Dkok006658.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kokeensis
Gene Symbol
ftz-f1
Assembly
GCA_035042145.1
Location
JAWNLT010000263.1:11202717-11215307[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 2 1.8e+04 -10.4 28.3 33 160 16 157 4 169 0.60
2 4 0.51 4.5e+03 -3.3 14.8 45 136 91 169 74 201 0.41
3 4 2.1e-19 1.8e-15 57.2 0.7 1 78 331 407 331 429 0.73
4 4 3.6e-72 3.1e-68 231.0 1.8 157 408 531 775 496 777 0.91

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCGTTTAGCATGCAACTcgaacaacagcagcccgcgagTCCGGCGCacagcaacactaacaacgctaacaacaacaacaacaacagttccaacagcaacaacaacaacagcagcagtaatagcaacaacaacaacaacaataacgataacgatacaAATGCATTGAGCAATTCCGATAACGATTACAGTGCATACACTCTGCAACTGGGcagtcatcagcagcagcagcagcaacactcacatcacacacatcaccagcagcagcagcagcagcaacaacagcagcattaccaacaacaacaacaacagaatattgccaacaacaatgcgaatgCAGCGGCGAATCAATTCAATGCTTCCTCCTATtcgtatatatacaatttcgATTCACAGTACATATTCCCGACAGGCTATCAGGAAACGAACTCATCGCATTCGCAGCAAAGTGCAAATGGAGCCGGcaatgctgcagcagctggcaactcTGGCCAGCTCCTGaacggtggcagcagcagctcgacAGGTAATAGTTACATGCTGTTGCCACCGGGCGCTGGTGGcacctctgctgctgccgctgcccatATGTCCGGCAATGTGGGCGGCAATCCGGCCGCGGGCGTAAGTGGAACCGCCGCCGGTGGGGGTCATCATGGCGGCACCAGCGCCAGTTCTGGCGGCGGCGAAGCCATCGATTTTAAGCATCTGTTCGAGGAGCTGTGCCCCGTCTGCGGAGACAAGGTGAGCGGCTATCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACcgttcaaaacaaaaaggtCTACACTTGCGTGGCGGAGCGCTCCTGCCACATCGACAAGACGCAGCGCAAACGTTGTCCATATTGTCGATTCCAGAAGTGCCTAGAGGTGGGCATGAAACTAGAGGCGGTTCGAGCGGATCGGATGCGTGGCGGTCGCAATAAATTTGGACCCATGTACAAACGGGATCGGGCGCGAAAACTGCAAGTGATGCGTCAGCGGCAACTGGCGCTGCAGGCGTTGCGCAGTTCGATGGGCACGGACATAAAGCCGACGCCTCTCTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGgtATCCTCACTCACACAATCGCCAGACTCATCACCCAGCCCCATTGCTATTGCCTTGGGTCAGGTGAATGCGAGCGGGGGCGGTGTGATAGCCACGCCGATCAATgccggcaatggcaacggtgGCTCCTCACTTGGCAATggcggcaatggcaacaacaacaacaccaacaacagcggcaCAGGCAGCGGaagcggaggaggaggaggaggggctGGTGGAGGAGGCAACAATACtggtggcaacaacatcaCCGATGGCCTGCAACGCAAtggaaacagcagcaatagcaacagcaacagcagttgccacGAAATCGGCACTGGATCTCTACAGAACTCAGCCGAAGCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGCCGACGCGCTTATTGAGCCACTCAGggTCTCACCAATGATACGCGAATTTGTGCAATCGATCGATGATCGGGAATGGCAAACGCAACTTTTTGCGCTACTGCAGAAGCAGACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTAATGTGTAAAGTGCTTGATCAGAATCTATTCTCACAAGTGGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTAAAGGTTGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCCGATATGCTCGTGCTGGATCATTTGCATCATCGCATTCACAATGGTCTGCCCGATGAGACTCAGCTAAATAACGGTCAGGTCTTCAATTTGATGAGTCTTGGTCTGCTGGGAGTGCCACAGCTGGGTGACTATTTCAACGAGCTGCAGAATAAGCTGCAGGAACTGAAGTTCGATATGGGCGACTATGTTTGCATGAAATTCCTAATACTGCTAAATCCAGATGTGCGAGGCATTGTTAACAAGAAGACCGTCTTGGAGGGACATGAGAATGTTCAGGCCGCGCTACTGGATTACACACTGACCTGTTATCCCTCAGTTAATGACAAATTCAGGAGGCTACTTAACATCCTTCCGGAAATACACGCAATGGCCGCACGAGGCGAGGAGCACCTCTACTCAAAGCATTGTGCTGGCAGTGCACCCACACAGACGCTGCTCATGGAGATGCTGCATGCCAAGCGGAAAGTGTAA
Protein Sequence
MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNTNNANNNNNNSSNSNNNNSSSNSNNNNNNNDNDTNALSNSDNDYSAYTLQLGSHQQQQQQHSHHTHHQQQQQQQQQQHYQQQQQQNIANNNANAAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSANGAGNAAAAGNSGQLLNGGSSSSTGNSYMLLPPGAGGTSAAAAAHMSGNVGGNPAAGVSGTAAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGVIATPINAGNGNGGSSLGNGGNGNNNNTNNSGTGSGSGGGGGGAGGGGNNTGGNNITDGLQRNGNSSNSNSNSSCHEIGTGSLQNSAEAKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQELKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00485910;
90% Identity
iTF_00508363;
80% Identity
iTF_00528100;