Basic Information

Insect: Drosophila kanekoi
Gene Symbol: L
Assembly: GCA_037075305.1
Location: JBAMCE010000095.1:5939345-5948898[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00075 19.9 2.9 1 23 174 196 174 196 0.98

2 17 0.39 26 5.6 6.2 1 23 202 224 202 224 0.97

3 17 1.9e-07 1.2e-05 25.5 3.2 1 23 230 252 230 252 0.99

4 17 1.4e-05 0.00091 19.6 0.4 1 23 258 280 258 280 0.99

5 17 0.014 0.93 10.1 0.1 2 23 353 377 352 377 0.93

6 17 0.00085 0.056 14.0 0.2 2 23 405 427 404 427 0.95

7 17 0.03 2 9.1 0.7 1 23 498 520 498 520 0.97

8 17 0.0085 0.56 10.8 0.1 2 23 528 549 527 549 0.91

9 17 0.00072 0.048 14.2 0.1 1 23 557 581 557 581 0.94

10 17 7.5 5e+02 1.6 1.6 2 23 617 639 616 639 0.94

11 17 0.0028 0.19 12.3 1.1 1 23 695 718 695 718 0.97

12 17 0.0071 0.47 11.1 1.6 2 23 889 911 888 911 0.96

13 17 0.13 8.4 7.1 0.1 1 23 917 939 917 939 0.92

14 17 0.61 40 5.0 0.4 2 23 947 968 946 968 0.93

15 17 0.82 54 4.6 0.5 2 23 1071 1092 1071 1092 0.94

16 17 0.035 2.3 8.9 0.0 1 23 1102 1124 1102 1124 0.96

17 17 0.00024 0.016 15.7 1.2 1 23 1129 1151 1129 1151 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00075	19.9	2.9	1	23	174	196	174	196	0.98
2	17	0.39	26	5.6	6.2	1	23	202	224	202	224	0.97
3	17	1.9e-07	1.2e-05	25.5	3.2	1	23	230	252	230	252	0.99
4	17	1.4e-05	0.00091	19.6	0.4	1	23	258	280	258	280	0.99
5	17	0.014	0.93	10.1	0.1	2	23	353	377	352	377	0.93
6	17	0.00085	0.056	14.0	0.2	2	23	405	427	404	427	0.95
7	17	0.03	2	9.1	0.7	1	23	498	520	498	520	0.97
8	17	0.0085	0.56	10.8	0.1	2	23	528	549	527	549	0.91
9	17	0.00072	0.048	14.2	0.1	1	23	557	581	557	581	0.94
10	17	7.5	5e+02	1.6	1.6	2	23	617	639	616	639	0.94
11	17	0.0028	0.19	12.3	1.1	1	23	695	718	695	718	0.97
12	17	0.0071	0.47	11.1	1.6	2	23	889	911	888	911	0.96
13	17	0.13	8.4	7.1	0.1	1	23	917	939	917	939	0.92
14	17	0.61	40	5.0	0.4	2	23	947	968	946	968	0.93
15	17	0.82	54	4.6	0.5	2	23	1071	1092	1071	1092	0.94
16	17	0.035	2.3	8.9	0.0	1	23	1102	1124	1102	1124	0.96
17	17	0.00024	0.016	15.7	1.2	1	23	1129	1151	1129	1151	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTAgagaatttaattgaaaagatTCAAGCCACCAAGGAGATTACAAATAACGACATGTACAGCACGCACACCTCCTCCAGCTACTCGCCTAGCATCTCGGACGGCACATTGACGCCCAATtcgcagcagcatcagccacAATTGGCGACAGCTGCCGCGGCACACACATTGGagcccagcagcggcagcggcggaggcggcggcgaGGAGTCGAAGGCGAATGGCGAAGCTGTTGCCGCACAgtcggagctggagcagcaggagcaggaggcaGCCAGACCCAAGCGGCCTGCCCAtttgcatcatcatcatcatcatcattatcatcatcagcaggcGCTGAAAATTGCGAACAAGCTGCGTAAAATCAATAAGGACGCCAAACTGGCAGCTGGTGGCACAGGACCAGGACACGGAACAGCCGCCAAGTTTGATAAGTTGACAGGCGAGGGCATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGaGTCATGCCGAGCATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTCTTCAAGCACAAACGCTCCCGAGATCGTCATAAGAAGCTCCATACGAACGAGAGGAATTACAAGTGTCCGCATTGCGAGGCCGCTTTCTCGAGAAGCGATCATTTGAAGATTCACATGAAGACGCACGACATTCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGGGGCTACAACACGGCCGCCGCTTTAACCTCGCACATGCAGAAGCACAAGAAGAATGCCGCCATCCTGGCAGCTGGCGGCAATCCGAATGCCCTCAACTATAGCCCCAGATCGACGGGCTCCGCTTCCATTTCGAGCAATGGCAGCCTGCACAAGCGTCGCTATGCGTTGGCTCTCGCCTCTGACAGCAGTCCCAGTCGCTTGGACTTTCCCAAACGCTCGCGGGCTCATGTCccgaccacgcccacaccgacaccgctgctgcgctgcagctACTGTCCCAAGGCGACGGAGTTCAGCAGCCTGGAGCAGCTGAATGCACATCTGCAGAGCGCCCACGAGCAGCGAGATTCGCGTAGCTCAAACGCCACGGCTGGCGGGGAGGCAGGGGAGGCTGCGCAGGCGAATGGCTTCCAGCTGAGCTGCGAATACTGCACGATGAAATTTGCGAATATCGCCGCGCTGTTCCAGCACATGCGGGCCACACACTTGGATCGGCTGAGCAGTCCGAACTCCTATTACGAGCACTTCAATCGCCTGGCTACGGCAGGCACATTTAGTCCCAGGCTGGCGCTGGAGCTGCCCAAAATCAAGCAGGACCTGACCAGTCCACAGGCTCAGGCTGCGGAGAAGCCGGAACAGGAGCTGCCCACTGACCTGAGCAGCAATAAGCGTCGCCCCATGACGCCACCGGGCGTCTTCTTTTGCAATCAATGCAATGCCGGCTTGCCGGACTTTGAGAGTTTCCGGAATCATCTGAAGACGCACATAGCCGAGGGCATGCAGCTGATCTGTCCACATTGCGGCCTGAGTCTGCCCGAGCAGAGCGAATACGAACGCCACGTGGTTGCCCATTTCCTGATCAGCAGCTCCGAGTTTAactgcagcgccagctgcggCAAATCCTATGCCAAggccgaggagctgcagcagcacttgCTCAGCGAACACGTGCTCACGATGCTCAAGTGCGCCCTCTGCTCGGAGCTGTGCGAGAATCGGATGTCCATGCAGCTGCATCTGGCCTGTGCGCACAGCCAGGAGTCGAAGTTGCTGCGCTGCAGCGCCTGCCTGGAGCTCTTTCGCAGCGACACGGACTTCCATGTGCATGTCAAGACGCGCCATCAGCTCGATCGTGGATCGGCAAATGGTGGAtcagtcgccgccgccgctgccgctgctgcggctgccgtcTCCGCGCCCGCCAATCCGCTGCAGTGCATGTTCTGTCGGGCCGTTTGTGCCTCGGAGCTGGAAATGCATTTCCACTTGGCCGCACATGCGCGTCAATTCCGTTGTCCCAGCTGCCCGGAAACGTTCCATGTGGAATTTCTGCTCGATCGTCATATGCAGAGCCAGCATGGCGGCGGCGTTAAGGATAAGGAGCCGGGCTCCAATATGGGCAGCCTCTATGTGAATGCGCTGCTACCGCccctggcagctgctgccgctgccgccgccgcggcgaccaacaacaacaacaacaacagcaacctgcACATCGACTACAATGTGGCCTTTAAGGGCCTGTTTGGCGGCACGCCCAGCCCAGCGCAGTCGAACAGCAAATTCTATAGTCCACTGCAGGTGGACACCAGCGCGCTGAAGCCACAGCAAACGCCGCATCCGGCCCTGATGTACGGCCTGAGCCAGCGGTATCTGATGGAAATGTATGCGGCCAAGGCCACATCGCCGGCAGCCAGTGCACCCGAGCTGCCGGCTGCCAGCAGCCAGGCAACGGCCACAGCGTCCAGCGCAGgcgggagcagcagctacagctgcgGCATGTGCGAGCGGCAGGATTTGCGTAGCGAGGCGGAGCTGCATTCGCATCGCAAGCTGGCGCACAATCTGAAGACGGGCGTCAGCCTGAGATGCGCCTATTGCTCCGGCAATTACAAGTCGCGCGccgagctggagcagcacatGAAGAGCTGTCACAATTCGAGCGGCAAGCACAAGTGTCTCATCTGCGATGAGATCTTTCCCTCGCCCGCCATACTCGCCGAGCACAAGCTGCAGCACAGCAAGGTGGGCCAGTCCGGCAAGTGCGCCCACtgtggccagcagctggagcatgTGGCAGCCTTTCGGGCACATCTCGGCGAGCATGGCAATGACGGGCACCTGCCCATGGCCTGCATCTGTTGCCGGCAAACATTGCACTCGGAATTCGAGCTCAGCTTGCATGCCAAATTCCACACCAAATCgccgggcagcggcagcctcCAGGAGCCGGTCTGTGCTCTGTGTCTGGAACCGTTACCGGGCGCAGCGGGTGAGACGGCCAAGCTGTGCGAGAAATGCTGTCGCAAGCATAATCTCAATGGCAAGCGCAAGGAGTCGACGGCGgcggctcctcctcctcctccccctgCTCCTCCCTCTGCTTCGGCAAGCACTACCTATCTGGAGAATCGCTGTAATCTGTGCAAAATGATACTGCCGCACGCCCAGAAACTGCAGGAGCATCTCGTCGAGCACACCTTTGCCGGCACCGAGCAGCGCGGCTTCAATTGCTACATCTGCTCCGCGGTCTTCACAGCGCCCGCTGGCCTCTTGACCCACATAGCCGAGCATGGTGCGCGACCCTACGACTGCAATTTGTGCCCGGAGAAGTTTTACTTTCGCGCCGAGCTCGAGCATCATCAGCGCGCCCACGAGCTGCGAccgccaccaccagcagcagcagcagcacgtgGAGCACAGCCCAAGCAGGAGGCCCACAGCTCCACGGCCAGCTCACCCCTGGCGCCCAGTCCCAGTCATGTCAAGCAGGAGCTGTACGAGTCGGAAACGGCCAACTCGCCCAATGCTGAGCAGCCCAttcaggaggaggaggaataTATCGAAGTGGAGCAAGTGCCGCAGGAGACGCTGCGCTCCGGCGAGCTGCTCAGCACCGAgcgctccagcagcagcgcctga
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQQHQPQLATAAAAHTLEPSSGSGGGGGEESKANGEAVAAQSELEQQEQEAARPKRPAHLHHHHHHHYHHQQALKIANKLRKINKDAKLAAGGTGPGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLDFPKRSRAHVPTTPTPTPLLRCSYCPKATEFSSLEQLNAHLQSAHEQRDSRSSNATAGGEAGEAAQANGFQLSCEYCTMKFANIAALFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKQDLTSPQAQAAEKPEQELPTDLSSNKRRPMTPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEYERHVVAHFLISSSEFNCSASCGKSYAKAEELQQHLLSEHVLTMLKCALCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRSDTDFHVHVKTRHQLDRGSANGGSVAAAAAAAAAAVSAPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVKDKEPGSNMGSLYVNALLPPLAAAAAAAAAATNNNNNNSNLHIDYNVAFKGLFGGTPSPAQSNSKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAASSQATATASSAGGSSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGHLPMACICCRQTLHSEFELSLHAKFHTKSPGSGSLQEPVCALCLEPLPGAAGETAKLCEKCCRKHNLNGKRKESTAAAPPPPPPAPPSASASTTYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPPPPAAAAARGAQPKQEAHSSTASSPLAPSPSHVKQELYESETANSPNAEQPIQEEEEYIEVEQVPQETLRSGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00506307; iTF_00563363; iTF_00475368; iTF_00534734; iTF_00617104;
80% Identity: -