Dkan007029.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kanekoi
Gene Symbol
hang
Assembly
GCA_037075305.1
Location
JBAMCE010000290.1:2732369-2748372[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.4 26 5.6 1.0 3 23 521 542 520 542 0.93
2 18 1.2 76 4.1 3.2 3 22 649 668 647 668 0.89
3 18 0.00086 0.057 14.0 3.3 1 22 770 791 770 793 0.90
4 18 0.099 6.5 7.5 0.1 2 21 805 824 804 825 0.93
5 18 0.001 0.066 13.8 0.2 2 23 951 973 950 973 0.95
6 18 0.0029 0.19 12.3 0.1 1 23 981 1004 981 1004 0.96
7 18 0.00022 0.014 15.8 0.2 2 23 1090 1111 1089 1111 0.97
8 18 0.00041 0.027 15.0 2.9 2 23 1232 1254 1231 1254 0.97
9 18 0.032 2.1 9.0 0.2 2 23 1263 1285 1262 1285 0.95
10 18 0.0017 0.11 13.0 0.1 1 23 1298 1321 1298 1321 0.97
11 18 0.00018 0.012 16.1 1.1 1 23 1362 1384 1362 1384 0.99
12 18 0.0028 0.18 12.4 0.9 1 23 1392 1415 1392 1415 0.96
13 18 0.097 6.4 7.5 0.4 2 19 1423 1440 1423 1441 0.94
14 18 0.0001 0.0068 16.9 0.4 3 23 1535 1555 1534 1555 0.98
15 18 0.0072 0.48 11.1 0.1 1 23 1590 1612 1590 1612 0.97
16 18 0.00085 0.056 14.0 0.6 2 23 1696 1718 1695 1718 0.93
17 18 0.0092 0.61 10.7 0.3 3 23 1774 1794 1774 1794 0.98
18 18 0.0001 0.0067 16.9 2.0 1 23 2254 2276 2254 2276 0.99

Sequence Information

Coding Sequence
ATGTGCGACGCTGTCGCAACTACAACCtcaaccgcaacaacagcagcagcaggatctggaacaggaacaggaacggctggtgctgctgctggcgataCAGCGACAGCAATGGAGGAGCGTACGCGACAAAGCTGCTGTCGCCTATGCATAGCGCCCGCCAGCGAGTGCATTTCGATCATTAACAGTTATGCGGCCGATAAGGAGCCACTGGCCACTAAAATACACAACTGCGTAAATATCAAGATCACGCCGTTGGATCGTCTATCGCTGCATATTTGCCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCACAGTCCAAGCAGCGGCAATGGCTGGACACCGATAAAAGCAAGCAGCAGACACTACTAGGATATTTGGATTTGAACAAAACGGAGAATGGCAGCTCCATTGAACAGCAGCACGAAACGAACATCGATTCGGCGACAGTTGCAGCTGAAAAGGCGTCCGCCAACATATTGGATGGCATACCCTCGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCcaaagcaacagctacaacagcaacaacagcaacaacagctacaacaacaacatcagcaacaacaacagcagcagcagcagcaacagaatgCTGTTAGAACGACGAGCGCGGCGGCGGAGTCACAGCAAACACTGCAAACCCTTTTATTGCAGGTGCCCTCAGCAACATTGTCAACGGCGTcaactcagcagcagcagcagcgcaaatatcaacagcagcagcaacgtggcaggcagcaacattaccaccagcagcagcaacatcagcagcagcagcaacatcagcagcagcaacaacaacaacaacaacatcaacagcagcagcagcagcgactaaGTCGAATGCGTCAACcgcgacgccagcagcaggcggcaacgTCTGCTCAGCGTTTGGCTAAGTTTAAGCCTAAATTGTATTTACCATTGGATATATCAGTGCCGCCGCTTCCAccgttgctgccgccgccgttgccgcccATGTTGTCAACtattgttgctggtgctgatTTAGCGCCGTTGCCAGTGCCGTTGTCGCTGCCACTTGATTTCAGCCAGAGTCAGTGTCCGAATCCGAACGCGAATCAGAGTCACAAACATAGCAGCGTGttgccaccaccgccgccgccgccgcttccGCTGGCTCCAGTTGCAGCAATGACCAGCAacgcctctgcctctgccactgccactgccactggctctgccgcagccgcagtcacGACTCCATTGCTCATGCCGCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCCATTGACGATACGGATGATGACTTCCAAATGAAGTGCATAGACGAATCCGATGACATGATGGATCCAACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACACGGCGCAGCATGGCGTGACGGCGGTTGTGGCGGCGGCATCGCTGCCCGCCAGCGCGGTTGCGAATGTGGCCGCCGCTGGCGACTCCAAGGTGGCCAGCTGCCGTGCCTGCAGTCTGCAGTTCTCGACGCGCGCGAATGCGCGACGCCACGAGCGCAATCTCCATCCGAATCTGTTCCAGTTGTCGACGGACTCGCCAAATAATACGCCCATCACAAAACCGACGCCGGCATTGGCAGCCGCGCTGGAGATACAGCgtgcagcagccgcggcagcgGCCACCGCGGAGGCAACCAAAGCTGCCGCCGGTGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTCATGAACACGTTCATAAAGTGCGAGAACGGCGGCTTCGACTACGACAATCCGGAACAGTATCAGCAGCTGCTCACCCGCGACAAGGTTGAGTTCATTCAGGAGAACAACGAGTTTCTGGAGCAGTACCAGACGATgacctgccgctgctgcaacaaATACTTTAATACATACAAGAACTTTATGGCGCACGTACGCAAAAAGTATCCGCTGCTGCCGCGCAATTTGTGCTTCAACTGCCTAAAGATGAACGACTCCAAGGCATTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGCGTTCTTAACGCTCTACGCAACAAGCAGCCAAACTTCTCTCATGCCACCGCATCCGGATCGGCTGTCTCAATCGATATGAGTGGTGTTccaggtgctgctgctgctgctactgcagcAGGGGCAACAGCACACGAAACATCAATGGAACGGCCTGAGAAGCTACGCGCCAAGGAGCTGCTGGTGAACAAACTGTATGAGTGCAAGCTCTGCCCAAAGGGCTTTCGCACCAAGCACGAGTTCCGCACGCATGTGTACGACAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGACTGGACTTTGCCGATCCGGTTGATCGTCGCCGTCACTACAACAACATGGACTGCATTGTGCGGCTACGCTGCATGACCTGCGATGCCAAGCTGGAGACGCATCAGCGCTTCCTCGATCATGTCTATCAGGATCATTTGGGCGGCGTCAGCAGCGACAATGCGTCCACCGCGAACAGCGGCATGGATCATTCGCCCGGCAAGCGTAGCCTGCTGGGCGCCCTTGGCATTggtgtcagtcagtcatccaATGATGAgtcacgcagcagcagccacaacaacaacaatgccgtGGAAACGCCGCTCACCTCAACACCGAAACCGGCTGCATCGGGAAGTGCAGCTGCGGCGGCGACCAGTGGTGGCTCCACATCTGGCAATCGCGATGCCCCCAAATCGCAGTATTTTTCCCGCATGCCGCAGGTGTGCCCCATTTGTGGCCAGCAGTATAATAACTACAACAACGTGCTGCGCCACATGGAGTCAAAACATCCCAATAAACTGCCCGAGACGTACAAATGTGTACGCTGCGGCCTGGGCTATCCGCGAATCTCATATCTGCGCGAGCACATGATTAATGTGCATGGCGTGGACAAGAATCGGCATTCCGGAGGCTTTGAATATATTGTGAATGCCGATGCTGTTAAATTGGCGGACGGCAGCACGCCCAATGTCTATACCGGGCGCTATGattatgtgatgaaggatCTGATGTCAATAACAAATGGTGGGACACTcgatgatgaggaggaggagagcGGCAGCGTTGCCAAGAAGATGCGCCTCgatgacagcagcaacaacagcagcatcaacatgAGCATCGCCAATCAGCAAAAGGAATGCCTCATCTGCAACGCGGTgttcagcaacaacattggGCTATCCAATCACATGCGCTCGCATTATACCGCCTCCACGACGACGAGTGCTGCGCTGGCGGTGGCCAATCGCATGACGCCAAAGTCGCTGACTATTACCGCAACGCCGCCGCTGGAAACGGCTGCCGCATCGTCCACAAGCATTGCGgtgtcagcagcagcggcggcggcaacagcagcagcagcaacagcaacagcaacacccgTCAcaagctcagctgctgctgcgagtgcaactacaacaacaagtacaacatctgccgccgccgccgctgcgtCCGCGTCCGGCAGTTTGCCGCCCGCGATGGCACATCAAACGCCACAGGAGCAGGCGGTATTCCGACGTAGCCTGGATCAGGCAGCCGATCGTCGCTTTCGGCGCATGCGCTGTCGCATCTGCCAGCGCAGGTTTAGCTCGAAGAAATCGTACCGCTACCACATGCTTACCGATCATCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTCGCCTACGAAAAGGGCCTCAAGGTGCATCTCTTCAAGGTGCACGGACGGGCCATTAAAGACGAGATGATTGTGAAGCAGTTCGAGTGCGATATCTGTTCCATTGTCTACAGCTctgagctggagctgcagcagcacaagcGCAGCGTGCACAAGTCGCAGCTGGGTGCCAACGATGCGGCCAAGTTAAAATCGTCAACCGCTtcctcagcctcagctgctGACCTTGCCGATACGTCCGGCTCGGCTGTGCCGGTCCTGCCCCTTTACTGGTACCAGTGCAAGTACTGTCCATCCAATTTCAACACCAACAAAAAACTAGCCATACACATCAACTCGCACGACGAGTTTGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGTGGCCGCAAAAGCCTTTGGgtGCATCGCTATAAGAAGCATCCGCAGGTGCCGGATCCCGCTGAGTGTACGCTTTGCCGCAAGATGTTCTTTGACCGCCAGATGCTGGAGAATCACACGCCAACCTGCAACCGGAAGCCCATCACTGCCACCGGCGCCCATCAGCAGGattcgcagcagcaacagcaccagcagcagcagctgcagatgcagcagcagcgcggcaTATTCAAGCACAAAACGGGCGACgatgacgaggaggaggatgatGATCAGCTGATGGTGCTGGACGATGGCGTCGGCAGTAGCAGCAACGGCGGCAatgctgccacagcagcagcagcaggatcagGCAATGCGAATAGCAGCACATTGAAGATACGCATACCGGAGGTGGCATGCACCATTTGCGGTGCCCGGTTCACCGATCAGGAGATGTTCAGCAAGCATATACAGAAACATGAACAGGATCTGTATGTGGATAATCCATTGGCGGCCATGTTCGATGATGGACCAGCGGACGCTGGCCAATTTCAGGTGGAGCGCCAGAACGAGAACGGCGAATATGCGTGCGATCTGTGCGCCAAGACGTTCCCCCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaATCCCATCATCGACGGCGAAGCGACAACGgtgaacaacagcaacaacaacaacaacaattcgctGAGCTCCTCATCGATGCTCCATCTGCGCGAACTGCATGCTGTGGGCCTGATGCCCAATCAGCAGcaccagaaacaacaacaacaacagcaacaacaacaacaacagcagcaacaacaacatcagcagcagcagaggaagTCGCTGAAACGGAAACGTGAACTGAAATGCGAATATTGCGCATCCACATtcattagcaacaacaacctgcGTCGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAATCTACCGGAGCCGCCAGTGATTGAAGTGGATGAGCCTTTAACTTGTCGCCGTTGCGGCGATCTGCGGTTTGATACCAAAGAGCTGTGGATCGAGCATAAATTGGCCGATGCCAAAGTTGTGCGTCCGTTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTATCTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAAGAGGATGTAATTGTGCctgtggcggtggcggtggcggtggccaCCAAGCCAGCATCAGCAGTCCCCAGCaagaatgcaacaacaaaatcttcagcaacaacagcaacagcagcggcagcaacaggagcCACAAAGGGCATAATAAGAGCGGGAGGAGCAGTAAAAgtgcttaaaaacaaacaattggaTGACCTGCATGAGCAGCTAGACATGAAAGTGTCGAAGCTGtctaaacagcagcaaaatgttCATGTGGCGCACAATGATGAGGAGGAAGCggggcagcaggagcagcaggaggcgGATGATAGTGATATGGATGATGATAGCGATAGTGGCGAGGATGATGAGGATAGCACAAGcgctgatgatgacgacgacgatgatgatgataacgatgatgatgatgacgacgacgatgagggCGATGtggacgatgacgatgacgaagATATTGTAGAacaccagctgctgcaacaacaacaacaacaacaacagtctctcaatagcaacaacaagaacaacaacaacaacagcgtaGTTGCaaatgacgatgacgatgatctCATTGAAGAGGTAATCGAGGATGATGGCATTGTCGAAGAGCTAgaagatgatgaagatgatgacgaggaggacgaggacgaggccGATggcgttgatgatgatgacgacgacgatggtAACACAACGGATGAGCACCAGGTGCTGCCTTCTAATACCACCAAACAGCAGCCGAGGCGCCTCAACTTTGACTACACGCGCACAGACAGCTCCAAGCTgaacggcaatggcaatggcaaacaGACGCCGCAGAAACATCAGCAAAAGTCAAAGGGTCAGCAGACGCAGGTGCTGGTCGTGCATAGCTCAgaggatgaggatgacgaCGCGGAGGCTGATGTCGATGGTGATGTTGATGAGGATGTAGATGATgtggatgatgatgaggaggaggtagaggaggaggagggcgTGGGTGAAGCAATGACCATTGATGATATTATTGAAGAAGATGATGGGGAGGATGATGACGATGTGGTTGGTGTCGATGGTGGTGTTGttgaggatgatgatgatgatgttgacgAAGATATGGACGAGGATGACGTTGACGaggacgatgatgacgacgacgacgatggtggtggtggtgctgctgttggtcgTCTCGCTGGCGCCgccagtggcagcggcagcggcagtctCATCGGCGCGTCTGATGGTGTGGCTGCTGATGCCGATGGTGGTACATCATCATCTGAGAGcgagtcaacaacaacaacatcgcaTTCAATTGGTGAGCGGCGTAAAAAAACAGTAGTTAAATCAGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGTTACTGCAGTCACATATTAAAAGCCATTTTCTGAATGGCCCGTCGGCGGGCAGCGGCAGTGCCaacgccagcggcagcagtagcagcagagGCGCCAGcctcggcggcggcagcggcagcgctagcggcagcagaaacaacaatcataataataacaacatcgacagcagcagcagcggcagcagcagctgcagtagcagcagcagcagcaacaacaaaaccaaaaccaaaaagtcCGGCTTGGATGCAATCAAAAGTGGCagtgctgctgcaacagcgtCGACGACAACGTCGacagctacaacaacgacaacagcaaaaggtgcagctgaggcagctgcaacaacagcagcagcggacgCTGCAAACAGCTTGAACTGA
Protein Sequence
MCDAVATTTSTATTAAAGSGTGTGTAGAAAGDTATAMEERTRQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLDTDKSKQQTLLGYLDLNKTENGSSIEQQHETNIDSATVAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQQQLQQQHQQQQQQQQQQQNAVRTTSAAAESQQTLQTLLLQVPSATLSTASTQQQQQRKYQQQQQRGRQQHYHQQQQHQQQQQHQQQQQQQQQHQQQQQQRLSRMRQPRRQQQAATSAQRLAKFKPKLYLPLDISVPPLPPLLPPPLPPMLSTIVAGADLAPLPVPLSLPLDFSQSQCPNPNANQSHKHSSVLPPPPPPPLPLAPVAAMTSNASASATATATGSAAAAVTTPLLMPPLPAVPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRNKQPNFSHATASGSAVSIDMSGVPGAAAAATAAGATAHETSMERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSSHNNNNAVETPLTSTPKPAASGSAAAAATSGGSTSGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEEEESGSVAKKMRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTASTTTSAALAVANRMTPKSLTITATPPLETAAASSTSIAVSAAAAAATAAAATATATPVTSSAAAASATTTTSTTSAAAAAASASGSLPPAMAHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSSELELQQHKRSVHKSQLGANDAAKLKSSTASSASAADLADTSGSAVPVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDSQQQQHQQQQLQMQQQRGIFKHKTGDDDEEEDDDQLMVLDDGVGSSSNGGNAATAAAAGSGNANSSTLKIRIPEVACTICGARFTDQEMFSKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTVNNSNNNNNNSLSSSSMLHLRELHAVGLMPNQQHQKQQQQQQQQQQQQQQQHQQQQRKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAVAVAVATKPASAVPSKNATTKSSATTATAAAATGATKGIIRAGGAVKVLKNKQLDDLHEQLDMKVSKLSKQQQNVHVAHNDEEEAGQQEQQEADDSDMDDDSDSGEDDEDSTSADDDDDDDDDNDDDDDDDDEGDVDDDDDEDIVEHQLLQQQQQQQQSLNSNNKNNNNNSVVANDDDDDLIEEVIEDDGIVEELEDDEDDDEEDEDEADGVDDDDDDDGNTTDEHQVLPSNTTKQQPRRLNFDYTRTDSSKLNGNGNGKQTPQKHQQKSKGQQTQVLVVHSSEDEDDDAEADVDGDVDEDVDDVDDDEEEVEEEEGVGEAMTIDDIIEEDDGEDDDDVVGVDGGVVEDDDDDVDEDMDEDDVDEDDDDDDDDGGGGAAVGRLAGAASGSGSGSLIGASDGVAADADGGTSSSESESTTTTSHSIGERRKKTVVKSAAHGAAADQSNSSYTCDLCQLCFDSQELLQSHIKSHFLNGPSAGSGSANASGSSSSRGASLGGGSGSASGSRNNNHNNNNIDSSSSGSSSCSSSSSSNNKTKTKKSGLDAIKSGSAAATASTTTSTATTTTTAKGAAEAAATTAAADAANSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
iTF_00506259;
80% Identity
-