Basic Information

Insect: Drosophila fungiperda
Gene Symbol: zfh1
Assembly: GCA_035042345.1
Location: JAWNLM010000165.1:8630971-8663199[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.011 0.74 10.3 0.8 3 23 85 106 83 106 0.94

2 9 0.0029 0.2 12.1 1.4 1 23 296 318 296 318 0.97

3 9 2.5e-05 0.0017 18.6 2.7 2 23 333 354 332 354 0.97

4 9 3.7e-05 0.0026 18.1 6.4 1 23 363 385 363 385 0.99

5 9 4.9e-05 0.0033 17.7 1.6 1 21 391 411 391 412 0.95

6 9 0.029 2 9.0 0.4 2 21 700 719 699 720 0.92

7 9 1.4e-05 0.00098 19.4 0.5 1 23 1062 1084 1062 1084 0.94

8 9 5.3e-05 0.0037 17.6 7.4 1 23 1090 1112 1090 1112 0.98

9 9 0.0027 0.18 12.2 4.3 1 21 1118 1138 1118 1139 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.011	0.74	10.3	0.8	3	23	85	106	83	106	0.94
2	9	0.0029	0.2	12.1	1.4	1	23	296	318	296	318	0.97
3	9	2.5e-05	0.0017	18.6	2.7	2	23	333	354	332	354	0.97
4	9	3.7e-05	0.0026	18.1	6.4	1	23	363	385	363	385	0.99
5	9	4.9e-05	0.0033	17.7	1.6	1	21	391	411	391	412	0.95
6	9	0.029	2	9.0	0.4	2	21	700	719	699	720	0.92
7	9	1.4e-05	0.00098	19.4	0.5	1	23	1062	1084	1062	1084	0.94
8	9	5.3e-05	0.0037	17.6	7.4	1	23	1090	1112	1090	1112	0.98
9	9	0.0027	0.18	12.2	4.3	1	21	1118	1138	1118	1139	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTGTTTTGGCCAAGAGGATAACATAATAATACAGCAGAGTATGCCATCTTCCACAGCCTTCTCCATGCAGTTTCCCTCTTTGGCGTCCAGTTTACACCATCATCaaaccacaacacacaacaacagccagcCAAGCAATGTGGCCGCAGCCAGTACGGAGCATGTGGCACATGCAACCAGTGCTGCCACAGCGAATGCGGGCGATGAGTGCCTGGTCATATGCCCCCAATGCCACAAGCGCTTCAATGAGTTTCAGTCATTTAGCGAGCACATTGCCAGCGAGCATCCGCTGGACAAGCTGAACTATGAGCAGCCGCATCCTGGCGCAGCTCAGCCGGAGAGCGAGcccgaggaggaggatgaggaggaggagcacaGCAatctgagcagcagcagcaatcctCGATATGCCAAATCcccaagcaacaataacaacaataacaacaacagtcacaacaacaataacaataacaataatagtgAAACGGCAAAGAATCAAAATAAACGCATTTCACATTCACCCGCCTCGTTGGGCTCCCCCGTTGCCCCCGCCACGCCCAGCGATCTGTTTGCCCATCTGCCACACCCTGCCGcccatttgcaatttgtggcaGCCGCCGCGATGGCCATGCAATCGGCACGCTCAGCCAACTCACCCAgcaaccaacagcaacagttgcaacaacaacaacagcagcaacaccagcagcagcagcagcaacagttgctacAGAAgccgagcagcaacagcagcagcattggcaGCAATTCCGCCTATGATCTGGATCTGAGCGCCCATCGTTCCACCTCGAGTCCCGGCTCCACAGCTGGCGGAGATCTGCCAGCTGCCGGCTTCCCCTGCATGCAGTGCACAGCCACCTTCCACAATCGCGAGCAACTCGAGCAACATCAGCTGCTCCACTCGCCGACGAGGCAACACACAATCGCACAGAATGTCAAACAGACATGCAAAATCTGTCACAAGACATTCGCGAATGTGTATCGCCTGCAGCGGCACATGATTAGCCATGATGAGTCCGCGCTGCTGCGTAAATTCAAGTGCAACCAGTGCGAGAAGGCGTTCAAGTTCAAGCATCACCTGAAGGAGCACGTGCGCATCCATTCCGGCGAGAAGCCCTTCAGCTGCGACAACTGCGGCAAGCGGTTCTCGCACTCGGGCAGCTTTTCCTCGCACATGACATCCAAGAAGTGCATCAGCATGTGCCTCAAGCTGAACAACAATCGCCAGCTGCTCAAAACGCTGGATAAGAATGCCGAGCAACTGCCTCCGACTAAGCGTTCGGCCTGCAAACAACTGGTGGAACCGGTTCTCCCAAATCTGCCCATGAATTATTTTGCTGGTGATTCACAAACATCTCcggttggagttggagttgctggcggtgctgcagctgctgttcctCCTCCGCCTACCTTTTATTCCAATTATAGCGCAATGAATGCGGCTTTGTTGGCATTTCCCAATGCTTTTATGGCGGCTGCCTTAGATCCACGCATGCATCCCTATAGCATACAGAGATTGCTGGAGTTAACAGCGGcaggacaacagcagcaccagcagcagcagcagagggagcaggaggagcatcacagagagcagcaggagctgaagagggagcaggagcaggagttAGAAagggagcaggagcaggagagggagagggagcagcagctgcagagagaacagcaggagcagcagcgggTGAGGGAGCAGGCGCAGCGCgagcagttgcaattgctgccCAGCAAACAGGAAGATTATGCAGAGGAGCCCAAACTGGTCATGGATCTGGAACAGGATGCAGAGCAtccagtagcagcagcaacagtggaaACCAAGACAGCTGTCAAAATGGAGATCTGTCGCGAGACAACGCCACAGCCCACAGAAGCACTCAAAGCCATCAAGCAGGAACGGGAGcaagagcaggagcaggaacaggagGAGCAAATGGAGCTGGACATGCAAATGGAACTGGAaaaggaacagcagcagcagcagccaccctCCCCTGTGGCCATGCCCCAGTCGAGCCCGGAACTGCGTTGCAGTCGCTGTGCGAAGCAATTTAATCATCCCACCGAGCTGGTGCAGCACGAGAAAGTGCTCTGTGGCCTGATCAAGCaggagctgcaacagcaacactatcaacaacagcaacaacaacagcaactccagcagcagcaacaactgcagcaaactCCTCGTTCCCTTTCCGATTACGATGATGACGAGGATGTGGAGGAGCTGCTGGAGGAGCCACGCCACGCGGACTACGCCGCCGGCAGCAGTGATAGCAATGAGCGCAAGGTGCGCGTTCGCACCGCCATCaacgaggagcagcagcaacagctcaaGCAGCACTATGCCCATAATCCGCGACCAAGTCGCGACGAGTTCCGCCGGATTGCCGCGCATCTCCAGCTGGATGCGCGGGTTGTCCAGGTGTGGTTTCAAAACAATCGCTCGCGGGAGCGCAAGATGCAAAGCTACACAAGTGGCGGCGCTGGCAACACTGAGACAGCCTCGACAATTCTGGCCAGCTCTGCTGCCCTGCCACCCACACGTGGCGAGGATCAGCCGTTGGATTTGTCCCTCAAGCGGGACGCAACGCCGCCGCAGACGCAGCTACAGTTGCCCCCGGATTACAGTGAGGCCAGCATGGCCATCAATCTGAGTCGCCGCCAGTTGTCGGGCTCCGCGGCGTCTGCCATGTCGCCGGCTTCCCTAGCAGCGGCGGCCGCGGCAACTCTTTACTTTGCCCCAACCTCACCGACGGCGGTCCCGTTGCACAACGCCACGCCTCCTTTGGCGGCACAACGGGGCACGCCCTTTGCCGGCCTGCCGCCCTTTCCCATGATGACCCGCCTGCCCATGGAGGCGCTCTTCCAGATGCGTCCCGGCGGCGAATATGCGCCGAATCCTCTGATGAACAGTATTAAATTGCCGGACTATCATCGCGGCACCAGCCTCAGCCCGGGTGGCTCCGAGAAGCGTTCGTGGCGCGACGATGATTCGCGCATCTCCCACGAGGATGACTATGTCCTGGCCACCGGTGGCCTACTGGCCCCCAAGCCGAGGCGTGCCAAGGCCGAGACCCATGGACATGCCGGCGATCCCGATTTGCCCTTTGTGTGTGATCAGTGCGACAAGGCGTTCGCCAAACAGAGCTCCTTGGCCAGGCACAAATATGAGCATTCCGGTCAGCGACCTTATCAGTGCATGGACTGCCCGAAGGCATTCAAGCACAAGCATCACTTGACGGAGCACAAGAGATTGCATTCCGGTGAGAAGCCGTTTCAGTGCTCCAAGTGCTTGAAGCGCTTCTCGCACTCGGGCAGCTACAGTCAGCACATGAACCACCGCTACTCCTACTGCAAGCCGTACAGGGAATAG
Protein Sequence: MLSCLAPSSTRCFGQEDNIIIQQSMPSSTAFSMQFPSLASSLHHHQTTTHNNSQPSNVAAASTEHVAHATSAATANAGDECLVICPQCHKRFNEFQSFSEHIASEHPLDKLNYEQPHPGAAQPESEPEEEDEEEEHSNLSSSSNPRYAKSPSNNNNNNNNSHNNNNNNNNSETAKNQNKRISHSPASLGSPVAPATPSDLFAHLPHPAAHLQFVAAAAMAMQSARSANSPSNQQQQLQQQQQQQHQQQQQQQLLQKPSSNSSSIGSNSAYDLDLSAHRSTSSPGSTAGGDLPAAGFPCMQCTATFHNREQLEQHQLLHSPTRQHTIAQNVKQTCKICHKTFANVYRLQRHMISHDESALLRKFKCNQCEKAFKFKHHLKEHVRIHSGEKPFSCDNCGKRFSHSGSFSSHMTSKKCISMCLKLNNNRQLLKTLDKNAEQLPPTKRSACKQLVEPVLPNLPMNYFAGDSQTSPVGVGVAGGAAAAVPPPPTFYSNYSAMNAALLAFPNAFMAAALDPRMHPYSIQRLLELTAAGQQQHQQQQQREQEEHHREQQELKREQEQELEREQEQEREREQQLQREQQEQQRVREQAQREQLQLLPSKQEDYAEEPKLVMDLEQDAEHPVAAATVETKTAVKMEICRETTPQPTEALKAIKQEREQEQEQEQEEQMELDMQMELEKEQQQQQPPSPVAMPQSSPELRCSRCAKQFNHPTELVQHEKVLCGLIKQELQQQHYQQQQQQQQLQQQQQLQQTPRSLSDYDDDEDVEELLEEPRHADYAAGSSDSNERKVRVRTAINEEQQQQLKQHYAHNPRPSRDEFRRIAAHLQLDARVVQVWFQNNRSRERKMQSYTSGGAGNTETASTILASSAALPPTRGEDQPLDLSLKRDATPPQTQLQLPPDYSEASMAINLSRRQLSGSAASAMSPASLAAAAAATLYFAPTSPTAVPLHNATPPLAAQRGTPFAGLPPFPMMTRLPMEALFQMRPGGEYAPNPLMNSIKLPDYHRGTSLSPGGSEKRSWRDDDSRISHEDDYVLATGGLLAPKPRRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00497631;
90% Identity: iTF_00577278;
80% Identity: iTF_00511172;