Basic Information

Insect: Drosophila kurseongensis
Gene Symbol: -
Assembly: GCA_018153305.1
Location: JAECXX010000004.1:5691483-5695015[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.1 7.4 7.2 2.6 2 23 323 345 322 345 0.94

2 18 2 1.5e+02 3.1 0.0 1 23 352 377 352 377 0.87

3 18 0.031 2.3 8.8 2.2 2 23 388 409 388 409 0.93

4 18 0.099 7.3 7.2 0.1 3 23 450 471 449 471 0.95

5 18 0.0039 0.29 11.6 0.3 3 23 479 499 477 499 0.95

6 18 0.0089 0.66 10.5 0.4 1 23 507 530 507 530 0.98

7 18 0.00052 0.039 14.4 0.3 2 23 535 556 534 556 0.97

8 18 0.062 4.6 7.9 0.1 1 19 564 582 564 585 0.93

9 18 0.0014 0.1 13.0 0.4 1 22 604 625 604 628 0.91

10 18 0.32 24 5.6 1.4 3 21 635 653 635 654 0.90

11 18 0.0084 0.63 10.6 0.5 1 23 673 698 673 698 0.96

12 18 0.045 3.3 8.3 1.5 2 23 716 738 715 738 0.93

13 18 0.001 0.077 13.4 0.2 2 23 744 766 743 766 0.92

14 18 0.039 2.9 8.5 0.1 2 23 770 792 769 792 0.95

15 18 7.3e-05 0.0054 17.1 1.0 1 23 798 820 798 820 0.98

16 18 0.0026 0.19 12.2 0.9 1 23 824 847 824 847 0.94

17 18 0.00024 0.018 15.5 1.2 1 23 853 876 853 876 0.97

18 18 2e-05 0.0015 18.8 0.2 3 23 882 908 880 908 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.1	7.4	7.2	2.6	2	23	323	345	322	345	0.94
2	18	2	1.5e+02	3.1	0.0	1	23	352	377	352	377	0.87
3	18	0.031	2.3	8.8	2.2	2	23	388	409	388	409	0.93
4	18	0.099	7.3	7.2	0.1	3	23	450	471	449	471	0.95
5	18	0.0039	0.29	11.6	0.3	3	23	479	499	477	499	0.95
6	18	0.0089	0.66	10.5	0.4	1	23	507	530	507	530	0.98
7	18	0.00052	0.039	14.4	0.3	2	23	535	556	534	556	0.97
8	18	0.062	4.6	7.9	0.1	1	19	564	582	564	585	0.93
9	18	0.0014	0.1	13.0	0.4	1	22	604	625	604	628	0.91
10	18	0.32	24	5.6	1.4	3	21	635	653	635	654	0.90
11	18	0.0084	0.63	10.6	0.5	1	23	673	698	673	698	0.96
12	18	0.045	3.3	8.3	1.5	2	23	716	738	715	738	0.93
13	18	0.001	0.077	13.4	0.2	2	23	744	766	743	766	0.92
14	18	0.039	2.9	8.5	0.1	2	23	770	792	769	792	0.95
15	18	7.3e-05	0.0054	17.1	1.0	1	23	798	820	798	820	0.98
16	18	0.0026	0.19	12.2	0.9	1	23	824	847	824	847	0.94
17	18	0.00024	0.018	15.5	1.2	1	23	853	876	853	876	0.97
18	18	2e-05	0.0015	18.8	0.2	3	23	882	908	880	908	0.84

Sequence Information

Coding Sequence: ATGTCGGAAAACGCAAAAAACAATAGCTGTCTGCATTGCTCCGTATTCAGTACGAAATACCAGTACCAGGAGATATTCGATGAGTTTGGAATCGAGCTGGGTCTCCAATCCTTGCTGGCCAAGCACTACCAGGTCGATGTCGCACCCGATCCTCAGAAAAAGCAGCTTCTGTGCGAAGTGTGTGTCAATAATCTCATCCGCCTGTTCGACATCGATGAATTGGAGCGGGAAAGGGATGCAGCCAAGACAGTGGACCAGGATGAGGCGCCCAAGCATCCCATTATCATCACCGATGTCGAGGCATCGCAACCTGCAGCGAAGCCAGCTAAGAAGGCAACGCCACCAAAGCCCCTGGCAAAGGTCCTGCGCCCTGTACCCATAGCCCCCACACGGGAACCAAGTGCCCGCATCAACAAAGGAATTCCGGCGCCCCAGTTAACGCTTTGTTCATCTAAGCCTCCTGCCCGATCCAAGGATCCTCCACAGAAAGGTCCCCCCATTCAAATTGAAGCTCCAAAAGATGCGGATCAGGAGCAGATTAGTGTCCTGATACAAAATATCCTGGGCGAAGATGAGACCGTCGCTGAAGAAGTAGCCAGTGAAGTTACCAATTTTCTGATCGCCAAGGAATCGGAAAACCCAGCCGAAATTGTTCTGCTGAACGACGAACCCGAGGCTGAACCTGTTCTAGATGAGGAGGAAGATGTATACATATATGAGCACGAAGATATACTGGACCCAGATTTGGACGATGTAAAGGTCAAATCAATGGTTCGTCCACCCAGATTAGTAGACCAAGCTGAGGAGAGCCAAAGCGAAGGAGAGGATGACGATGGCGAGGCCAGCAATGTGGTTCTATTCAACTTTGTTGATATCAAGGAAAAGGATGACATTGAGGACATTTCGGAGTACTTGTCAACTGTGGTGAAGACCAGCTTCGAAAAGCTAACATTTGAGTGGTGTACAGTGTGCAAACACTGCTCCTTAAAGTGTCCCACATTTGATAGCCTTTTAAGTCACATTGTTAAGGCCCACAAAACCCGAAGAGATGTCTACCAGTGTCCCATTGAAGGTTGCAGCAAGGAGCTAAAGGGTCGCCAGGTTCTTGCCATGCATCTGGTTCTTTTGCACGCTCCCGTGGCTGAGATTCCAATATATGGTAGCTGCCCGGAATGTAAAATGACATTTTCCAACATTTTGCAGTACAACAAGCACTCTTGCGCCCATGTCATAAAAAAGAAACGAGGTGTTCGCACGTTTTGTGAAATGTGCTCCCTGGAGTTCCCATCCTGGAAACGATTCAGTTTCCACAACCAATTCCATCTGGAGAAGCATAGACCTCGCGCCTGCTTCGTCTGCGATTTTGCCAGCACCAACATCGATGAGCTTTTCCAGCATTTAAATTATGCCCATGAGCCAGTGGGCACCTTATTTTGCGACCTTTGCGACCGGACTTTTCGTGATCCTGCCGTGTTCATGGAGCACAACAAGTCGCATGCCAATGTGAGCAGTACAACCTATTCCTGCGGCGAGTGCTTGGCACACTTTGAGTCACGAGGGCGATTAAATGGTCACATGAGAGTCATGCATGGCAGCGTGGTAAGCTGCGAGCTCTGCTCCCGAGAATTTGCCACCGAAGCCACCTACAACATTCACATGAAGAAGCACTTGATTATTGAGCGGGATGTGCACGTGTGCAGCAAATGTGGCCTGGTGAGCGACAGCCGCGAAACGCTTCTTGCCCATGCGGACTCCCCGAAGTCTGCCTGTTTTGGCACTAATATATATATGGAACTGCTTCGTGAAGCTTACGTCTGCGAATACTGCTCATCGTACTTCAAAGAAAAAGAAAATCTTCAAGCACATCGAGAGTCAGGGGTTCATAAAGACGGATTGTATTGGTGTCAGCCCTGCGGCAAGGACTTTCCTCACATGAAACTGTACCGTCACCATCTGCGCAACTATCAGAAACTGCGCTCCGATTCGACGCATCGCAAGCTTGAGATTTGTGTCTTTTATATGTGCGATCAGGAGAACTGCTCGGAGGCATATGTTAACTGGAACTCCTTGTACACACACAAGCGACGAACCCACGAATCTTCAAAAAAACAGGCGGAGAAAACCGCCAAGAGTACCCAAGAATGGATTTGTCAATTTTGTTCAAAGGAGTGCCGCTCAAAGATGTCCTTGTCCGTTCATGTGGCAAGGAGCCACAATAATGACAACGTGGTTTGTCCTTTATGCAAAGCCTCATACAAAAGCCAGGATGCTCTGGCCAAGCACCATGCCTATTGGCACGAACCCATCGAGTGCCCTCAATGTTTTAAAATCGTTAAAAATCTTCGTAATTATGACACTCATGTGAATGTGGTGCATTCGAATACAAAGCGCTACTCCTGCGGTGTCTGTGAGAAAGGCTTCTATCACAGAAGTGAAATGGAGGCTCATCAGAAGCTCCATGGTCAGTCTTATAGCTGCGAGCAGTGTAGCTTCACCACCAGGAACAAGAAGTCCCTGTCTGTTCATATTCTGGGTCAGCACTACAAGCGCTTTGCTTTTGAGTGCAAGGCGTGCAAGAAAAGGTTTGGACGCCGTCAGGGCTTGAGTACCCACATGCAACGAGCACATGGTACCAAGTATATGTGCCGTGATTACTTCGAGGGCGGTTGTGGACGCACTTTTGTAAACAGTTCCCAGCTGAATGTACATGTGCGAAAGGTACACAAAGGTGTCATATTCCTGGTTGAAGAGGACGAATATGTCAGCGACGCGCCATCCACATCTAAGAGGCGATGCATTCGTATTAACGAAGACAATATTGAGTTTATAGAAGATGGAGATGAAGGAGATGATCAGGATGGAATAGAAATGGAAGAAGGTGACGAGGATGAGGAAGAATTTGTCGACGACGTACCAGATAAAGACACCAAGCATTGA
Protein Sequence: MSENAKNNSCLHCSVFSTKYQYQEIFDEFGIELGLQSLLAKHYQVDVAPDPQKKQLLCEVCVNNLIRLFDIDELERERDAAKTVDQDEAPKHPIIITDVEASQPAAKPAKKATPPKPLAKVLRPVPIAPTREPSARINKGIPAPQLTLCSSKPPARSKDPPQKGPPIQIEAPKDADQEQISVLIQNILGEDETVAEEVASEVTNFLIAKESENPAEIVLLNDEPEAEPVLDEEEDVYIYEHEDILDPDLDDVKVKSMVRPPRLVDQAEESQSEGEDDDGEASNVVLFNFVDIKEKDDIEDISEYLSTVVKTSFEKLTFEWCTVCKHCSLKCPTFDSLLSHIVKAHKTRRDVYQCPIEGCSKELKGRQVLAMHLVLLHAPVAEIPIYGSCPECKMTFSNILQYNKHSCAHVIKKKRGVRTFCEMCSLEFPSWKRFSFHNQFHLEKHRPRACFVCDFASTNIDELFQHLNYAHEPVGTLFCDLCDRTFRDPAVFMEHNKSHANVSSTTYSCGECLAHFESRGRLNGHMRVMHGSVVSCELCSREFATEATYNIHMKKHLIIERDVHVCSKCGLVSDSRETLLAHADSPKSACFGTNIYMELLREAYVCEYCSSYFKEKENLQAHRESGVHKDGLYWCQPCGKDFPHMKLYRHHLRNYQKLRSDSTHRKLEICVFYMCDQENCSEAYVNWNSLYTHKRRTHESSKKQAEKTAKSTQEWICQFCSKECRSKMSLSVHVARSHNNDNVVCPLCKASYKSQDALAKHHAYWHEPIECPQCFKIVKNLRNYDTHVNVVHSNTKRYSCGVCEKGFYHRSEMEAHQKLHGQSYSCEQCSFTTRNKKSLSVHILGQHYKRFAFECKACKKRFGRRQGLSTHMQRAHGTKYMCRDYFEGGCGRTFVNSSQLNVHVRKVHKGVIFLVEEDEYVSDAPSTSKRRCIRINEDNIEFIEDGDEGDDQDGIEMEEGDEDEEEFVDDVPDKDTKH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00515724;
90% Identity: iTF_00588295; iTF_00494540; iTF_00512156;
80% Identity: -