Dezo014720.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ezoana
Gene Symbol
ftz-f1
Assembly
GCA_035045725.1
Location
JAWNOU010000177.1:7760246-7773400[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.28 2.8e+03 -2.5 20.3 47 167 26 153 5 158 0.55
2 3 1.6e-19 1.6e-15 57.6 0.5 1 79 318 395 318 417 0.75
3 3 2.5e-72 2.5e-68 231.5 1.2 157 408 526 770 494 772 0.90

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCCACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCGTTTAGCATGCAGCTcgaccagcagcagcccgcGAGTCCAGCGCagagcaacaccaacaacaacagcaacaataacagtggcaacaataacagtggcaataacagcagcagcaacaacaacaacgataacgaTACAAACGCCTTGAGCAATTCCGATAACGATTACAGCGCCTACACGCTGCAATTGGGaaatcatcagcagcagcaacaacaacatcacacgcatcaccagcaacagcagcaacaacaacaacaacaacattaccaacaacaacagaatattgccagcaacaacacgaATGCCGCGAACCAATTCAACGCCTCCTCTTACTcgtatatatacaatttcgATTCACAGTATATATTTCCGACAGGGTATCAGGAAACGAACTCATCTCATTCGCAGCAAAGCGGCAACGGAGCTGGCAACGCGGCGGCTGGCAACTCTGGCCAGCTGCTgaatggcggcggcagcggcgctgCGGGCAACGGTTatatgctgctgccgccgggcGCTGGCGGCGCCTCGGCTGCACACATGTCCGGCAGCGTGGGCGGCAGCGGTGCGGCGGGCGGCGCTGGCGGTGCGGGTGGCGCTGGTGGGGGGCATCATGGCGGGACGAGCGCCAGTTCGGGCGGCGGCGAGGCCATCGACTTTAAGCACCTGTTCGAGGAGCTGTGCCCCGTCTGCGGCGACAAGGTGAGCGGCTATCATTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTTCAGAACAAAAAGGTCTACACTTGCGTTGCGGAGCGCTCCTGCCACATCGATAAGACGCAGCGCAAACGTTGTCCATATTGTCGATTCCAAAAGTGCCTGGAGGTGGGCATGAAACTAGAAGCTGTTCGAGCGGATCGCATGCGCGGCGGTCGGAACAAATTTGGACCCATGTACAAGCGGGATCGGGCGCGTAAGCTGCAGGTGATgcgtcagcggcagctggcgctgcaggCGCTGCGCAGCTCGATAGGCACGGACATAAAGCCGACGCCGCTGTCGCCGGGCTATCAGCAAGCATATccaaatatgaatattaagcAAGAAATTCAAATACCTCAGGTATCCTCACTCACGCAATCGCCGGACTCGTCGCCCAGCCCCATTGCGATCGCCTTGGGCCAGGTGAATGCAGGCGCGGGCGGTGTGATAGCCACGCCCCTGAATGCTGGCAATTTGAGCGGCGGCAACGGGAACGGCGGCAGCTCCTCGCtgggcaatggcaacaacaacaccaacaacaacagcacaggcagcggcagcggcggcggcggcggcggcggcagtggAGGAGGCAACaacgccggcggcggcggcggaggtgGCAGCAACAATCTCGCCGACGGCCTGCAACGCAACGGAAAtagtggcaacagcaacagcaacagcagttgcCACGAAACCGGACCTGGATCTCTGCAGAACACAGCCGAATCGAAATTGTGCTTTGATTCTGGCACACATCCATCGAGCACAGCCGATGCGCTCATCGAGCCACTGAGGGTCTCGCCGATGATACGTGAGTTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAGCTCTTTGCGCTGCTGCAGAAGCAGACGTACAACCAGGTGGAAGTGGATCTCTTTGAGCTAATGTGCAAAGTGCTGGATCAGAATCTGTTCTCGCAAGTGGACTGGGCAAGAAACACAGTCTTCTTTAAGGACTTAAAGGTGGACGATCAGATGAAACTGCTTCAGCACTCGTGGTCGGACATGCTTGTGCTGGATCATCTGCATCATCGCATACACAACGGCCTGCCGGACGAGACGCAGCTGAATAACGGGCAGGTCTTTAACCTGATGAGCCTGGGCCTGTTGGGTGTGCCACAGCTGGGCGACTACTTCAACGAGTTGCAAAATAAGCTGCAGGACCTGAAGTTCGATATGGGCGACTATGTGTGCATGAAATTCCTAATACTTTTAAATCCAGATGTGCGTGGAATCGTGAACAAAAAGACCGTCGTGGAGGGTCACGAGAATGTGCAGGCTGCGCTGCTGGATTACACACTAACGTGTTATCCCTCGGTTAATGACAAATTCAGGAGGCTTTTGAACATACTACCGGAAATTCACGCCATGGCCGCACGGGGCGAGGAGCACCTGTACTCAAAGCACTGTGCCGGCAGTGCGCCCACGCAGACGCTGCTTATGGAGATGCTGCATGCCAAGCGGAAAGTGTAA
Protein Sequence
MLLEMDPQQATVQFISSLNLSPFSMQLDQQQPASPAQSNTNNNSNNNSGNNNSGNNSSSNNNNDNDTNALSNSDNDYSAYTLQLGNHQQQQQQHHTHHQQQQQQQQQQHYQQQQNIASNNTNAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSGNGAGNAAAGNSGQLLNGGGSGAAGNGYMLLPPGAGGASAAHMSGSVGGSGAAGGAGGAGGAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNAGAGGVIATPLNAGNLSGGNGNGGSSSLGNGNNNTNNNSTGSGSGGGGGGGSGGGNNAGGGGGGGSNNLADGLQRNGNSGNSNSNSSCHETGPGSLQNTAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVVEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00485910;
90% Identity
iTF_00547388;
80% Identity
iTF_00506164;