Datr008591.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila atroscutellata
Gene Symbol
Mtf1
Assembly
GCA_035041605.1
Location
JAWNLA010000105.1:1746004-1754566[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 6 0.00014 0.0086 16.4 1.9 1 23 326 350 326 350 0.99
2 6 0.00028 0.018 15.4 0.4 1 23 356 380 356 380 0.98
3 6 7e-05 0.0045 17.3 0.9 1 23 386 410 386 410 0.98
4 6 1.6e-07 1e-05 25.6 5.1 1 23 415 437 415 437 0.98
5 6 1.2e-06 7.8e-05 22.8 3.2 1 23 443 467 443 467 0.99
6 6 0.00015 0.0094 16.3 3.7 1 23 473 497 473 497 0.95

Sequence Information

Coding Sequence
ATGGATGCAAGCAAtgatcatcagcaacaacaacaaccaaatcagcagcaacaacaatactacGAGCACAGTTGGAAGTCAGCCAATCATGGGAATTCCTTATCAGACAGCAGGGATTATGATACAAACTCAACGCGCACATCGCTGACTGGTTCGCCGCCGATAACATCATCAACTGGCCTGGACTTTAATGGATTTGAGGACAAAGCGCTGCTGGCATCGCTGCTTGCGCCCAAATTAGATGataccggcagcagcagtagcagcaacagcatttacACAACTGGGGAGCAACAGGTGCTGCAACCACTAGGCttaacaaccacaacagcgacgacgacagcaaaaacaaaaacaacaacagcgacgtATACTTTATATGGCCCGGCCGAATTGCAGGCTCAGACAGTTATAGCTgacgaggacgatgacgatgacttAGTTGAGGACGAGTTGGTCACACTGACAAGTGCACCCCTGTTGCTaaccagcaccaacaacaacaaccacaatagcaacaacaacaatagcacatcatccacacacacattatccACACCAATTTCACCATATCAAACACAATCCACACCGATACCTGTAATAGCAACAATGGGCACATATAATCTGGACGATATATGCTTTACGTTGGAATATCAGTTTCTAAATCAAAAGCTCGTCCAGGTGCAGCCACCCACAGTGGCGTCCTTCAGCATGTTAccgcaagaagaagaagaacatcctacaaaaacaacagcaactagcagcgacaacaacaactcaagtTCTTCTCCTcctacaagaacaacaactgcataTTTCACTCTTGGGACGAGCTATGTCGAAGAGCAAACAGAGCCCGATGAGGACAATGAGCTGGCTCACTGCATCCATCCGGGCGCCCTGCACAAGGACACCGACGAGGATCAGCTGATGATGGCGATGGCCTACGAGAGCTCCGATGAAGCTCTCAGCCGCTATAAATGCAACTACGAAAACTGTTATCGCAGCTACAGCACAATTGGAAATCTGCGTACACATTTAAAGACACACACAgGTGATTACAGCTTTAAGTGCACGGAGGAAGGCTGTAACAAGGCATTCCTCACATCATACAGCCTGAAAATCCATGTACGCGTGCACACCAAAATCAAACCATACGAATGCGAAGTCAGCGGCTGTGATAAGGCTTTCAACACGCGATACAGATTGCACGCCCATCTGCGACTGCACAATGGCGAGACATTTAATTGCGAAATGTGTCAAAAGTGTTTCACGACACTCAGCGATCTGAAGAAGCATATGCGCACCCACACCCAGGAGCGACCCTACAAGTGTCCTGAGGATGATTGCGGCAAGGCATTCACCGCATCGCATCATTTAAAAACGCATCGGCGCACGCATACAGGCGAGAAACCGTATCCCTGTCAGGAAGATAGCTGTCAGAAGTCTTTCAGCACATCGCACAGCCTGAAATCGCACAAGAAGACACATCAGCGCCAGCTGCTCAGCAAGGGgggcaacaaaaagaaatcaaagcGTGCTCAGAAACTGTTGCACCAGGAACTGCACCACCAGCAGGAGCAAGAACaactggagcaggagcaactgAAACAGGAGCTGTTGGTGCTGCCAAAGACAGACGAGATGGTGCTCTACAATACGGGCAGTCAGAGCTCGGAGACAACCAGCAACGATAGCGGCGTTATCATTCAACAGTTGGCCAATGTTTGCTTACTGTCAGAGACATCACAAGCGTATCCTTTATCCTATGCCGCCGAGGAGGAAATACCCAGTCCATGGATTGATGCTGGTGTGCTCGTTTCCAAGCCCATTATTCCGATGGCACCGTTGACCGATGCCTGCGTTGCACTTGCCACCGAAATGCCCAGTTTTGTGGATTTGAAGCACACATTTGGCAATGCCGCCATCAGTGGTGCCAACATGGAGGAGCCAACACCACTAGATGTGGAAATGTTGAGCAgcacaaattcaaatccaacaaatgcagctgaCAATCTGCCCACGCTGGAGCTGAATCCGCAGAACATTGAGGAGCTGCTGCGTGATGATAGTTTTGACAACGATGAGGATATGGAAACCGAATCCCTGCTCAACGACATCCTGATGACCATTGATAATAACAGTGCTCTGCTGCAGGCGACACTCCATCAGGCAGCCCAGGTGCCCAGTGATGCATCGGGTCTGGTAGAGCTGGACATAAGGGACAATAAGCCGACACTTAAACAGATTACAGCAGATGCGGGCATCTGCAATTGCACCAATTGCAAGTGTGATCAGACCAAAAGCTGTCATGGCGGGGACTGTGGTGCTACCAACAAATCAACCACAACAATCAGCCAcaaacccacaacaacaatacaaacgGCGAACAGCAACTCAAAACGCATCTGTGGCAgcgtggccaacaaaaaagtgaGTAGACACGATGCGGAAATGAATCAGAACATCGAGGATGTTGCTTTACTGCTCCAGAATTTGGCTTCCATGAGTGGCGCAcgcagcagcgctgctggcagcggtggtggttgctgtggtggtggtgctgctgctgctcctcctccagtTGCAGCAACTCCAGCCTCGGCTTGCGTTTGCTCCACATCTGTGCCCAAGCCGGCGCCAACTGGCGGCTGTTGTGCTCCACCAGCACCTCCGCCAcctgtcagcagcagctgctgctccaactCAGGAGGCTGCTgcacaccagcaacaccaccgccgccgccacccgTTGCCAGCTCTAGCTGCTGCTCCATGAAGGCACAGCCAGCACCGCCGCCGCCTGTAATCCACAGCTCCACGAGCGCTCCCAAGGGCAATGCGTGCACTTGCAAGAGTCCGGCGGAGGGCGTCGCCAATGGCTGTTGCATTGTCATCTGCATGAAAACATTGCAAGCCCTGCGCAAAGTTCTGACACGCCGGAACCTCAACCTAATGCTTTGTCCGCAGCAGAATTAA
Protein Sequence
MDASNDHQQQQQPNQQQQQYYEHSWKSANHGNSLSDSRDYDTNSTRTSLTGSPPITSSTGLDFNGFEDKALLASLLAPKLDDTGSSSSSNSIYTTGEQQVLQPLGLTTTTATTTAKTKTTTATYTLYGPAELQAQTVIADEDDDDDLVEDELVTLTSAPLLLTSTNNNNHNSNNNNSTSSTHTLSTPISPYQTQSTPIPVIATMGTYNLDDICFTLEYQFLNQKLVQVQPPTVASFSMLPQEEEEHPTKTTATSSDNNNSSSSPPTRTTTAYFTLGTSYVEEQTEPDEDNELAHCIHPGALHKDTDEDQLMMAMAYESSDEALSRYKCNYENCYRSYSTIGNLRTHLKTHTGDYSFKCTEEGCNKAFLTSYSLKIHVRVHTKIKPYECEVSGCDKAFNTRYRLHAHLRLHNGETFNCEMCQKCFTTLSDLKKHMRTHTQERPYKCPEDDCGKAFTASHHLKTHRRTHTGEKPYPCQEDSCQKSFSTSHSLKSHKKTHQRQLLSKGGNKKKSKRAQKLLHQELHHQQEQEQLEQEQLKQELLVLPKTDEMVLYNTGSQSSETTSNDSGVIIQQLANVCLLSETSQAYPLSYAAEEEIPSPWIDAGVLVSKPIIPMAPLTDACVALATEMPSFVDLKHTFGNAAISGANMEEPTPLDVEMLSSTNSNPTNAADNLPTLELNPQNIEELLRDDSFDNDEDMETESLLNDILMTIDNNSALLQATLHQAAQVPSDASGLVELDIRDNKPTLKQITADAGICNCTNCKCDQTKSCHGGDCGATNKSTTTISHKPTTTIQTANSNSKRICGSVANKKVSRHDAEMNQNIEDVALLLQNLASMSGARSSAAGSGGGCCGGGAAAAPPPVAATPASACVCSTSVPKPAPTGGCCAPPAPPPPVSSSCCSNSGGCCTPATPPPPPPVASSSCCSMKAQPAPPPPVIHSSTSAPKGNACTCKSPAEGVANGCCIVICMKTLQALRKVLTRRNLNLMLCPQQN