 17 466 481 465 492 0.75

4 18 6.2 3.9e+02 1.6 0.8 2 23 495 517 495 517 0.91

5 18 0.025 1.6 9.2 0.3 3 23 525 545 523 545 0.95

6 18 9.4e-05 0.0059 16.8 0.3 1 23 553 576 553 576 0.98

7 18 0.00044 0.027 14.7 0.3 2 23 581 602 580 602 0.97

8 18 3.5 2.2e+02 2.4 0.0 1 19 610 628 610 630 0.89

9 18 0.00034 0.021 15.1 0.8 1 22 650 671 650 674 0.90

10 18 0.052 3.2 8.2 1.0 1 21 679 699 679 700 0.92

11 18 0.0043 0.27 11.6 0.5 1 23 719 744 719 744 0.97

12 18 0.036 2.2 8.7 1.6 2 23 760 782 759 782 0.93

13 18 0.023 1.4 9.3 0.1 3 22 789 808 787 810 0.88

14 18 0.0092 0.58 10.5 0.3 2 23 814 836 813 836 0.96

15 18 6.2e-05 0.0039 17.4 1.7 1 23 842 864 842 864 0.96

16 18 0.025 1.6 9.1 1.7 1 23 868 891 868 891 0.93

17 18 2.8e-06 0.00017 21.6 0.7 1 23 897 920 897 920 0.97

18 18 0.016 1 9.8 0.8 1 23 924 952 924 952 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.3	19	5.8	3.3	2	23	369	391	368	391	0.96
2	18	0.007	0.44	10.9	1.6	2	23	434	455	433	455	0.94
3	18	5.3	3.3e+02	1.8	3.0	2	17	466	481	465	492	0.75
4	18	6.2	3.9e+02	1.6	0.8	2	23	495	517	495	517	0.91
5	18	0.025	1.6	9.2	0.3	3	23	525	545	523	545	0.95
6	18	9.4e-05	0.0059	16.8	0.3	1	23	553	576	553	576	0.98
7	18	0.00044	0.027	14.7	0.3	2	23	581	602	580	602	0.97
8	18	3.5	2.2e+02	2.4	0.0	1	19	610	628	610	630	0.89
9	18	0.00034	0.021	15.1	0.8	1	22	650	671	650	674	0.90
10	18	0.052	3.2	8.2	1.0	1	21	679	699	679	700	0.92
11	18	0.0043	0.27	11.6	0.5	1	23	719	744	719	744	0.97
12	18	0.036	2.2	8.7	1.6	2	23	760	782	759	782	0.93
13	18	0.023	1.4	9.3	0.1	3	22	789	808	787	810	0.88
14	18	0.0092	0.58	10.5	0.3	2	23	814	836	813	836	0.96
15	18	6.2e-05	0.0039	17.4	1.7	1	23	842	864	842	864	0.96
16	18	0.025	1.6	9.1	1.7	1	23	868	891	868	891	0.93
17	18	2.8e-06	0.00017	21.6	0.7	1	23	897	920	897	920	0.97
18	18	0.016	1	9.8	0.8	1	23	924	952	924	952	0.88

Sequence Information

Coding Sequence: ATGTCGGAGAATTCGAATATAAACATCGAAAATGGGCCAAGCTGCCTGCATTGCAGTGCGTACAATTCAAAGCAACAATATCAGGAAATATTCGATGAAGTGGGCATCGAAATTGAACTAGCCGACTTGCTGGCCAAATATTTCCAAATAGTTGTCAAGCCAGACGCCCAAAAGTCGCAGCTGCTGTGCCAGGAGTGCGTAAATACGCTGATACGCTTCTTTGACATAGACGAATTGCAACGGGAGCAGGATGCCGCCAATGCAGGCAAAAAGAATGCCGACAAGCAGCAGGAGCTTGTAATTGTCTCGCCGCCCGTGCCCGCAGTTGCCGCCAAAAAGATTGCAAAGCCCGCCAAGAAGCAGAGCCCGCCGCCGCCGCCGCCCAAAGCAGCGCCTACAGCGGCAAAAAGTACGCCAGTTGTAGTCAAACGGTTGGCGACATCTGTTAAATCAGAGAAACCTTCGTCGGCGGCTACTACCGATGCTACGGATGCTCCTCCACCAATTGCCTCTGCAGTAGCCCCGGCCATACGCATTACCAGAGCCAGAACTGTTACCCCGAAACGTTTGCCGGTTAAAACTAAGGAAGCCGTCAAAGCGGTCGCTAAAAGTCACAGCAGCAGAGAAGCCGGGCCAGCGGAACAGGAGCAGATAAGCGCACTAATACGTGACATTCTTGACGATGAGGAGACGCCAGCAGACAATAAATTTGCCGAGGCAGCAGCCACAGTGCGACAGCTGGAGAAGCAATCAGGCACGAATAAGCGCCAGCTGAAGGTAGTGGTGCAGCAAGAGCAGCAAGAGCAGGCGGAGGAAGAGTGCCAGGCTCTGAACGAGCAGGAAAACAATGAAGAGCTGGAGTTTCTGCTCGAGCCTGATGATAGCTCCTCCGACTTGGATGTGCGTCATTTCAAAGTGGAGCGTAAAGTCAAAAGCGTCGCATCACAGTCACAGAACGAGAGCCAAAGCGATGATGAATCCTTCAAAGTGGAGCCTTTCAACTTTGTTTTGATCAAGGAATCTGATAACATTGGCGATCTGCATGAGTATTTGTCCACCGTGGTCAAGACCAGTTTTGAGACTTTGCAGTTCGATTGGGCCACGGTGTGCCGTCATTGCTCGCTAAAGTCCACCAAATATGAGACGTTGCTCAATCATATGCTGAAGCGACATCAGCTGTCGGAGGATCGCTACAGCTGTCCCATTGAGGGCTGTAAGGCGGAGCTGCAGGGCCGCAAATACCTGGCCATGCATTTGGTGGTGCTGCATGCGCCCGTGGCGGAAATATCCATTTATGGCAAGTGCCCCGAGTGCAACATGACCTTCTCGAACATATTGCAATACAACAAACACTCCTGCGCGCATGTCATCAAGAAGCGTCGCGGCATACGTCTGTACTGTGAGATGTGCGGCTTGGAGTTTCCCTCCTGGAAGCGCTTTAATTTCCACAATCAATTTCATTTGGAGCGCCACAGACCGCGCGTCTGTTTTGTGTGCGACTATGCGGACACCAATATAGATGAGCTATTCCATCATTTGCACTATGCACACGAGCCCGAGGGCACGCTCTTCTGTGATCTTTGTGATCGCAATTTTCGTGACGCTGCCGTCTTTATGGAACACAATAAGTCGCATTCGAATGTCAGCAGCACCACCTACAGCTGCTCCGAGTGTAGCGCCAATTTCGAGACACGCGGTCGACTCAATGCTCACATGCGCTCCGTACATGGCAGCGTGGTCAGCTGCGAGCTGTGCAGCCGCGAATTTGCCACGGAGGCCACCTACAACCTGCACATGAAGACCCATCTAATCATTGAGCGCGAGGTGCATGTGTGCAGCAATTGCGGGCTGCTTAGCGAGAATAACGACAAAATGATGGCCCATGTGGGAAATGAGGAGTCAGCCTGCCTTGGCATGGATGTCTATGCGGAACTGTTGCGCAATGCTTATATATGTGAATATTGCTCCGCGTACTTTAAGCATAGTAGTGATTTGCGCGCCCATCGTGATTCGGGCGTGCATAAGGATGGTTTCTTCTTTTGTCAGCCTTGTGGCAAGGAGTTTGCTGACATGAAACTCTATCGTCATCATTTGCGCAACTTTCAGCAACAGCGCACGGATGTGGCGCATCGCAGGCTGGAGATTGGCCTGTACTACATGTGTGATTATGAGGATTGCACTGAGGCCTACATAAACTGGAATTCGCTGTACACACATAAGCGACGCACACACGACGCCATCTGCAAGCGGGTGCCTCAGCCCAAATATAACGAATGGATCTGCCAGTTCTGTCAGAAGGAGTGTCGCTCCAAAATGTCGCTCTCGGTGCATGTGGCGCGTAGTCACAACAACAACAATGTAATTTGCCCGCTGTGCAAGGCCTCGTACAAGGATAAGGAAGCATTGGACAAACATAACGCCTATTGGCATGAGCCCATCGAATGTCAGCTGTGCCTCAAGGTGGTCAAAAATCGTCGCAACTATGACACACACATGAATGTGGTGCACTCGAACAACAAACGCTACTTGTGCAGTGTCTGCCAAAAGGGTTTCTATCATAAAAGTGAAATGGAGGCGCATCAGCGGCTGCATACCCAGTCGTTCAGCTGCGAGCACTGTAGCTTCATCACGCGGAACAAGAAGTCGCTGTCGGTTCATGTGCTGGGACAGCACTTTAAACGCTTCGCCTTCGAGTGCAAGATCTGCGATAAGCGCTTCGGACGTAGCCAGGGTCTATCGAATCATATGCAGCGTGTGCATGGCTCCAGGTATACCTGTCGTGATTTCTTTGACGAGGGCTGCAGCAAGTCCTTTGGCTCCACGACGAAGCTCAATATGCATGTGCGTAAGGTGCACAACAGCAGCATTTACCTGGAAGATGAGCCAGTCAAGGCGGAGGAGGAGGGTGAGGATGGCGAGGAACTGGAAGAGGAGGAGGGATCCACCAGCGATGGTCCATCCACATCAAAGAAACGCTGCATACGCATCAATGCAAGCACACAAATCGAGTTTATAGGCGATGCAGCTGTTGCCGAGGAAAACGAGAGCCTCGCAGGCTCGGAAATCTTTGAGGAGTTTCAGGAAGAGATCAAGGAAGCGGACGCGGAGCCGCCAAAATTAAAAAAGCAAAGGCAATGTTGA
Protein Sequence: MSENSNINIENGPSCLHCSAYNSKQQYQEIFDEVGIEIELADLLAKYFQIVVKPDAQKSQLLCQECVNTLIRFFDIDELQREQDAANAGKKNADKQQELVIVSPPVPAVAAKKIAKPAKKQSPPPPPPKAAPTAAKSTPVVVKRLATSVKSEKPSSAATTDATDAPPPIASAVAPAIRITRARTVTPKRLPVKTKEAVKAVAKSHSSREAGPAEQEQISALIRDILDDEETPADNKFAEAAATVRQLEKQSGTNKRQLKVVVQQEQQEQAEEECQALNEQENNEELEFLLEPDDSSSDLDVRHFKVERKVKSVASQSQNESQSDDESFKVEPFNFVLIKESDNIGDLHEYLSTVVKTSFETLQFDWATVCRHCSLKSTKYETLLNHMLKRHQLSEDRYSCPIEGCKAELQGRKYLAMHLVVLHAPVAEISIYGKCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRVCFVCDYADTNIDELFHHLHYAHEPEGTLFCDLCDRNFRDAAVFMEHNKSHSNVSSTTYSCSECSANFETRGRLNAHMRSVHGSVVSCELCSREFATEATYNLHMKTHLIIEREVHVCSNCGLLSENNDKMMAHVGNEESACLGMDVYAELLRNAYICEYCSAYFKHSSDLRAHRDSGVHKDGFFFCQPCGKEFADMKLYRHHLRNFQQQRTDVAHRRLEIGLYYMCDYEDCTEAYINWNSLYTHKRRTHDAICKRVPQPKYNEWICQFCQKECRSKMSLSVHVARSHNNNNVICPLCKASYKDKEALDKHNAYWHEPIECQLCLKVVKNRRNYDTHMNVVHSNNKRYLCSVCQKGFYHKSEMEAHQRLHTQSFSCEHCSFITRNKKSLSVHVLGQHFKRFAFECKICDKRFGRSQGLSNHMQRVHGSRYTCRDFFDEGCSKSFGSTTKLNMHVRKVHNSSIYLEDEPVKAEEEGEDGEELEEEEGSTSDGPSTSKKRCIRINASTQIEFIGDAAVAEENESLAGSEIFEEFQEEIKEADAEPPKLKKQRQC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00551033;
90% Identity: iTF_00490945; iTF_00506273; iTF_00617059; iTF_00563341; iTF_00526735; iTF_00475380;
80% Identity: -