Basic Information

Insect: Drosophila ezoana
Gene Symbol: -
Assembly: GCA_035045725.1
Location: JAWNOU010000207.1:3042685-3046590[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00046 0.033 14.8 0.1 1 23 158 181 158 181 0.96

2 15 0.0016 0.11 13.1 2.9 2 23 230 252 226 252 0.89

3 15 0.014 0.98 10.2 0.9 1 23 358 381 358 381 0.93

4 15 0.57 41 5.1 5.8 2 23 430 452 429 453 0.95

5 15 0.0036 0.26 12.0 0.5 1 23 515 538 515 538 0.88

6 15 2.2 1.6e+02 3.2 0.1 2 14 557 569 556 581 0.85

7 15 0.00077 0.055 14.1 3.3 2 23 589 611 589 611 0.96

8 15 0.00088 0.062 13.9 0.1 1 23 719 742 719 742 0.95

9 15 9.3e-05 0.0066 17.0 0.3 1 23 795 818 795 818 0.93

10 15 0.0013 0.092 13.4 2.2 2 23 868 890 867 890 0.97

11 15 0.0021 0.15 12.8 2.0 1 23 972 995 972 995 0.92

12 15 0.15 11 6.9 1.5 1 21 1047 1067 1047 1068 0.95

13 15 0.57 41 5.1 0.1 2 23 1111 1135 1110 1135 0.80

14 15 8 5.7e+02 1.5 0.4 1 9 1153 1161 1153 1177 0.68

15 15 1.9 1.4e+02 3.4 0.9 10 23 1207 1221 1206 1221 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00046	0.033	14.8	0.1	1	23	158	181	158	181	0.96
2	15	0.0016	0.11	13.1	2.9	2	23	230	252	226	252	0.89
3	15	0.014	0.98	10.2	0.9	1	23	358	381	358	381	0.93
4	15	0.57	41	5.1	5.8	2	23	430	452	429	453	0.95
5	15	0.0036	0.26	12.0	0.5	1	23	515	538	515	538	0.88
6	15	2.2	1.6e+02	3.2	0.1	2	14	557	569	556	581	0.85
7	15	0.00077	0.055	14.1	3.3	2	23	589	611	589	611	0.96
8	15	0.00088	0.062	13.9	0.1	1	23	719	742	719	742	0.95
9	15	9.3e-05	0.0066	17.0	0.3	1	23	795	818	795	818	0.93
10	15	0.0013	0.092	13.4	2.2	2	23	868	890	867	890	0.97
11	15	0.0021	0.15	12.8	2.0	1	23	972	995	972	995	0.92
12	15	0.15	11	6.9	1.5	1	21	1047	1067	1047	1068	0.95
13	15	0.57	41	5.1	0.1	2	23	1111	1135	1110	1135	0.80
14	15	8	5.7e+02	1.5	0.4	1	9	1153	1161	1153	1177	0.68
15	15	1.9	1.4e+02	3.4	0.9	10	23	1207	1221	1206	1221	0.84

Sequence Information

Coding Sequence: ATGGAAGGTATGGACCTGTGGACGTCCATGTTTTCAGCCGATTTCGATGAGGGCGACGGTGAGGTAGAGAGTCCCAATAACGGTAACAGCGCGCTGGCAGACGAGTTTATGGgcgaagaggaggaggaggaacaAGAGGCTGAAGAGGATGAGGGTGAAGACAGAGACAGCAAGCGCAAAGGACACGAGCCCGATGACGATGCCATATTTGACTTTGAGCTAGAGCCAATTGTTAGCATTGcggaaccagaaccagaacctgTGCCAAGATCAACGGTCCCCCTGGCGCCACCAATGCCAGCGGGTCCAGCCATCCGACCACAGCACCGCCAATCGTTGCCAGCATCGTTTGGCTCGCAGTTGATAATGGGTCGCGGCGGTGCAGGCGTTCCACCCACACGACCAACGACCTCACAAATCAATGCAACCGATGAGAACGGTGTGCCCATTAATTATGAGCTGGGCGTCATCTATATATGCCCCGCCTGCGGTGCCGAGTATCGGCAGCAGGACATGTGGAAGCGTCACATGAACCAGATGCATCAGTATAATACGCGACGGGGTCTTAATTTCGTGGCCATTGATAAGCTGTATCATCGGTGCTTGGAATGCAATAAGCGCATCGCAATGCACAGTCGGGAGAATCTTCTGAAGCACAAGTTCACCCATTTGCCATACCGTTGCACCAAGTGCTACATCTGTAAGCGCGAGTACAAGTACAGGCAGGACCTAATGGTGCATTTGCGCATGGTGCACTGTGACGAAGTGGTGGCCATGATGCGCGGCGGGGATGCCAGTGCCGGACGCAAGACACGTGTTCGGGAGCCGCGCATTGAGCAGCATCATAGATCCTACGGGCCGGAacatgacgatgacgacggcATTGAGGTCAAGAATGAGCTGATGTTGGAGGCGGAGGGTGGCGTGCAGGCAGCTGATGAGTCCAACTTTGGTTTGAATGATGAGCACAGTCGCAGCTCCAGTCAAGCGGCTAAGAAGAAGCGCGGCACTGCTGTAGCTGGCAATGGAAGTGGAAGCAGTGCAGCAGACATCTGCGAAGATTATATACACTATATGTGTCCCGACTGCGGCACCGATTGCGATACACACGCCCAATGGAGTCAACATATTGAATTTGTGCACGACTATGTCAGTCGGCGAGGGCTGAACTTTCGCTGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAGCAGTTTGTCATTCCGAACACGATAAAGACGCTGCGGGCGCACAAGTTTAGCCATTTACCTCAGCCGGAGTGGATGCGCTGCAAGCTGTGCTATCAGGGCTTTACGGAGCATCATGAGCTGCTCACGCATCTACTGAAGCAGCATCATTTGGAAACCTTAATGCCTGACAAGGAGGAGGAGCACCCATTGCCCACAGCCGTTGCTGTGGGTGATGAGGGCGAGGATACTCCAGGCATTGGCGGCGATGAGGAATCTCAGTTGCAATGGGACGATGTGCCGCGACGTGGCGGCCGCATTGGCAGCGATGATATGTACGAGCCGCATATTGATTACCTGTGCCCGCAGTGCGGCAGGGAGTTTATAGAGAAGAAGCACTGGCGTACACATGTTGTCCAGGTGCACGGCATGAACGATCTGGCCAAGTTGAACTTCGAGGTGATCAACGATCGCCAGCTGAAATGCACCGAGTGCGATAAGATCATAACGAACGCTTATGGCATACAGAATGCCCAGCAGCACAGGATAACGCATTTGCCCTACAAGGCGTACGCGAGATGCCGTAAATGCCATAAATCCTACACGGATCGCAAGGGTCTGGTCAAACATTTGGCCACATACCATCGCGTCGGCTATGAACCACGCAAAGTGGGCGCCGTGCTAGGCACAGGTACAGGCACACCATTGGTCATGGCCTTAAACCCAGCCAAATCACAGACGCCGCGCAAACAAATTGTCACTGTGGCCAATGAAACCTATGAGATTATATATTTGGATGAGGAACAATCGCCGCcaagcaataataatattaatgagGAGAATGACTTTGGAGAGCAAATGCAGgcggatgatgatgattatgcCATCGTAGGCAGCACCAGCGGCAGCATGGGACGCCAGCTGCCACCAATTGCCGCAGCTGCCGAGGCACCAAATCCCAATCGCTACAAATGTGTGGACTGCGGCTCACTGTTTGCTACGCAGGCGGCGCTGAAGACGCACATCAGCGAGGAGCATGATTTCATGGACACACAATATAGCGCCAAAAAGTTTGATAATGCGGAGCCCTCAGAGGAGGCAACTCCAGCTGCGCCAGTTGCCGTGACGACAGCAGCCAGTGCTATGCCCGCCAAGAACAGCGCCGGCGCCTCGACCATAGAACAGAATTATATATTCCTGTGCCCGTCATGCGGCAAGGCCTACAAGACGCAGTTCGAGTGGCGACGTCACATCAACGAGGAGCACAATTTCGACAAGCGACAATACTTAAATATGCGCCAGCTGGACAAGTATCGCTATCAGTGCACCCTGTGCAAGGATATTGTGTGCAATTCGAAGCTGAAAGGCCTGCAGGATCATCATTTTCGTCATTTGCCTTATCGCCTATATCTGAAGTGTCTGGTGTGCGGCACCTGCTACAATCACAAGCCCAACATTGCGGCACATCTGCGCACACGACACAACATCTACGAACGTGAGTCCTCGTGGCGTGAACACCAACCCAAGACCCAGAATGGCTACGAACAGCTCAAGTATAAGGATAATAAGGATAGGGACATGCAGACCAGCTCAGGATCACCAACACCCAGCAGCAGTCGCACGCTCAAACCGCAACCGGGCGTGATGCCCACGCGTCCCGCTGGCCTCAATACGCTGGAGGACAGCATCTCGTATCATAATGCTGTGGATCTGGACTTTATAACCTACTATTGCCCCAAGTGCAACAAAAACTTTGATTCGCACGCCTTCTGGCGCAAACACATTGTCGAGCAGCACAACTATAACAGTCGGCAGGGCCTGAACTTTCGCCAGATTGACAACCATCACTATTTGTGCCTGGAGTGCTATAAGCGTGTGACTGTGACTCACACCAAGGGCGCAATTGGGCAGCTGCAGTCGCACAAGTTCCGGCATTTGCCGTATCGCTCCTTTAAGTGCTTGACCTGCAGCGGCGAGTTTGTGCGCAAGCAAATGTTCTTCAAGCATTTGAATCGGGACACCAATCGCTGTGACAACAAGCCAATGAGTTGCCATGATAATGATGAGGATACAGGGGAGCAGCCGGACAGGCCAGTTGCCATTCCCGTTAAGGCGGCACTTGATGGCGACACGTATCGTCTGATGTGCCCGCAGTGTGGTGATGGCTTcaccaccagcagcaaagCTCTCTGGCGGGAGCACATAAATATCTATCATGGTCTGGGCAAGCGCGATCTGCTGCATATGCGTAAACTGGGCGAGGAACTGTATCGCTGCACCGACTgtgaggagcagctgcagacCAAACAGCTGCgtgtgctgcagcagcatcgcTTCCAGCATTTGCCCTATGCCGCCTACATACGCTGCCAGCTGtgcgaacagcagcaaccgccGGATGGACTGGGTCatggcgcagctgctgccggaTTTCATAGTATGCGCGAACTGCAGCAGCACATGCGTACCGAGCACCCCAATGTGGCGGAGCATGATGACCAAATGCAATCGCTGCTGGAGGATGAAGAGGTGGAAGATGTTCAGCAGCCGGCGGCTAACAGTGAGACGTCGGAAAATGGTCCATATATGCCATTACCGCCGCATTTGCTGGACGATGATGTGGACGACATGGAGTTCGAGGAGCAGTATCTGCTGGGCTAA
Protein Sequence: MEGMDLWTSMFSADFDEGDGEVESPNNGNSALADEFMGEEEEEEQEAEEDEGEDRDSKRKGHEPDDDAIFDFELEPIVSIAEPEPEPVPRSTVPLAPPMPAGPAIRPQHRQSLPASFGSQLIMGRGGAGVPPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMRGGDASAGRKTRVREPRIEQHHRSYGPEHDDDDGIEVKNELMLEAEGGVQAADESNFGLNDEHSRSSSQAAKKKRGTAVAGNGSGSSAADICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFSHLPQPEWMRCKLCYQGFTEHHELLTHLLKQHHLETLMPDKEEEHPLPTAVAVGDEGEDTPGIGGDEESQLQWDDVPRRGGRIGSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLAKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKVGAVLGTGTGTPLVMALNPAKSQTPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAIVGSTSGSMGRQLPPIAAAAEAPNPNRYKCVDCGSLFATQAALKTHISEEHDFMDTQYSAKKFDNAEPSEEATPAAPVAVTTAASAMPAKNSAGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERESSWREHQPKTQNGYEQLKYKDNKDRDMQTSSGSPTPSSSRTLKPQPGVMPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGEFVRKQMFFKHLNRDTNRCDNKPMSCHDNDEDTGEQPDRPVAIPVKAALDGDTYRLMCPQCGDGFTTSSKALWREHINIYHGLGKRDLLHMRKLGEELYRCTDCEEQLQTKQLRVLQQHRFQHLPYAAYIRCQLCEQQQPPDGLGHGAAAAGFHSMRELQQHMRTEHPNVAEHDDQMQSLLEDEEVEDVQQPAANSETSENGPYMPLPPHLLDDDVDDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00551114;
80% Identity: -