Basic Information

Insect: Drosophila virilis
Gene Symbol: L
Assembly: GCA_007989325.2
Location: CM017608.2:19384648-19393759[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 9.4e-06 0.00056 19.9 2.9 1 23 167 189 167 189 0.98

2 17 0.32 19 5.6 6.2 1 23 195 217 195 217 0.97

3 17 1.6e-07 9.2e-06 25.5 3.2 1 23 223 245 223 245 0.99

4 17 1.1e-05 0.00068 19.6 0.4 1 23 251 273 251 273 0.99

5 17 0.011 0.65 10.2 0.1 2 23 346 370 345 370 0.92

6 17 0.0007 0.042 14.0 0.2 2 23 398 420 397 420 0.95

7 17 0.025 1.5 9.1 0.7 1 23 491 513 491 513 0.97

8 17 0.0071 0.42 10.8 0.1 2 23 521 542 520 542 0.91

9 17 0.0006 0.036 14.2 0.1 1 23 550 574 550 574 0.94

10 17 6.2 3.7e+02 1.6 1.6 2 23 610 632 609 632 0.94

11 17 0.0023 0.14 12.4 1.1 1 23 687 710 687 710 0.97

12 17 0.0059 0.35 11.1 1.6 2 23 883 905 882 905 0.96

13 17 0.11 6.3 7.1 0.1 1 23 911 933 911 933 0.92

14 17 0.51 30 5.0 0.4 2 23 941 962 940 962 0.93

15 17 0.68 41 4.6 0.5 2 23 1064 1085 1064 1085 0.94

16 17 0.029 1.7 8.9 0.0 1 23 1095 1117 1095 1117 0.96

17 17 0.0002 0.012 15.7 1.2 1 23 1122 1144 1122 1144 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	9.4e-06	0.00056	19.9	2.9	1	23	167	189	167	189	0.98
2	17	0.32	19	5.6	6.2	1	23	195	217	195	217	0.97
3	17	1.6e-07	9.2e-06	25.5	3.2	1	23	223	245	223	245	0.99
4	17	1.1e-05	0.00068	19.6	0.4	1	23	251	273	251	273	0.99
5	17	0.011	0.65	10.2	0.1	2	23	346	370	345	370	0.92
6	17	0.0007	0.042	14.0	0.2	2	23	398	420	397	420	0.95
7	17	0.025	1.5	9.1	0.7	1	23	491	513	491	513	0.97
8	17	0.0071	0.42	10.8	0.1	2	23	521	542	520	542	0.91
9	17	0.0006	0.036	14.2	0.1	1	23	550	574	550	574	0.94
10	17	6.2	3.7e+02	1.6	1.6	2	23	610	632	609	632	0.94
11	17	0.0023	0.14	12.4	1.1	1	23	687	710	687	710	0.97
12	17	0.0059	0.35	11.1	1.6	2	23	883	905	882	905	0.96
13	17	0.11	6.3	7.1	0.1	1	23	911	933	911	933	0.92
14	17	0.51	30	5.0	0.4	2	23	941	962	940	962	0.93
15	17	0.68	41	4.6	0.5	2	23	1064	1085	1064	1085	0.94
16	17	0.029	1.7	8.9	0.0	1	23	1095	1117	1095	1117	0.96
17	17	0.0002	0.012	15.7	1.2	1	23	1122	1144	1122	1144	0.97

Sequence Information

Coding Sequence: ATGATGGCTTTAAAGATGTTGTATCGCGGTCCCAGTTCGCGTTTAgagaatttaattgaaaagatTCAAGCCACCAAGGAGATTACAAATAACGACATGTACAGCACGCACACCTCCTCCAGCTACTCGCCGAGCATCTCGGACGGCACATTGACGCCCAAttcgcagcagcatcagccacAATTGGCGACAGCTGCCGCGGCACACACATTGGAAGCCCCCAGCGGCGAGGAGTCTAAGGCGAATGGCGAAGCTGTTGCCGCACAGTCGGAGCTGGatcagcaggagcaggaggcaGCCAGACCCAAGCGACCTGCACAtttgcatcatcatcatcatcattatcatcatcagcaggcGCTGAAAATTGCGAACAAGCTGCGTAAAATCAATAAGGATGCCAAACTGGCAGCTGGTGGCACAGGACCAGGACACGGAACAGCCGCCAAGTTTGATAAGTTGACAGGCGAGGGCATTAAAAGTCGAGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGTCTCGGCTACTTGAAGCATCACGTGCAGAGTCATGCCGAGCATTTGCCTTTCAAGTGCGAATATTGTGCCAAGCTCTTCAAGCACAAACGCTCCCGAGATCGTCATAAGAAGCTGCATACCAACGAGAGGAACTACAAGTGTCCGCATTGCGAGGCTGCTTTCTCGAGAAGCGATCATTTGAAGATTCACATGAAGACGCACGACATTCAGAAGCCCTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACGGCCGCAGCTTTGACCTCGCACATGCAGAAGCACAAGAAGAATGCCGCCATCCTGGCAGCTGGCGGCAATCCCAATGCCCTCAACTATAGCCCCAGATCGACGGGCTCCGCTTCCATTTCGAGCAATGGCAGCCTGCACAAGCGTCGCTATGCGCTGGCCCTCGCCTCCGACAGCAGTCCCAGTCGCTTGGACTTTCCCAAACGCTCTCGGGCTCATGTTCCGACCACGCCCACGCCGACACCGCTGCTGCGCTGCAGCTACTGCCCGAAGGTGACGGAGTTCAGCAGCCTGGAGCAGCTGAATGCGCATCTGCAGAGCGCACACGAGCAGCGAGAGACGCGCAGCTCGACCGCCACGGCTGGCGTGGAGTCTGGAGAGGCTGTACAGGCGAATGGCTTTCAGCTGAGCTGCGAATACTGCACGATGAAATTTGCGAATATCGCTGCGCTGTTTCAGCACATGCGGGCCACACACTTGGATAGGCTGAGCAGTCCGAACTCCTATTACGAGCACTTCAATCGCCTAGCCACGGCGGGCACATTTAGTCCCAGGCTGGCGCTGGAGCTGCCCAAGATCAAGCAGGATCTGGCCAGTCCACAGCCGCAAGCTGCCGAAAAGCCGGAACAGGAGCTGCCCACAGACCTGAGCAGCAATAAGCGTCGCCCGTTGACGCCGCCGGGCGTCTTCTTTTGCAATCAATGCAATGCCGGCTTGCCGGACTTCGAGAGTTTCCGGAATCATCTGAAGACGCACATAGCCGAGGGCATGCAACTAATCTGTCCACACTGCGGCCTGAGTCTGCCCGAGCAGAGCGAATACGAACGCCACGTGGTTGCCCatttcttgatcagcagctcCGAGTTCAACTGCAGCGCCAGCTGCGGCAAATCCTATGCCAAGGccgaggagctgcagcagcatttgcTCAGCGAACACGTGCTCACGATGCTCAAGTGTGCCCTCTGCTCGGAGCTGTGCGAGAATCGTATGTCCATGCAGCTGCATCTGGCCTGTGCGCACAGCCAGGAGTCGAAGCTGTTGCGGTGCAGCGCCTGCCTGGAGCTCTTTCGCAGCGACACGGACTTCCATGTGCATGTCAAGACGCGTCACCAGCTCGATCGTGGTTCGGCAAATGGtggtgctgccgctgccgccgccgctgctgcggctgccgtCTCCGCGCCCGCCAATCCGCTGCAGTGCATGTTCTGTCGCGCTGTTTGCGGCTCGGAGCTGGAAATGCATTTCCATTTGGCTGCGCATGCGCGACAATTCCGCTGTCCCAGCTGCCCGGAAACGTTCCATGTGGAATTTCTGCTCGATCGCCATATGCAGAGCCAGCATGGCGGCGGCGTCAAGGATAAGGAGCCCGGCTCCAATATGGGCAGCCTCTATGTGAATGCCCTGCTGCCGCccctggcagctgctgccgctgccgccgccgcggcgaccaacaacaacaacaacaacaacaacagcaacctgCACATCGACTACAATGTGGCCTTCAAGGGCCTCTTCGGCGGCACGCCCAGCCCAGCACAGTCGAACAGCAAATTCTATAGTCCACTGCAGGTGGACACCAGCGCGTTGAAGCCACAGCAAACGCCGCATCCGGCACTGATGTACGGCCTGAGCCAGCGCTATCTGATGGAAATGTATGCGGCCAAGGCCACATCGCCGGCAGCCAGTGCACCCGAGCTGCCGGCTGCCAGCAGCCAGGCAACGGCGACAGCGTCCAGTGCAGGCGgtagcagcagctacagctgcGGCATGTGCGAGCGGCAGGATTTGCGCAGCGAGGCGGAGCTGCACTCGCATCGCAAGCTGGCGCACAATCTCAAGACGGGCGTCAGCCTGAGATGCGCCTATTGCTCCGGCAATTACAAGTCGCGCGCCGAGCTGGAGCAGCACATGAAGAGCTGTCACAATTCGAGCGGCAAGCACAAGTGTCTCATCTGCGACGAGATCTTTCCCTCGCCCGCCATACTCGCCGAGCACAAGCTGCAGCACAGCAAGGTGGGCCAGTCCGGCAAGTGTGCCCACTGtggccagcagctggagcaTGTGGCCGCCTTTCGGGCACATCTCGGCGAGCATGGCAATGACGGGCACCTGCCCATGGCCTGCATCTGTTGCCGGCAGACATTGCACTCGGAATTCGAGCTCAGCTTGCATGCCAAATTCCACACCAAATCGCCGGGCAGCGGCAGTCTACAGGAGCCGGTCTGTGCTCTGTGCCTGGAACCGTTGCCGGGCGCAGCGGGTGAGACGGCCAAGCTGTGCGAGAAATGCTGTCGCAAGCATAATCTCAATGGCAAGCGCAAGGAGTCAACGGCGGCAGCACCTCCTGCGCCACCTGCTGCTCCCCCTGCGACGGCAAGCACTGCCTATCTAGAGAATCGCTGTAATCTGTGCAAAATGATACTACCGCACGCCCAGAAACTGCAAGAGCATCTCGTCGAGCACACCTTTGCCGGCACCGAGCAGCGCGGCTTCAATTGCTACATATGCTCCGCGGTCTTTACGGCGCCCGCTGGCCTCTTGACCCACATAGCCGAGCATGGCGCTCGTCCCTATGACTGCAATCTGTGCCCGGAGAAGTTTTACTTTCGCGCCGAACTCGAGCATCATCAACGCGCTCACGAGCTGCGACcgccaccaccagcagcagctcgtgcCGCACAGCCCAAACAGGAGACGCACAGCTCCACGGCCAGCTCACCCCTGGCGCCCAGTCCCAGTCATGTCAAGCAGGAACTGTACGAGTCAGAAACGGCCAACTCGCCCAATGCTGAGCAGCCCATTCAGGAGGAGGAGGAATATATCGAAGTGGAACAAGTGCCGCAGGAGACGCTGCGCTCCGGCGAGCTGCTCAGCACCGAGcgctccagcagcagcgcctga
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSQQHQPQLATAAAAHTLEAPSGEESKANGEAVAAQSELDQQEQEAARPKRPAHLHHHHHHYHHQQALKIANKLRKINKDAKLAAGGTGPGHGTAAKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLDFPKRSRAHVPTTPTPTPLLRCSYCPKVTEFSSLEQLNAHLQSAHEQRETRSSTATAGVESGEAVQANGFQLSCEYCTMKFANIAALFQHMRATHLDRLSSPNSYYEHFNRLATAGTFSPRLALELPKIKQDLASPQPQAAEKPEQELPTDLSSNKRRPLTPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEYERHVVAHFLISSSEFNCSASCGKSYAKAEELQQHLLSEHVLTMLKCALCSELCENRMSMQLHLACAHSQESKLLRCSACLELFRSDTDFHVHVKTRHQLDRGSANGGAAAAAAAAAAAVSAPANPLQCMFCRAVCGSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGGVKDKEPGSNMGSLYVNALLPPLAAAAAAAAAATNNNNNNNNSNLHIDYNVAFKGLFGGTPSPAQSNSKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAASSQATATASSAGGSSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGHLPMACICCRQTLHSEFELSLHAKFHTKSPGSGSLQEPVCALCLEPLPGAAGETAKLCEKCCRKHNLNGKRKESTAAAPPAPPAAPPATASTAYLENRCNLCKMILPHAQKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPAGLLTHIAEHGARPYDCNLCPEKFYFRAELEHHQRAHELRPPPPAAARAAQPKQETHSSTASSPLAPSPSHVKQELYESETANSPNAEQPIQEEEEYIEVEQVPQETLRSGELLSTERSSSSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00526768;
80% Identity: -