Dlac012523.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila lacicola
Gene Symbol
ftz-f1
Assembly
GCA_035045355.1
Location
JAWNPB010000251.1:3454938-3469170[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.55 5.3e+03 -3.5 21.1 47 167 26 155 5 160 0.56
2 3 1.5e-19 1.5e-15 57.7 0.4 1 79 320 397 320 420 0.75
3 3 2.5e-72 2.4e-68 231.5 1.2 157 408 527 771 495 773 0.90

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCCACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCGTTTAGCATGCAGCtcgaccagcagcagcccgcGAGTCCAGCGCagagcaacaccaacaacaataacagtaacAATAACAGTGGCAATAACAGtggcaataacagcagcagcaacaacaacaacgataacgaAACAAATGCTTTGAGCAATTCCGATAACGATTACAGCGCCTACACGCTGCAATTGGGcaatcatcagcagcagcagcaacaacaacaacaacatcacacgcatcaccagcagcagcaacaacaacattaccaacaacaacaacagcaacagaatattgccagcaacaacacgaaTGCCGCGAACCAATTCAACGCCTCCTCCTACtcgtatatatacaatttcgATTCACAGTATATATTTCCGACAGGGTATCAGGAAACGAACTCATCTCATTCGCAGCAGAGCGGCAATGGAGCCGGCAACGCGGTGGCTGGCAACTCTGGCCAGCTGCTgaacggcggcagcggcggcgctGGGGGCAACGGTTATATGCTGCTGCCACCGGGCGCTGGTGGCGCCTCGGCTGCACACATGTCCGGCAGCGTGGGCGGCAGCGGTGCGGCGGGCGGCGCTGGCGGTGCGGGTGGCGCTGGAGGGGGCCATCATGGCGGGACGAGCGCCAGCTCGGGCGGCGGCGAGGCCATCGACTTTAAGCACCTGTTCGAGGAGCTGTGCCCCGTCTGCGGCGACAAGGTGAGCGGCTATCATTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTTCAGAACAAAAAGGTCTACACTTGCGTTGCGGAGCGCTCCTGCCACATCGATAAAACGCAGCGCAAACGTTGTCCATATTGTCGATTCCAAAAGTGCCTGGAGGTGGGCATGAAACTAGAAGctgttcGAGCGGACCGCATGCGCGGCGGTCGGAACAAATTTGGACCCATGTACAAGCGGGATCGGGCGCGCAAGCTGCAGGTGATGCGTCAGCGGCAACTGGCGCTGCAGGCGCTGCGCAGTTCGATAGGCACGGACATAAAGCCGACGCCGCTCTCGCCGGGCTATCAGCAAGCATATccaaatatgaatattaagcAAGAAATTCAAATACCTCAGGTATCCTCACTCACGCAATCGCCGGACTCGTCGCCCAGCCCCATTGCGATCGCCTTGGGTCAGGTGAATGCAGGCGCGGGCGGTGTGATAGCCACGCCCCTGAATGCGGGCAATTTGAGCGGCGGCAACGGGAACGGCGGCAGCTCCTCGCtgggcaatggcaacaacaacaccaacaacaacagcacaggcagcggcagcggtggcGGGGGCAGCGGAGGAGGCAACaacgccggcggcggcggcgtcggcggcggtggcagcaacaatcTCGCCGACGGCCTGCAACGAAACGGAAAcagtggcaacagcaacagcaacagcagttgccACGAAACCGGACCTGGATCTCTGCAGAACACAGCCGAATCGAAATTGTGCTTTGATTCTGGCACACATCCATCGAGCACAGCCGATGCGCTCATCGAGCCACTGAGGGTCTCGCCGATGATACGTGAGTTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAGCTCTTTGCGCTGCTGCAGAAGCAGACGTATAACCAGGTGGAAGTGGATCTCTTTGAGCTAATGTGCAAAGTGCTGGATCAGAATCTGTTCTCGCAAGTGGACTGGGCAAGAAACACGGTCTTCTTTAAGGACTTGAAGGTGGACGATCAGATGAAGCTGCTTCAGCACTCGTGGTCGGACATGCTCGTGCTGGATCATCTGCATCATCGCATACACAACGGCCTGCCGGATGAGACGCAGCTGAATAACGGGCAGGTCTTCAACCTGATGAGCCTGGGCCTGTTGGGTGTGCCGCAGCTGGGCGACTACTTCAACGAGTTGCAAAATAAGCTGCAGGACCTCAAGTTCGATATGGGCGACTATGTGTGCATGAAATTCCTAATACTTTTAAATCCAGATGTGCGTGGAATCGTGAACAAAAAGACCGTCGTGGAGGGCCACGAGAATGTGCAGGCTGCGCTGCTGGACTACACACTAACGTGTTATCCCTCGGTTAATGACAAATTCAGGAGGCTTTTGAACATACTACCGGAAATTCACGCCATGGCCGCACGGGGCGAGGAGCACCTTTACTCGAAGCACTGTGCCGGCAGTGCGCCCACGCAGACGCTGCTTATGGAGATGCTGCATGCCAAGCGGAAAGTGTAA
Protein Sequence
MLLEMDPQQATVQFISSLNLSPFSMQLDQQQPASPAQSNTNNNNSNNNSGNNSGNNSSSNNNNDNETNALSNSDNDYSAYTLQLGNHQQQQQQQQQHHTHHQQQQQQHYQQQQQQQNIASNNTNAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSGNGAGNAVAGNSGQLLNGGSGGAGGNGYMLLPPGAGGASAAHMSGSVGGSGAAGGAGGAGGAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNAGAGGVIATPLNAGNLSGGNGNGGSSSLGNGNNNTNNNSTGSGSGGGGSGGGNNAGGGGVGGGGSNNLADGLQRNGNSGNSNSNSSCHETGPGSLQNTAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVVEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00485910;
90% Identity
iTF_00547388;
80% Identity
iTF_00531004;