Dgla013774.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila glabriapex
Gene Symbol
Mtf1
Assembly
GCA_035042305.1
Location
JAWNLN010000071.1:3241341-3249737[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 6 0.00013 0.0084 16.4 1.9 1 23 329 353 329 353 0.99
2 6 0.00027 0.017 15.4 0.4 1 23 359 383 359 383 0.98
3 6 7e-05 0.0044 17.3 0.9 1 23 389 413 389 413 0.98
4 6 1.6e-07 1e-05 25.6 5.1 1 23 418 440 418 440 0.98
5 6 1.2e-06 7.6e-05 22.8 3.2 1 23 446 470 446 470 0.99
6 6 0.00015 0.0092 16.3 3.7 1 23 476 500 476 500 0.95

Sequence Information

Coding Sequence
ATGGATGCAAGCAAcgatcagcaacaacaacaacaacagcagcaacaacaatactatGAGCACAGTTGGAAGTCAGCCAATCATGGAAATTCCTTATCAGACAGCAGGGATTATGATACAAACTCAACGCGCACATCGCTGACTGGTTCGCCGCCGATAACATCATCAACTGGTCTGGACTTTAATGGATTTGAAGACAAAACGCTGCTGGCATCGCTGCTTGCGCCCAAATTAGATGatgccggcagcagcagtagcagcaacagcatttaCACAACTGGGGAGCAACAGGTGCTGCAACCATTAggcttaacaacaacaaacacaactgcgacgacgacaacaacaacaacgacataTACTTTATATGGCCCGGCGGAATTGCAGGCACAGACAGTTATAGCTGACGAGGAcgatgacgctgacgctgacgatgACTTAGTTGAGGACGAATTGGTCACACTGACAAGTGCACCCCTGTTGCTaaccagcaccaacaacaacaaccacaatagcaacaacaacaatatcacatcatccacacacacattatccACACCAATTTCACCATATCATCAAACACAGTCCACACCGATACCTGTAATAGCAACAATGGGCACATACAATCTGGATGATATTTGCTTTACGTTGGAATATCAGTTTCTAAATCAAAAGCTCGTCCAGGTGCAGCCACCCACAGTGGTGTCCTTCAGCATGTTATCgccagaagaagaagatgaacaacaacccacaaaaacaacagcaactagcagcgacaacaacaactcaagtTCTTCTcctaatacaacaacaacaactgcatatTTCACTCTTGGGACGAGCTATATCGAAGAGCAAACAGAGCCCGATGAGGACAATGAGCTGGCTCACTGCATCCATCCGGGCGCCCTGCACAAGGACACCGACGAGGATCAGCTGTTGATGGCGATGGCCTACGAGAGCTCCGATGAAGCTCTCAGCCGTTATAAATGCAACTATGAAAATTGTTATCGCAGCTACAGCACAATTGGAAATCTGCGTACACATTTAAAGACACACACAGgTGATTACAGCTTCAAGTGTACAGAGGAAGGCTGTAACAAGGCATTCCTCACATCATACAGCCTGAAAATCCATGTACGCGTCCACACCAAAATCAAACCCTACGAATGCGAAGTCAGCGGCTGTGATAAAGCCTTCAACACGCGATACAGATTGCACGCCCATCTGCGACTGCACAATGGCGAGACATTCAATTGTGAAATGTGCCAAAAGTGTTTCACGACCCTCAGCGATCTGAAGAAGCATATGCGCACCCACACTCAGGAGCGACCCTACAAGTGTCCCGAGGATGATTGCGGCAAAGCCTTCACCGCATCGCATCATTTGAAAACGCATCGGCGCACGCATACCGGCGAGAAGCCGTATCCTTGTCAGGAGGATAGCTGCCAGAAGTCATTCAGCACATCGCACAGCTTGAAATCGCACAAGAAGACGCATCAGCGCCAGCTGCTCAGCAAGGGgggcaacaaaaagaaatcgaaGCGTGCTCAGAAACTGCTGCAACAGGAACTgcaccagcaacaagagcaTCAGCAGGAGCAAGAGCaactggagcaggagcaactGGAACAGGAGCTGTTGGTGCTGCAAAAGACAGACGACATGGTGCTCTTCAATCCGGGCAGTCAGAGCTCGGAGACAACGAGCAACGATAGCGGCGTTGTAATCCAGCAGTTGGCCAATGTCTGCTTGCTGCCAGAGACATCGCAAGCATATCCTTTGTCCTATGCGGCCGAGGAGGAGATACCCAGTCCGTGGATTGATGCTGGTGTGCTCGTTTCCAAGCCCATTATGCCGATGGCACCGTTGACCGATGCCTGCGTTGCACTCGCCACAGAAATGCCCAGTTTTGTGGATTTGAAACACACATTTGGTAGTGCTGCTATCAGTGGTGGCACCATGGAGGAGCCAACACCACTCGATGTGGAAATGTTGAACAGCACAAATTCAAATCCAACAAATGCAACTGGCAATCTGCCCACACTGGAGCTAAATCCGCAGAACATTGAGGAGCTGCTGCGCGACGATAGTTTTGACAACGATGAAGATATGGAAACCGAATCCCTGTTGAACGACATCCTGATGACCATTGATAATAATAGTGCGCTGCTGCAGGCGACACTCCATCAGGCAGCCCAGGTGCCCAGCAATGCATCGGGTCTGGTGGAGCTGGACATAAGGGACAATAAGCCGACACTTAAACAGATTACAGCAGATGCGGGCATCTGCAATTGCACTAATTGCAAGTGTGATCAGACCAAGAGCTGTCATGGCGGTGACTGTGGTgcaaccaacaaaccaaccaCAATCAGTCACAAacccacaacaaccacaacaattcAAACGGCGAACAGCAGCTCGAGACGCATCTGTGGCAGCGTTGCCAGCAAAAAAGTGAGTAGACGCGATGCGGAAATAAATCAGAACATCGAGGATGTTGCTTTACTGCTCCAGAATTTGGCTTCCATGAGTGGTGCaagcagcagcgctgctggcggtggtggtggttgctgtggtggtggtggtgctgctgctgctcctgctcctcctcttccagttgcagcagctccagcatcGGCTTGTGCTTGCTCCACAGCTGTGTCCAAGCCGACGCCAACTGGAGGCTGTTGTGCTCCACCAGCACCTTCGCCGCccgtcagctgcagctgctgctcctccaacTCTGGAGGCTGCtgcacaccagcaacagcaccgctgccgccgccgcctcctgTTGCCAGCTCCAACTGCTGCTCCATGAAAGCACCGCCGCCGGTAATCCACAGCTCCACGACCGCTCTCAAGGGCAATGCGTGCACGTGCAAGAGTCCGGCGGAGGGCGTCGCCAATGGCTGTTGCGTTGTCATCTGCATGAAAACATTGCAAGCCCTGCGCAAAGTTCTGACACGCCGGAACCTTAACCTAATGCTTTGTCCGCAACAGAACTAA
Protein Sequence
MDASNDQQQQQQQQQQQYYEHSWKSANHGNSLSDSRDYDTNSTRTSLTGSPPITSSTGLDFNGFEDKTLLASLLAPKLDDAGSSSSSNSIYTTGEQQVLQPLGLTTTNTTATTTTTTTTYTLYGPAELQAQTVIADEDDDADADDDLVEDELVTLTSAPLLLTSTNNNNHNSNNNNITSSTHTLSTPISPYHQTQSTPIPVIATMGTYNLDDICFTLEYQFLNQKLVQVQPPTVVSFSMLSPEEEDEQQPTKTTATSSDNNNSSSSPNTTTTTAYFTLGTSYIEEQTEPDEDNELAHCIHPGALHKDTDEDQLLMAMAYESSDEALSRYKCNYENCYRSYSTIGNLRTHLKTHTGDYSFKCTEEGCNKAFLTSYSLKIHVRVHTKIKPYECEVSGCDKAFNTRYRLHAHLRLHNGETFNCEMCQKCFTTLSDLKKHMRTHTQERPYKCPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQLLSKGGNKKKSKRAQKLLQQELHQQQEHQQEQEQLEQEQLEQELLVLQKTDDMVLFNPGSQSSETTSNDSGVVIQQLANVCLLPETSQAYPLSYAAEEEIPSPWIDAGVLVSKPIMPMAPLTDACVALATEMPSFVDLKHTFGSAAISGGTMEEPTPLDVEMLNSTNSNPTNATGNLPTLELNPQNIEELLRDDSFDNDEDMETESLLNDILMTIDNNSALLQATLHQAAQVPSNASGLVELDIRDNKPTLKQITADAGICNCTNCKCDQTKSCHGGDCGATNKPTTISHKPTTTTTIQTANSSSRRICGSVASKKVSRRDAEINQNIEDVALLLQNLASMSGASSSAAGGGGGCCGGGGAAAAPAPPLPVAAAPASACACSTAVSKPTPTGGCCAPPAPSPPVSCSCCSSNSGGCCTPATAPLPPPPPVASSNCCSMKAPPPVIHSSTTALKGNACTCKSPAEGVANGCCVVICMKTLQALRKVLTRRNLNLMLCPQQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00518672;
90% Identity
iTF_00482506;
80% Identity
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