Basic Information

Insect: Drosophila kanekoi
Gene Symbol: -
Assembly: GCA_037075305.1
Location: JBAMCE010000271.1:1525819-1529718[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00046 0.03 14.8 0.1 1 23 160 183 160 183 0.96

2 15 0.0016 0.11 13.1 2.9 2 23 232 254 228 254 0.89

3 15 0.014 0.91 10.2 0.9 1 23 360 383 360 383 0.93

4 15 0.57 38 5.1 5.8 2 23 432 454 431 455 0.95

5 15 0.0036 0.24 12.0 0.5 1 23 516 539 516 539 0.88

6 15 2.2 1.5e+02 3.2 0.1 2 14 558 570 557 582 0.85

7 15 0.00077 0.051 14.1 3.3 2 23 590 612 590 612 0.96

8 15 0.00088 0.058 13.9 0.1 1 23 720 743 720 743 0.95

9 15 9.3e-05 0.0062 17.0 0.3 1 23 796 819 796 819 0.93

10 15 0.0013 0.085 13.4 2.2 2 23 869 891 868 891 0.97

11 15 0.0021 0.14 12.8 2.0 1 23 972 995 972 995 0.92

12 15 0.15 10 6.9 1.5 1 21 1047 1067 1047 1068 0.95

13 15 1.7 1.1e+02 3.6 0.1 2 23 1111 1135 1110 1135 0.74

14 15 2.6 1.7e+02 3.0 0.5 1 10 1153 1162 1153 1177 0.67

15 15 3.4 2.2e+02 2.7 0.5 15 23 1210 1219 1207 1219 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00046	0.03	14.8	0.1	1	23	160	183	160	183	0.96
2	15	0.0016	0.11	13.1	2.9	2	23	232	254	228	254	0.89
3	15	0.014	0.91	10.2	0.9	1	23	360	383	360	383	0.93
4	15	0.57	38	5.1	5.8	2	23	432	454	431	455	0.95
5	15	0.0036	0.24	12.0	0.5	1	23	516	539	516	539	0.88
6	15	2.2	1.5e+02	3.2	0.1	2	14	558	570	557	582	0.85
7	15	0.00077	0.051	14.1	3.3	2	23	590	612	590	612	0.96
8	15	0.00088	0.058	13.9	0.1	1	23	720	743	720	743	0.95
9	15	9.3e-05	0.0062	17.0	0.3	1	23	796	819	796	819	0.93
10	15	0.0013	0.085	13.4	2.2	2	23	869	891	868	891	0.97
11	15	0.0021	0.14	12.8	2.0	1	23	972	995	972	995	0.92
12	15	0.15	10	6.9	1.5	1	21	1047	1067	1047	1068	0.95
13	15	1.7	1.1e+02	3.6	0.1	2	23	1111	1135	1110	1135	0.74
14	15	2.6	1.7e+02	3.0	0.5	1	10	1153	1162	1153	1177	0.67
15	15	3.4	2.2e+02	2.7	0.5	15	23	1210	1219	1207	1219	0.89

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCAGCCGATTTCGATGAGGGCGACGGTGAGGTAGGGAGCCACAATAACGGTAACAGCGCGCTGGCAGACGAGTTTATGGgcgaagaggaggaggaggaacagGAGGCTGAAGAGGATGAGGGGACGGGTGACGACACAGACAGCAAGCGAAAAGGACACGAGCCCGATGACGATGccatatttgattttgaacTAGAGCCAATTGTAAGCATTGCGGAACCAGAACCGGAACCTGTGCCAAGACCAACGGTCCCCCTGGCGCCACCAATGCCAACGGGTCCAGCCATCCGACCCCAGCACCGCCAATCGTTGCCAGCATCATTTGGCTCCCAGTTGATAGTGGGTCGCGGCGGTGCAGGGGTTCCACCCCCACGGCCAACGACCTCACAAATCAATGCAACTGATGAGAACGGTGTGCCCATTAATTATGAGCTGGGCGTCATCTATATATGCCCCGCCTGCGGGGCCGAGTATCGGCAGCAGGACATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAATACGCGACGGGGTCTCAATTTCGTGGCCATTGATAAGCTATATCATCGGTGCTTGGAATGCAATAAGCGCATAGCAATGCACAGTCGGGAGAATCTTCTGAAGCACAAGTTCACCCATTTGCCATACCGCTGCACCAAGTGCTACATCTGTAAGCGCGAGTACAAGTACAGGCAGGACCTGATGGTGCATTTGCGCATGGTGCACTGTGACGAGGTGGTGGCCATGATGCGCGGCGGTGATGCCAGCGCCGGGCGCAAGACACGTGTGCGCGAGCCACGCATCGAGCAGCATCACAGATCCTACGGGCTGGAACATGGCGATGATGACGGCATTGAGGTCAAGAATGAGCTGATGTTGGAGGCGGAGGGCGGCGTGCAGGCAGCCGATGAGTCCAACTTTGGTTTGGATGATGAGCACAGTCGCAGCTCCAGTCAAGCGGTTAAGAAGAAGCGCGGCCCAGCTGTGGCTGGCAATGGATGTGGAAGCGGTGCAGCTGAAATATGCGAAGATTATATACACTATATGTGTCCCGACTGCGGCACGGATTGCGATACGCACGCCCAATGGAGTCAACATATTGAATTTGTGCACGACTATGTCAGTAGGCGAGGGCTGAACTTTCGCTGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAGCAGTTTGTCATTCCGAACACGATAAAGACGCTGCGGGCGCACAAGTTTAGCCATTTACCTCAGCCGGAGTGGATGCGCTGTAAGCTGTGCTATCAGGGCTTTACGGAGCATCATGAGCTGCTCACGCATCTACTGAAGCAGCATCATTTGGAAACCCTAATGCCTGacaaggaggaggagcagtCCTTGGCCACAGACGGTGCGGGTGATGAGGGCGAGGATACTCCAGGCATTGGCGGCGATGAGGAATCTCAGTTGCAGTGGGACGATGTGCCGCGACGTGGCGGTCGCATTGGCAGCGATGATATGTACGAGCCGCATATTGATTACCTGTGCCCGCAGTGCGGCAGGGAGTTTATAGAGAAGAAGCACTGGCGCACACATGTTGTCCAGGTGCACGGCATGAACGATCTGGCCAAACTGAACTTTGAGGTGATCAACGATCGCCAGCTGAAGTGCACCGAGTGCGATAAGATCATAACGAATGCCTATGGCATACAGAATGCCCAGCAGCACAGGATAACACATTTGCCATACAAGGCGTACGCGAGATGCCGTAAATGCCATAAATCCTACACGGATCGCAAGGGCCTGGTCAAGCATTTGGCCACATACCATCGCGTCGGCTATGAACCACGCAAAGCGGGCGCCGTActaggcacaggcacaggcccGCCATTGGTCATGGCCTTAAACCCGGCCAAATCGCAGCCGCCGCGCAAACAAATTGTCACTGTGGCCAACGAAACCTATGAGATTATATATCTGGATGAGGAGCAATCGCCGCCAAGTAATAACAACATTAATGAGGAGAATGACTTTGGGGAACAAATGCAggcggatgatgatgattatgccATCATGGGCAGCACCAGCGGCAGCATGGGACGCCAGCTGCCATCAATTGGCGCTGCTGCCGAGGCACCAAATCCCAATCGCTACAAATGCGTGGACTGCGGCTCACTGTTTGCTACGCAGGCGGCACTGAAAACCCACATCAGCGAGGAGCATGATTTCATGGACACGCAGTATAGCGCCAAAAAGTTTGATAATGCGGAGCCCTCAGAGGAGGCAGCCACACCTGCGCCAGTTGCCGTGACGACAGGATCCGGTGCTTTGCCCGCCAAGAACAGCGCCGGCGCCTCGACCATAGAACAGAATTATATATTCCTGTGCCCGTCGTGCGGCAAGGCCTACAAGACGCAGTTCGAGTGGCGACGTCACATCAACGAGGAGCACAATTTTGACAAGCGACAGTACTTAAATATGCGCCAGCTGGACAAGTATCGCTATCAGTGCACCCTGTGCAAGGACATTGTGTGCAATTCGAAGCTGAAAGGACTACAGGATCATCATTTTCGTCATTTGCCTTATCGCCTATATCTGAAGTGTCTCGTGTGCGGCACGTGCTACAATCACAAGCCCAACATTGCTGCGCATCTGCGCACACGACACAACATCTACGAGCGCGAGTCCTCGTGGCGTGAGCACCAACCCAAGACCCAGAATGGCTACGACCAGCCCAAGTATAAGGATAAGGAGAGAGACATGCAGACCAGCTCAGGATCACCAACACCCAGCAGCAGTCGCACGCTCAAACCACAACCGGGCGTGCTGCCCACGCGTCCCGCTGGCCTCAATACCCTGGAGGACAGCATCTCGTATCATAATGCCGTGGACCTGGACTTTATTACCTACTATTGCCCCAAGTGCAACAAGAACTTCGATTCGCACGCCTTCTGGCGCAAACACATTGTCGAGCAACATAACTATAACAGTCGGCAGGGCCTGAACTTTCGCCAGATTGACAACCATCACTATTTGTGCCTGGAGTGCTATAAACGTGTGACTGTGACTCACACCAAGGGGGCAATTGGGCAGCTGCAGTCGCACAAGTTCCGGCATTTGCCGTATCGCTCCTTTAAGTGCTTGACCTGCAGCGGCGAGTTTGTGCGCAAGCAAATGTTCTTCAAGCATCTGAATCGGGACACCAATCGTTGTGACAACAAGCCAATGAGTTGCCAGGATAACGATGAGGATACAACAGAACAGCCGGACAGGCCGGTTGCCATGCCCGCTAAGGCATCACTTGATGGCGCCACGTATCGTTTGATGTGCCCGCAGTGCGGTGATGGCttcaacaccagcagcaaagCGCTCTGGCGGGAGCACATAAATATCTATCACGGTCTGGGCAAGCGCGATTTGCTGCATATGCGCAAGCTGGGCGAGGAACTGTATCGCTGCACAGACTGTGACGAGCAGCTGCAGACCAAACAGCTGCgcgtgctgcagcagcatcgcttccagcatttgccctATGCCGCCTACATACGTTGCCAGCTGtgcgaacagcagcaaccgccGGATGGGACTGGTGCAGCCGCTGCCGGATTGCATAGTATGcgcgagctgcagcagcacatgCGGACCGAGCACCCCAACGTGGCGGAGCAGGATGATCAAATGCAAGCActgctggaggaggaggaggtggacGAAGTTCAGCAACCGACGGCTAACAGTGAGACGTCGGACAATGGTCCATATATGCCATTGCCGCCGCATCTGCTGGACGATGATGTCGAGGACATGGAGTTCGAGGAGCAGTATCTGCTGGGCTAA
Protein Sequence: MEGMDLWTSMFSADFDEGDGEVGSHNNGNSALADEFMGEEEEEEQEAEEDEGTGDDTDSKRKGHEPDDDAIFDFELEPIVSIAEPEPEPVPRPTVPLAPPMPTGPAIRPQHRQSLPASFGSQLIVGRGGAGVPPPRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRGGDASAGRKTRVREPRIEQHHRSYGLEHGDDDGIEVKNELMLEAEGGVQAADESNFGLDDEHSRSSSQAVKKKRGPAVAGNGCGSGAAEICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFSHLPQPEWMRCKLCYQGFTEHHELLTHLLKQHHLETLMPDKEEEQSLATDGAGDEGEDTPGIGGDEESQLQWDDVPRRGGRIGSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKAGAVLGTGTGPPLVMALNPAKSQPPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAIMGSTSGSMGRQLPSIGAAAEAPNPNRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEPSEEAATPAPVAVTTGSGALPAKNSAGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERESSWREHQPKTQNGYDQPKYKDKERDMQTSSGSPTPSSSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGEFVRKQMFFKHLNRDTNRCDNKPMSCQDNDEDTTEQPDRPVAMPAKASLDGATYRLMCPQCGDGFNTSSKALWREHINIYHGLGKRDLLHMRKLGEELYRCTDCDEQLQTKQLRVLQQHRFQHLPYAAYIRCQLCEQQQPPDGTGAAAAGLHSMRELQQHMRTEHPNVAEQDDQMQALLEEEEVDEVQQPTANSETSDNGPYMPLPPHLLDDDVEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00551114;
80% Identity: -