Basic Information

Insect: Drosophila infuscata
Gene Symbol: zfh1
Assembly: GCA_035042205.1
Location: JAWNLR010000999.1:429928-435112[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.9e-05 0.0021 18.5 1.0 1 23 152 174 152 174 0.97

2 15 0.0009 0.065 13.8 1.2 3 23 182 202 180 202 0.94

3 15 9.8e-05 0.0071 16.9 0.1 1 23 379 401 379 401 0.98

4 15 0.00034 0.024 15.2 0.9 1 23 407 429 407 429 0.98

5 15 0.00012 0.0087 16.6 2.3 1 23 461 484 461 484 0.94

6 15 0.012 0.86 10.3 3.0 1 23 529 551 529 551 0.94

7 15 0.003 0.22 12.2 0.3 1 23 557 580 557 580 0.98

8 15 0.029 2.1 9.1 0.4 3 19 589 605 588 606 0.95

9 15 0.00017 0.012 16.1 5.6 1 23 615 637 615 637 0.97

10 15 0.044 3.2 8.5 1.2 2 23 643 664 642 664 0.96

11 15 1e-05 0.00072 20.0 1.0 1 23 673 695 673 695 0.98

12 15 0.0011 0.082 13.5 0.1 3 23 703 723 701 723 0.97

13 15 6.1e-05 0.0044 17.5 0.5 1 23 729 751 729 752 0.95

14 15 0.051 3.7 8.3 0.4 1 23 762 784 762 784 0.97

15 15 0.0027 0.19 12.4 0.4 1 23 1300 1322 1300 1322 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.9e-05	0.0021	18.5	1.0	1	23	152	174	152	174	0.97
2	15	0.0009	0.065	13.8	1.2	3	23	182	202	180	202	0.94
3	15	9.8e-05	0.0071	16.9	0.1	1	23	379	401	379	401	0.98
4	15	0.00034	0.024	15.2	0.9	1	23	407	429	407	429	0.98
5	15	0.00012	0.0087	16.6	2.3	1	23	461	484	461	484	0.94
6	15	0.012	0.86	10.3	3.0	1	23	529	551	529	551	0.94
7	15	0.003	0.22	12.2	0.3	1	23	557	580	557	580	0.98
8	15	0.029	2.1	9.1	0.4	3	19	589	605	588	606	0.95
9	15	0.00017	0.012	16.1	5.6	1	23	615	637	615	637	0.97
10	15	0.044	3.2	8.5	1.2	2	23	643	664	642	664	0.96
11	15	1e-05	0.00072	20.0	1.0	1	23	673	695	673	695	0.98
12	15	0.0011	0.082	13.5	0.1	3	23	703	723	701	723	0.97
13	15	6.1e-05	0.0044	17.5	0.5	1	23	729	751	729	752	0.95
14	15	0.051	3.7	8.3	0.4	1	23	762	784	762	784	0.97
15	15	0.0027	0.19	12.4	0.4	1	23	1300	1322	1300	1322	0.97

Sequence Information

Coding Sequence: ATGAACAATCCGGACTATGGCGGCATCCAGTGGATACAGCATGAAAGCAGCGCCGTCGTCGACGACAGCGAAACAGAGATGACACCAGACTATTTGGTCAACGCTGCCGCAAATGGAAGCATTTCCAACGATGACGATCTCGATCATATGGCAGCCGAGAATCTCATCTTTATGGCACGCGACGGCCAACTGAGCGAAATCATCGCCGCAAATGAGGCAaatggcggcagcagcacagTGCTAATCGCGGAGAGCGACGATAATAACGGTGTGGAATACGCCGAGTCCTTTGACGATGATGCTCAGGTCGTCACCGAGGAGATTATCACAGATGATTGGGTCCAGCATCAGGGCGCAGAGCGtgTGGAAATTGCCGCTGAGCAAATCGCTGGCAATGGCAGCTCCCAGGAGCTGTTGGACATGCAACAGAATGAATATATGGCGATGCGCCCATATCCCTGCGACTTTTGCAGTCGACGCTTTCGCAAGAAGGCCAGCCTCAACAATCATATGCTTGCGCATCAGAATGATCGTCCGCATCTTTGCAAGCTGTGTGGGGCGCGTTTCTCGCGTCGCGCGGAGCTCATCAGTCACTTCAAGGCGCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATTAAATTTgagccacaacagcagctgcaacagcagcagcagcaacagcgacaaatCGAGGATCATTTCTATGAGCATGAATGGCCGCTGTATCAGGAACAAGAGCAGGCGCAGGAGCTGGAACAGGTCgaggagcagctggagcagatcgagaaacagcaacagcagcaactggagcatcatcagcagctgttgcaacaaTCGGTTGCACCACCAACTGCTGCCCGAGGACGCATCAGTCGCTTAAAGCTCAAGGAGGAGAGCTCGCAATACATTGTGATTGCCTCCGATAATCCGGAGACGGAATTGCCTCAATACATGCATAGCGAGGCTAATTGCGATCAATCACttgccaccaacaacaaccaactcCAATCAACATCATCCGAtgatgctgcaactgctgctgctgctgctgctgctaccgaTGGGTCACAGGGGCACGCAACACTGCGCTTTCCCGTGCTCGACGAGAGCAAACCCTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCGCTCGTCTCCCACATCAAGAATCATCGTGTGGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAATTACAGTCTGCAGGAGCATCAGAAGACGCATCAGTTTGAGGAGAGCAATTCGGAATACGATCCGGCATCGGCGGGCGACGAGGATACGGCGAGTGAATCGGAAGCGGATCAGCTTTACGGTGTTTTCTACTGCGGCGAATGCGGCATCTCCTTTCACCGGCAGGATTTGTTGCGGCgccacagcaaacagcagcacagCAAGCAGCTGGCTGCAGCAACGActggtggcaacaacaacagtgtggcaactgcaacagcaacggatGCAGTaggtgctgcagctgcaactgatgccgatgccgatgctgaTGATGCCAAAGATGCGCCACATTGTTGCCACACGTGCGGCAAATCATTTCCCAGCGTACTCAAACTGCTCGCCCATGCCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTCCTGTGCGGAGTCAGCTTCTACGATGAGCTGGCGATAAAGCGGCACCTGAACACGCGGCATCCGCACGAGTTGAAGCCCAAttcgtgtgtgttgtgtggcaAGGAGTGTCGCGATCGGAAGGCGCTGATCAAACATGCGTGGGATCATTCGCGGGAGAAGTGCCACTCGTGCTCAAAGTGTGGCAAGAATTTCCACAACAAGGCGCGCCTGAAGCGACACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTTTGCCACGAGGAGTTCCCCGATGGACGCACCTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAACTGTTCCCATGCCACGAGTGTGGCAAGACTTTTGGGTCTCGCAGCTCGCAGCAGATTCATGTGCGCATCCACACGGGCGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGATGGCGGCACTCTCCGCAAACACGAACGCATCCACACGGGCGAGAAGCCCTATGCCTGCTCCGTCTGTCCGCGTGCTTTCAACCAGCGTGTCGTCTTGCGGGAACACATCCGCTCGCATCACTCCGGTCTGGATGCGGTACGTGGCACGTACCATTGCACGGTCTGCTCCGCGGATTTGAGCTCATCGAATGACCTCATCCAGCACCTCATCCAGCACAGTGATACGAATACAGCCAAACAGCGACAGCCAATTaCTGGTCCACGTAAATACAAACGACGCCGGAAACTGCAGCCGCATGAGATTGCGCACATGCGTGCCGAGCACAAGGCTGGTGGCGTCGGCGATGGCGAGGCTGGCGAGGAGGAGGATTATGGCAGCGACTTGGACTACTGCGATTTGGATGTGGAGAATGTGGATGAGTTGCTGCAGGAGGCAACCGCAGAGCCGCCACCACCCACCAAAAAAGCGAAACGCAAACGCAAAGCGCCAACTAAAAGCGGCGATGAGCAAAGATTGTGGGACGAGAAATTACTGCAGCAGGCGAACAATGGGAATAGCGATGAGGCGTACAAGAGTTTCTTTCAAATGGACTCGCTGGTCGTGGTCAATGATCAAACGCTGCAACCCGTTGATGCTGGTGTTGCCGCGACCAAGTTGCAGCAGTCGGAGATTAAGGAGCAAACGCTGAAGACAGGCAatcgcagcagcaaaagaaggGCAGGCAAAGTTAGCGCAGGAGGAGCAGCCGGAGGAGGAACAGCAGGCGGAGGAGCATCAGGaggaactgctgctgctccacgtCCCCGTATGATACACACGGCCAAGTCGCAGCAGACAACGTCAAGGAAGTCCCGCACAAGGAGTTATGTCACACGCACCAGCACCAATGAGAAGCAGCAGGGGGAAGGAGCAAGTGGAGGAAGTCTTATCAAATCACGCATTGTGGATGACTACGAGATCATCTCACCGGCCACACAGCCACCCAATCAGATCAGTTCCAGTCCGCTGCACATCaaacaggagcaggaacatcaacagcatcatcatcatcatcatcaacagcagcagcagcatcagcagcagcagcgagtccAACTGCTCTTCGATGACAGCCATCTGCTCATTGAATCGGGCCTATTGCGTGAAAAGACCTACGAGAAATATAATCCCAGCATTGTTCAAGATCTCGAGGAGATTTTGCGTAGTCCCCCGAAGCATGAGCGGAACGATCGACGGCTGCGCTTCACCAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGAGAGGAGGAGGAACAGCATCTCATCAAGATCGAGCCCACATCGCCGGATCTCCGGGAAATGGTAGAgagccagcagccagccacaCTGCCCACATCCTCCTCCGTCTGTTCAACGGCGGCACGCACTTCCCGCCACCTGCGACAGCTGACTGCCAATGGTCCTCCCAGTTCCATTTCCACTGTCACTTCTAGTTCCAGTGCCGCTTCCAGTACGCGAGCCGCTTCCAAGCGCAATGCCAGCAAACAACTTTCCAAGAAATCCGCTTCCAATAGCAACAAGGGCAACTCCTCAACGTCTTATCTCAGCTATGGCGTCGACTCCTataatgtgggcgtggcagccaGTGCCAATAGCTCCTCGGATGTCAGTTCAGGTTTCTTCTCAATTTCCGAGGTCGTCTCGGCGGCGGATGCAGCCGATGCAGCTGcgaaggcggcggcggcagcagcctGCAAAACGGAGCAAAGAACGCGCTGCTATGAGTGTGAAATGTGCTCCTCCAATTTTCCAGATCGTGCCCAGCTGCTGGAACACATGCATGAACACATCTAG
Protein Sequence: MNNPDYGGIQWIQHESSAVVDDSETEMTPDYLVNAAANGSISNDDDLDHMAAENLIFMARDGQLSEIIAANEANGGSSTVLIAESDDNNGVEYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADEEAAAAAIKFEPQQQLQQQQQQQRQIEDHFYEHEWPLYQEQEQAQELEQVEEQLEQIEKQQQQQLEHHQQLLQQSVAPPTAARGRISRLKLKEESSQYIVIASDNPETELPQYMHSEANCDQSLATNNNQLQSTSSDDAATAAAAAAATDGSQGHATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGDEDTASESEADQLYGVFYCGECGISFHRQDLLRRHSKQQHSKQLAAATTGGNNNSVATATATDAVGAAAATDADADADDAKDAPHCCHTCGKSFPSVLKLLAHAEIHKRFPPFKCVLCGVSFYDELAIKRHLNTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGVGDGEAGEEEDYGSDLDYCDLDVENVDELLQEATAEPPPPTKKAKRKRKAPTKSGDEQRLWDEKLLQQANNGNSDEAYKSFFQMDSLVVVNDQTLQPVDAGVAATKLQQSEIKEQTLKTGNRSSKRRAGKVSAGGAAGGGTAGGGASGGTAAAPRPRMIHTAKSQQTTSRKSRTRSYVTRTSTNEKQQGEGASGGSLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHHHHHQQQQQHQQQQRVQLLFDDSHLLIESGLLREKTYEKYNPSIVQDLEEILRSPPKHERNDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPATLPTSSSVCSTAARTSRHLRQLTANGPPSSISTVTSSSSAASSTRAASKRNASKQLSKKSASNSNKGNSSTSYLSYGVDSYNVGVAASANSSSDVSSGFFSISEVVSAADAADAAAKAAAAAACKTEQRTRCYECEMCSSNFPDRAQLLEHMHEHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: iTF_00499722;
80% Identity: -