Dleo016130.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila leonis
Gene Symbol
RREB1
Assembly
GCA_035045365.1
Location
JAWNPC010000934.1:1561757-1568176[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0059 0.44 11.3 0.6 1 21 254 274 254 276 0.96
2 13 0.00034 0.025 15.2 0.2 1 23 286 308 286 308 0.98
3 13 8.1e-05 0.0061 17.2 7.3 1 23 314 336 314 336 0.98
4 13 0.26 19 6.1 2.2 2 19 540 557 540 559 0.97
5 13 0.0089 0.67 10.7 0.1 1 23 710 732 710 732 0.97
6 13 1.2e-05 0.00093 19.7 0.7 1 23 742 764 742 764 0.99
7 13 0.00083 0.063 14.0 2.0 1 23 770 793 770 793 0.97
8 13 0.003 0.22 12.2 2.0 1 23 1044 1067 1044 1067 0.95
9 13 8.7e-05 0.0065 17.1 0.3 2 23 1408 1429 1407 1429 0.97
10 13 0.15 11 6.9 6.3 1 23 1435 1458 1435 1458 0.97
11 13 2.4 1.8e+02 3.1 3.8 1 23 1582 1605 1582 1605 0.88
12 13 0.0085 0.64 10.8 0.5 3 23 1664 1684 1662 1684 0.96
13 13 0.0013 0.1 13.3 4.8 1 23 1690 1712 1690 1712 0.99

Sequence Information

Coding Sequence
atGCTGgccacacagcaacaacagcagcagcagccacaacagcaacatacagcagcaacagcagcagcggcagcggcagcagcagtaactcTTGAGGATGCGGTTATGGAGCGACAGCGTCGTGATTCCAGCACCTCGGAGTCATCGCTGGAGCATCTGGATCTGGGTCGCACGCCAAAgaagctgagcagcagcagcggtgcGCCGCAGCCGACGTCGACGCCACATGTTGAGGCGACGTCGCGGAAGCGCAAgatgcggcagcagcagcaacagcagcagccgcaaatCTTGTACTCTGACGAGGAGgaggaacaacagcagcaacagcagcagcagcagcaacagttgctggaGCAGTCGGTGCATCGCATTCGCCACAAGCAGCGCCGCAGCGGCAATgcagtcgctgccgctgccagcgcCAGCATCGTGGTCGACTACAGCGTCGGCAGCGATGCCAGTTCGCTGCGCAAAAAGTTTCGTCTGAATCGGAGCAGCATCAGCGCTCACAACGGCGACCTGTCCGAGTCGGGCTTCGTCGATGGCAGCGCACACAGCGGCTATTTGCTAAGCgccagcagcgcagcgcagtcGGCGAcgacagcgcagcagcagcagcagcagcagcagcagcagcaacagcaacagcagcagcagcagccgggtTCGGGCAGCAGCTCGGGCGGCTCCTCGCCGCAAGGCCTGTGCCATTCGAGCGCCGAGTCCGGCATCGGCGCTGGCGACGACCACATGAAATATGTCTGCCCCATCTGCGAGGTTGTCTCGGCCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTATGCCAACGGCGACACCGAGAACTTCACCTGCCGCATTTGCTCCAAGGTACTCTCGTCCGCCTCCTCGCTGGACAGACACGTCCTGGTGCACACCGGGGAGCGACCCTTCAACTGTCGCTATTGCCACTTGACCTTCACGACCAACGGCAACATGCATCGCCACATGCGAACACAcaagcaacatcaacagcagcagcagcagcaacagtcacagcaacagtcacagcagcagcagccgcagcaagcacagcagcagcaacagcagcagcagcagcaacagttgcagcgaCATCAGCAACATGCGGTGGCTCAACGTGCCGAGAGCTATGAAAGCGATGCCAGTTGCTCCACGGATATAtccagtagcagcagcagtgcagccagcaacaacaacaacaacaacagtagccaagcgaacaacaacaacaacagccaggaggagcagcaactgttgctggcgtgcaagcagcaacagctgaaaacaaacatcaacaacaacaacatcattgTAAGCGATGAGCGAGCATTGGATGcagatggcgatggcgatggggAGGTCGATGGAGCTGGCGACGATGGGGAGAGCGTGGATGTGACACAGATGATAACGAGCACACCGGACGTGGCCACATTGCTGGCCACATCGTCGGGCAACAGCAGCCCGAGGACGCCAGAGCAGGAGTCGGCGGCGCTGCCCAGTTGCCCCGTCTGCAGTGCCGATGAGTTCGAGACGCTGGCAGCGGTGTACGCCCACCTGGAGACGGAGCATGCCGACATACCCGCCAAGTGTCGGGAGTGCGAGGTGATCTTTGCCACACAGCGTCAGCTGCAGGCGCATTGCTGTCGGGGCTTGCagttgccgccgctgctgggCGCCAGCTCCTCGCCGCTGCACAAGCAGGAGCCggcggaggaggaggatgaagagcagcagcaacagcacgaAGACGAGGCCGATGCCGATGAGGATGCGGATGAGGATGAGATGCGGCTGCAGGCGAACAGCGAACGCGATGAGTTCTTTCAGCAACTGTATCTGAAGGGCAAGTCGGGCAGCTGCTCGTTGCCGTCGCCCATCAAGCATGAGCCGTCGGAGCAGCGCCAGGATCTGGCCGACATCCAGAGCATTCTGCACATgaccagctccagctgcacgTCCAGTTTCCTGCGCAACTTCGAGCAGAACGTGAACACGCCATGCTCCAGCCAGTACAGCCTGGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAGCGAGTTCCGGCGCATGAAGCTGCGCGGCGAATTCCCCTGCAAACTCTGCTCCGCCGTCTTTCCCAATCTGCGCGCCCTCAAAGGCCACAACCGCGTCCATCTGGCGGCTGTGGGCGCTGCCGGCCCCTTCCGCTGCAACATGTGTCCCTACGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGCGACCGGCCATACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGTCACCTGCGCAATCGGCATGGCAAAACGAGCCGCGATGAGGTAAAGCGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGTGAGGAGATCAAGCCCAAAATGGATCCGGATCTGTCAGAGCTCAGCTTTCGTTCGCTCAGTCCGTCGCCATCGACGACAAATGTCGAGTCGAACTCGCAGCTGAAACACATGTTGCTGGCGGAGCAGcccagcaaacagcagcagcagcagcagccagcgcaGCCTCCACTGAAGATTCAGGTGAAGAGCCTCGATCAGCTGGTGGAGAAGCCGCTGGCAGCCGTCATGGATCTCAGCATGGATGTGCTGGATCTAAGCAAGAAACCGCAACGCGAACATGACTTActcttgcagcagcaacagcaacagcagcagcagcagcagcaacagcagcagcaacagcagcaacagcagcagcagcaacagttgctctTCAATCCAGGTGATGCAGCCACGCAGtatatgcagctgctgcgcaatTTGATGCTGCAGCAATCGTCCGGCTTTCCGTTCTTTGGGCTGATGGCGCcgccgccagctgctgctgctgctgctgcactggagAAGTCAGtgccagcagcaatggcagtgccagcaacagttgcagctgcagctgcagtgccGTCGCCTTTGGgcatgccattgccattgccagtgCCAGCAGCCGGGCCCGTCAAGATGGTCATCAAGAACGGCGTGCTGATGCCCAAGCAGAAGCAGCGTCGCTATCGCACCGAGCGGCCCTTCGCCTGTGAGCACTGCTCGGCGCGGTTCACCCTGCGCTCCAACATGGAGCGGCACgtcaagcagcagcatccgCAGTTCTATGCGCAGCGCCAGCGCAGCGGGCATCATGTAATGCGTGGGCGGGCGGCCAACTCGGGTGCagcgcaagcagcagcagcagcggcagcagcagcagcagcagccgcagcagcagccatgacaaatctgcagcagcagcagcagcaacatcagcagcaacagcagcagcaacatgcgcACATCTCGGAGCATGTGAAGTATGCAATCTTGGCGCAGCAGCTGAAGGCGCGCAAGGATACAGATTTGCTGCAGCAGGCGCGCAAGGACACGGACCTGTTGCAGCAGGCGCTGGCGCATGGCTCCAGCAATGTTGTCGTCAATCCATTGCTGCACTtcagctacaacagcaacaacagcaacagcaacagcaatggcaatggcagcaatcaggcgccgcagcaacagttgcccgTGGATGATGATGAGCCGCCGAAGCTGATCATAGACgaagatgatgaagatgagTTTGATGACATagacgaggaggaggaggaggaggaggaggatgaagAGTTTGAGCAAgacgaacagcagcagcagcagcagcagcaggaagagcagcagcaacacgagcaacagcaacatgtgGAGCAAGTGCAGCCAATTGATGAAATTGTTGCCAAAGATGAGCTTGAGCCGCCCACTGAGTTGGCTGAGGCCAAACTGCAGCCAAGTGGCGAGCCAACGACCATGAAGACTATGATTGCCCAGGCCGAGTCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGCTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTACTTTCGGCCCAGCGATGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagctgcagcgagcCCAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAATCGTGTCAGCTGTCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTCACCCACACCGGCCAGAAGCCATTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCATGGCAACGTGGAGTCCGCCATGTCGGTCTACGTGCCCACCGAGGATGTCAGCGAGCCCATACCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGTCGCCGCAAGGCGGCCGAAAAGGAGCgtcagctggagctggagcgtGAGCGGGAGCGCGAACGTGAGCTGGAGCGGGAACGTGAGCTGGAGCGGGAgcgcaagcagcaacagctcatCCAGCAGCTGACGGCAGCGGCACAGCTCAGCCAGCAGATGGTGGCAGCGGCTCaggctgctgccgcagcagctgccaacaccagcaccaccagcaccaccgccgccgccgccgccagcaCCGTCGAGGCCAATGGCAGCGAGCTGCCCTACAAGTGCCACCTGTGCGAATATTCGTTTGGCGAGCGGATGCAGTGCCTCGATCACATTAAGCAGCTGCATGCCCAGGAgtttgcgctgctgctggccaaagGCGCCATCGAAACGGAGCAGgagacagcaacagttgctgctgctgctgctgctgcagccaccTCGGCTGCCATCTCTGAGGATGAGTCGAGCACTGGACGCAGCTCCGGCAAATATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGTCGCTTCTGGTCCACGGAGGATCTGCGTCGCCACATGCGCACCCACTCGGGCGAGCGGCCCTTCCAGTGCGAGATCTGCCTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACGCAGCCACAATGGCGAGGCGGGCGCCTCCGACTGCTCCGATGATGAGCAAATGGCAACGCCGCCAACAACACCAAcgcccacagccacagccatggccatgcccatgcccatgccaatgcccagcaacaacaacaacaacaacaatacttgccacaacaacaacaacaatagcaacaacaagagctcACGTCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCGAACGAGTGGCGCGTCAGCCGCCTCGGCGAGCACAAGGAAAACATTGCCGAATCCTCGAcggccacaacagcagcagctgtgggcgtggccagcggCGATTTCCTGGGCAATCTGCTGGGCATCACCGATCAGGGCATACTCAACAAGCTGCTCAGCTCGCCCGACGAGGCGGCCAAATTGCTGGGCGTCGAAAAGTGA
Protein Sequence
MLATQQQQQQQPQQQHTAATAAAAAAAAVTLEDAVMERQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHVEATSRKRKMRQQQQQQQPQILYSDEEEEQQQQQQQQQQQLLEQSVHRIRHKQRRSGNAVAAAASASIVVDYSVGSDASSLRKKFRLNRSSISAHNGDLSESGFVDGSAHSGYLLSASSAAQSATTAQQQQQQQQQQQQQQQQQQPGSGSSSGGSSPQGLCHSSAESGIGAGDDHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQQQQQQSQQQSQQQQPQQAQQQQQQQQQQQLQRHQQHAVAQRAESYESDASCSTDISSSSSSAASNNNNNNSSQANNNNNSQEEQQLLLACKQQQLKTNINNNNIIVSDERALDADGDGDGEVDGAGDDGESVDVTQMITSTPDVATLLATSSGNSSPRTPEQESAALPSCPVCSADEFETLAAVYAHLETEHADIPAKCRECEVIFATQRQLQAHCCRGLQLPPLLGASSSPLHKQEPAEEEDEEQQQQHEDEADADEDADEDEMRLQANSERDEFFQQLYLKGKSGSCSLPSPIKHEPSEQRQDLADIQSILHMTSSSCTSSFLRNFEQNVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEEIKPKMDPDLSELSFRSLSPSPSTTNVESNSQLKHMLLAEQPSKQQQQQQPAQPPLKIQVKSLDQLVEKPLAAVMDLSMDVLDLSKKPQREHDLLLQQQQQQQQQQQQQQQQQQQQQQQQQLLFNPGDAATQYMQLLRNLMLQQSSGFPFFGLMAPPPAAAAAAALEKSVPAAMAVPATVAAAAAVPSPLGMPLPLPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAAAMTNLQQQQQQHQQQQQQQHAHISEHVKYAILAQQLKARKDTDLLQQARKDTDLLQQALAHGSSNVVVNPLLHFSYNSNNSNSNSNGNGSNQAPQQQLPVDDDEPPKLIIDEDDEDEFDDIDEEEEEEEEDEEFEQDEQQQQQQQQEEQQQHEQQQHVEQVQPIDEIVAKDELEPPTELAEAKLQPSGEPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEKERQLELERERERERELERERELERERKQQQLIQQLTAAAQLSQQMVAAAQAAAAAAANTSTTSTTAAAAASTVEANGSELPYKCHLCEYSFGERMQCLDHIKQLHAQEFALLLAKGAIETEQETATVAAAAAAAATSAAISEDESSTGRSSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEAGASDCSDDEQMATPPTTPTPTATAMAMPMPMPMPSNNNNNNNTCHNNNNNSNNKSSRLPKLHELLDKANEWRVSRLGEHKENIAESSTATTAAAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00512904;
90% Identity
iTF_00559679;
80% Identity
-