Basic Information

Insect: Drosophila lacicola
Gene Symbol: -
Assembly: GCA_035045355.1
Location: JAWNPB010000049.1:3126647-3130571[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00047 0.032 14.8 0.1 1 23 160 183 160 183 0.96

2 15 0.0016 0.11 13.1 2.9 2 23 232 254 228 254 0.89

3 15 0.014 0.95 10.2 0.9 1 23 361 384 361 384 0.93

4 15 0.58 39 5.1 5.8 2 23 433 455 432 456 0.95

5 15 0.0037 0.25 12.0 0.5 1 23 517 540 517 540 0.88

6 15 2.3 1.5e+02 3.2 0.1 2 14 559 571 558 583 0.85

7 15 0.00078 0.053 14.1 3.3 2 23 591 613 591 613 0.96

8 15 0.00089 0.06 13.9 0.1 1 23 720 743 720 743 0.95

9 15 9.5e-05 0.0064 17.0 0.3 1 23 798 821 798 821 0.93

10 15 0.0013 0.089 13.4 2.2 2 23 871 893 870 893 0.97

11 15 0.0021 0.14 12.8 2.0 1 23 978 1001 978 1001 0.92

12 15 0.15 10 6.9 1.5 1 21 1053 1073 1053 1074 0.95

13 15 0.58 39 5.1 0.1 2 23 1117 1141 1116 1141 0.80

14 15 8.1 5.5e+02 1.5 0.4 1 9 1159 1167 1159 1183 0.68

15 15 3.4 2.3e+02 2.6 0.5 15 23 1218 1227 1215 1227 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00047	0.032	14.8	0.1	1	23	160	183	160	183	0.96
2	15	0.0016	0.11	13.1	2.9	2	23	232	254	228	254	0.89
3	15	0.014	0.95	10.2	0.9	1	23	361	384	361	384	0.93
4	15	0.58	39	5.1	5.8	2	23	433	455	432	456	0.95
5	15	0.0037	0.25	12.0	0.5	1	23	517	540	517	540	0.88
6	15	2.3	1.5e+02	3.2	0.1	2	14	559	571	558	583	0.85
7	15	0.00078	0.053	14.1	3.3	2	23	591	613	591	613	0.96
8	15	0.00089	0.06	13.9	0.1	1	23	720	743	720	743	0.95
9	15	9.5e-05	0.0064	17.0	0.3	1	23	798	821	798	821	0.93
10	15	0.0013	0.089	13.4	2.2	2	23	871	893	870	893	0.97
11	15	0.0021	0.14	12.8	2.0	1	23	978	1001	978	1001	0.92
12	15	0.15	10	6.9	1.5	1	21	1053	1073	1053	1074	0.95
13	15	0.58	39	5.1	0.1	2	23	1117	1141	1116	1141	0.80
14	15	8.1	5.5e+02	1.5	0.4	1	9	1159	1167	1159	1183	0.68
15	15	3.4	2.3e+02	2.6	0.5	15	23	1218	1227	1215	1227	0.89

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCAGCCGATTTCGAAGAGGGTGACGGTGAGTTAGAGAGTCACAATAACGGTAACAGCGCGCTGGCAGACGAGTTTATGGGcgaagaggaggaggacgaACAGGAAGCTGAAGAGGATGAGAGGACGGGTGAAGACAGAGACAGCAAGCGAAAAGGACACGAGCCCGATGACGATGccatatttgattttgaactAGAGCCAATTGTTAGCATTGCGGAACCAGAACCGGAATCTGTGCCAAGACCAACGGTCCCCCTGGCGCCACCAATGCCAACGGGTCCAGCCATCCGACCACAGCACCGCCAATCGTTGCCAGCATCGTTTGGCTCCCAGTTGATAGTGGGTCGCGGCGTTGCAGGCGTTCCACCCACACGGCCAACGACCTCACAAATCAATGCAACCGATGAGAACGGTGTGCCCATTAATTATGAGCTGGGCGTCATCTATATATGCCCCGCCTGCGGCGCCGAGTATCGGCAGCAGGACATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAATACGCGACGGGGTCTCAATTTCGTGGCCATTGATAAGCTATATCATCGGTGCTTGGAATGCAATAAGCGCATCGCAATGCACAGTCGGGAGAATCTGCTGAAGCACAAGTTTACCCATTTGCCATACCGCTGCACCAAGTGCTACATTTGTAAGCGCGAGTACAAGTACAGGCAGGACCTGATGGTGCATTTGCGCATGGTGCACTGTGACGAAGTGGTGGCTATGATGCGCGGCGGTGATGCCAGTGCCGGACGCAAGACACGTGTGCGCGAGCCGCGCATTGAGCAGCATCACGGGCAGCATTACGGGCCGGAgcatgacgatgacgacggcATAGAGGTCAAGAATGAGCTGATGCTGGAGGCGGAGGGCGGCGCGCAGGCAGCTGATGAGTCCAACTTTGGTCTGGATGATGAGCACAGTCGCAGTTCCAGTCAAGCGGCTAGGAAAAAGCGCGGCACTGCTGTGGCTGGCAATGGAAGTGGAAGCGGTGCTGCAGACATATGCGAAGATTATATACACTATATGTGTCCCGACTGCGGCACCGATTGCGATACGCACGCCCAATGGAGTCAACATATTGAATTTGTGCATGACTATGTCAGTCGGCGCGGGCTGAACTTTCGCTGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAGCAGTTTGTCATTCCGAACACGATAAAGACGCTGCGTGCGCACAAGTTTGGCCATTTACCTCAGCCGGAGTGGATGCGCTGCAAGCTGTGCTATCAGGGCTTTACGGAGCATCATGAGCTGCTCACGCATCTACTGAAGCAGCATCATTTGGAAACCCTAATGCCTGAAAAGGAGGAGGAGCAATCCTTGGCCACAGTTGGTGCGGGTGATGAGGGCGAGGATACTCAAGGCATTGGCGGCGATGAGGAATCTCAGTTGCAATGGGACGATGTGCCGCGTCGTGGCGGTCGCATTGGCAGCGACGATATGTACGAGCCGCATATTGATTATCTGTGTCCGCAGTGCGGCAGGGAGTTTATAGAGAAGAAGCACTGGCGCACACATGTTGTCCAGGTGCACGGCATGAACGATCTGGCCAAGTTGAACTTCGAGGTGATCAACGATCGCCAGCTGAAGTGCACCGAGTGCGATAAGATCATAACGAATGCCTATGGCATACAGAATGCCCAGCAGCACAGGATAACGCATTTGCCGTACAAGGCGTACGCGAGATGCCGTAAATGCCATAAATCCTACACGGATCGCAAGGGTCTGGTCAAGCATTTGGCCACATACCATCGCGTTGGCTATGAACCACGCAAAGCGGGCGCCGTACTAGGCACTGGCACACCGTTGGTCATGGCCTTAAACCCAGCCAAATCACAGACGCCGCGCAAACAAATTGTCACTGTGGCCAACGAAACCTATGAGATTATATATTTGGATGAGGAGCAATCGCCGccaagtaataataatattaatgaagaGAATGACTTTGGAGAGCAAATGCAGgcggatgatgatgattatgcCATCGTAGGCAGCACCAGCGGCAGCATGGGacgccagctgctgccaccaattgccgctgctgccgagGCACCAAATCCCAATCGCTACAAATGCGTCGACTGCGGCTCACTGTTTGCCACGCAGGCGGCGCTGAAGACACACATCAGCGAGGAGCATGATTTCATGGACACACAGTATAGCGCCAAAAAGTTTGATAATGCGGAGCCCTCAGAGgagccagctccagctccagctgcaccTGTTGCCGTGACGACAACAGCCACTGCTATGCCCGTCAAAAACAGCGCCGGAGCCTCGACCATAGAACAGAATTATATATTCCTGTGCCCGTCATGCGGCAAGGCCTACAAGACGCAGTTCGAGTGGCGACGTCACATCAACGAGGAGCACAATTTTGACAAGCGACAATACTTAAATATGCGCCAGCTGGATAAGTATCGCTATCAGTGCACCCTGTGCAAGGACATTGTGTGCAATTCGAAGCTGAAAGGCCTGCAGGATCATCATTTTCGTCATTTGCCTTATCGCCTGTATCTGAAGTGTCTGGTGTGCGGCACCTGCTACAATCACAAGCCCAACATTGCGGCACATCTGCGCACACGACACAACATCTACGAACGCGAGTCCTCGTGGCGTGAGCACCAACCCAAGACCCAGAATGGCTACGAACAGCTCAAGTATAAGGATAAGGATAGGGACATGCAGACCATGGCAGGCACCAGCTCAGGATCACCAACGCCGGGCAGCAGTCGCACGCTCAAACCACAACCGGGCGTGCTGCCCACGCGACCCGCTGGCCTCAATACGCTGGAGGACAGCATCTCGTATCATAATGCCGTGGATCTGGACTTTATTACCTACTATTGCCCCAAGTGCAACAAGAACTTTGATTCGCACGCCTTCTGGCGCAAACACATTGTCGAGCAGCACAACTATAACAGTCGGCAGGGCTTGAACTTTCGCCAGATTGACAACCATCACTATTTGTGCCTGGAGTGCTATAAGCGTGTGACTGTGACTCACACCAAGGGCGCAATTGGGCAGCTGCAGTCGCACAAGTTCCGGCATTTGCCGTATCGCTCCTTTAAGTGCTTGACCTGCAGCGGCGAGTTTGTGCGCAAGCAAATGTTCTTCAAGCATTTGAATCGGGACACCAATCGCTGTGACAACAAGCCAATGAGTTGCCAGGATAATGATGAGGATACAGCAGAACAGCCGGATAGGCCAGTTGCCATGCCCGTTAAGGCGGCACCTGATGGCGCCACGTATCGTTTGATGTGCCCGCAGTGCGGTGATGGCTtcaccaccagcagcaaagCACTCTGGCGGgagcatataaatatctatcaTGGTCTGGGCAAGCGCGATCTGCTGCATATGCGTAAACTGGGCGAGGAACTGTATCGCTGCACAGACTgtgaggagcagctgcagacCAAACAGTTGCgcgtgctgcagcagcatcgcTTCCAGCATTTGCCCTATGCCGCCTATATACGCTGCCAGCTGtgcgaacagcagcagccgccggaTGGACTGGGTCATGGTGCAGCCGCTGCCGGATTACATAGTATGcgcgagctgcagcagcacatgCGTACCGAGCACCCCAATGTGACGGAGCATGATGACCAAATGCAAGCGCTGCTGGATGAGGAGGAGCTGGAAGATGTTCAGCAGCCGGCGGCGAACAGTGAGACGTCGGACAATGGTCCATATATGCCATTACCGCCGCATTTGCTGGACGATGATGTCGAGGACATGGAGTTCGAGGAGCAGTATCTGCTGGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDGELESHNNGNSALADEFMGEEEEDEQEAEEDERTGEDRDSKRKGHEPDDDAIFDFELEPIVSIAEPEPESVPRPTVPLAPPMPTGPAIRPQHRQSLPASFGSQLIVGRGVAGVPPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRGGDASAGRKTRVREPRIEQHHGQHYGPEHDDDDGIEVKNELMLEAEGGAQAADESNFGLDDEHSRSSSQAARKKRGTAVAGNGSGSGAADICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFGHLPQPEWMRCKLCYQGFTEHHELLTHLLKQHHLETLMPEKEEEQSLATVGAGDEGEDTQGIGGDEESQLQWDDVPRRGGRIGSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKAGAVLGTGTPLVMALNPAKSQTPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAIVGSTSGSMGRQLLPPIAAAAEAPNPNRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEPSEEPAPAPAAPVAVTTTATAMPVKNSAGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERESSWREHQPKTQNGYEQLKYKDKDRDMQTMAGTSSGSPTPGSSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGEFVRKQMFFKHLNRDTNRCDNKPMSCQDNDEDTAEQPDRPVAMPVKAAPDGATYRLMCPQCGDGFTTSSKALWREHINIYHGLGKRDLLHMRKLGEELYRCTDCEEQLQTKQLRVLQQHRFQHLPYAAYIRCQLCEQQQPPDGLGHGAAAAGLHSMRELQQHMRTEHPNVTEHDDQMQALLDEEELEDVQQPAANSETSDNGPYMPLPPHLLDDDVEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00551114;
80% Identity: -