Basic Information

Insect: Drosophila dives
Gene Symbol: zfh1
Assembly: GCA_035042365.1
Location: JAWNLJ010000411.1:241555-247472[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.7e-05 0.0019 18.5 1.0 1 23 150 172 150 172 0.97

2 15 0.00083 0.059 13.8 1.2 3 23 180 200 178 200 0.94

3 15 9.1e-05 0.0064 16.9 0.1 1 23 382 404 382 404 0.98

4 15 0.00031 0.022 15.2 0.9 1 23 410 432 410 432 0.98

5 15 0.0022 0.16 12.5 4.3 1 20 464 483 464 487 0.89

6 15 0.0084 0.59 10.7 3.0 1 23 534 556 534 556 0.94

7 15 0.0088 0.62 10.6 0.4 1 23 562 585 562 585 0.97

8 15 0.027 1.9 9.1 0.4 3 19 594 610 593 611 0.95

9 15 0.00016 0.011 16.1 5.7 1 23 620 642 620 642 0.97

10 15 0.041 2.9 8.5 1.2 2 23 648 669 647 669 0.96

11 15 9.2e-06 0.00065 20.0 1.0 1 23 678 700 678 700 0.98

12 15 0.001 0.074 13.5 0.1 3 23 708 728 706 728 0.97

13 15 5.6e-05 0.004 17.5 0.5 1 23 734 756 734 757 0.95

14 15 0.047 3.3 8.3 0.4 1 23 767 789 767 789 0.97

15 15 0.0015 0.11 13.0 0.4 1 23 1300 1322 1300 1322 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.7e-05	0.0019	18.5	1.0	1	23	150	172	150	172	0.97
2	15	0.00083	0.059	13.8	1.2	3	23	180	200	178	200	0.94
3	15	9.1e-05	0.0064	16.9	0.1	1	23	382	404	382	404	0.98
4	15	0.00031	0.022	15.2	0.9	1	23	410	432	410	432	0.98
5	15	0.0022	0.16	12.5	4.3	1	20	464	483	464	487	0.89
6	15	0.0084	0.59	10.7	3.0	1	23	534	556	534	556	0.94
7	15	0.0088	0.62	10.6	0.4	1	23	562	585	562	585	0.97
8	15	0.027	1.9	9.1	0.4	3	19	594	610	593	611	0.95
9	15	0.00016	0.011	16.1	5.7	1	23	620	642	620	642	0.97
10	15	0.041	2.9	8.5	1.2	2	23	648	669	647	669	0.96
11	15	9.2e-06	0.00065	20.0	1.0	1	23	678	700	678	700	0.98
12	15	0.001	0.074	13.5	0.1	3	23	708	728	706	728	0.97
13	15	5.6e-05	0.004	17.5	0.5	1	23	734	756	734	757	0.95
14	15	0.047	3.3	8.3	0.4	1	23	767	789	767	789	0.97
15	15	0.0015	0.11	13.0	0.4	1	23	1300	1322	1300	1322	0.98

Sequence Information

Coding Sequence: ATGAACAATCCGGACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGCCGACGACAGCGAAACAGAGATGACAGCAGCCTATTTGGTCAACGCTGCCGCCAATGGAAGCATTTCCAACGATGACGATCTCGATCATATGGCAGCCGAGAATCTCATCTTTATGGCACGCGATGGCCAACTGAGCGAAATTATCGCCGCAAATGAGGCAAAtggcggcagcagcacagTGCTAATCACGGACGGAAATAACGGTGTGGAATACGCCGAATCCTTTGACGACGATACCCAAGTCGTCACAGAGGAGATCATCACGGATGATTGGGTACAGCATCAGGGCGCAGAGCGtgtGGAAATTGCGGCGGAACAAATCGCTGGCAATGGCAGCTCGCAGGAGCTGTTGGACATGCAACAGAATGAATATATGGCGATGCGTCCCTATCCCTGTGACTTTTGCAGTCGACGCTTTCGGAAGAAGGCCAGCCTTAACAATCACATGCTGGCGCATCAGAATGATCGTCCCCATCTCTGCAAGCTGTGCGGGGCGCGTTTCTCGCGACGGGCAGAGCTCATTAGTCACTTCAAGGCGCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATTAAATTTGAGCcactacagcagcagcaacaccatcagcagcagcagcagcaactgcagcagcgacaaaTTGAGGATCATTTCTATGAGCACGAATGGCCGCTGTAtcaggaacaggagcaggaacCAGAGCAAGAGCATGAGCCGGAGCGGGAGCAGGTCGAAGAGCAACTGGAGCAAattgaggagcagcagcagctggagcagcatcagcaccTGATGCAACAATCGGTGGCCCCACCCACCGCTGCTCGTGGACGGATCAGTCGCTTGAAGCTCAAAGAGGAACAATATATTGTGATTGCCCCCGATAAACCGGAGACGGAGTTGCCTCAATACATGCATTGTGAAGCGAATTGCGATCAATCACttgccaccaacaacaacaacaaccaactcCAAGCGACGCCATCCAATGATGTTgcgactgcagctgctgctgatggggCACAGGGGCAGGCAACGTTGCGTTTTCCCGTGCTCGATGAGAGCAAACCCTTTGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCTCTCGTCTCCCACATCAAGAATCATCGCGTGGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAATTATAGTTTGCAGGAGCATCAGAAAACACATCAATTTGAGGAGAGCAACTCGGAATACGATCCCGCATCGGCGGGCGAGGAGGATACGGCGAGTGAATCGGAAGCGGAACAGCTTTACGGTGATTTTTACTGCGGCGAATGCGGCATCTCCTTTCACCGGCAGGATTTGTTGCGGCGTCACTGCAAACAGCAGCACAGCAAGCAGctaactgcaacaacagctggtggcaacaacaacagtgtggcaactgcaacagcaacggatGCAGTGTGCGTGGCGGCTGGAGCTGCAACTGATGccgatgctgatgctgttaATGCCAAAGATGCGCCACATTGTTGCCACACTTGTGGCAAATCATTTCCCAACGTACTCAAACTGCTCGCCCATGCCGAAATCCACAAACGTTTCCCGCCATTCAAATGTGTCCTGTGCGGAGTCAGTTTCTACGAGGAGCAGGCCATCAAGCGGCACCTGAGCACGCGGCATCCGCACGAGCTGAAGCAGAACtcgtgtgtgttgtgtggcaAGGAGTGCCGGGATCGGAAGGCGCTGATCAAGCATGCATGGGATCATTCGCGGGAGAAGTGCCACTCGTGCTCCAAGTGTGGTAAGAATTTCCACAACAAGGGGCGCCTGAAGCGGCACATGGCATCGCATCGCGACAAATCCGTCGTGTGTGAAGTGTGCCACGAGGAGTTCCCCGACGGACGCACTTTGTCCAACCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAAATGTTTCCCTGCCACGAGTGTGGCAAGACCTTTGGGTCGCGCAGCTCGCAGCAGATTCACGTGCGCATCCACACGGGTGAAAGGCCCTACGGTTGTCGGTACTGCTGGAAGGCCTTCGCCGATGGCGGCACTCTCCGCAAACACGAGCGCATCCACACCGGCGAGAAGCCCTACGCCTGCTCCGTCTGTCCGCGTGCCTTCAATCAGCGTGTCGTCCTGCGGGAACACATCCGATCGCATCATTCGGGTCTGGATGTGGCCCGTGGCACGTATCATTGCACGGTCTGCTCGGCGGATTTGAGCTCATCAAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACGAACACAGCCAAACAGCGACAGCCAATTACTGGTCCACGTAAATACAAACGTCGCCGGAAACTGCAGCCGCATGAAATTGCGCATATGCGCGCCGAGCACAAGGCTGGCGGCGTCGATGGCGAGGttggggaggaggaggattaTGTGAGCGACTTGGACTATTGCGATCTGGATGTGGAGAATGTGGATGAGTTGCTGCAGGAGGCAACCGCAGAGCCACCACCACCCACCAAAAAAGCGAAACGCAAACGCAAAGCTCCAATTAAATCAGGCGATGAGCAAAGGTTGTGGGATGAGAAATTCCTGCAGCAGGCGAGTAATGGAAACAGCGATGAGGCCTACAAAAGTTTCTTTCAAATGGACTCGCTGGTGGTGGTCAATGATCAAACGTTGCAGCCCGTTGATGCTGCCACCACCAAGTTGCAGCAGGCTGAGATTAAGGAGCAAAAACTGAAAGCaggcagtcgcagcagcaaaagaagggCTGCAAAAGCTGgcggaggagcagcaggagcaggtggaggaggtggaggaggagctgctgctgctccacgtCCACGCATGATACACACGGCCAAGTCGCAGCAGACAACTTCAAAGAAATCCCGCACAAGGAGTTATATCACACGCACCAGCACcaatgaacagcagcagcagcagggaagaggaggaggagcaagTGGAGGAAGCCTTATCAAATCGCGCATTGTGGATGACTATGAGATCATCTCACCGGCCACACAGCCACCCAATCAAATCAGCTCCAGTCCACTGCACATCAAACAGGAGCAggaacatcatcatcatcatcagcatcagcagcatcatcatcagcagcagcagcaacgagtACAGCTGCTCTTTGATGACAGCCATCTGCTCATCGATCCGGGCCTGTTGCGTGAGAAGACCTATGAGAAATATAACCCCAGCATTGTTCAAGATCTCGAGGAGATTTTGCGTAGTCCCCCCAAGCATGAGCGGGACGATCGACGGCTGCGCTTCACCAGCGAATCGTCCACGACGCCACAATTTCTGCCCGGTGAGGAGGAGGAACAGCATCTCATTAAGATCGAGCCAACGTCGCCGGATCTCCGAGAAATGGTCGAgagccagcagccagccacACTGGCAGCGTCCTCCTCCGTCCGCTCCACGTCAGCACGCACATCCCGCCACCTGCGTCAGCTGACTGCAAAAGGTTCCAGTTCCGGTTCCATTTTGACTGCCACTTCCAGTTCCAGTGCCACTACCAGCACGCGATCCGCTTCCAAGCGCAATGCCAGCAAACAACTTTCCAAGAAATCCActtccaacagcaacaagggCAACTCATCATCTTCTTATCTCAACTACGGCGTTGACTCTTACCATGTCGGCGTGGTGGCCAGTGCCACTAGCTCCTCGGATGTCAGTTCCGGTTTCTTTTCCATCTCCGAGGTCGTCTCGGCGGCAGACGCAGCGGATGCAGCTGCAaaggcggcggcagcagccagcaaaacGGAGCGAAAAACGCGTTGTTTTGAGTGTGAAATGTGCTCGTCCAATTTTCCAGATCGTGCCCAGCTGCTGgaacacatgcatatacacatCTAG
Protein Sequence: MNNPDYGGIQWIQQESSAVADDSETEMTAAYLVNAAANGSISNDDDLDHMAAENLIFMARDGQLSEIIAANEANGGSSTVLITDGNNGVEYAESFDDDTQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADEEAAAAAIKFEPLQQQQHHQQQQQQLQQRQIEDHFYEHEWPLYQEQEQEPEQEHEPEREQVEEQLEQIEEQQQLEQHQHLMQQSVAPPTAARGRISRLKLKEEQYIVIAPDKPETELPQYMHCEANCDQSLATNNNNNQLQATPSNDVATAAAADGAQGQATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEDTASESEAEQLYGDFYCGECGISFHRQDLLRRHCKQQHSKQLTATTAGGNNNSVATATATDAVCVAAGAATDADADAVNAKDAPHCCHTCGKSFPNVLKLLAHAEIHKRFPPFKCVLCGVSFYEEQAIKRHLSTRHPHELKQNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKGRLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKMFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGVDGEVGEEEDYVSDLDYCDLDVENVDELLQEATAEPPPPTKKAKRKRKAPIKSGDEQRLWDEKFLQQASNGNSDEAYKSFFQMDSLVVVNDQTLQPVDAATTKLQQAEIKEQKLKAGSRSSKRRAAKAGGGAAGAGGGGGGGAAAAPRPRMIHTAKSQQTTSKKSRTRSYITRTSTNEQQQQQGRGGGASGGSLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHHHHHQHQQHHHQQQQQRVQLLFDDSHLLIDPGLLREKTYEKYNPSIVQDLEEILRSPPKHERDDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPATLAASSSVRSTSARTSRHLRQLTAKGSSSGSILTATSSSSATTSTRSASKRNASKQLSKKSTSNSNKGNSSSSYLNYGVDSYHVGVVASATSSSDVSSGFFSISEVVSAADAADAAAKAAAAASKTERKTRCFECEMCSSNFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: iTF_00499020;
80% Identity: -