Deoh002160.1
Basic Information
- Insect
- Drosophila eohydei
- Gene Symbol
- ftz-f1
- Assembly
- GCA_035045825.1
- Location
- JAWNOT010000028.1:4994024-5004973[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 2.4 1.4e+04 -5.0 18.6 45 165 34 149 7 158 0.45 2 3 1.5e-19 9.1e-16 58.3 0.1 1 80 316 394 316 439 0.78 3 3 2.4e-72 1.4e-68 232.2 1.1 154 408 514 761 485 763 0.92
Sequence Information
- Coding Sequence
- atgttattaGAAATGGATCCCCAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCACCGTTTAGCATGCAGCTTgatcaacagcagccagcgagTCCTGCACagagcaacaccaacaacaataacaataacagcagcagcagcggaaataacaacaacaataataatagcaacaatgaTAACGATTCAAATCCTTTAAGTAATGCCGATAACGATTACAGCGCGTATACGCTGCAGTTGGGCaaccatcaacagcagcaacaccaccaccaTAATAcgcatcatcagcaacaacaacagcaacattaccaacagcaacaacaacagaataTTGCCAGCAACAACGCGAATACTGCAGCGAACCAATTCAATGCCTCCTCTTATtcgtatatatacaatttcgaTTCACAGTATATATTTCCGACAGGCTATCAGGAAACCAACTCGTCACATTCGCAGCAAAGCGGCAACGGCACTGGTGTAGCATCTGCTAACTCTGGCCAGCTACTAAAcggaggcagcaacagctctgCCGGCAACGGTTATATGTTGCTGCCACCAGGTGGCGCTTCAGCTGCTCACATGTCCGGCAATGTGGCTGGCAGCGGAGCAGCTGGCGGAGCGGGCAATGTCGCGTCGACTGGAGTTGTTGGCGGTGGTCACCATAGTGGAACAAGCGCCACCTCTGGCGGTGGCGAAGCCATCGACTTCAAGCACTTGTTCGAGGAGCTGTGCCCTGTTTGTGGGGATAAGGTGAGCGGCTACCACTACGGCCTGCTCACCTGTGAGTCCTGCAAGGGCTTCTTCAAGCGGACCGTTCAGAACAAAAAGGTCTACACATGCGTTGCGGAACGCTCCTGCCACATTGATAAAACGCAGCGCAAACGTTGTCCATATTGCCGATTCCAAAAGTGCCTCGAAGTGGGCATGAAACTTGAGGCGGTTCGAGCAGATCGTATGCGTGGAGGCCGTAACAAATTTGGACCCATGTACAAAAGGGATCGGGCGCGAAAGTTGCAGGTGATGCGACAGCGGCAGCTTGCCCTGCAGGCTCTGCGGAGTTCTATAGGTTCAGATATAAAGCCAACACCGCTCTCGCCTGGCTATCAGCAAGCATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGGTATCCTCACTTACGCAATCGCCGGATTCGTCACCCAGCcccattgccattgctttGGGTCAGGTGAATGCTGGCGCTGGCGGTGTGATAGCCACCCCATTGAATGTGGGCAATTTAAGTGGCGGCAGCTCGCTAGGCAATGGGAACAGCAAcactaccaacaacaacacctcaggaagcagcggcggcggcggggGTAGTGGGGGTGGAAATAACTCTGGCGGGGGAAGCggtgccaacaacagcaataacattCCCGATGGCCTGCAACGTAACGGAAACAgtggcaatagcaacagcaacagcagctgccatgaAACCGGGAATGGATCTCTGCAGAACACAGCTGACTCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGGAGACGCGGTCATTGAGCCACTGAGgGTCTCGCCGATGATACGAGAGTTTGTGCAATCGATCGATGATCGGGAATGGCAGACTCAGCTTTTTGCGCTGCTGCAGAAGCAGACCTATAACCAAGTTGAAGTTGATCTCTTTGAGCTAATGTGCAAAGTGTTGGATCAAAATCTGTTCTCACAAGTGGATTGGGCAAGAAACACTGTCTTTTTTAAGGATTTAAAGGTGGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCGGACATGCTTGTGTTGGATCATCTGCATCATCGTATACACAATGGTTTGCCGGATGAGACGCAGCTGAATAACGGGCAGGTGTTTAACCTAATGAGCCTTGGCCTATTGGGAGTGCCACAGTTGGGAGACTACTTTAACGAGTTGCAAAATAAGCTGCAGGACCTGAAGTTCGATATGGGAGACTATGTGTGCATGAAATTCCTAATACTTTTAAATCCAGATGTACGTGGAATAGTGAACAAAAAGACCGTTGTGGAGGGACACGAGAATGTTCAGGCAGCTTTGCTGGATTATACACTTACGTGTTACCCCTCAGTAAatGACAAATTTAGGAGGCTTTTGAATATACTACCGGAAATTCACGCCATGGCCGCTCGCGGCGAAGAACATCTATACTCAAAGCATTGTGCTGGCAGTGCACCCACGCAGACGCTGCTCATGGAGATGCTGCATGCTAAACGAAAGGTGTGA
- Protein Sequence
- MLLEMDPQQATVQFISSLNLSPFSMQLDQQQPASPAQSNTNNNNNNSSSSGNNNNNNNSNNDNDSNPLSNADNDYSAYTLQLGNHQQQQHHHHNTHHQQQQQQHYQQQQQQNIASNNANTAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSGNGTGVASANSGQLLNGGSNSSAGNGYMLLPPGGASAAHMSGNVAGSGAAGGAGNVASTGVVGGGHHSGTSATSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGSDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNAGAGGVIATPLNVGNLSGGSSLGNGNSNTTNNNTSGSSGGGGGSGGGNNSGGGSGANNSNNIPDGLQRNGNSGNSNSNSSCHETGNGSLQNTADSKLCFDSGTHPSSTGDAVIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVVEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00479510;
- 90% Identity
- iTF_00532403;
- 80% Identity
- iTF_00502575;