Basic Information

Insect: Drosophila limbata
Gene Symbol: -
Assembly: GCA_963924055.1
Location: OZ001355.1:18533257-18536952[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.062 6.2 8.1 3.6 2 23 400 421 400 421 0.93

2 15 6.1 6.2e+02 1.8 3.0 2 17 432 447 431 458 0.75

3 15 0.01 1 10.6 0.4 3 23 491 511 489 511 0.96

4 15 0.00039 0.039 15.0 0.2 1 23 519 542 519 542 0.96

5 15 0.066 6.7 8.0 1.5 2 23 547 568 546 568 0.96

6 15 0.00041 0.042 14.9 0.4 1 22 616 637 616 640 0.90

7 15 2.1 2.1e+02 3.3 0.7 3 21 647 665 647 666 0.88

8 15 0.039 3.9 8.7 1.2 1 23 685 710 685 710 0.95

9 15 0.013 1.3 10.3 1.4 2 23 726 748 725 748 0.93

10 15 0.0028 0.28 12.3 0.1 3 23 755 776 753 776 0.92

11 15 0.0044 0.44 11.7 0.6 2 23 780 802 779 802 0.96

12 15 0.00036 0.036 15.1 1.7 3 23 810 830 808 830 0.97

13 15 0.25 26 6.2 0.4 3 23 836 857 834 857 0.92

14 15 7.1e-06 0.00072 20.5 2.2 1 23 863 886 863 886 0.97

15 15 0.0034 0.34 12.1 0.2 5 23 899 918 891 918 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.062	6.2	8.1	3.6	2	23	400	421	400	421	0.93
2	15	6.1	6.2e+02	1.8	3.0	2	17	432	447	431	458	0.75
3	15	0.01	1	10.6	0.4	3	23	491	511	489	511	0.96
4	15	0.00039	0.039	15.0	0.2	1	23	519	542	519	542	0.96
5	15	0.066	6.7	8.0	1.5	2	23	547	568	546	568	0.96
6	15	0.00041	0.042	14.9	0.4	1	22	616	637	616	640	0.90
7	15	2.1	2.1e+02	3.3	0.7	3	21	647	665	647	666	0.88
8	15	0.039	3.9	8.7	1.2	1	23	685	710	685	710	0.95
9	15	0.013	1.3	10.3	1.4	2	23	726	748	725	748	0.93
10	15	0.0028	0.28	12.3	0.1	3	23	755	776	753	776	0.92
11	15	0.0044	0.44	11.7	0.6	2	23	780	802	779	802	0.96
12	15	0.00036	0.036	15.1	1.7	3	23	810	830	808	830	0.97
13	15	0.25	26	6.2	0.4	3	23	836	857	834	857	0.92
14	15	7.1e-06	0.00072	20.5	2.2	1	23	863	886	863	886	0.97
15	15	0.0034	0.34	12.1	0.2	5	23	899	918	891	918	0.90

Sequence Information

Coding Sequence: atgtcggagaatttgaaaacaaataacaaagcTGAACCTAGCTGCCTGCATTGCAGAGTGCACAATTCAAAGCAGCCATTTCAGGAGATATTCGATGAAGTGGGAATTGAAATCGAACTGCCCGATCTGCTGGCCAAATATTTTCAGATAAATGTCAAACCCGATCCAAAAAAGCAGCAACTGCTGTGTGAAGAGTGCGTCAAAACATTAATTCGTTTCTTCGACATCGATGAACTGCAGCGGGAACAGGATGCGGCCAaggataaaaacaaaaagcaaaccaAGATTGAGAAAACTCCATCAGCTGCTGTTAAAAGGGAAACGAGGCCCAGTAAAAAACAAACGCCGCCAACGAATAAAACTAAAAGTGAACCCAAGAAGTTGACAACTTCTGTAAAGTTGGCAACATTAGAGGCTACTCCTCCGGCAAAAGCTGCTCCTCCATCAAAGGCTTCTCCTCCCGCTGAACCAGTTTCCATGCGCATCACCAGAGGAAAATCAGCAACTGCGTCACAAAAACGAACCCAGATCAATGCCAAGTCCAAACCAAGTGAAAAGTCCAAGGAAGCAGGAACGGGAGAGCAGGAGCAGATAAGCGAGCTCTTGCGTGACATACTGGATGAGGAGAAGACGCCTCCGGATGACAAATCCAAGGAGGGAGCGACGACAAGAGTGCGTAAAAAGGAGACGAAAGTCGCTGTCGTGGAGAAACAGGCTGAGCAGGAGGAGGGAGAGACGGACAAGCAGCAGGAAAATGTTGATGAGCTCGAGTTTCTGCTCGAATCTGGAGATGGCACCTCTGACTTGGAGATCCGTCAGTTCAAGGTGGAGAAGCAGACATCAATTGACACCGCACAGTCGCAAAGCGAGGATGAATCCCTCAAAGTGGAGCCCTTCAACTTTGTATTAATCAAGGAATCTGATGACATTGAAGATCTGTATGCATATTTGGCAACTGTGGTGAAGACTTGCTTCGAAACTCTGACCTTTGACTGGTCCACCGTGTGTTGTCACTGTTCGCTGAAGTGCAGCAAATTTGAGACCTTGTTGGCGCACATGCAAAAGTGCCACCAGCTGCCAGAGGAGCACTACAAGTGCCCCATTGAGGAGTGCAACTCCGAGTTGCACAGCTACAAATTCTTGGCCATGCATTTAGTTCTCTTGCATGCTCCTGTGGCAGACATACCAATTTATGGCAGCTGCCCGGAGTGCCACATGACCTTCTCTAACATATTGCAGTACAACAAACACTCCTGCGCCCATGTCATCAAGAAACGTCGTGGCATACGCTTGTATTGCGAAATGTGCGGCTTGGAGTTTCCCTCCTGGAAGCGCTTTAACTTTCACAATCAATTCCATTTGGAGAGGCACCGACCACGCGCCTGTTTTGTGTGCAATTATGCGGACACCAACATCGACGAACTGTTTCAGCATTTGCATTATTCACACGAGCCCGAAGGCACGCTCTTTTGTGATCTcTGTGATCGCTATTTTCGTGATCCTGCCGTGTTTACGGATCACAATAAAACCCACTCGAATGTCAACAGCATCACATTCGTCTGCACCATTTGTAGCGCCAGCTTTGAGACACGGGGACGTCTTAGTAACCACATACGCGCCACGCATGGATCCATCATTAGCTGTGAGCTGTGCTGTCGAGAGTTTGCCACGGAGGCTTCGTACAACATGCACATGAAGAAGCATCTGATCATTGAGCGTGAGGTGCATGTGTGCAGCAATTGTGGCATCCTCAACGAGAGTCAGGAGAAGATGATGACTCACGTGGAGAATGTGGATTCCGCTTGCTTTGGCGTTGAAGTCTATGTGGAACTTTTAAGGGATGCCTATGTCTGTGAATATTGCTCAGCTTACTTTAAGCAGAAAACAGATTTGCGGGCTCATCGCGATTCGGGCATACACAAGGATGGCTTCTGTTGGTGTCAGCCGTGTGGCAAGGAGTTTAATGACATGAAAATCTATCGTCATCATATGCGCAATTTTCAGCAACAACGAGCGGATGTTGAACATCGCAAGCTGGAGATTTGTCTTCACTTTATGTGCGATTATGAAAATTGCTATGAGTCGTACGTCAATTGGAATTCCTTGTACACGCACAAGAAACGCACTCACAATGTGGTCGACAAGGAGATGTCTACGTCAAAGGCCATCGAATGGATCTGTCAGTTCTGCCAGAAGGTTTGTCGCTCCAAAATGTCGCTATCGGTGCATGTGGCACGCAGTCACAACAATAATAACGTAATTTGTCCGATCTGCAATGCTTCGTACAAGGATGACGAGGCGTTAAAGAAGCATCACGCCTATTGGCATGAGCCCATGAAGTGTGAGCTGTGCCTGAAAGTGGTCAAGAATCGTCGCAACTTTGACACACACATGAATGTGGTGCACTCGAATAATAAGCGCTATGGCTGCAACATCTGCAAGAAGGGATTCTACCACAGGAGCGAAATGGAGGCGCATAAGCGACTTCATTCACAATTGTACGGCTGCGGACAGTGCAGCTTCACCACGAGGAACAAGCAATCATTGTCGGTTCATGTGCTTGGCCAGCATTACAAGAGTTTTGCCTTTGAGTGTTCTATCTGCAATAAGCATTTTGGACGTCGTCAGGGCTTGACCAAGCATATGCAAAGTGTCCATGGCTCCAAGAATACTTGTCGTGATTACTATGACGGTGGCTGCAGCAAAACCTTTAACACAATCGCACAATTAAACGTGCACGTGCGTAAAGTACATGATGGCAGCATTGTACTTCCAGAGGAGGACGAGCAGGAGGAGGATCAGGATGAGCAGCAGGATCACGAAGAACATGAGGAGGAGCACGATGAGCCGATAGAGGATgaacaggagcagcagcaggaccGAAAACCGTTGCTTAACgtttcaacagcagcatcgACATCAAAGAAACGATGCATACGCATCAGCGATACACACATCGAGTTCATAAGCGCCGATCCCGAAGAGGATAACACTACGGACATCACGGATGCGAAAAACCTTGAGCAAATTGAAGAAACCAAATACAAACCGCCTccagcaaaaaagaaaaggaaacaGAGTTAA
Protein Sequence: MSENLKTNNKAEPSCLHCRVHNSKQPFQEIFDEVGIEIELPDLLAKYFQINVKPDPKKQQLLCEECVKTLIRFFDIDELQREQDAAKDKNKKQTKIEKTPSAAVKRETRPSKKQTPPTNKTKSEPKKLTTSVKLATLEATPPAKAAPPSKASPPAEPVSMRITRGKSATASQKRTQINAKSKPSEKSKEAGTGEQEQISELLRDILDEEKTPPDDKSKEGATTRVRKKETKVAVVEKQAEQEEGETDKQQENVDELEFLLESGDGTSDLEIRQFKVEKQTSIDTAQSQSEDESLKVEPFNFVLIKESDDIEDLYAYLATVVKTCFETLTFDWSTVCCHCSLKCSKFETLLAHMQKCHQLPEEHYKCPIEECNSELHSYKFLAMHLVLLHAPVADIPIYGSCPECHMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCNYADTNIDELFQHLHYSHEPEGTLFCDLCDRYFRDPAVFTDHNKTHSNVNSITFVCTICSASFETRGRLSNHIRATHGSIISCELCCREFATEASYNMHMKKHLIIEREVHVCSNCGILNESQEKMMTHVENVDSACFGVEVYVELLRDAYVCEYCSAYFKQKTDLRAHRDSGIHKDGFCWCQPCGKEFNDMKIYRHHMRNFQQQRADVEHRKLEICLHFMCDYENCYESYVNWNSLYTHKKRTHNVVDKEMSTSKAIEWICQFCQKVCRSKMSLSVHVARSHNNNNVICPICNASYKDDEALKKHHAYWHEPMKCELCLKVVKNRRNFDTHMNVVHSNNKRYGCNICKKGFYHRSEMEAHKRLHSQLYGCGQCSFTTRNKQSLSVHVLGQHYKSFAFECSICNKHFGRRQGLTKHMQSVHGSKNTCRDYYDGGCSKTFNTIAQLNVHVRKVHDGSIVLPEEDEQEEDQDEQQDHEEHEEEHDEPIEDEQEQQQDRKPLLNVSTAASTSKKRCIRISDTHIEFISADPEEDNTTDITDAKNLEQIEETKYKPPPAKKKRKQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00585484; iTF_00602079; iTF_00586183;
90% Identity: iTF_00585484;
80% Identity: -