Dleo014763.1
Basic Information
- Insect
- Drosophila leontia
- Gene Symbol
- -
- Assembly
- GCA_008042735.1
- Location
- VNKB01002017.1:37272-40889[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.011 0.97 10.1 3.5 2 23 325 347 324 347 0.95 2 17 0.22 19 6.0 0.1 1 23 354 379 354 379 0.94 3 17 0.063 5.4 7.8 4.0 2 23 390 411 390 411 0.93 4 17 0.082 7 7.4 0.1 3 23 452 473 451 473 0.95 5 17 0.0036 0.31 11.7 0.4 3 23 481 501 479 501 0.95 6 17 0.0048 0.41 11.3 0.2 1 23 509 532 509 532 0.98 7 17 0.0053 0.45 11.1 0.3 2 23 537 558 536 558 0.97 8 17 0.0001 0.0087 16.5 0.7 1 22 606 627 606 630 0.91 9 17 0.31 26 5.6 1.4 3 21 637 655 637 656 0.90 10 17 0.0031 0.26 11.9 0.6 1 23 675 700 675 700 0.97 11 17 0.2 17 6.2 1.3 2 23 718 740 717 740 0.93 12 17 0.0064 0.55 10.9 0.5 2 23 746 768 745 768 0.92 13 17 0.015 1.3 9.7 0.2 2 23 772 794 771 794 0.95 14 17 6.5e-05 0.0056 17.2 0.6 1 23 800 822 800 822 0.97 15 17 0.0075 0.64 10.7 0.9 1 23 826 849 826 849 0.93 16 17 1.2e-05 0.0011 19.4 1.4 1 23 855 878 855 878 0.97 17 17 2.1e-05 0.0018 18.7 0.1 1 23 882 910 882 910 0.87
Sequence Information
- Coding Sequence
- ATGTCggaaaaccagaaaaacacaaatagCTGCCTGCATTGTACTGTTTTCAATACGAAATACCAGTACCAGGAGATCTTCGATGAGTTTGGCAGGGAACTGGGCCTCCAAACGCTGCTGGCCAAGCATTTCCAGCTGGATGTGGCGCCCGATCCGCGCCAGCGTCAGCTCCTGTGCGAGGTGTGCGTCAACACACTCATCCGGCTGTTTGATATCGATGAACTGCAGCGGCAACAGGATGCGGCAAGGGCTAGGTTCAAGGATCCAAGTCCTGAAACTGTTGTCATCCTGGATTCAGTCGAGCCTGACGTTAAGCCTGCGCCCAAGAAGGAAAAGATTGTGAAACCcacagctgctcctcctcctcctcctcccttaAGGGAACCAAGTGCACGGATCAGTAAGAGAGTTCAGCCACCTCTGGTAGTGCCTGTTCCATCGAAATTGTCGGAAAGTGCCAAGGAGACGGTGAAACCCGAAAAGGATGCATCGCCCGCCAAGCCAAAGGATGCAGATCAGGAGCATATCAGTGTGCTCATACAAAACCTTCTCGATGAAGACGAGGCCATAAACGAGGAAGTGGCCGACGAAGCTGAGTCCTTTTGTGAGGAAGTAGAAGCCATAGAAGCTGCTCCCATTCCAGAGGAGCCGCAAACCCAAAGAAAAATTGTCTTGTTGAACAAGAAAGCTGGGCTTCAGCCTAGTCTAGATGAAGATATTTACATATACGAGCATGAGGATATCCTGGAGCCAGCTGTAAAGAAGGTAAAGGTCGAAGTCAAGGATCGATCTTCAGCTAAGGAACAAGTGCAAGCGGAGGAGAGCCAAAGCGAGGGTGAAACCGAGGAGAGTCATGTGGTGCTCTTTGACTTTGTTATGATCAAAGAAAAGGATGACATTGCTGACATTGCCGAGTACTTGTCCACGGTGGTAAAGACCAGCTTTGAAAAGCTTACCTTTGAATGGACCACGACTTGCAAACACTGTTCCCAGAAGTTTCCTAACTTTGAGAGCCTTTTAAGTCACACACTAAAGTCGCATAAATCTCGAGGCAATGTCTACAAGTGTCCCATTGATGGCTGCAGCAAGGAGTTGAAGGGCAGCAAATTTCTGGCCATGCATTTGGTTGTCTTACATGCTCCCGTAGCTGAAATACCCATTTATGGCAGTTGTCCGGAGTGCAAAATGactttttctaatatattGCATTACAACAAACACTCTTGTGCTCATATGATTAAAAAGAAGCGCGGTGTTCGCTTATTTTGTGAAATGTGTGCTCAGGAATTTCCCTCCTGGAAGCGttttaACTTTCACAATCAATTCCATTTGGAGAAGCATAGGCCTCGCGCCTGCTTTGTCTGTGATTatgccagcaacaacattgATGAGCTGTTTCAGCACTTGAACTACTCCCATGAGCCTGTGGGCACTTTGTTTTGCGACCTtTGCGATCGCACTTTCCGGGATCCCGGGGTGTTCATGGAGCACAATAAGTCGCATGCCAATGTGAGCAGCACTACTTATTCCTGCGGCGAATGCATGGCAGTATTTGAGTCACGAAGTCGCCTAAATGGACACATGcGCTCTATGCATGGCAGCATAATTAGCTGCGAGCTTTGTTCCCGCGAGTTTGGCAGCGAGGCCACCTACAGCATTCACATGAAGAAGCATCTGATTATCGAGAGAGATCTGCACGTTTGCCACAATTGCGGCCTGCTGAACGATAGCCAAGAAAAGATGGCTGAACATGCAGAAACCAAGAATTCGCCCTGTTTTAAGGCCAAGATATACACAGAGATGCTACGCGATGCCTATGTCTGTGAATACTGTTCCTCGTACTTTAAGCAAAAGTCCGATTTGCAGGCACATCGCCAGTCGGGAATCCATAAGAATGGTTTGTTTTGGTGCCAGCCGTGTGGCAAGGATTTTCCCCATATGAAACTGTACCGCCATCACCTGCGCAACTATCAGAAATTGCGATCGGATTCAACGCATCGTAAGCTAGAGATTTGTGTCTTTTACATGTGCGATCAGCAGGACTGCACGGAGGCCTATGTGAACTGGAACTCGTTGTACACGCACAAGCGACGCACTCATGAATCATCAGATAAGCAGACGGAGAAGGCCTCAAAGTCTGCCCAGGCTTGGATTTGCCAGTTTTGCTTAAAGGAGTGCCGCTCAAAGATGTCCTTGTCTGTTCATGTGGCTAGAAGTCATAATAATGACAACGTCTCCTGTTCCTTGTGCAATGCCTCTTATAAAAGCCAGGATGCTTTGGACAAGCACCATGCCTACTGGCATGAGCCCATCGAGTGCCCGCAATGCTTTAAGATTGTTAAAAATCGTCGAAATTACGACACTCATGTTAATGTTGTGCATTCAAACAAGAAGCGCTATGCCTGCGGTGTTTGCGAAAAGGGTTTTTATCATAAAAGCGAAATGGAGGCTCATCAAAAGCTCCATGGCCAGTTGTACAGCTGCGAGCAGTGCAGCTTCACCACAAGAAACAAGAAGTCATTGTCGGTTCATGTCCTTGGCCAGCACTACAAGCGTTTTGCCTTCGAGTGCAAAGTGTGCAACAAGAGATTCGGACGTCGTCAGGGCCTGACTACGCACATTCAGCGGTCTCATGGCTCCAAGTACGTTTGCCGTGACTACTTTGAGGCAGGCTGCGGGCGCACCTTTGTCAGCAGTTCCCAGCTTAATGTTCATGTGCGGAAAGTCCACGAAGGCAGTATTTTTCTAcaagaagaggaggaggaagaagaGGACAGCGATGGGCCATCCACATCCAAGAAGCCCTGCTATAGCATCGATGATGATAGCAATATTGAGTTTGTAGAAATTGGAGACggcgaggatgaggaggaggagatggtggaggaagaggaggaagaaTTTATTGACGATCCCAATTTGGATACTAAACATTAA
- Protein Sequence
- MSENQKNTNSCLHCTVFNTKYQYQEIFDEFGRELGLQTLLAKHFQLDVAPDPRQRQLLCEVCVNTLIRLFDIDELQRQQDAARARFKDPSPETVVILDSVEPDVKPAPKKEKIVKPTAAPPPPPPLREPSARISKRVQPPLVVPVPSKLSESAKETVKPEKDASPAKPKDADQEHISVLIQNLLDEDEAINEEVADEAESFCEEVEAIEAAPIPEEPQTQRKIVLLNKKAGLQPSLDEDIYIYEHEDILEPAVKKVKVEVKDRSSAKEQVQAEESQSEGETEESHVVLFDFVMIKEKDDIADIAEYLSTVVKTSFEKLTFEWTTTCKHCSQKFPNFESLLSHTLKSHKSRGNVYKCPIDGCSKELKGSKFLAMHLVVLHAPVAEIPIYGSCPECKMTFSNILHYNKHSCAHMIKKKRGVRLFCEMCAQEFPSWKRFNFHNQFHLEKHRPRACFVCDYASNNIDELFQHLNYSHEPVGTLFCDLCDRTFRDPGVFMEHNKSHANVSSTTYSCGECMAVFESRSRLNGHMRSMHGSIISCELCSREFGSEATYSIHMKKHLIIERDLHVCHNCGLLNDSQEKMAEHAETKNSPCFKAKIYTEMLRDAYVCEYCSSYFKQKSDLQAHRQSGIHKNGLFWCQPCGKDFPHMKLYRHHLRNYQKLRSDSTHRKLEICVFYMCDQQDCTEAYVNWNSLYTHKRRTHESSDKQTEKASKSAQAWICQFCLKECRSKMSLSVHVARSHNNDNVSCSLCNASYKSQDALDKHHAYWHEPIECPQCFKIVKNRRNYDTHVNVVHSNKKRYACGVCEKGFYHKSEMEAHQKLHGQLYSCEQCSFTTRNKKSLSVHVLGQHYKRFAFECKVCNKRFGRRQGLTTHIQRSHGSKYVCRDYFEAGCGRTFVSSSQLNVHVRKVHEGSIFLQEEEEEEEDSDGPSTSKKPCYSIDDDSNIEFVEIGDGEDEEEEMVEEEEEEFIDDPNLDTKH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00593985;
- 90% Identity
- iTF_00527478;
- 80% Identity
- -