Basic Information

Insect: Drosophila formosana
Gene Symbol: ftz-f1
Assembly: GCA_035045625.1
Location: JAWNOW010000705.1:1204539-1219840[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 3 1.7e+04 -9.9 28.4 48 165 25 155 4 165 0.49

2 3 2.5e-19 1.4e-15 57.6 0.5 1 79 328 405 328 423 0.75

3 3 1.2e-72 7.1e-69 233.1 1.2 157 408 548 792 520 794 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	3	1.7e+04	-9.9	28.4	48	165	25	155	4	165	0.49
2	3	2.5e-19	1.4e-15	57.6	0.5	1	79	328	405	328	423	0.75
3	3	1.2e-72	7.1e-69	233.1	1.2	157	408	548	792	520	794	0.91

Sequence Information

Coding Sequence: ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTCTCGCCGTTTAGCATgcagctcgagcagcagcagccagcgagTCCGGCgcacagcaacaccaacaacaacaacaacgccaacaacaacaacaacaacagcagcaacaacagcagcagcaacaacaacaacgataacgaTACAAATGCATTGAGCAACTCTGATAACGATTACAGCGCCTACACGCTGCAGTTGAGcaaccatcaacaacaacagcagcaacagcagcaacatcacacgcatcaccagcaacaacagcaacagcagcagcagcaacaacaacattaccaACAACAGAATattgccaacaacaatgcgaatgCAGCGAACCAATTCAATGCCTCCTCCTACtcgtatatatacaatttcgATTCACAGTATATATTCCCGACAGGCTACCAGGAGACAAACTCCTCGCACTCGCAGCAGAGTGGCAACGGTGGCAACCCCTCGGCCGGCGGCCAGCTGCTGAACGGTGGCAACGCCGGCAGCGCTGGCGGCAACGGTTacatgttgctgccacaggCGGGCGGCACCTCCGCCTCCTCCGGCCACATGTCCGGCAAcgttggcggcggcggcggcggctcgGTCGGCAACGGCCCCTCGGGCGGCACCTCGgccggcggcggtggcggcggcggccatCATGGCGGCACCAGCGCCAGCTCGGGCGGCGGGGAGGCCATCGACTTCAAGCATCTGTTCGAGGAGCTGTGCCCGGTGTGCGGGGACAAGGTGAGCGGCTATCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTTCAGAACAAGAAGGTCTACACCTGCGTCGCGGAGCGATCCTGCCACATCGACAAGACGCAACGCAAGCGCTGTCCATACTGCCGATTCCAGAAGTGCCTCGAGGTGGGCATGAAGCTAGAGGCGGTTCGAGCGGATCGCATGCGTGGGGGACGAAACAAGTTTGGGCCGATGTACAAGCGGGATCGGGCGCGGAAGCTGCAGGTGATGCGGCAGCGTCAGTTGGCGCTCCAGGCGCTGCGCAGTTCAATTGGGTCGGACATCAAGCCGACGCCGCTCTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcaagaaatacaaatacctCAGGTATCCTCACTCACACAGTCGCCGGACTCGTCGCCCAgtcccattgccattgccttgGGGCAGGTGAATGCGAGCGggggcggcggtggcggtgtgATAGCCACGCCCATGAATGCCGGCAACGTGAGTGGCGGTGGCAACGGCAGCTCCTCcttgggcggcggcggcaacaacagcaacaacaacaacaacaatggcaacaacaacagcagcagcagcacaggcagcggcggcagcgccGGCGGCGGAGGTGGCAACAACGCTGGCGGCGgcgccggcggcggcggcggaggcggcaacaacaacaacagctccgATGGCCTGCAACGCAACGGAAACggcggcaatggcaacagcaacagcagctgccacgAAACCGGCACGGGATCTCTGCAGAACACAGCCGAATCGAAATTGTGCTTCGATTCTGGCACGCATCCATCGAGCACAGCCGATGCGCTCATCGAGCCTCTGAGggtatcgcCAATGATACGTGAATTTGTGCAATCGATCGACGATCGGGAATGGCAGACACAACTGTTTGCACTGCTGCAGAAGCAGACGTACAATCAAGTAACCGTGGATCTCTTTGAGCTGATGTGCAAAGTGCTCGATCAGAATCTGTTCTCGCAAGTGGATTGGGCAAGAAACACGGTCTTCTTTAAGGATCTGAAGGTTGACGATCAAatgaagctgctgcagcattcGTGGTCGGACATGCTTGTGCTGGACCATCTGCACCATCGCATCCACAACGGGTTGCCCGACGAGACGCAACTGAACAACGGGCAGGTGTTCGATTTGATGAGCCTGGGGCTGTTGGGGGTGCCACAGTTGGGCGACTACTTCAACGAGATACAGAACAAGCTGCAGGACCTTAAGTTCGATATGGGCGATTATGTGTGCATGAAATTCCTAATACTGTTAAATCCAGATGTACGCGGCATTGTCAACAAGAAGACCGTCTTGGAGGGGCACGAGAATGTGCAGGCTGCGCTGCTGGATTACACGCTCACGTGTTATCCCTCAGTCAATGACAAATTCAGGAGGCTATTGAACATACTACCAGAGATCCACGCCATGGCCTCCCGTGGCGAGGAGTATCTGTACACAAAGCACTGTGCGGGCAGTGCGCCAACGCAGACGCTGCTCATGGAGATGCTGCACGCCAAGCGGAAGGTGTAA
Protein Sequence: MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNTNNNNNANNNNNNSSNNSSSNNNNDNDTNALSNSDNDYSAYTLQLSNHQQQQQQQQQHHTHHQQQQQQQQQQQQHYQQQNIANNNANAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSGNGGNPSAGGQLLNGGNAGSAGGNGYMLLPQAGGTSASSGHMSGNVGGGGGGSVGNGPSGGTSAGGGGGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGSDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGGGGVIATPMNAGNVSGGGNGSSSLGGGGNNSNNNNNNGNNNSSSSTGSGGSAGGGGGNNAGGGAGGGGGGGNNNNSSDGLQRNGNGGNGNSNSSCHETGTGSLQNTAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVTVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFDLMSLGLLGVPQLGDYFNEIQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMASRGEEYLYTKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00562522;
90% Identity: iTF_00520662;
80% Identity: iTF_00509151;