Basic Information

Gene Symbol
-
Assembly
GCA_037075305.1
Location
JBAMCE010000550.1:2225019-2229824[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.34 23 5.8 3.3 2 23 366 388 365 388 0.96
2 19 4.6 3e+02 2.2 0.0 1 23 395 420 395 420 0.93
3 19 0.008 0.53 10.9 1.6 2 23 431 452 430 452 0.94
4 19 6.1 4e+02 1.8 3.0 2 17 463 478 462 489 0.75
5 19 7.1 4.7e+02 1.6 0.8 2 23 492 514 492 514 0.91
6 19 0.028 1.9 9.2 0.3 3 23 522 542 520 542 0.95
7 19 0.00011 0.0071 16.8 0.3 1 23 550 573 550 573 0.98
8 19 0.00046 0.031 14.8 0.3 2 23 578 599 577 599 0.97
9 19 3.9 2.6e+02 2.4 0.0 1 19 607 625 607 627 0.89
10 19 0.0003 0.02 15.4 1.0 1 22 647 668 647 671 0.90
11 19 0.059 3.9 8.2 1.0 1 21 676 696 676 697 0.92
12 19 0.0049 0.32 11.6 0.5 1 23 716 741 716 741 0.97
13 19 0.041 2.7 8.7 1.6 2 23 757 779 756 779 0.93
14 19 0.0086 0.57 10.8 0.1 3 22 786 805 784 807 0.88
15 19 0.011 0.7 10.5 0.3 2 23 811 833 810 833 0.96
16 19 7.1e-05 0.0047 17.4 1.7 1 23 839 861 839 861 0.96
17 19 0.029 1.9 9.2 1.7 1 23 865 888 865 888 0.93
18 19 4e-06 0.00026 21.3 0.9 1 23 894 917 894 917 0.97
19 19 0.018 1.2 9.8 0.8 1 23 921 949 921 949 0.88

Sequence Information

Coding Sequence
atgtCGGAGAATTCGAATATTAACAACGAAAATGGACCTAGCTGCCTGCATTGCAGTGCGTACAATTCAAAGCAACAATATCAAGAAATTTTCGATGAGGTGGGCATAGAAATTGAACTCGCCGACCTGCTGGCCAAATATTTCCAATTAGTTGTCAAGCCAGACCCACAAAAGTCGCAGCTGCTGTGCCAGGAGTGCGTAAATACGCTGATACGCTTCTTTGACATAGACGAGTTGCAACGGGAGCAAGATGCCGCCAATGCAGGCAAAAAGCAGCAGGAGCTTGTAATTGCTTCACCTCCCGTGCCTGCAGTTGCCGCCAAAAAGGATGCAAAGCCCGCCAAAAAGCAGAgcacgccgccgccgccgcccaaaGCAGCGCCAACAGCGGCAAAAAGTACGCCAGTGGCAGTCAAACGTTTGGCGACATCTGTTAAATCAGAGCAATCTCCGTCGGCTGATGCTACGGATGCTCCTCCACCAAAAGCCCCTGCAGGAGCCCCGACCGTACGCATTACCAGAGCGAGAACTGTTACCCCGAAACGTTTGCCGGTTAAAATTAAGGAAGCGGTCAAAGCAGGCGCAAAACCGGGCGCTAAAAGTCACAGCAGCAGAGAAGCCGGGCCAGCGGATCAGGAGCAGATAAGCGCACTAATACGTGACATTCTCGACGATGAGGAGGCGCCGGCAGATAATAAATTCGCTGAGGCAGCAGCCACAGTGCGACAGCTGGAGAAGCAATCGGGCACGAATAAGCGCCAGCTGAAGGTGGTGCTGCAGCAAGAGCAGGAGGAGCACGCAGAGAAACAGTGCCAGGCTCTGAACGAACAGGAAAACAATGAGGAGCTAGAGTTTCTGCTCGAGCCTGACGATGGCTCCTCCGACTTGGATGTGCGTCATTTCAAAGTGGAGCGTAAAATCAAAAGCGTCACATCGCAGTCACAGAATGAGAGCCAAAGCGATGATGAATCCTTCAAAGTGGAGcctttcaattttgttttgatcAAGGAATCTGATAACATTGGCGATTTGCACGAGTATTTGTCGACCGTGGTCAAGACCAGCTTTGAGAAATTGCAATTCGATTGGGCCACGGTCTGCCGTCATTGCTCGCTAAAGTCCACCAAATATGAGACGTTGCTCAATCACATGCTGAAGCGTCATCAGCTGCCGGAGGATCGCTACAGTTGTCCCATTGAGGGCTGTACGGCGGAGCTGCGGGGCCGCAAATACCTGGCCATGCATTTGGTGGTGCTGCATGCGCCCGTGGCGGAAATACCCATTTATGGCAAGTGCCCCGAGTGCAACATGACCTTCTCGAACATATTGCAATACAACAAACACTCCTGCGCGCATGTCATCAAGAAGCGTCGTGGCATACGTCTGTACTGCGAGATGTGCGGCTTGGAGTTTCCCTCCTGGAAGCGCTTTAATTTCCACAATCAATTTCATTTGGAACGCCACAGACCGCGCGTCTGTTTCGTGTGCGACTATGCGGACACCAACATAGATGAgctattccatcatttgcactACGCACACGAGCCCGAGGGCACGCTCTTCTGTGATCTTTGTGATCGCAATTTTCGTGACGCTGCCGTCTTTATGGAGCACAATAAGTCGCATGCGAATGTCAGCAGCACCACCTACAGCTGCTCCGAGTGCAGCGCCAATTTCGAGACACGCGGCCGACTCAATGCTCACATGCGCTCCGTACATGGCAGCGTGATCAGCTGCGAGCTTTGCAGCCGCGAATTTGCCACAGAGGCCACCTACAATCTGCACATGAAGACGCATCTAATCATTGAGCGCGAGGTACATGTGTGCAGCAATTGCGGTCTGCTTAGCGAGAATAACGACAAAATGATGGCTCATGTGGGAAATGAGGATTCAGCCTGCCTTGGCATGGATGTCTATGCGGAACTGTTGCGCAATGCTTATATATGCGAATATTGCTCCGCGTACTTTAAGCACAAAAGTGACTTGCGCGCCCATCGCGATTCGGGCGTGCATAAGGATGGTTTCTTCTTTTGTCAGCCGTGTGGCAAGGAGTTTGCCGACATGAAACTCTATCGTCATCATTTGCGCAACTTTCAGCAACAGCGCACGGATGTGGCGCATCGCAGGCTGGAGATTGGTCTGTACTACATGTGTGATTATGAGGATTGCACCGAGGCCTACATAAACTGGAATTCGCTGTACACACATAAGCGACGCACACACGACGCCATCTGCAAACAAGAGCCTCAGGCCAAATATAACGAATGGATTTGTCAGTTCTGCCAGAAGGAGTGCCGCTCCAAAATGTCGCTCTCGGTGCACGTGGCGCGCAGTCACAACAACAACAATGTGATTTGCCCGCTGTGCAAGGCCTCGTACAAGGATAAGGAGGCATTGGCCAAGCATAACGCCTATTGGCATGAGCCCATCGAATGTCAGCTGTGCCTAAAGGTGGTCAAAAATCGTCGCAACTAtgacacacacatgaatgtgGTGCACTCGAACAACAAACGCTACTTGTGCAGTGTCTGCCAAAAGGGTTTCTATCACAAAAGTGAAATGGAGGCGCATCAGCGGCTGCATACACAATCGTTCAGCTGCGAGCACTGTAGCTTCATCACGCGGAACAAGAAGTCGCTGTCGGTTCATGTGCTGGGACAGCACTTCAAACGCTTCGCCTTCGAGTGCAAGATCTGTGATAAGCGCTTCGGACGTCGCCAGGGTCTATCGAATCATATGCAGCGTGTGCACGGCTCCAGGTATACCTGTCGTGATTTCTTTGACGAGGGCTGCAGCAAGTCCTTCGGCTCCACGACGAAACTCAATATGCATGTGCGTAAGgtgcacaacagcagcatttaCCTGGAAGATGAGCCAGCCAAGGCGGAAGAGGAGGGTGAGGAGGGCGAGGAACTGGAAGAGGAGGAGGGATCAACCAGCGATGGTCCATCCACATCAAAGAAACGCTGCATACGCATCAATGCAAGCACGCAAATCGAGTTTATAGGCGACACAGCTGTTGCCGAGGATAACGAGAGCCTCGCTGGCTCGGAAATCTTTGAGGAGTTTCAGGAGGAGATCAAGGAAGCGGACGCGGTCGCGGTGccgccaaaaccaaaaaagcaaaggcaatGCTAA
Protein Sequence
MSENSNINNENGPSCLHCSAYNSKQQYQEIFDEVGIEIELADLLAKYFQLVVKPDPQKSQLLCQECVNTLIRFFDIDELQREQDAANAGKKQQELVIASPPVPAVAAKKDAKPAKKQSTPPPPPKAAPTAAKSTPVAVKRLATSVKSEQSPSADATDAPPPKAPAGAPTVRITRARTVTPKRLPVKIKEAVKAGAKPGAKSHSSREAGPADQEQISALIRDILDDEEAPADNKFAEAAATVRQLEKQSGTNKRQLKVVLQQEQEEHAEKQCQALNEQENNEELEFLLEPDDGSSDLDVRHFKVERKIKSVTSQSQNESQSDDESFKVEPFNFVLIKESDNIGDLHEYLSTVVKTSFEKLQFDWATVCRHCSLKSTKYETLLNHMLKRHQLPEDRYSCPIEGCTAELRGRKYLAMHLVVLHAPVAEIPIYGKCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRVCFVCDYADTNIDELFHHLHYAHEPEGTLFCDLCDRNFRDAAVFMEHNKSHANVSSTTYSCSECSANFETRGRLNAHMRSVHGSVISCELCSREFATEATYNLHMKTHLIIEREVHVCSNCGLLSENNDKMMAHVGNEDSACLGMDVYAELLRNAYICEYCSAYFKHKSDLRAHRDSGVHKDGFFFCQPCGKEFADMKLYRHHLRNFQQQRTDVAHRRLEIGLYYMCDYEDCTEAYINWNSLYTHKRRTHDAICKQEPQAKYNEWICQFCQKECRSKMSLSVHVARSHNNNNVICPLCKASYKDKEALAKHNAYWHEPIECQLCLKVVKNRRNYDTHMNVVHSNNKRYLCSVCQKGFYHKSEMEAHQRLHTQSFSCEHCSFITRNKKSLSVHVLGQHFKRFAFECKICDKRFGRRQGLSNHMQRVHGSRYTCRDFFDEGCSKSFGSTTKLNMHVRKVHNSSIYLEDEPAKAEEEGEEGEELEEEEGSTSDGPSTSKKRCIRINASTQIEFIGDTAVAEDNESLAGSEIFEEFQEEIKEADAVAVPPKPKKQRQC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00551033;
90% Identity
iTF_00534744;
80% Identity
-