Dfor014881.1
Basic Information
- Insect
- Drosophila formosana
- Gene Symbol
- -
- Assembly
- GCA_035045625.1
- Location
- JAWNOW010000814.1:1429205-1438451[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 2.3 1.5e+02 3.1 2.3 3 23 309 331 307 331 0.92 2 11 6.4 4.1e+02 1.7 0.4 3 20 467 484 466 489 0.92 3 11 0.007 0.45 11.0 0.2 2 23 511 533 510 533 0.94 4 11 0.045 2.9 8.5 0.9 1 23 552 575 552 575 0.95 5 11 0.34 22 5.7 0.3 1 22 580 601 580 604 0.90 6 11 0.26 17 6.1 0.5 3 23 657 678 657 678 0.95 7 11 0.28 18 6.0 0.2 1 21 683 703 683 704 0.92 8 11 0.024 1.6 9.3 1.4 1 23 725 747 725 747 0.94 9 11 9e-05 0.0058 17.0 1.4 2 23 762 782 761 782 0.96 10 11 2.5e-05 0.0016 18.7 0.3 1 23 788 811 788 811 0.96 11 11 1.3 83 3.9 0.6 1 11 840 850 840 852 0.84
Sequence Information
- Coding Sequence
- ATGCACAATCCGACGGATGAGCTGGAGGACACGCATCTGTGCATCAGGTGCAATGCGACAATCGTGGGTCTCAGCAAGTACATAGAGCATCGCAAGAGCAATTGCCTGAGCCTGGCCAGAAATCCAAATGCAAACAAGCAagtggcaacgacaacaacaacggcgccCACAGCCGATCACAGCTACGAGGACAGCTTCCACTTCGCAGAGCCCGAGGCGCCGAGCAGCTATTTGCGCAAGACGAGCGCCAGTCATGGCGGCAAGACGTCCAAGTCGCTGACGGAAGCGTACGATGCCAGCTACGAGCCGATGGGCGCCGATGTGTTCTTCTcatcgctgcagctgcagagcgTGTCGACGGGCGGCAAGTCGAGCGCCACACGGCCGGAGCGTGGCAAGGACGAACAGGGCTGGTCCGATCCGCTGCTGAAGGCGATGCGCGAGCACGAGGAGAGCGAGTTTAAGCCCCTGAAATTTGTGCACACGCCGGAGGCGagcgaggacgaggacgacgacgatgacggcgatggcgatggcgatggcgacgagTTCGAGGGCGACGACGATGACCCAGAGCACGATCACGATCACGACCACGACCACGATCACGATGCTGACGAGGATTACGAGGTGGCGCGCCGTCACTCGCCACCCGCCgtgcctgccacacacacgGGCGGCAAGTGGAAGCCGGAGCATCGTCCCCAGTTGCGGCACACGCATCTCGAACGCATCTCGCCCAGCTGGGACGAGCCGCCCGAcgaacagcaaccacaaccacaaccgcaaccacaaccacaacaacacgaCGATCATCCGCCAGCGGAGCATACGCACGGCAAATGGGTGCCGGGCAGCAAGCAGCTGGAGTATCGCGAGAACATCGATCTCACGAAGCTGCAGCAACCGAATGCCAGCTACTGGTGCAACATCTGCTGTCGCCGCCTCAAGACGCGCCTCAACTACGAGCAGCACTTGCGCAGCGCCTACCATCAGCGACGCGCCGAAGCCGAGCGCCAATTGGAGCAGGCGAATCTCGAAGGCGGCAATCTGACGCTCACCAAAGCCTTCCAGCCGGACGAGCAGCGTCGGCGTCGCCAGCGCCATCGTCGCAcgcagctgctgcgctgcgAGCTCTGCCGGCACAGCATGGCCCGCCACCTGATGGGCAAGCACCTCATCTCGCACTATCACTACCgccggctgcagcagcagacgcagccGCGCCGCCAGAACGCGCTCCACGCCATCCTCGAGCACATGGGCAGCATTGTGCGGCAGGCGCCCTTCCAGTGTCTGCCCTGTCGATTCTACGCCAACACCGAGCGGGCTTTCCAGGCTCATTGGCGCTCCGCTTCGCACGTGCAACTGACCGAGCGGCTGGGCGGCGACTTCTGGTGCAGCTACTGCCAATTCGAGTGTGGCAGCAACGAGGCGATGTGGCAGCATCTGGTGGACGCCACGCACAAGGAGGTGCTGCTGGCGCTCAACCGATCCGTGCCCGTTTGCATTGCCCAGCGTCGACGGCTGCGCTGCGGCATCTGCAGCGAGAGCTTCCTCTACAACGTGCAACTGCGTCGTCATCTGGCCAGCGAGCACGTCGGCGTCTCGGCCACAGAGCAGGGCAGCGCAGCGGACGAGTATCAGTGTCGCTTTCGCTGCGACGTCTGTGGCGTGGCACAGAGATCGCGAGTGGCGCTGCAGCGCCATGAGAAGCACAAGCATCGCCTGGCTCGCTACTATTGTGCGCTGTGTCAGCTGCAGTTTGAGACGCCGCTGGAGGCGCGACGCCATCGCAACCTCATGCAGCACAAGCGGCACGCCAAGCGGCAGCTGCCCAAGCGCGACAAGGCGACGGCGCAGCCAGAGCGCGAGCTGGAGCAAATGCTGCGCGAGGTGctcgaggagcagcagccggAAACAGAAACACAATCAGCCGAAATGCTAATGGAGACTAAGAAGCAAGGCTGCGGCAGTTGTGCGCTCAGCTTTGAGACGCCGCAGGCGCTGGTCGAGCACCGACGGCTCTGCCATCCCATGGACAATCACGCCTGCCTcagctgtggcagcagctTCCAGTCCGCCCAGGCGCTGGGGCGGCACACACGCAGCTGCCAGCCTCCCCAGGCCACCACCTccgcctccacctccacctcaaCCTCGAATAATTCGTATCAATGCGATGAATGCGGCTTCAGTGCGCAGTACAAATCGGATCTGCTCTATCATCGTTTCTTTCACACTCGCGACTCTTCGACGGCCATCGGCAAGAACGAACTGCTTCCATGTCCACTGTGCCCCAAGCAGTTCCGCAAGCACTCGCTGCGCGCCCATCTGCGCAATCACACCGACGAGCGCATCTTTGAGTGCGCCGTCTGCTCCTCGAAGTTCGCCAGGCGCAGCAATCTCAAGAATCACATGGCCAGCGTGCACAGCCAGCCGACTACGGCGGCAACAACCCTCAAGGCGAGGAGCCAACAGTTGGCCAGGACGGTTGGGGAGAAGCCTCGCAGGAAATTTCCATGCGACACTTGCGGCAAAACTTTGAACAAAAAGTAA
- Protein Sequence
- MHNPTDELEDTHLCIRCNATIVGLSKYIEHRKSNCLSLARNPNANKQVATTTTTAPTADHSYEDSFHFAEPEAPSSYLRKTSASHGGKTSKSLTEAYDASYEPMGADVFFSSLQLQSVSTGGKSSATRPERGKDEQGWSDPLLKAMREHEESEFKPLKFVHTPEASEDEDDDDDGDGDGDGDEFEGDDDDPEHDHDHDHDHDHDADEDYEVARRHSPPAVPATHTGGKWKPEHRPQLRHTHLERISPSWDEPPDEQQPQPQPQPQPQQHDDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPNASYWCNICCRRLKTRLNYEQHLRSAYHQRRAEAERQLEQANLEGGNLTLTKAFQPDEQRRRRQRHRRTQLLRCELCRHSMARHLMGKHLISHYHYRRLQQQTQPRRQNALHAILEHMGSIVRQAPFQCLPCRFYANTERAFQAHWRSASHVQLTERLGGDFWCSYCQFECGSNEAMWQHLVDATHKEVLLALNRSVPVCIAQRRRLRCGICSESFLYNVQLRRHLASEHVGVSATEQGSAADEYQCRFRCDVCGVAQRSRVALQRHEKHKHRLARYYCALCQLQFETPLEARRHRNLMQHKRHAKRQLPKRDKATAQPERELEQMLREVLEEQQPETETQSAEMLMETKKQGCGSCALSFETPQALVEHRRLCHPMDNHACLSCGSSFQSAQALGRHTRSCQPPQATTSASTSTSTSNNSYQCDECGFSAQYKSDLLYHRFFHTRDSSTAIGKNELLPCPLCPKQFRKHSLRAHLRNHTDERIFECAVCSSKFARRSNLKNHMASVHSQPTTAATTLKARSQQLARTVGEKPRRKFPCDTCGKTLNKK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00472632;
- 90% Identity
- iTF_00614536;
- 80% Identity
- -