Basic Information

Insect: Drosophila kambysellisi
Gene Symbol: zfh1
Assembly: GCA_035042185.1
Location: JAWNLS010000312.1:27212-59816[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0068 0.47 11.1 1.5 2 23 84 106 83 106 0.95

2 9 0.0043 0.3 11.7 1.4 1 23 308 330 308 330 0.97

3 9 2.8e-05 0.002 18.6 2.7 2 23 345 366 344 366 0.97

4 9 4.2e-05 0.0029 18.0 6.4 1 23 375 397 375 397 0.99

5 9 5.4e-05 0.0038 17.7 1.6 1 21 403 423 403 424 0.95

6 9 0.032 2.3 8.9 0.4 2 21 742 761 741 762 0.92

7 9 1.6e-05 0.0011 19.3 0.5 1 23 1103 1125 1103 1125 0.94

8 9 6e-05 0.0042 17.5 7.4 1 23 1131 1153 1131 1153 0.98

9 9 0.003 0.21 12.2 4.3 1 21 1159 1179 1159 1180 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0068	0.47	11.1	1.5	2	23	84	106	83	106	0.95
2	9	0.0043	0.3	11.7	1.4	1	23	308	330	308	330	0.97
3	9	2.8e-05	0.002	18.6	2.7	2	23	345	366	344	366	0.97
4	9	4.2e-05	0.0029	18.0	6.4	1	23	375	397	375	397	0.99
5	9	5.4e-05	0.0038	17.7	1.6	1	21	403	423	403	424	0.95
6	9	0.032	2.3	8.9	0.4	2	21	742	761	741	762	0.92
7	9	1.6e-05	0.0011	19.3	0.5	1	23	1103	1125	1103	1125	0.94
8	9	6e-05	0.0042	17.5	7.4	1	23	1131	1153	1131	1153	0.98
9	9	0.003	0.21	12.2	4.3	1	21	1159	1179	1159	1180	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTGTTTTGGCCAAGAGGATAACATAATAATACAGCAGAGTATGCCATCTTCCACAGCCTTCTCCATGCAGTTTCCCTCTTTGGCGTCCAGTTTACACCatcaccaaacaacaacacacaacaacagccagcaaGGCAATGTGGGCGCAGCCAGTACGGAGCATGTGCCACATGCAACCAGTGCCGCCACAGCGAATGCGGCCGATGAGTGTCTGATCAAATGCCCCCAATGCCACAAGCGCTTCAATGAGTTTCAGTCATTTAGCGAGCACATTGCCAGCGAGCATCCGCTGGACAAGCTGAACTATGAGCAGCCGCATCCAGGCGCAGCTCAGCCCGAAAGCGAGCCCGAGGCGGAgcccgaggaggaggaggaggatgaggaggaggagcacaGCAatctgagcagcagcagccagcaacgcTATGCCAAATCcccaagcaacaaaaaccataacaacaacaacaacaacagcagtcacaacaacaacaacaacaacaataataatagtgaAACGGCAAAGAATCAAAATAAACGCATTTCACATTCACCTGCCTCGTTGGGTTCTCCCGTTGCACCCGCCACGCCCAGTGATCTGTTTGCCCATCTGCCAAACCCTGCCGcccatttgcaatttgtggcagCCGCTGCGATGGCCATGCAATCGGCACGCTCAGCCAACTCAcccaacaaccaacagcaacagttgcaacaacagcagcaacatcaacaacaacaacagcagcatcaacaacaacagttgcaacagaagccgagcagcaacagcagcagcattggcaGCAATTCCGCCTATGATCTGGACTTGAGTGCCCATCGTTCCACCTCGAGTCCGGGCTCCACGGCTGGTGGAGATCTCCCTGCTGCCGGCTTCCCCTGCATGCAGTGCACAGCCACCTTCCACAGTCGCGAGCAACTCGAGCAACATCAGCTGCTGCACTCGCCGACGAGGCAGCACACAATCGCACAGAATGTCAAACAGACCTGCAAAATATGCCACAAAACATTCGCGAATGTTTATCGCCTGCAGCGGCACATGATTAGCCACGATGAGTCCGCGCTGCTGcgcaaattcaaatgcaatcaGTGCGAGAAGGCGTTCAAGTTCAAGCATCACCTGAAGGAGCACGTGCGCATCCATTCCGGCGAGAAGCCCTTCAGCTGCGACAACTGCGGCAAGCGATTCTCGCACTCGGGCAGCTTCTCCTCGCACATGACCTCCAAGAAGTGCATCAGCATGTGCCTGAAACTGAACAACAATCGCCAGCTTCTCAAAACGCTGGACAAGAATGCGGAGCAACTGCCTCCCGTAAAGCGTTCGGCCTGCAAGCAATTGGTGGAACCAGTGCTGCCCAATCTGCCCAATCTGCCCATGAATTACTTTGCTGGGGATTCACAGACGTCACCTGTTGGCGTTGGagttgctggcgctgctgcagctgctgctcctccacctcctTCCTTTTATTCCAATTACAGCGCAATGAATGCGGCTTTGTTGGCATTTCCCAATGCTTTTATGGCGGCTGCTTTAGATCCACGCATGCATCCTTATAGCATACAGAGATTGCTGGAGCTAACAGCAGcaggacaacagcagcagcagcagagggagcaggaggagcagcacagagagcagcaggagctgaagagggagcaggagcaggaacgGGAACAGGAGTTGGAAagggagcaggagctggaaagggagcaggagctggaaagggagcagcagctgcaaagagagcagcaggagcagcagcgggagAGAGAACATGAGAGGGAGCAGGCGCAGCGTGAGCAGTTGCAGCGTGAGCAGTTGCAGCGGGAGCAATTGCAGCGGGAGCAGTTGCAGCGGCTGCCCAGCAAACAGGAGGATTATGCAGAGGAGCCAAAGCTTGTCATGGATCTGGAACAGGATGCAGAGCACCTGAatagcgcagcagcagcaaaagcagaaacTAAGACAGCTGTCAAAATGGAGATCAGTCGCGAGACAACGCCACAGCCCGCAGATGCACTCAAAGCCAtcaagcaggagcaggaacaggaacaggagcaggaggagcaaaTGGAGCTGGACATACATATGGAACTGGAGAAGGAACAGctgcaggaactgcagcagcagcaatcctCCCCGGTGGCAATGCCACAGTCAAGCCCGGAACTGCGCTGCAGTCGCTGTGCCAAACAATTTAATCATCCCACCGAGCTGGTGCAGCACGAGAAAGTGCTCTGTGGCCTGATCAAGCaggagctgcaacagcaacactatcatcaacagcagcaacagcaactccagcaacagcagcagcagctgcagcaaactCCGCGCTCTCTTTCCGAtttcgacgacgacgaggatgtGGAGGAGCTGCTGGAGGAGCCACGGCATGCAGACTACGCCGCCGGCAGCAGTGATAGCAATGAGCGCAAGGTGCGCGTTCGCACCGCCATCaacgaggagcagcagcagcagctcaagcaGCACTATGCGCACAATCCGCGACCAAGTCGCGATGAGTTCCGCCGGATTGCAGCGCATCTCCAACTGGATGCACGCGTTGTCCAGGTGTGGTTTCAAAACAATCGCTCGCGGGAGCGCAAGCTGCAGAGCTACACGAGTGGCGGGGCTGGCAACACAACTGAGACAGCAATTCTTGCCAGCTCTGCTGCACTGCCTCCCACACGTGGCGAGGATCAACCTTTGGATTTGTCGCTCAAGCGGGATGCAACGCCGCCTCAgtcgcagctgcagctgccacccGATTACAACGAGACCAGCATGGCCATCAATCTGAGTCGCCGCCAATTGTCCAGCTCGACGGCGTCTGCCATGTCGCCTGCTTCCcttgcggcggcggcggcggcaactcTCTACTTTGCACCACCCTCACCGACGGCGGGCCAGTTGCACAGCGCCACGCCCCCTTTGGCAGCACAGCGTGGCACGCCCTTTGCCGGGCTGCCGCCCTTTCCCATGATGGCCCGCCTGCCGATGGAGGCACTCTTCCAGATGCGTCCGGGCGGGGAATATGCACCGAATCCTCTGATGAACAGTATTAAATTGCCGGACTATCATCGCGGCACCAGCCTCAGCCCCGGTGGCTCCGAGAAGCGTTCGTGGCGCGACGACGACTCGCGCATCTCCCACGAGGACGACTATGTCCTGGCCACGGGCGGTCTGCTGGCGCCCAAGCCGAGGCGCGCCAAGGCCGAGACTCACGGACATGCCGGCGATCCCGATCTGCCCTTTGTGTGTGACCAGTGCGACAAGGCGTTCGCCAAACAGAGCTCCTTGGCCAGGCACAAATACGAGCATTCCGgtCAGCGACCTTATCAGTGCATGGACTGCCCGAAGGCGTTCAAGCACAAGCACCATTTGACGGAGCACAAGCGATTGCATTCCGGCGAGAAGCCGTTTCAGTGTTCCAAGTGCCTGAAGCGGTTCTCCCATTCGGGCAGCTACAGTCAGCACATGAACCACCGCTACTCCTACTGCAAGCCCTACAGGGAATAG
Protein Sequence: MLSCLAPSSTRCFGQEDNIIIQQSMPSSTAFSMQFPSLASSLHHHQTTTHNNSQQGNVGAASTEHVPHATSAATANAADECLIKCPQCHKRFNEFQSFSEHIASEHPLDKLNYEQPHPGAAQPESEPEAEPEEEEEDEEEEHSNLSSSSQQRYAKSPSNKNHNNNNNNSSHNNNNNNNNNSETAKNQNKRISHSPASLGSPVAPATPSDLFAHLPNPAAHLQFVAAAAMAMQSARSANSPNNQQQQLQQQQQHQQQQQQHQQQQLQQKPSSNSSSIGSNSAYDLDLSAHRSTSSPGSTAGGDLPAAGFPCMQCTATFHSREQLEQHQLLHSPTRQHTIAQNVKQTCKICHKTFANVYRLQRHMISHDESALLRKFKCNQCEKAFKFKHHLKEHVRIHSGEKPFSCDNCGKRFSHSGSFSSHMTSKKCISMCLKLNNNRQLLKTLDKNAEQLPPVKRSACKQLVEPVLPNLPNLPMNYFAGDSQTSPVGVGVAGAAAAAAPPPPSFYSNYSAMNAALLAFPNAFMAAALDPRMHPYSIQRLLELTAAGQQQQQQREQEEQHREQQELKREQEQEREQELEREQELEREQELEREQQLQREQQEQQREREHEREQAQREQLQREQLQREQLQREQLQRLPSKQEDYAEEPKLVMDLEQDAEHLNSAAAAKAETKTAVKMEISRETTPQPADALKAIKQEQEQEQEQEEQMELDIHMELEKEQLQELQQQQSSPVAMPQSSPELRCSRCAKQFNHPTELVQHEKVLCGLIKQELQQQHYHQQQQQQLQQQQQQLQQTPRSLSDFDDDEDVEELLEEPRHADYAAGSSDSNERKVRVRTAINEEQQQQLKQHYAHNPRPSRDEFRRIAAHLQLDARVVQVWFQNNRSRERKLQSYTSGGAGNTTETAILASSAALPPTRGEDQPLDLSLKRDATPPQSQLQLPPDYNETSMAINLSRRQLSSSTASAMSPASLAAAAAATLYFAPPSPTAGQLHSATPPLAAQRGTPFAGLPPFPMMARLPMEALFQMRPGGEYAPNPLMNSIKLPDYHRGTSLSPGGSEKRSWRDDDSRISHEDDYVLATGGLLAPKPRRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00497631;
90% Identity: iTF_00522430;
80% Identity: iTF_00525023;