Basic Information

Gene Symbol
Aef1
Assembly
GCA_035045355.1
Location
JAWNPB010000133.1:12530944-12532036[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0059 38 4.6 0.1 21 48 185 212 178 216 0.86
2 4 2.4e-05 0.16 12.2 0.0 21 52 213 244 210 245 0.89
3 4 0.027 1.8e+02 2.5 0.1 21 48 241 268 239 272 0.85
4 4 7.3e-05 0.47 10.7 0.1 21 47 269 295 264 302 0.88

Sequence Information

Coding Sequence
ATGATGCATATCAAGAGCCTGCCACACGCACATCAGGCCGCCGCGGCAATGAGCAATTGCGACATTGTCATTGTTGCCGCGCAACCGCAGACCAccagcgccaacaacaacaacaatgatacTGTTACACAGGCAAGCCATGCCAGCCATGCGGCAGCTcaacaacaacaacagcagcaacaacaacagcaacaacaacaacagcagcaacaacaacagcaacacaatcaacagcaacaacaacagccgcccGCGCCTACAGAAATCGCCCTACCCTTTAACATGCATTTGAGCGGAATTTCAGCGGAGGCACACAGTGCTGCCCAGGCGGCCGCAATGGCAGCTGCGCAGGCCGCGGCAGCGCAAGCCGCCGCCGCGGATCAACAGCCAACAGCACCTCCCGCGCCACCCTCGGCACACACGCTGGCTCACCTGGTGGCCAATGCTACGCATAGTCCGACGCTTGGCGAGTCGCACTATGTGAGCAACGGTCACTCCAACAACGAGCATTCGGGCGAGGGTAATGGCTcgagcggcagcggcggccggGAGCCGGAGAAACCGTTCCATTGCACAGTGTGCGATCGACGATTTCGCCAGTTGAGCACATTGACCAACCACGTGAAGATCCATACCGGCGAGAAGCCCTACAAATGCAACGTTTGTGATAAGACGTTCCGTCAATCGTCAACGCTGACGAATCATTTGAAAATTCATACCGGCGAAAAACCATACAATTGCAACTACTGTCCCAAGCATTTCCGTCAGCTGAGCACTTTGGCCAATCATGTCAAGATTCATACGGGTGAAAAGCCGTTCGAGTGCGTCATATGCAAGAAACAATTCCGCCAATCCAGCACGCTCAACAATCACATAAAGATCCATGTTATGGACAAGGTCTACGTTCCTGTCAAGATCAAAACGGAGGAGGACGAGGGGTGA
Protein Sequence
MMHIKSLPHAHQAAAAMSNCDIVIVAAQPQTTSANNNNNDTVTQASHASHAAAQQQQQQQQQQQQQQQQQQQQQHNQQQQQQPPAPTEIALPFNMHLSGISAEAHSAAQAAAMAAAQAAAAQAAAADQQPTAPPAPPSAHTLAHLVANATHSPTLGESHYVSNGHSNNEHSGEGNGSSGSGGREPEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNYCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEDEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00473280;
90% Identity
iTF_00516652;
80% Identity
iTF_00531169;