Dfla005354.1
Basic Information
- Insect
- Drosophila flavopinicola
- Gene Symbol
- HmgD
- Assembly
- GCA_035042425.1
- Location
- JAWNLL010000206.1:431201-431640[+]
Transcription Factor Domain
- TF Family
- HMG
- Domain
- HMG_box domain
- PFAM
- PF00505
- TF Group
- Other Alpha-Helix Group
- Description
- High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 4e-23 2.1e-20 72.9 0.6 1 68 5 70 5 71 0.98
Sequence Information
- Coding Sequence
- atggcCGACAAACCAAAACGTCCACTCTCCGCTTACATGCTGTGGCTGAATAGCGCACGCGAGTCGATCAAACGCGAGAATCCCGGCATCAAAGTGACCGAGGTGGCCAAGCGCGGTGGTGAATTATGGAGGGGCATGAAGGATAAGTCGGAGTGGGAGGCAAAGGCGGCCAAGGCTAAGGACGATTACGATCGTGCCGTCAAGGACTTCGAGGCCAACGGTGGCAGCACTGCCGCCAATGGCGGTGGTAGCAGTGCCAAGAAGCGCTCCAAGCCTGCGAAAAAACCAgcgaaaaaaagcaaaaaagatgACTctgacgacgatgatgatgatgagagCGAGTAA
- Protein Sequence
- MADKPKRPLSAYMLWLNSARESIKRENPGIKVTEVAKRGGELWRGMKDKSEWEAKAAKAKDDYDRAVKDFEANGGSTAANGGGSSAKKRSKPAKKPAKKSKKDDSDDDDDDESE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01557533;
- 90% Identity
- iTF_00583649; iTF_00537484; iTF_00589517; iTF_00614157; iTF_00509073; iTF_00520602; iTF_01327137; iTF_01324866; iTF_00541731; iTF_01325635; iTF_00561007; iTF_00495830; iTF_01320443; iTF_00530236; iTF_00506082; iTF_00575553; iTF_00616872; iTF_00530924; iTF_00563148; iTF_00506833; iTF_00805937; iTF_00522930; iTF_00585938; iTF_00567507; iTF_00475188; iTF_00526549; iTF_00550869; iTF_01323349; iTF_00534551; iTF_00538199; iTF_00490750; iTF_01326366; iTF_00601760; iTF_00543714; iTF_01321891; iTF_00533772; iTF_00566764; iTF_00497358; iTF_00585167; iTF_00511248; iTF_01324081; iTF_00552275; iTF_00500280; iTF_00498844; iTF_00557884; iTF_00608412; iTF_00514148; iTF_00499557; iTF_00598853; iTF_00574022; iTF_00485831; iTF_00616169; iTF_00542410; iTF_00560234; iTF_00558635; iTF_00577035; iTF_00518412; iTF_00555820; iTF_00495085; iTF_00521325; iTF_00564622; iTF_00501775; iTF_00553008; iTF_00582930; iTF_00593074; iTF_00528020; iTF_00513429; iTF_00597334; iTF_00496571; iTF_00557179; iTF_00576316; iTF_00482205; iTF_00570367; iTF_00609856; iTF_01556805; iTF_00915303; iTF_00914472; iTF_00598121; iTF_00918058; iTF_01550250; iTF_01552427; iTF_00919790; iTF_00919791; iTF_00919025; iTF_01553937; iTF_01559729; iTF_00917176; iTF_01555384; iTF_01558264; iTF_01550971; iTF_01548828; iTF_00610621; iTF_01557533; iTF_00336704; iTF_00478694; iTF_00584396; iTF_00568948; iTF_00470840; iTF_00528775; iTF_00587368; iTF_00588808; iTF_01321161; iTF_01553198; iTF_01554670; iTF_01327860; iTF_01559005; iTF_00802815; iTF_00802816; iTF_00548775; iTF_00525098; iTF_00522143; iTF_01549545; iTF_00618369; iTF_00553706; iTF_00562443; iTF_00472336; iTF_00556499; iTF_00535281; iTF_00580691; iTF_00480833; iTF_00487266; iTF_00563874; iTF_00601026; iTF_00474473; iTF_00514860; iTF_00536014; iTF_00517680; iTF_00603314; iTF_00473751; iTF_00611320; iTF_00484413; iTF_00471583; iTF_00574783; iTF_00545208; iTF_00544461; iTF_01551704; iTF_00509786; iTF_01556093; iTF_00359424; iTF_00595217;
- 80% Identity
- -