Dsub013849.1
Basic Information
- Insect
- Drosophila suboccidentalis
- Gene Symbol
- -
- Assembly
- GCA_037043435.1
- Location
- JBAMBK010002317.1:1276800-1280498[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 16 4.7 3.4e+02 2.2 0.0 1 23 368 393 368 393 0.89 2 16 0.021 1.5 9.7 1.8 2 23 404 425 404 425 0.93 3 16 6.5 4.7e+02 1.8 3.0 2 17 436 451 435 462 0.75 4 16 0.011 0.79 10.6 0.4 3 23 495 515 493 515 0.96 5 16 6.3e-05 0.0046 17.6 0.4 1 23 523 546 523 546 0.97 6 16 0.071 5.1 8.0 1.5 2 23 551 572 550 572 0.96 7 16 0.00079 0.058 14.1 0.5 1 23 620 644 620 644 0.91 8 16 2.2 1.6e+02 3.3 0.7 3 21 651 669 651 670 0.88 9 16 0.046 3.4 8.6 1.3 1 23 689 714 689 714 0.95 10 16 0.013 0.97 10.3 1.4 2 23 730 752 729 752 0.93 11 16 0.0045 0.32 11.8 0.2 3 23 759 780 757 780 0.92 12 16 0.026 1.9 9.4 0.3 2 23 784 806 783 806 0.96 13 16 0.00038 0.028 15.1 1.7 3 23 814 834 812 834 0.97 14 16 0.029 2.1 9.2 0.6 1 23 838 861 838 861 0.93 15 16 1.1e-05 0.0008 20.0 2.3 1 23 867 890 867 890 0.97 16 16 0.0036 0.26 12.1 0.2 5 23 903 922 895 922 0.90
Sequence Information
- Coding Sequence
- atgtcggagaatttgaaaataaataaagccgAACCTAGTTGCCTGCATTGCAGAGTGCACAACTCAAAACAGCCATTTCAGGAGATATTCGATGAAGTGGGAATTGAAATCGAACTGCCCGATCTGCTGGCCAAATATTTTCAGATAAATGTCAAACCCGATGCAAaaaaacagcagctgctgtgcgAAGAGTGCGTTAAAACCTTAATTCGTTTCTTCGACATCGATGAGCTGCAGCGGGAACAGGATGCGGCCAAGGATAAGAACCAGAAGCACACCAAGAATGAGAAAACTCCATCGGCTGCTGTTAAAAGGGAAACGAGCCCCAGTAAAAAACAAACGCCGCCAACGAACAAAGCTAAAAATGAACCTAAAAAGTTGCCAACTTCTGTAAAGTTGGCAACGCCAGAGGCTGCTCCTCCTTCAAAGGCTGCTCCTCCAGCAAAGGCTTCTCCTCCCGCTGAACCAGTTTCCATGCGCATCACCAGGGGAAAATCAGCAACAGTGACACAAAAACGAACCCAGATCAATGCCAAATCCAAGCCAAGTGAAAAGTCCAGTGGGAAGGCGGAAGGTAAACGGCACGGCTCCAAGGAAGCAAGAACAGGAGAGCAGGAGCAGATAAGCGAGCTCTTGCGTGACATTCTGGATGATGACAAATCCAAGGAGGGAGCGACGACAAAAGTGCGTCCGAAGGAGAAAAATGTGGAGAAGCACACGCAACAGGCAGATCAGGAGGAGGGAGAGACGGACAAGCAGCAGGATAATGCTGATGAGCTCGAGTTTCTGCTGGAGCCTGAAGATGGCTCCTCTGACTTGGAGATCCGTCACTTCAAGGTGGAGAAGCACACATCAGTTGACACCGCACAATCGCAAAGCGAGGATGAATCCCTCAAAGTGGAGCCCTTCAACTTTGTATTAATCAAAGAATCTGATGACATTGAAGATCTGTATGAATACTTGGCAACTGTGGTGAAGACTTGCTTCGAGACCTTGACTTTTGAATGGTCCACGGTGTGTTGTCACTGCTCGCTGAAGTGCAGCAAATTTGAGACCTTGCTGGTGCACATGCACAAGTGTCACCAGCTGCCCGAGGAGCACTACAGGTGCCCCATTGAGGAGTGCAACGCCGAGTTGCCCAGCTACAAATTCTTGGCCATGCATTTAGTTTTGCTGCATGCCCCTGTGGCGGACATACCCATTTATGGCAGCTGCCCCGAGTGCAACATGACCTTCTCCAATATATTGCAGTACAATAAACACTCCTGCGCCCATGTCATCAAGAAGCGTCGTGGCATTCGCTTGTATTGCGAAATGTGCGGCTTGGAGTTCCCCTCATGGAAGCGCTTTAACTTTCACAATCAGTTCCACTTGGAGAGGCATCGACCACGTGCCTGTTTTGTGTGCAATTATGCGGACACCAACATCGATGAACTGTTCCAGCATTTGCATTATTCACACGAACCCGAAGGCACGCTCTTCTGTGATCTCTGTGATCGCTATTTTCGTGATCCTGCCGTCTTCACGGATCACAATAAAACCCATTCGAATGTCAACAACATCACATTCGTCTGCACCATTTGCAATGCCAGCTTTGAGACACGGGGACGTCTCAGTAACCACATACGCTCCACGCATGGATCCATCATTAGCTGTGAGCTGTGCTGTCGAGAGTTTGCCACGGAGGCTTCCTACAATATGCACATGAAGAAGCATCTGATCATTGAGCGTGAGGTGCATGTGTGCAGCAATTGTGGCCTTCTCAACGAGAGTCAGGAGAAGATGATGACTCACGTGGAGAATGTGGATTCCGCTTGCTTTGGCGTTGAAGTCTATGTGGAACTTTTAAGGGATGCCTATGTTTGTGAATATTGCTCAGCTTACTATAAGCAAAAGACAGATTTGCGGGCTCACCGGAATTCAGGCATACACAAGGATGGTTTCTGTTGGTGTCAGCCGTGTGGCAAGGAGTTTAACGACATGAAAATCTATCGTCATCATATGCGCAACTTTCAGCAACAACGAGCGGATGTTGAACACCGCAAGCTGGAGATTTGCATCTACTTTATGTGCGACTATGAAAATTGCTTTGAGTCGTACGTCAATTGGAATTCCTTGTACACGCACAAGAAGCGCACTCACAATGTGGTCGACAAGGAGATGTCGACGTCAAAGGCCAACGAATGGATCTGTCAGTTCTGTCAGAAGGTTTGTCGCTCCAAAATGTCGCTATCGGTGCATGTGGCACGCAGTCACAACAACAATAATATAATTTGCCCGATCTGCAAGGCGTCGTATAAGGATGACGAGGCGTTGAAGAAGCATCACGCCTATTGGCATGAGCCCATGACGTGTGCGCTGTGCCTGAAAGTGGTCAAGAATCGTCGCAACTATGACACACACATGAATGTGGTGCACTCGAATAATAAGCGTTATGGCTGCAACATCTGCAAGAAGGGATTCTACCACAGGAGCGAAATGGAGGCACATAAGCGATTGCATTCACAATTGTACAGCTGCGGACAGTGCAGCTTCACCACGAGGAACAAGCAATCATTGTCGGTACATGTGCTTGGCCAGCACTACAAAAGTTTCGCCTTTGAGTGTACTATCTGCAATAAGCATTTTGGACGTCGTCAGGGCTTAACCAATCATATGCAACGTGTCCATGGCTCCAAGAATACGTGTCGTGATTACTACGATGGTGGCTGcagcaaaacatttaataCAATCGCCCAGTTGAACGTGCACGTGCGTAAAGTACATGATGGCAGCATTGTCCTTCCAGAGGAGGACGACCAGGAGGAGGATCAGGATGAGCAGCAGGATCACGAAGAACACGAGGAGGAACACGAGGAGCACGATGAGCAGAATGAGGATGAAccggagcagcagcaggatcGAAAATCGACACCATCGACATCAAAGAAACGTTGCATACGCATCAGCGATACACACATCGAGTTCATAAGCGCCGATCCCGAAGAGGATGACAATACGGACATTACGGAAGCGAAAAACCTTGAGGAACTCGAAGAAGCCAAATACAAACCGCCGCCagccaaaaagaaaaggaaacagagctaa
- Protein Sequence
- MSENLKINKAEPSCLHCRVHNSKQPFQEIFDEVGIEIELPDLLAKYFQINVKPDAKKQQLLCEECVKTLIRFFDIDELQREQDAAKDKNQKHTKNEKTPSAAVKRETSPSKKQTPPTNKAKNEPKKLPTSVKLATPEAAPPSKAAPPAKASPPAEPVSMRITRGKSATVTQKRTQINAKSKPSEKSSGKAEGKRHGSKEARTGEQEQISELLRDILDDDKSKEGATTKVRPKEKNVEKHTQQADQEEGETDKQQDNADELEFLLEPEDGSSDLEIRHFKVEKHTSVDTAQSQSEDESLKVEPFNFVLIKESDDIEDLYEYLATVVKTCFETLTFEWSTVCCHCSLKCSKFETLLVHMHKCHQLPEEHYRCPIEECNAELPSYKFLAMHLVLLHAPVADIPIYGSCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCNYADTNIDELFQHLHYSHEPEGTLFCDLCDRYFRDPAVFTDHNKTHSNVNNITFVCTICNASFETRGRLSNHIRSTHGSIISCELCCREFATEASYNMHMKKHLIIEREVHVCSNCGLLNESQEKMMTHVENVDSACFGVEVYVELLRDAYVCEYCSAYYKQKTDLRAHRNSGIHKDGFCWCQPCGKEFNDMKIYRHHMRNFQQQRADVEHRKLEICIYFMCDYENCFESYVNWNSLYTHKKRTHNVVDKEMSTSKANEWICQFCQKVCRSKMSLSVHVARSHNNNNIICPICKASYKDDEALKKHHAYWHEPMTCALCLKVVKNRRNYDTHMNVVHSNNKRYGCNICKKGFYHRSEMEAHKRLHSQLYSCGQCSFTTRNKQSLSVHVLGQHYKSFAFECTICNKHFGRRQGLTNHMQRVHGSKNTCRDYYDGGCSKTFNTIAQLNVHVRKVHDGSIVLPEEDDQEEDQDEQQDHEEHEEEHEEHDEQNEDEPEQQQDRKSTPSTSKKRCIRISDTHIEFISADPEEDDNTDITEAKNLEELEEAKYKPPPAKKKRKQS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00534097;
- 90% Identity
- iTF_00585484;
- 80% Identity
- -