Dere012082.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila erecta
Gene Symbol
-
Assembly
GCA_000005135.1
Location
CH954181.1:7150911-7156719[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.011 0.74 10.4 0.3 1 23 1262 1285 1262 1285 0.95
2 13 7.5 5.3e+02 1.5 0.2 1 23 1432 1454 1432 1454 0.91
3 13 0.00017 0.012 16.1 2.7 2 23 1457 1478 1457 1478 0.97
4 13 6.5e-05 0.0045 17.4 0.2 3 23 1486 1506 1484 1506 0.98
5 13 5.4e-07 3.8e-05 23.9 4.1 2 23 1513 1534 1512 1534 0.97
6 13 5.1 3.6e+02 2.0 0.4 5 23 1547 1565 1545 1565 0.96
7 13 1.3 89 3.9 5.4 3 23 1572 1593 1570 1593 0.93
8 13 0.13 9.4 6.9 0.2 2 23 1604 1624 1603 1624 0.96
9 13 0.00014 0.0096 16.4 0.3 1 19 1630 1648 1630 1652 0.95
10 13 3.3e-05 0.0023 18.3 0.4 1 23 1660 1682 1660 1682 0.98
11 13 9.7e-05 0.0068 16.8 7.6 1 23 1688 1710 1688 1711 0.96
12 13 0.00021 0.014 15.8 6.5 1 23 1716 1738 1716 1738 0.98
13 13 0.0025 0.17 12.4 6.1 1 23 1744 1766 1744 1767 0.96

Sequence Information

Coding Sequence
ATGGTCGACAACAGCGTCCAATGCCCCGTGTGCACATTGTACCTGCATGCGGGAATGAATCTCTCCGATCACTTGGAGACGCATCCCAAGGAGCAAGTGATCAAGGCGCTGGTGCAGATGACGATCGTTGGAAACGGTGGCAACAGCATGGGTAGTGCTCTCGCTGCCGCCATGCTGACAGGAGGAACTGGAGGTGGAACCAGCGGCGGCGAAGCCAGTGCCGATGAGAAACCGGCAGTCTTATCACTACCTTCTGGCGGCGATGTCAAACCAGTCGTGGTCAATACCATATCAGCTGCAACAGCGCCTGTGCtgccaccagcaccaccacctcTATCCTCCTCCCTCGTGGCAGCCTGCTCCAACGGAGCCGCCTCTTCCACAACCAGCTCCACACCCACCTCCAACTCcgcaagcagcagcagcaaaccgAGCAATCCACCGATGAAAGCACTGAAATGCGCAACGGCCACGACTGAGGCGCGAGCCAGCGCCAGCGCCAGCACATCCGCACATCCCACCACGAGCAGCGCGTCCACTTTGTACCAGCCACCGCAGGTCACTCCGGATTACCGCttcaaccagcagcagcagtcacAGACGGCGGACTTTGGGCGTGGTGTCACCACCTCAACAGCCGCGCTGGTTATTCCACAAGTGCCTCAGCAGCACTTCCTCGCCAGCCATCAACAGCAGGCTCACTTTCCACATCAGCAGCAGAccccgcagcaacagcatcagcagcagcagcatcagcctGCTCTGAAATTCAGCTACGCCACAGCTTTGCCCCCACCTCCGCCGTTGCAGCTATTcacgcagcaacagcaggcagTTGCTCCACCGCAGACCCAGCAGCAATCGCACCAGAAACCACCTCCCGCCTATGGAGCCGCCATTAGTCAAATACGATCTCAGcacaaccaaaacaaacagcagccACAGTCGCAAAGTGTGGCGTTGCAACACAACCTAGCCCTGGCACCACCGACGACAACAGCGGCTTCCACTTCacatgcaactgcagctgtcAAGCAGCCCAGTAAGCCACATACGGAAGTATTCCTGAATCccccaccaccgccaccggcACAGCAACAGGTGCAGATCCACAATTTAGTGCAAAATCAGGGTCAACACCATCAGCATCCtcaccagcagcagtcgcagccgAGCCAGCAGAGTCACCAACAGGCCCCGAATTCGCAGACCTACGGATTAGGGGTCAGCAGTAGCTGCAGTTCCTCCAACAACCCCTCGACCTCGGGGTCGGGTCTTCGTGCGAATCGTCAGACAAATTCTCCGTTCGGAGCACTGCTTAATGCTGCAGCGGCTGTGGCCTGCGCATCGCCGGCCTGTTCAACCACTTCATCTTCGGTATTGCGGTATGCGGAATCACCGGTGGCACACTACCTTGAGCGGGAAAATGGTGACTTCATTGTCCAGGAGACACCGAAGCATATTGTGGAGTGTGTGGAGAAGGAAGACGGCGAGTTCTCCGTCATCGAGCGCATTTATCAATCCCCGCCGAGTGTTCTGCACATacacgatgatgatgaggatgacgAGGATGAAGAGGAGGAAGACGAGCATGAAGCGCCACCCGAGGAAGAGGACGGGGACGATGAGCGGGAGGAGAACAGTCACAGCCGTAATATGAGCAAGACAACGAAAAAGGCCCGTAAGACGAAGCCGAAGCGAGGCTCCAAGCGCATGTCGGACGAGGAGGAGTTTATGAGCCTTAGCAGCGGATGTGAGAGCGAGATGGAAAAAGAGCGTAAGCAGGAGCAGCCAAATGCCGCGGCATCATTACCACCTCCCTTGTGCACGGCTCCTTCAACGAGTGCTGCTGGAGCTTCCACCTCCAATCTGGCGGATAATCATTCCAATTCCGCGTCCAACTCCGCCTCCAATTCCAACTCCACCGCCACTACAAAGTCCAAGAAGAACCGGATTACTGTACTCAGCGATGTTCCGCTCAATATGAATGAGTACCTCCATTTGATGGGCAACATCGTAGCCTCCAGTCGTATTGGGGCAAGTCGACCGTTTGCGGCTGTGGCTCCTATACCACTCGTTAAGGTGGAGAAGGAAGAGCCCTTGGATGATTACGACAACGTGGCATTGGCCGCTAATGCCGAGCTGGAGCAGAAGCCCAGTCTTGAGCACGGTACTACCAGCGTTATTCGAATGGCAAGCACGGCTGCAGCGCCTACATCTGCAACGGCGACCGAAGTGTCTCCCGAGGATCTCACACAGCCGCCGCCCATGAAAGTCGAGGTCGAGGCGACCACCACATTGTTACCGCAGCGCTTTTCAACTCCCGCCCAGCATCGTGGGCCTAAGAAATTAGTCATCAAACCAAAACAACCAGCACCAGCGACTGCGACGACAACAAAAAAGACTGACACCCCATCTTCCCCCAGCAACAACCCATCCATATCAAGAGATCTGGTGCAGGTAAAGAGTGAGACCGTGGAGGCGCCAGCGCcgagcagtagcagtagcattCTGGAGAAGCACCTGACTACCAGCCGCAAACTGTTGCAGCATCACTCGGCGGTGAACGATGACGATGCTCGAGTGCTGTTGGAGTTTGCGAACTCGAAGCAGCCGCCGCCACTGGCCGCATCCAGCACCACTTTCGTGGTAAATGCCAGTGCAGGGTTTCCCTCGGCGGGGTCAGTTTTCgccagcagcagtagcagctgTTCCAAAGCACCGGCCAAGCCGGGCGAGGAGTACATCCTGCCGGACAACAACATGGACGTGGATGAGATTCTGCTATCCTCGTCGTCTTCCTACACCTCCTCCGCAGCCCAGGTGCAGAACACGTTACAGCCGCCGGACTTTAACTTTCTGTACCACCAGACCACTACCACGGCCACGACGGCCACATACTTCAATCCCTTCTCTaggcagcagcatcatcatcagcagcaacacggGGTCAGCGATGCCACCAATGCGGCCACTTTGGCTTCGTCGTCCAGCAATTCAATGGACCACGACTCGATGAATGCTACATTCCGGGTGGCCAAAACCCAATCGCTGCAGTCATGGTACCAGCAAGAGCCGGAGCACGATCCACAAAATCAGGGTGGTGCAGAATCGGGAACAGCCACTCCCTCCAATCAGAGTCAGGATGTGGTCAGCCACCAGCCCACTAACTTTAATGCTGCTCTAGCGGCCGTCGATTGCTGTAGCGTTGCTTTGGACGAGGATGCAAAATATCTGGACCTGGACGCCTGCAAGCGGGAGCagctgagcagcagcagcaacctgCCCTCCGCCTCAGCGTCCACAACGTCGTCGTCGTTCGCTGGTGCTGGCACGGAAAGCAGTTTGGTGGGTGGTCTGAATATCCGCACCGATGAGAAGATGCCCGCCAAGGGAGAAATCTCCGAGCAGGAGAGCAACTGCGACATCGAGAACTCCTGGAGTGAATCGGTTTATGGGGATATTTCTCAGCGGTATTTCAGAAACCAGTTTTCTGGCGGCTACAACCCTGATTGGCGACAGGATTATTATCCGGCTCAGGATCTCAGCGCTCAGCAGAGGGAGCAAAAACGTTTTGACTTTAATGCTGTTGATGATGAGGCTTCATCTAGCACGCGTAGGAGCCATCTGGCAGATGTCCTCCCGACAGCGGCCACCTCTTCTGCATGTACGTCATCGGCTATGCTGGCGGGTCCACCCATAGCTTCGACATCACGGGCTGCTGCTGAGGCGGCAGCGGAGGCGGCTGCTCTTGCCCAGCGGAAACCGCAGCGCCGCAAGCTCTACAAGTGTCCTCACTGCGAGGCGATCTTCGAAAAGCTTAAAGAGCGCAATGCGCACATGATTGGCGAGCACAACTACGTGCGGCAAAATCGGCGTCTAATTTGCACTCAGCCGCAAATCAATACTTCGATGTtgccgccacagcagcagaTGATGCTGCAGGCAGGTGAGGTTGAGGATTCCAAAGATGGCATTGTGAAGATAAAACAGGAGCAGTGCCAGGAAAAGCAGGATGTTGAACAAATGCACGACCATTCCGAACTCTTGGCTGATGTCAAGGACTCTGAGCTGATGGGCATCGGCGGTGATGGTGACTGTGATGCGGATGATGACATCAAGCCACCCAACCAGCTAGATGAAAAGCCAACGCTGCCGCCATTAGCCATGACGACGCCAGCAGCTAAGTTAGCAGCTTTGTATCGAATGCTCATCGCCTACAACGAATCCAAGCTCGGACAGGAGCGCAACAACCTTAGTGAGCTGGAGCAGAAGGCTATGGAAAAATCCATATTTCTCTGTTACGTCTGTCGTACCGATTTCCCGTCCGTAAAGCTCTATGACGCCCATCTCACTGAGCACCCGGCTGAATGCTTCACTTGCGGCAAGAAGTTCTACCGCTGGAAGAACTTCTCCCTACACCTTAAGCGGCACTTGGGCTGGAAGGAGTTCGGATGCTACGTTTGCGACAAGAAGTTCGTGGTGCGCAGCGCCTTGGTCGAACATATGCGGATGCACACGGGGCAAACACCTCTCAAGTGCAAGATATGCGGCAAAAAGTTCAAGCGATACTCGAATCTGACGCAGCACCGCAAGCGCCACACCAAAATGATGGTGCGCAAAAAGGAATACGTGTGCCACTGCGGTGAAGTTTTGCCCTCGAAGGCTCGCTTCCTGTGGCACAAGGAAACGCACGACCTGAAGCCGAAGTGCTGTCCGTACTGTTGCGATCGGTTTGTGCACGCCAACTCCCTACGCCGCCACATTCGGCTTGCCCACTCCGATAAGTTTGACTACGCCGAGCCTATGGAATGCCCTATGTGTAAGCAGATCTTCGCGAAGACGTCCATCAAGGCGCATATGGCGACGCATTCAACGGAGCCCCAATACGATTGCGCCATTTGTAGCAAGAGCTTCTCCACCAAATGGAATCTCAAGATCCACTCGTGGGTACACGCCAACCGGACAGCCAAGCCCTTTAAGTGCGAGTACTGCCCAAAAGCGTTCGTGCGAGAGCTAGACTTCAAGAACCACATCAACGCGCATAAGCAGATCAAGCCGTACACGTGCGAGTACTGCGGCTGCAAGTTCATCCGCAAGTACAACTACATGCGACACCGGCGCGAACATCACGGCACCAAGAAGTTCACCTGCGACCAGTGCGATAAGTCCTTCCATCGACACTACTATCTGATAGAGCACCGGCGAATGCACACCGGAGAGCGTCCGTTCACGTGCACCATCTGCGGCAAGAGCTCCACTACCAAGACCAACCACAACAAGCATCTGAAGATCCACCATTCGCGCGATCCGTTCACGGTGGAGGCCTAA
Protein Sequence
MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNGGNSMGSALAAAMLTGGTGGGTSGGEASADEKPAVLSLPSGGDVKPVVVNTISAATAPVLPPAPPPLSSSLVAACSNGAASSTTSSTPTSNSASSSSKPSNPPMKALKCATATTEARASASASTSAHPTTSSASTLYQPPQVTPDYRFNQQQQSQTADFGRGVTTSTAALVIPQVPQQHFLASHQQQAHFPHQQQTPQQQHQQQQHQPALKFSYATALPPPPPLQLFTQQQQAVAPPQTQQQSHQKPPPAYGAAISQIRSQHNQNKQQPQSQSVALQHNLALAPPTTTAASTSHATAAVKQPSKPHTEVFLNPPPPPPAQQQVQIHNLVQNQGQHHQHPHQQQSQPSQQSHQQAPNSQTYGLGVSSSCSSSNNPSTSGSGLRANRQTNSPFGALLNAAAAVACASPACSTTSSSVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEDEEEEDEHEAPPEEEDGDDEREENSHSRNMSKTTKKARKTKPKRGSKRMSDEEEFMSLSSGCESEMEKERKQEQPNAAASLPPPLCTAPSTSAAGASTSNLADNHSNSASNSASNSNSTATTKSKKNRITVLSDVPLNMNEYLHLMGNIVASSRIGASRPFAAVAPIPLVKVEKEEPLDDYDNVALAANAELEQKPSLEHGTTSVIRMASTAAAPTSATATEVSPEDLTQPPPMKVEVEATTTLLPQRFSTPAQHRGPKKLVIKPKQPAPATATTTKKTDTPSSPSNNPSISRDLVQVKSETVEAPAPSSSSSILEKHLTTSRKLLQHHSAVNDDDARVLLEFANSKQPPPLAASSTTFVVNASAGFPSAGSVFASSSSSCSKAPAKPGEEYILPDNNMDVDEILLSSSSSYTSSAAQVQNTLQPPDFNFLYHQTTTTATTATYFNPFSRQQHHHQQQHGVSDATNAATLASSSSNSMDHDSMNATFRVAKTQSLQSWYQQEPEHDPQNQGGAESGTATPSNQSQDVVSHQPTNFNAALAAVDCCSVALDEDAKYLDLDACKREQLSSSSNLPSASASTTSSSFAGAGTESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSESVYGDISQRYFRNQFSGGYNPDWRQDYYPAQDLSAQQREQKRFDFNAVDDEASSSTRRSHLADVLPTAATSSACTSSAMLAGPPIASTSRAAAEAAAEAAALAQRKPQRRKLYKCPHCEAIFEKLKERNAHMIGEHNYVRQNRRLICTQPQINTSMLPPQQQMMLQAGEVEDSKDGIVKIKQEQCQEKQDVEQMHDHSELLADVKDSELMGIGGDGDCDADDDIKPPNQLDEKPTLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTEPQYDCAICSKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEA*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00529734;
90% Identity
iTF_00591878;
80% Identity
-