Dgua009783.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila guanche
Gene Symbol
ftz-f1
Assembly
GCA_900245975.1
Location
NW:2223786-2274365[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2 1.3e+04 -23.0 26.0 62 62 220 220 8 367 0.56
2 3 1.7e-19 1.1e-15 57.6 0.3 1 76 565 639 565 668 0.79
3 3 1.9e-70 1.2e-66 225.4 2.5 157 408 770 1014 754 1016 0.92

Sequence Information

Coding Sequence
ATGGACACCTTCAATGTACCTTTGCTGGCGGagagcgccagcagcagcagcaattatgCGGTAGCAGCAGTCACAGaggcaacaaacagcaacaaccatcatcatcatctgcagcaccagcaaaatCTTATGGCCCATCATCACAAGGATCAGATGCTGGCGGCGGGAAGTAGTCCCATGCTGCCATTCCTCAGTTActctcagctgcagctgcagcagaaggatACTACtgctaccagcagcagcaatggtgCACAATCcgaaggagcagaagcagcagcagcagccatttcCACAGATAATTTTGATGGCAGCCAATTGGATGGTGGCATCTCTCTTAGCGGCCTCTGCGAACGCTTCTTTGTAGCCAGTCCCAATTCTCATAGCAATAGCAACATGACCCTAATGGGCGCCCCCAATCCAACAAATACAACAGCTAGCCAGAACAACActatcatcaacaacaacaacaatttggagGCTAAAAACGGGACCAGCCACACAGGTGCGGGAGCTCCCCAATCGCTGCAGAGAGGCGGAGGATCAGTTATCATCGAATCGGTGACCGTACCTTCTTTTTCCAACATCCTCTTCTCCCATCGAAATTCTCAAGCCACATCGAATGAATGCATCGATCCGGCACTGCTGCAGAAGTCCTCACTATCCAGCAGCTCCATTATAGAGTACCATCAGCTGAAACCCCTGGCACCGAGTGCCACCAACTCGGCGTCCGTTTCCACCAGCAATTTCCTGTCCTCGAGCACCGCTCAGCTGTTGGATTTTGATGTGCAAGGCACTTCCAAGGATGAAAGCCATATAAGtaccaccacaaccacagctGGAGTGGGAGTAGGTGCACGATCGGGTTCGAGTTCAGGATCCGCATCGGGTGtagcaacgacaacaacaatcagTGCCAATCAGACAAGAAGCTCACTGCACAGCATCGAGGAATTAGCTGCCAGCTCCTGTGTTGCACCCAAAACCACCCAATCACCcaatgggaatgagaatgagatCCATAGGACTACCACTAGTACAACGCatcagcaggaacagcagcagcagcatcccataCAACAAAGTGGCAATCACAGTGGATCCAATCTCAGCTCTGATGATGAGTCCGTTTCAGAGGATGAGTTCGGTCTGGAAATCGATGATCACGGAGGCTACCAGGACACCACCTCCTCCCACTCACAGCAGAGTGGCGGTGggggcggaggcggtggcggagcTGGCAGCAACATCCTCAACGGCAGCTCGGGCAGCAGCTCCGGCTacatgctgctgccccaagcggccagctccagcggcaACACCAATGCCGCCCACATGTCCTCCGCCGGCGGATCCGTTGGCACTGCCAGCGGCCCCAACGGTGGCGGAGGCGGTTCCGGCCCGGGCAATGCAATGGGCGGTACGAGCGCCACACCGGGACACGGCGGGGAAGTGATCGACTTCAAGCATCTCTTCGAAGAGCTGTGTCCCGTATGCGGCGACAAGGTCAGTGGCTACCACTACGGCCTGCTCACCTGCGAGTCTTGCAAGGGCTTCTTCAAGCGGACTGTCCAGAACAAGAAGGTCTACACCTGCGTGGCGGAGCGGTCGTGCCACATCGACAAGACGCAGCGCAAGCGGTGTCCCTACTGCCGTTTCCAAAAGTGCCTGGAGGTGGGGATGAAGCTGGAGGCTGTACGAGCGGATCGGATGCGGGGTGGCAGGAACAAGTTCGGACCCATGTACAAGCGAGATCGGGCGCGGAAGCTGCAGGTCATGCGACAACGGCAGATCGCCCTACAGGCTCTGCGCAACTCGATGGGGCCGGACATCAAGCCGACGCCGATCTCGCCGGGCTACCAAGCATATCCAAATATGAACATTAAGCAGGAAATCCAAATACCTCAGGTATCCTCACTCACGCAATCGCCAGACTCGTCGCCCAgccccattgccattgctctGGGCCAGGTGAATGCCAGCACGGGCGGAGTGATATCCACGCCCCTTAATGCCGGAAACGGGGGCAGTGGCGGTCTGAACGGCCCCAGCTCCGTTGGAAATGGCAatagcagcaacggcagcagcacaggcaacaacaacaccggcagcagcacaggcaaCGGTGCAGGTGGCGCCGGCggaggaggcggtggaggcaacaatgcgggtggcggcggcaatAACAGTTCCACCGACGGCCTGCAtcgcaacggcagcggcaacggcagctgccACGAAGCTGGAATAGGATCTCTGCAGAACTCGGCCGACTCGAAACTGTGcttcGATTCCGGCACTCATCCATCGAGCACAGCCGATGCGCTTATCGAGCCACTGAGAGTCTCCCCGATGATACGAGAATTTGTGCAATCGATTGACGATCGGGAATGGCAGACGCAGCTTTTCgcgctgctgcagaagcagacCTACAACCAGGTGGAGGTGGATCTCTTTGAGCTGATGTGCAAGGTGCTCGATCAGAATCTGTTCTCGCAAGTGGACTGGGCACGGAACACGGTCTTCTTTAAGGACCTGAAGGTCGATGATCAAATGAAGCTGCTGCAACACTCCTGGTCGGACATGCTGGTCCTCGACCACCTGCACCATCGCATCCACAACGGGCTGCCCGATGAGACGCAGCTGAACAATGGACAAGTCTTCAATCTACTCAGTCTGGGGCTGTTGGGCGTGCCGCAATTGTCCGACTATTTCAACGAGCTGCAGAATAAGCTGCAGGACCTGAAATTCGACATGGGCGACTATGTCTGCATGAAATTCCTTATACTTTTGAATCCAACTGTACGAGGCATTGTGAACAGAAAGACCGTGTCAGAGGGACATGATAATGTGCAGGCAGCCCTTCTGGACTACACCCTCACCTGTTATCCTTCAGTCAATGACAAATTCAGTAGGCTAGTGAACATCTTACCGGAAATCCATGCCATGGCCGCACGCGGCGAGGAGCACCTCTACTCCAAACACTGTGATGGCAATGCACCCACCCAGACTCTGCTCATGGAGATGCTGCACGCCAAGCGGAAGGTGTAG
Protein Sequence
MDTFNVPLLAESASSSSNYAVAAVTEATNSNNHHHHLQHQQNLMAHHHKDQMLAAGSSPMLPFLSYSQLQLQQKDTTATSSSNGAQSEGAEAAAAAISTDNFDGSQLDGGISLSGLCERFFVASPNSHSNSNMTLMGAPNPTNTTASQNNTIINNNNNLEAKNGTSHTGAGAPQSLQRGGGSVIIESVTVPSFSNILFSHRNSQATSNECIDPALLQKSSLSSSSIIEYHQLKPLAPSATNSASVSTSNFLSSSTAQLLDFDVQGTSKDESHISTTTTTAGVGVGARSGSSSGSASGVATTTTISANQTRSSLHSIEELAASSCVAPKTTQSPNGNENEIHRTTTSTTHQQEQQQQHPIQQSGNHSGSNLSSDDESVSEDEFGLEIDDHGGYQDTTSSHSQQSGGGGGGGGGAGSNILNGSSGSSSGYMLLPQAASSSGNTNAAHMSSAGGSVGTASGPNGGGGGSGPGNAMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQIALQALRNSMGPDIKPTPISPGYQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVISTPLNAGNGGSGGLNGPSSVGNGNSSNGSSTGNNNTGSSTGNGAGGAGGGGGGGNNAGGGGNNSSTDGLHRNGSGNGSCHEAGIGSLQNSADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLLSLGLLGVPQLSDYFNELQNKLQDLKFDMGDYVCMKFLILLNPTVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFSRLVNILPEIHAMAARGEEHLYSKHCDGNAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00514941;
90% Identity
iTF_00563935;
80% Identity
iTF_00514941;