Dinf002785.1
Basic Information
- Insect
- Drosophila infuscata
- Gene Symbol
- zfh1
- Assembly
- GCA_035042205.1
- Location
- JAWNLR010000089.1:720594-751770[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0028 0.2 12.3 1.1 2 23 84 106 83 106 0.95 2 9 0.0044 0.32 11.7 1.4 1 23 310 332 310 332 0.97 3 9 2.9e-05 0.0021 18.5 2.7 2 23 347 368 346 368 0.97 4 9 4.3e-05 0.0031 18.0 6.4 1 23 377 399 377 399 0.99 5 9 5.5e-05 0.004 17.6 1.6 1 21 405 425 405 426 0.95 6 9 0.033 2.4 8.9 0.4 2 21 749 768 748 769 0.92 7 9 1.6e-05 0.0012 19.3 0.5 1 23 1109 1131 1109 1131 0.94 8 9 6.1e-05 0.0044 17.5 7.4 1 23 1137 1159 1137 1159 0.98 9 9 0.003 0.22 12.2 4.3 1 21 1165 1185 1165 1186 0.96
Sequence Information
- Coding Sequence
- ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTGTTTTGGCCAAGAGGATAACATAATAATACAGCAGAGTATGCCATCTTCCACAGCCTTCTCCATGCAGTttCCCTCTTTGGCGTCCAGTTTACACCatcaccaaacaacaacacacaacaacagccagcCAGGAAATGTGGGCGCAGCCAGTACGGAGCATGTGCCACATGCAACCAGTGCCGCCACAGCGAATGCGGCCGATGAGTGTCTGATCAAGTGCCCCCAATGTCACAAGCGCTTCAATGAGTTACAGTCATTTAGCGAGCACATTGCCAGCGAGCATCCGCTGGACAAGCTGAACTATGAGCAGCCGCATCCAGGCGCAGCTCAGCCCGAAAGCGACCCCGAAGCGGAGcccgaggaggaggaagaggatgaggaggaggagcacaGCAAcctaagcagcagcagccagcaacgcTATGCCAAATCcccaagcaacaaaaaccataacaacaacaacaacaacagcagtcacaacaacaacaacaacaacaacaacaataataatagtgaAACGGCAAAGAATCAAAATAAACGCATTTCACATTCACCTGCCTCGTTGGGTTCCCCCGTTGCACCCGCCACGCCCAGTGATCTGTTTGCCCATCTGCCAAACCCTGCCgcccatttgcaatttgtggcagCCGCTGCGATGGCCATGCAATCGGCACGCTCAGCCAACTCAcccaacaaccaacagcaacagttgcaacaacagcagcaacaacaacaacaacagcagcagcagcagcaacaacagttgcaacagaagccgagcagcaacagcagcagcattggcaGCAATTCCGCCTATGATCTGGACTTGAGTGCCCATCGTTCCACCTCGAGTCCGGGCTCCACGGCTGGTGGAGATCTCCCTGCTGCCGGCTTCCCCTGCATGCAGTGCACAGCCACCTTCCACAGTCGCGAGCAACTCGAGCAACATCAGCTGCTGCACTCGCCGACGAGGCAGCACACAATCGCACAGAATGTCAAACAGACCTGCAAAATATGCCACAAAACATTCGCGAATGTTTATCGCCTGCAGCGGCACATGATTAGCCACGATGAGTCGGCGCTGCTGcgcaaattcaaatgcaatcaGTGCGAGAAGGCGTTCAAGTTCAAGCATCACCTGAAGGAGCACGTGCGCATCCATTCCGGCGAGAAGCCCTTCAGCTGCGACAACTGCGGCAAGCGATTCTCGCACTCGGGCAGCTTCTCCTCGCACATGACCTCCAAGAAGTGCATCAGCATGTGCCTGAAACTGAACAACAATCGCCAGCTTCTCAAAACGCTGGACAAGAATGCGGAGCAACTGCCTCCCGTAAAGCGTTCGGCCTGCAAGCAATTGGTGGAACCAGTGCTGCCCAATCTGCCCATGAATTATTTTGCTGGGGATTCACAGACGTCACCTGTTGGCGTTGGagttgctggcgctgctgcagctgctgctcctccacctccttccttttattcaaattacagCGCAATGAATGCGGCTTTGTTGGCATTTCCCAATGCTTTTATGGCGGCTGCTTTAGATCCACGCATGCATCCTTATAGCATACAGAGATTGCTGGAGCTAACAGCAGcaggacaacagcagcagcagagggagcaggaggagcagcatagagagcagcaggagctgaagagggagcaggagcaggagcaggaacgGGAGCAGGAGTTGGAAAGGGAGCAGGAGCTAGAGagggagcagcagctgcaaacagagcagcaggagcagcagcgggaGAGAGAACATGAGAGGGAGCAGGCGCAGCGTGAGCAGTTGCAGCGGGAGCAGTTGCAGCGGGAGCAGTTGCAGCGGGAGCAGTTGCAGCGGGAGCAGTTGCAGCGGGAGCAATTGCAGCGAGAGCAGTTGCAGCGGCTGCCCAGCAAACAGGAGGATTATGCAGAGGAGCCAAAGCTTGTCATGGATCTGGAACAGGATGCAGAGCACCTGAatagcgcagcagcagcaatagcagaaaCTAAGACAGCTGTCAAAATGGAGATCAGTCGCGAGACAACGCCACAGCCCGCAGATGCACTCAAAGCCAtcaagcaggagcaggaacaggagcaggaggagcaaaTGGAGCTGGATATACATATGGATCTGGAGAAggaacagctgcagcaactgcagcagcagcaatcctCCCCGGTGGCAATGCCACAGTCAAGCCCGGAACTGCGCTGCAGTCGCTGTGCCAAACAATTTAATCATCCCACCGAGCTGGTGCAGCACGAGAAAGTGCTCTGTGGCCTGATCAAGCaggagctgcaacagcaacactatcatcaacagcagcaacagcaactccagcaacagcagcagctgcagcaaactCCGCGCTCTCTTTCCGAtttcgacgacgacgaggatgtGGAGGAGCTGCTGGAGGAGCCACGGCATGCAGACTACGCCGCCGGCAGCAGTGATAGCAATGAGCGCAAGGTGCGCGTTCGCACCGCCATCaacgaggagcagcagcagcagctcaagcAGCACTATGCGCACAATCCGCGACCAAGTCGCGATGAGTTCCGCCGAATTGCAGCGCATCTCCAACTGGATGCACGCGTTGTCCAGGTGTGGTTTCAAAACAATCGCTCGCGGGAGCGCAAGCTGCAGAGCTACACGAGTGGCGGGGCTGGCAACACAACTGAGACAGCAATCCTTGCCAGCTCTGCTGCACTGCCTCCCACACGTGGCGAGGATCAACCTTTGGATTTGTCGCTCAAGCGGGATGCAACGCCGCCTCAgtcgcagctgcagctgccatcCGATTACAACGAGACCAGCATGGCCATCAATctgagtcgccgccaattgTCCAGCTCGGCGGCGTCTGCCATGTCGCCTGCTTCCcttgcggcggcggcggcggcaactCTCTACTTTGCACCACCCTCACCGACAGCAGGCCCGTTGCACAGCGCCACGCCCCCTTTGGCAGCACAGCGTGGCACGCCCTTTGCCGGGCTGCCGCCCTTTCCCATGATGGCCCGCCTGCCGATGGAGGCACTCTTCCAGATGCGTCCGGGCGGGGAGTATGCACCGAATCCTTTGATGAACAGTATTAAATTGCCGGACTATCATCGCGGCACCAGCCTCAGCCCCGGTGGCTCCGAGAAGCGTTCGTGGCGCGACGACGACTCGCGCATCTCCCACGAGGACGACTATGTCCTGGCCACGGGCGGTCTGCTGGCGCCCAAACCGAGGCGCGCCAAGGCCGAGACTCACGGACATGCCGGCGATCCCGATCTGCCCTTTGTGTGTGACCAGTGCGACAAGGCGTTCGCCAAACAGAGCTCCTTGGCCAGGCACAAATACGAGCATTCCGgtCAGCGACCTTATCAGTGCATGGACTGCCCGAAGGCGTTCAAGCACAAGCACCATTTGACGGAGCACAAGCGATTGCATTCCGGCGAGAAGCCGTTCCAGTGTTCCAAGTGCCTGAAGCGGTTCTCCCATTCGGGCAGCTACAGTCAGCACATGAACCACCGCTACTCCTACTGCAAGCCCTACAGGGAATAG
- Protein Sequence
- MLSCLAPSSTRCFGQEDNIIIQQSMPSSTAFSMQFPSLASSLHHHQTTTHNNSQPGNVGAASTEHVPHATSAATANAADECLIKCPQCHKRFNELQSFSEHIASEHPLDKLNYEQPHPGAAQPESDPEAEPEEEEEDEEEEHSNLSSSSQQRYAKSPSNKNHNNNNNNSSHNNNNNNNNNNNSETAKNQNKRISHSPASLGSPVAPATPSDLFAHLPNPAAHLQFVAAAAMAMQSARSANSPNNQQQQLQQQQQQQQQQQQQQQQQLQQKPSSNSSSIGSNSAYDLDLSAHRSTSSPGSTAGGDLPAAGFPCMQCTATFHSREQLEQHQLLHSPTRQHTIAQNVKQTCKICHKTFANVYRLQRHMISHDESALLRKFKCNQCEKAFKFKHHLKEHVRIHSGEKPFSCDNCGKRFSHSGSFSSHMTSKKCISMCLKLNNNRQLLKTLDKNAEQLPPVKRSACKQLVEPVLPNLPMNYFAGDSQTSPVGVGVAGAAAAAAPPPPSFYSNYSAMNAALLAFPNAFMAAALDPRMHPYSIQRLLELTAAGQQQQQREQEEQHREQQELKREQEQEQEREQELEREQELEREQQLQTEQQEQQREREHEREQAQREQLQREQLQREQLQREQLQREQLQREQLQREQLQRLPSKQEDYAEEPKLVMDLEQDAEHLNSAAAAIAETKTAVKMEISRETTPQPADALKAIKQEQEQEQEEQMELDIHMDLEKEQLQQLQQQQSSPVAMPQSSPELRCSRCAKQFNHPTELVQHEKVLCGLIKQELQQQHYHQQQQQQLQQQQQLQQTPRSLSDFDDDEDVEELLEEPRHADYAAGSSDSNERKVRVRTAINEEQQQQLKQHYAHNPRPSRDEFRRIAAHLQLDARVVQVWFQNNRSRERKLQSYTSGGAGNTTETAILASSAALPPTRGEDQPLDLSLKRDATPPQSQLQLPSDYNETSMAINLSRRQLSSSAASAMSPASLAAAAAATLYFAPPSPTAGPLHSATPPLAAQRGTPFAGLPPFPMMARLPMEALFQMRPGGEYAPNPLMNSIKLPDYHRGTSLSPGGSEKRSWRDDDSRISHEDDYVLATGGLLAPKPRRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00497631;
- 90% Identity
- iTF_00522064; iTF_00548701; iTF_00549045; iTF_00525376; iTF_00525023;
- 80% Identity
- iTF_00522064;